Games |
- Uno 1.0.5 - Simple, basic text editor.. (Free)
- Studiometry 9.0.3 - Keep track of every aspect of your projects; nightly builds available.. (Demo)
- AMPPS 1.4 - Auto-install stack with Apache, Mysql, PHP, Perl, Python.. (Free)
- Super Crate Box (iOS)
- Molecules, Vol. 17, Pages 584-597: Mixed Biopolymer Systems Based on Starch
- Molecules, Vol. 17, Pages 571-583: A Facile Solvent Free Claisen-Schmidt Reaction: Synthesis of α,α′-bis-(Substituted-benzylidene)cycloalkanones and α,α′-bis-(Substituted-alkylidene)cycloalkanones
- Polymers, Vol. 4, Pages 150-186: Optical and Physical Applications of Photocontrollable Materials: Azobenzene-Containing and Liquid Crystalline Polymers
- Polymers, Vol. 4, Pages 134-149: Color-Tunable Etalons Assembled from Poly (N-Isopropylacrylamide) Based Microgels
- Polymers, Vol. 4, Pages 116-133: Preparation and Applications of Amylose Supramolecules by Means of Phosphorylase-Catalyzed Enzymatic Polymerization
- Polymers, Vol. 4, Pages 72-115: Phase Diagrams for Systems Containing Hyperbranched Polymers
- Sensors, Vol. 12, Pages 650-685: Multipath Routing in Wireless Sensor Networks: Survey and Research Challenges
- Sensors, Vol. 12, Pages 632-649: Toward Sensor-Based Context Aware Systems
- Shippin' Out Jan. 8-14: Amy, Zen Pinball 3D
- Aussie study finds link between excessive gaming and anxiety
- Blizzard rep denies Diablo III launching Feb. 1 - Retail Radar
- Sensors, Vol. 12, Pages 612-631: Aptamers and Their Biological Applications
- Polymers, Vol. 4, Pages 46-71: Antimicrobial Polymers in Solution and on Surfaces: Overview and Functional Principles
- IJMS, Vol. 13, Pages 628-650: Polyphenol Content and Modulatory Activities of Some Tropical Dietary Plant Extracts on the Oxidant Activities of Neutrophils and Myeloperoxidase
- IJMS, Vol. 13, Pages 612-627: A New Strategy for Identification of Highly Conserved microRNAs in Non-Model Insect, Spodoptera litura
- Bookends 11.2.3 - Reference management and bibliography software.. (Demo)
| Uno 1.0.5 - Simple, basic text editor.. (Free) Posted: 09 Jan 2012 03:21 AM PST  Uno is a simple, yet basic text editor for Mac: it has almost all the base functions you would expect from an editor like TextEdit. Starting from a blank window you can do practically anything with your characters. As it is a pure text editor it doesn't work with images or photos you'd like to put in your text. It does open Rich Text Format files (.rtf) and Unicode-formatted Plain Text files (.txt): it saves both as .rtf. Note for Mac OS X 10.5 Leopard users: although this is a Universal app, it has not been tested carefully on Leopard thus it could run with some issues. Version 1.0.5 (Jan.7, 2012):
Mac OS X 10.7 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Studiometry 9.0.3 - Keep track of every aspect of your projects; nightly builds available.. (Demo) Posted: 09 Jan 2012 03:01 AM PST  Studiometry can store information about clients, contacts, projects, to dos, payments, timers, invoices, reports, employees and more. It features networking, multiple employee support (with permissions and hour tracking), simultaneous search of all data, multiple currencies (with automatic exchange rate updating), multiple contacts per client, project and client statuses and categories, modifiable taxes, and many more features. Download is a 30-day trial. Pricing is for a single-user pack. Multiple user packs start at $925 for 5 users. Version 9.0.3:
Mac OS X 10.4 or later Download Now |
| AMPPS 1.4 - Auto-install stack with Apache, Mysql, PHP, Perl, Python.. (Free) Posted: 09 Jan 2012 02:55 AM PST  AMPPS is an easy to install software stack of Apache, Mysql, PHP, Perl, Python and Softaculous auto-installer that can be used on Desktops and office servers. AMPPS enables you to focus more on using applications rather than maintaining them. With AMPPS you can create a website by installing any of the 260 Apps, customizing it, and then simply publishing it on the internet via a wide choice of hosting service providers. Using AMPPS with Softaculous on your desktop, you get the same powerful database engine, and environment that your Web site uses on the internet. This ensures that your transition from development to production is smooth and seamless.AMPPS with Softaculous connects you to a world of popular and free open-source Web applications, including Joomla!, WordPress, Magento, Dolphin and more. Simply select your favourite script, and it handles the downloading and installation of your new Web site. Version 1.4: The current version of AMPPS for Mac includes:
Mac OS X 10.6.2 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 08 Jan 2012 07:47 PM PST [Platform: Mobile (iOS)] Hey, Super Crate Box, the awesome arcade and shooting game released by Vlambeer way back in 2010. What are you doing on the iTunes App Store? What's that? Being as awesome as the PC/Mac downloadable version? Sounds great! With handfuls of unlockables, perfectly-tweaked touch controls, and a constant worldwide tally of crates collected, you'll be short on excuses not to play this lovely, crazy little game. |
