среда, 3 октября 2012 г.

Games

Games

Resident Evil 6: Capcom responds to PS3 crashes, offers short-term workaround

Posted: 03 Oct 2012 03:16 AM PDT

Some PS3 owners have been suffering a crash bug at the start of Resident Evil 6, rendering the game unplayable. The bug appears to be affecting those who

Bartender 0.9.13 - Organize your menubar apps.. (Demo)

Posted: 03 Oct 2012 02:59 AM PDT



Bartender lets you organize your Menu Bar Apps.

Features:

  • Lets you tidy your Menu Bar Apps how you want.
  • See your Menu Bar Apps when you want.
  • Hide the apps you need to run, but do not need to see.
  • Have the clean looking Menu Bar you deserve.
Bartender lets you organize your Menu Bar Apps, by hiding them, moving them to Bartenders Bar, or displaying the full menu bar, set options to have Menu Bar Apps show in the menu bar when they are updating, or have them always visible in Bartenders Bar.

There are loads of ways to configure Bartender to perform as you wish. Give it a go and find out.

Note: Bartender is free during beta.



Version 0.9.13:
  • Extends Beta period of version 0.9.12.


  • Mac OS X 10.6 or later
  • 64-bit processor


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Roccat Browser 2.7 - Fast Web browser with a variety of features.. (Free)

Posted: 03 Oct 2012 02:55 AM PDT



Roccat Browser is an amazing browser from the fludium family. Roccat Browser is an amazingly fast Web browser, which has some great features such as:
  • VisiTabs which gives a preview of the website in the tab.
  • Navigate Launchers- assign letters or words to navigate to webpages, there are already many preloaded ones
  • Ad-Remover built within the engine
  • Great internal engine effects, purple glows on inputs, hold down on text field for 5 seconds for them to enlarge.
  • Email-Previewer; tells you when a link is an email link and tells you the link
  • Change User Agents- View sites which need other browser, view apples videos which require Safari etc...
  • A choice of VisiTabs or normal tabs or both, a bookmarks bar which fully supports bookmarklets
  • Downloads files and programs really easily and fast
  • Gets 100/100 in the Acid3 test
  • New Download Manager and now has FullScreen Mode
  • Lovebyt.es integration for instant URL shortening.
  • Undercover Browsing
  • Social page sharing / online email sharing
  • eBuddy Widget (chat with your facebook, msn, yahoo messenger, ICQ and aim friends no matter what tab you are on)
  • English, French and German localization
  • Ability to Import Bookmarks
  • OS X 10.7 Lion fullscreen support
  • Roccat Munch cookie management
  • Auto reloader (5, 10, 15 or 30 seconds)
  • The amazing RClouds (beta) which allows you to backup your settings, open tabs, imported bookmarks, bookmarks, navigate launchers, history and much more. RClouds allows you to restore your backups to any Mac so your browsing session can be anywhere you want it to be!
  • RClouds Reset allows you to reset your browser to factory settings (especially useful when you've restored your data to a public computer.
  • Cinnamon on the RClouds now means faster updating as it intelligently looks for the servers with the least amount of traffic.
  • We have even purchased the rights of exclusivity with lovebyt.es so now only Roccat users can use the service!
Why not try Cookie Stumbler to manage Roccat's cookies in the most secure way?