| Molecules, Vol. 17, Pages 584-597: Mixed Biopolymer Systems Based on Starch Posted: 09 Jan 2012 12:00 AM PST A binary mixture of starch–starch or starch with other biopolymers such as protein and non-starch polysaccharides could provide a new approach in producing starch-based food products. In the context of food processing, a specific adjustment in the rheological properties plays an important role in regulating production processing and optimizing the applicability, stability, and sensory of the final food products. This review examines various biopolymer mixtures based on starch and the influence of their interaction on physicochemical and rheological properties of the starch-based foods. It is evident that the physicochemical and rheological characteristics of the biopolymers mixture are highly dependent on the type of starch and other biopolymers that make them up mixing ratios, mixing procedure and presence of other food ingredients in the mixture. Understanding these properties will lead to improve the formulation of starch–based foods and minimize the need to resort to chemically modified starch. |
| Posted: 09 Jan 2012 12:00 AM PST Solvent-free Claisen-Schmidt reactions of cycloalkanones with various substituted benzaldehydes (aryl aldehydes) using solid NaOH (20 mol%) and applying a grinding technique were studied. Quantitative yields (96–98%) of α,α-bis-(substituted-benzylidene)cycloalkanones were obtained. Aliphatic aldehydes also provided α,α-bis-(substituted-alkylidene)cycloalkanones in very good yields with minor amounts of a-(substituted-alkylidene)cycloalkanones. The catalytic performance of solid NaOH was examined. The molar ratio of NaOH was optimized. The catalytic effect of solid NaOH was also evaluated by comparing it with KOH, NaOAc, and NH4OAc and it turns out that 20 mol% of solid NaOH was good enough to catalyze the Claisen-Schmidt reactions of cycloalkanones with various substituted benzaldehydes. Additionally, the regioselectivity of the Claisen-Schmidt reaction of acetone with benzaldehyde was examined. Using the same method, we could synthesize the corresponding bis-benzylidene- and mono-benzylideneacetone separately in 98% and 96% yields, respectively. |
| Posted: 09 Jan 2012 12:00 AM PST Photocontrol of molecular alignment is an exceptionally-intelligent and useful strategy. It enables us to control optical coefficients, peripheral molecular alignments, surface relief structure, and actuation of substances by means of photoirradiation. Azobenzene-containing polymers and functionalized liquid crystalline polymers are well-known photocontrollable materials. In this paper, we introduce recent applications of these materials in the fields of mechanics, self-organized structuring, mass transport, optics, and photonics. The concepts in each application are explained based on the mechanisms of photocontrol. The interesting natures of the photocontrollable materials and the conceptual applications will stimulate novel ideas for future research and development in this field. |
| Posted: 09 Jan 2012 12:00 AM PST Photonic materials (PMs) that are capable of manipulating and controlling light in systems have immense potential for the computing and communications industries. These materials are formed by assembling components of differing refractive indices in a periodic array. Light then interacts with this assembly, which results in constructive and destructive interference, and hence color. While many three-dimensional PMs have been reported, and have the most potential for the applications mentioned above, one-dimensional PMs have a multitude of potential uses, e.g., light filtration. In this review, we focus on one-dimensional PMs; specifically poly (N-isopropylacrylamide) microgel based etalons. The etalons can be fabricated to exhibit a single bright color, and because the diameter of the microgels is dependent on temperature and pH, the mirror-mirror spacing can be dynamically tuned; therefore the etalon's color is dynamically tunable. |
| Posted: 09 Jan 2012 12:00 AM PST This paper reviews preparation and applications of amylose supramolecules by means of phosphorylase-catalyzed enzymatic polymerization. When the enzymatic polymerization of α-d-glucose 1-phosphate (G-1-P) as a monomer was carried out in the presence of poly(tetrahydrofuran) (PTHF) of a hydrophobic polyether as a guest polymer, the supramolecule, i.e., an amylose-PTHF inclusion complex, was formed in the process of polymerization. Because the representation of propagation in the polymerization is similar to the way that vines of plants grow twining around rods, this polymerization method for the preparation of amylose-polymer inclusion complexes was proposed to be named "vine-twining polymerization". Various hydrophobic polyethers, polyesters, poly(ester-ether), and polycarbonates were also employed as the guest polymer in the vine-twining polymerization to produce the corresponding inclusion complexes. To obtain the inclusion complex from a strongly hydrophobic guest polymer, the parallel enzymatic polymerization system was developed as an advanced extension of the vine-twining polymerization. In addition, it was found that amylose selectively includes one side of the guest polymer from a mixture of two resemblant guest polymers, as well as a specific range in molecular weights of the guest PTHF. Amylose also exhibited selective inclusion behavior toward stereoisomers of poly(lactide)s. Moreover, the preparation of hydrogels through the formation of inclusion complexes of amylose in vine-twining polymerization was achieved. |