Version 2.7:
  • 19 Bug fixes including the bug where PPC users could not see preferences.
  • Roccat Munch now supports the Retina Display Macs.
  • Various consistancy updates.
  • Improved Userscripting and CSS styling (now also availiable from the CustoRune preferences).
  • Mail Page added to the ConnectMenu and shortcut was added for Mail Page ( Alt Command M).
    Added translating features which are located in the ConnectMenu.
  • Roccat has been updated with Retina graphics!
  • Introducing Roccat Flick: you can now share websites wirelessly with your friends over a wireless network with other Roccat Users (from version 2.5) and now with our newly released Roccat:Connect for iPhone, iPod Touch and iPad!
  • We have been working very closely with the team at Lovebyt.es and we have drastically improved our Lovebyt.es integration. Now Lovebyt.es opens in an RClouds style menu and shortens the website's URL without taking you away from the website you were on.
  • We also have some exciting new social features, we have been working with the latest API's from Facebook, and now you can update your Facebook status from any website you are on. The new system launches an RClouds style menu where you can easily update your status.
  • We have also updated the "Share Page with Facebook" feature to a similar system so it no longer takes you away from the site you are on.
  • We have removed the scrollbar from VisiTabs giving much more room for the site previews, simply navigate through them with your trackpad or mouse wheel.
  • New Gestures: use a three finger swipe right on the FusedBar (address bar) or toolbar to reload a page, and a three finger swipe to the left on the FusedBar or toolbar to stop a page loading. You can also do a three finger swipe down from the FusedBar to bring up the Facebook Status menu.
  • We have added two new menu items, one to go to the first tab and one to go to the last tab, making it even easier to navigate your tabs.
  • We have intergrated Google Maps with FusedBar, simply type locate and then a location to search in google Maps for example "Locate Florida" will find florida on the map, or "Locate night clubs in New York" it will show all night clubs in New York on the map.
  • Roccat now supports the WebGL standard for capable Macs, WebGL is a context of the canvas HTML element which provides a 3D graphics API without the need for Plugins. This means you will be able to use the new Google Maps- MapsGL for a smoother experience.
  • Check this link to see some of the things you can do with the standard: http://www.webgl.com/category/webgl-games/
  • Improvements in performance, stability, speed and security.
  • We have made changes to the eBuddy widget, fixing the problem which caused it to recently stop working, the eBuddy widget now automatically loads it's content without you having to press a button, it now also has a brand new look making the interface more simplistic.
  • New Items have been added to ConnectMenu, you can now update your Facebook status, add a Bookmark, share sites with Roccat Flick straight from ConnectMenu. The Facebook and Twitter page sharing menus now have icons too.
  • We have added keyboard shortcuts for backing up and restoring from RClouds
  • Runecats Download Manager now understands Gigabyte files rather than displaying them in Megabytes, it's has also been future proofed to understand Terabyte files and even Petabyte files!
  • We have added two new options to Auto Reloader, adding a reload every 2 seconds option and a reload every 60 seconds option.
  • Visual changes across the whole app.
  • We have introduced a new beautiful html5 search page called RuneSearch:Beaut, we have added quick access to his by typing beaut into your FusedBar.
  • Modified the Roccat useragent fixing warning messages.
  • Added the ability to share page with Pinterest from the social menu.
  • We have also launched RClouds 2.0 which now supports Roccat:Connect devices, Roccat Flick and now backs up and restores faster than ever.


Mac OS X 10.5 or later

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Viruses, Vol. 4, Pages 1950-1983: Enhanced Heterosexual Transmission Hypothesis for the Origin of Pandemic HIV-1

Posted: 03 Oct 2012 12:00 AM PDT

HIV-1 M originated from SIVcpz endemic in chimpanzees from southeast Cameroon or neighboring areas, and it started to spread in the early 20th century. Here we examine the factors that may have contributed to simian-to-human transmission, local transmission between humans, and export to a city. The region had intense ape hunting, social disruption, commercial sex work, STDs, and traffic to/from Kinshasa in the period 1899–1923. Injection treatments increased sharply around 1930; however, their frequency among local patients was far lower than among modern groups experiencing parenteral HIV-1 outbreaks. Recent molecular datings of HIV-1 M fit better the period of maximal resource exploitation and trade links than the period of high injection intensity. We conclude that although local parenteral outbreaks might have occurred, these are unlikely to have caused massive transmission. World War I led to additional, and hitherto unrecognized, risks of HIV-1 emergence. We propose an Enhanced Heterosexual Transmission Hypothesis for the origin of HIV-1 M, featuring at the time and place of its origin a coincidence of favorable co-factors (ape hunting, social disruption, STDs, and mobility) for both cross-species transmission and heterosexual spread. Our hypothesis does not exclude a role for parenteral transmission in the initial viral adaptation.

IJMS, Vol. 13, Pages 12656-12664: Relation between Pro-inflammatory Cytokines and Acetylcholine Levels in Relapsing-Remitting Multiple Sclerosis Patients

Posted: 03 Oct 2012 12:00 AM PDT

Multiple sclerosis (MS) is a chronic inflammatory, demyelinating and neurodegenerative disorder. Since acetylcholine (ACh) is known to participate in the inflammatory response, we investigated the possible relationship between pro-inflammatory cytokines and acetylcholine levels in relapsing-remitting multiple sclerosis (RR-MS) patients. Levels of ACh and pro-inflammatory cytokines IL1-β and IL-17 were measured both in cerebrospinal fluid (CSF) and sera of 22 RR-MS patients in the relapsing phase and in 17 control subjects affected by other non-neurological diseases (OND). We observed higher levels of pro-inflammatory cytokines such as IL-1β and IL-17 in both CSF and serum of RR-MS patients compared to control subjects. Moreover, ACh levels were lower in CSF and serum of RR-MS patients compared to levels of control subjects. Although the relationship between high inflammatory cytokine levels and low ACh levels need to be further investigated in the future, our data suggest that IL-1β, and cytokines induced by it, such as IL-17 and ACh, may be involved in the pathogenesis of MS.