| Polymers, Vol. 4, Pages 72-115: Phase Diagrams for Systems Containing Hyperbranched Polymers Posted: 09 Jan 2012 12:00 AM PST Hyperbranched polymers show an outstanding potential for applications ranging from chemistry over nanotechnology to pharmacy. In order to take advantage of this potential, the underlying phase behaviour must be known. From the thermodynamic point of view, the modelling of these phase diagrams is quite challenging, because the thermodynamic properties depend on the architecture of the hyperbranched polymer as well as on the number and kind of present functional end groups. The influence of architecture can be taken into account via the lattice cluster theory (LCT) as an extension of the well-known Flory–Huggins theory. Whereas the Flory–Huggins theory is limited to linear polymer chains, the LCT can be applied to an arbitrary chain architecture. The number and the kind of functional groups can be handled via the Wertheim perturbation theory, applicable for directed forces between the functional groups and the surrounding solvent molecules. The combination of the LCT and the Wertheim theory can be established for the modelling or even prediction of the liquid-liquid equilibria (LLE) of polymer solutions in a single solvent or in a solvent mixture or polymer blends, where the polymer can have an arbitrary structure. The applied theory predicts large demixing regions for mixtures of linear polymers and hyperbranched polymers, as well as for mixtures made from two hyperbranched polymers. The introduction of empty lattice sites permits the theoretical investigation of pressure effects on phase behaviour. The calculated phase diagrams were compared with own experimental data or to experimental data taken from literature. |
| Posted: 09 Jan 2012 12:00 AM PST A wireless sensor network is a large collection of sensor nodes with limited power supply and constrained computational capability. Due to the restricted communication range and high density of sensor nodes, packet forwarding in sensor networks is usually performed through multi-hop data transmission. Therefore, routing in wireless sensor networks has been considered an important field of research over the past decade. Nowadays, multipath routing approach is widely used in wireless sensor networks to improve network performance through efficient utilization of available network resources. Accordingly, the main aim of this survey is to present the concept of the multipath routing approach and its fundamental challenges, as well as the basic motivations for utilizing this technique in wireless sensor networks. In addition, we present a comprehensive taxonomy on the existing multipath routing protocols, which are especially designed for wireless sensor networks. We highlight the primary motivation behind the development of each protocol category and explain the operation of different protocols in detail, with emphasis on their advantages and disadvantages. Furthermore, this paper compares and summarizes the state-of-the-art multipath routing techniques from the network application point of view. Finally, we identify open issues for further research in the development of multipath routing protocols for wireless sensor networks. |
| Sensors, Vol. 12, Pages 632-649: Toward Sensor-Based Context Aware Systems Posted: 09 Jan 2012 12:00 AM PST This paper proposes a methodology for sensor data interpretation that can combine sensor outputs with contexts represented as sets of annotated business rules. Sensor readings are interpreted to generate events labeled with the appropriate type and level of uncertainty. Then, the appropriate context is selected. Reconciliation of different uncertainty types is achieved by a simple technique that moves uncertainty from events to business rules by generating combs of standard Boolean predicates. Finally, context rules are evaluated together with the events to take a decision. The feasibility of our idea is demonstrated via a case study where a context-reasoning engine has been connected to simulated heartbeat sensors using prerecorded experimental data. We use sensor outputs to identify the proper context of operation of a system and trigger decision-making based on context information. |
| Shippin' Out Jan. 8-14: Amy, Zen Pinball 3D Posted: 08 Jan 2012 11:30 PM PST Short new release slate led by Lexis Numerique's survival horror game on XBL and PSN; Zen Studios' latest hits 3DS, and Choplifter HD takes off.
Late last week, Warner Bros. delayed Gotham City Impostors from its scheduled January 10 debut, bumping the week's biggest release to February. That move leaves downloadable titles Amy, Zen Pinball 3D, and Choplifter HD as the main draws this week. Leading the group is survival horror title Amy on Xbox Live and the PlayStation Network. The game is set after a comet crashes into the earth, releasing a disease that spreads to the populace. Players control a woman named Lara, working alongside an 8-year-old autistic girl named Amy to escape the horde of infected. Amy was developed by VectorCell Studios, and hits the PSN on January 10 for $13, and Xbox Live on January 11 for 800 MS points ($10). Also out this week is Zen Pinball 3D for the 3DS. Available on January 12 for $7, the game includes four themed tables: Earth Defense, Shaman, Excalibur, and El Dorado. In addition to the expected added visual dimension, Zen Pinball 3D sports multiplayer functionality, online leaderboards, multiple viewpoints, and table-specific missions. The last notable new release this week is Choplifter HD on Xbox Live and PSN. A revamp of Broderbund Software's original Choplifter franchise, Choplifter HD will see players assume the role of a pilot for the elite, international helicopter rescue team C.H.O.P.R. (Coordinated Helicopter Operations, Preservation, and Rescue). For further details, visit GameSpot's New Releases page. The full list of downloadable games on the PlayStation Store, Xbox Live Marketplace, and Wii Shop Channel will be revealed later this week. Release dates are based on retailer listings and are subject to change. Tuesday, January 10 Wednesday, January 11 Thursday, January 12
Read and Post Comments | Get the full article at GameSpot "Shippin' Out Jan. 8-14: Amy, Zen Pinball 3D" was posted by Eddie Makuch on Sun, 08 Jan 2012 23:30:13 -0800 |
| Aussie study finds link between excessive gaming and anxiety Posted: 08 Jan 2012 07:27 PM PST Preliminary results for Victoria University study reveals those who spend more than 30 hours a week playing games have higher levels of stress and anxiety. Last November, Victorian PhD student Daniel Loton put the call-out for participants in an ongoing global study into the long-term effects of video game addiction. The first wave of preliminary results from that study--conducted by Loton and Victoria University--have now revealed that excessive video game playing is associated with higher levels of anxiety and depression.
 In the first wave of the study, Loton surveyed just over 100 participants over a nine-month period in order to measure variables such as stressful events and life satisfaction, as well as things like parenting, working, studying, and romantic relationships. Participants were asked to complete regular diary entries to measure how games impact various aspects of their life. The study's preliminary results compared the answers of excessive gamers (those who admitted to spending more than 33 hours on average a week playing video games) with those of more casual players (21 hours on average a week playing video games). The excessive gamer group--made up of around 30 participants--reported 15 per cent more stress and anxiety, and 25 per cent more depression than the casual players group. "Both groups averaged levels of stress, anxiety, and depression well above norms reported in past studies," Loton said. "But most alarming was that excessive gamers scored more than half the maximum measure for each and enough to determine clinical significance."
 However, Loton's study revealed that excessive gaming did not negatively impact success or satisfaction at work or study. According to the study, excessive players showed marginally higher success in their studies, failing fewer subjects and scoring higher grade averages than they had intended. Loton says that while the preliminary results of the study do show a link between excessive video game play and lower mental health, further analysis is needed to determine the severity of the problems identified. The study is ongoing and requires more participants. To take part, visit the official site. Participation involves completing online surveys monthly for a short period, and all participants who complete the study go into the draw to win A$500. Read and Post Comments | Get the full article at GameSpot "Aussie study finds link between excessive gaming and anxiety" was posted by Laura Parker on Sun, 08 Jan 2012 19:27:06 -0800 |
| Blizzard rep denies Diablo III launching Feb. 1 - Retail Radar Posted: 07 Jan 2012 06:18 PM PST [UPDATE]: Pic showing Best Buy ad for Blizzard's latest with countdown clock for midnight launch just weeks away debunked by company representative.
[UPDATE] Hopes of an imminent release for Diablo III have been quashed. A Twitter post from Blizzard's Diablo III community manager Micah Whipple stated "Diablo III does not have a release date. Any store or person claiming otherwise is guessing." Original story: Blizzard Entertainment fans may not have to wait much longer for the debut of Diablo III. Joystiq is reporting on an ad for the game in a Minnesota Best Buy telling customers they can pick it up on February 1. The ad also features a countdown clock and notice of a midnight launch for Diablo III. Best Buy's web store also lists a February 1 launch for the game. The last official word from Blizzard was that the dungeon crawling PC and Mac action game would be released in "early 2012." As of press time, a Blizzard representative had not responded to GameSpot's request for comment. The first title in the series since 2001's Diablo II: Lord of Destruction expansion, Diablo III will add a variety of new features, character classes, and a new auction house system designed as "a new way for the company to pull revenues from the game." For more, check out GameSpot's previous coverage of Diablo III. Read and Post Comments | Get the full article at GameSpot "Blizzard rep denies Diablo III launching Feb. 1 - Retail Radar" was posted by Brendan Sinclair on Sat, 07 Jan 2012 18:18:59 -0800 |
| Sensors, Vol. 12, Pages 612-631: Aptamers and Their Biological Applications Posted: 09 Jan 2012 12:00 AM PST Recently, aptamers have attracted the attention of many scientists, because they not only have all of the advantages of antibodies, but also have unique merits, such as thermal stability, low cost, and unlimited applications. In this review, we present the reasons why aptamers are known as alternatives to antibodies. Furthermore, several types of in vitro selection processes, including nitrocellulose membrane filtration, affinity chromatography, magnetic bead, and capillary electrophoresis-based selection methods, are explained in detail. We also introduce various applications of aptamers for the diagnosis of diseases and detection of small molecules. Numerous analytical techniques, such as electrochemical, colorimetric, optical, and mass-sensitive methods, can be utilized to detect targets, due to convenient modifications and the stability of aptamers. Finally, several medical and analytical applications of aptamers are presented. In summary, aptamers are promising materials for diverse areas, not just as alternatives to antibodies, but as the core components of medical and analytical equipment. |
| Posted: 09 Jan 2012 12:00 AM PST The control of microbial infections is a very important issue in modern society. In general there are two ways to stop microbes from infecting humans or deteriorating materials—disinfection and antimicrobial surfaces. The first is usually realized by disinfectants, which are a considerable environmental pollution problem and also support the development of resistant microbial strains. Antimicrobial surfaces are usually designed by impregnation of materials with biocides that are released into the surroundings whereupon microbes are killed. Antimicrobial polymers are the up and coming new class of disinfectants, which can be used even as an alternative to antibiotics in some cases. Interestingly, antimicrobial polymers can be tethered to surfaces without losing their biological activity, which enables the design of surfaces that kill microbes without releasing biocides. The present review considers the working mechanisms of antimicrobial polymers and of contact-active antimicrobial surfaces based on examples of recent research as well as on multifunctional antimicrobial materials. |
| Posted: 09 Jan 2012 12:00 AM PST Young leaves of Manihot esculenta Crantz (Euphorbiaceae), Abelmoschus esculentus (Malvaceae), Hibiscus acetosella (Malvaceae) and Pteridium aquilinum (Dennstaedtiaceae) are currently consumed as green vegetables by peoples in sub-Saharan Africa, Latin America, Asia and their migrants living in Western Europe. Sub-Saharan peoples use Manihot, Abelmoschus and Hibiscus also in the folk medicine to alleviate fever and pain, in the treatment of conjunctivitis, rheumatism, hemorrhoid, abscesses, ... The present study investigates the effects of aqueous extracts of those plants on the production of reactive oxygen species (ROS) and the release of myeloperoxidase (MPO) by equine neutrophils activated with phorbol 12-myristate 13-acetate (PMA). The ROS production was measured by lucigenin-enhanced chemiluminescence (CL), and the release of total MPO by an ELISA method. The study also investigates the effect of the extracts on the activity of MPO by studying its nitration activity on tyrosine and by using a new technique called SIEFED (Specific Immunological Extraction Followed by Enzymatic Detection) that allows studying the direct interaction of compounds with the enzyme. In all experiments, the aqueous extracts of the plants developed concentration-dependent inhibitory effects. A moderate heat treatment did not significantly modify the inhibitory capacity of the extracts in comparison to not heated ones. Total polyphenol and flavonoid contents were determined with an HPLC-UV/DAD analysis and a spectroscopic method using Folin-Ciocalteu reagent. Some polyphenols with well-known antioxidant activities (caffeic acid, chlorogenic acid, hyperoside, rosmarinic acid and rutin) were found in the extracts and may partly explain the inhibitory activities observed. The role of those dietary and medicinal plants in the treatment of ROS-dependent inflammatory diseases could have new considerations for health. |
| Posted: 09 Jan 2012 12:00 AM PST The indigenous small non-coding RNAs, known as microRNAs (miRNAs), are important regulators of gene expression and many of them are evolutionarily conserved. Whether stem-loop RT-PCR, as a sensitive method, could be utilized to clone conserved miRNAs from non-model insects lacks information. Here, three miRNAs, sli-miR-14, sli-miR-2a and sli-bantam, were cloned from Spodoptera litura by stem-loop RT-PCR. Two groups of primers were designed, and one of them performed especially well and proved stable. The sequences of two highly conserved miRNAs, sli-miR-14 and sli-miR-2a were identical to those in Drosophila melanogaster. To validate the reliability of this strategy, pre-miR-14 and pre-miR-2a in S. litura as representatives were given as well; this shared high homology with those in D. melanogaster and Bombyx mori, and both mature sequences of sli-miR-14 and sli-miR-2a in their precursors shared 100% identity to the results shown by stem-loop RT-PCR. Moreover, expression patterns of these miRNAs were investigated by real-time quantitative PCR. Sli-miR-14 and sli-miR-2a could be detected successfully and their expression patterns showed similar characteristics with those in model insects, further suggesting stem-loop RT-PCR technology can be used for identification of highly conserved miRNAs in non-model insects. These results provide a simplified and efficient strategy for studying the structure and function of highly conserved miRNAs, especially some critical miRNAs in non-model insects. |
| Bookends 11.2.3 - Reference management and bibliography software.. (Demo) Posted: 08 Jan 2012 08:59 PM PST  Bookends is a full featured and cost-effective bibliography/reference and information management system for students and professionals. Access the power of Bookends directly from Mellel, Nisus Writer Pro, or MS Word (including Word 2011): Bookends allows you to scan your existing word processor files and automatically generate finished manuscripts with properly formatted bibliographies. You can also scan Apple Pages '08 or '09 and OpenOffice 3 files, or RTF files saved from any word processor. Bookends allows you to share your references over the Internet with anyone, on any platform! And with Bookends you can directly search and import references from numerous sources:
Or use a built-in browser to download references with pdfs and/or web pages. Also, with automatic searches of PubMed you can discover articles as soon as they're published. Bookends allows for powerful group-based searches, with static, smart, and virtual groups. Bookends also offers a robust assortment of file attachment features:
Sync your library with Bookends On Tap on your iPad, iPhone, or iPod touch, so that you have your references and pdfs with you, wherever you are.
Mac OS X 10.4 or later Download Now This posting includes an audio/video/photo media file: Download Now |
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