IJMS, Vol. 13, Pages 12629-12655: The Role of Glucose Transporters in Brain Disease: Diabetes and Alzheimer’s Disease

Posted: 03 Oct 2012 12:00 AM PDT

The occurrence of altered brain glucose metabolism has long been suggested in both diabetes and Alzheimer’s diseases. However, the preceding mechanism to altered glucose metabolism has not been well understood. Glucose enters the brain via glucose transporters primarily present at the blood-brain barrier. Any changes in glucose transporter function and expression dramatically affects brain glucose homeostasis and function. In the brains of both diabetic and Alzheimer’s disease patients, changes in glucose transporter function and expression have been observed, but a possible link between the altered glucose transporter function and disease progress is missing. Future recognition of the role of new glucose transporter isoforms in the brain may provide a better understanding of brain glucose metabolism in normal and disease states. Elucidation of clinical pathological mechanisms related to glucose transport and metabolism may provide common links to the etiology of these two diseases. Considering these facts, in this review we provide a current understanding of the vital roles of a variety of glucose transporters in the normal, diabetic and Alzheimer’s disease brain.

pgAdmin3 1.16.0 - Administration and development for PostgreSQL database.. (Free)

Posted: 03 Oct 2012 02:38 AM PDT



pgAdmin3 is a powerful administration and development platform for the PostgreSQL database, free for any use.

Version 1.16.0:
  • Add privilege support on aggregates.
  • Add inline function support on languages.
  • Add support for range types.
  • Move references table textbox to the third tab in dlgForeignKey.


Mac OS X 10.2 or later

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Golden Joystick Awards 2012: Best Racer category – who are you voting for?

Posted: 03 Oct 2012 01:59 AM PDT

As voting for the Golden Joystick Awards 2012 enters its final weeks, we take a look at each of the individual categories. Today is the turn of Best Racer

IJMS, Vol. 13, Pages 12608-12628: Genetic Diversity and Population Structure: Implications for Conservation of Wild Soybean (Glycine soja Sieb. et Zucc) Based on Nuclear and Chloroplast Microsatellite Variation

Posted: 03 Oct 2012 12:00 AM PDT

Wild soybean (Glycine soja Sieb. et Zucc) is the most important germplasm resource for soybean breeding, and is currently subject to habitat loss, fragmentation and population decline. In order to develop successful conservation strategies, a total of 604 wild soybean accessions from 43 locations sampled across its range in China, Japan and Korea were analyzed using 20 nuclear (nSSRs) and five chloroplast microsatellite markers (cpSSRs) to reveal its genetic diversity and population structure. Relatively high nSSR diversity was found in wild soybean compared with other self-pollinated species, and the region of middle and lower reaches of Yangtze River (MDRY) was revealed to have the highest genetic diversity. However, cpSSRs suggested that Korea is a center of diversity. High genetic differentiation and low gene flow among populations were detected, which is consistent with the predominant self-pollination of wild soybean. Two main clusters were revealed by MCMC structure reconstruction and phylogenetic dendrogram, one formed by a group of populations from northwestern China (NWC) and north China (NC), and the other including northeastern China (NEC), Japan, Korea, MDRY, south China (SC) and southwestern China (SWC). Contrib analyses showed that southwestern China makes the greatest contribution to the total diversity and allelic richness, and is worthy of being given conservation priority.

IJMS, Vol. 13, Pages 12598-12607: Preparation and Physicochemical Properties of Vinblastine Microparticles by Supercritical Antisolvent Process

Posted: 03 Oct 2012 12:00 AM PDT

The objective of the study was to prepare vinblastine microparticles by supercritical antisolvent process using N-methyl-2-pyrrolidone as solvent and carbon dioxide as antisolvent and evaluate its physicochemical properties. The effects of four process variables, pressure, temperature, drug concentration and drug solution flow rate, on drug particle formation during the supercritical antisolvent process, were investigated. Particles with a mean particle size of 121 ± 5.3 nm were obtained under the optimized process conditions (precipitation temperature 60 °C, precipitation pressure 25 MPa, vinblastine concentration 2.50 mg/mL and vinblastine solution flow rate 6.7 mL/min). The vinblastine was characterized by scanning electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, mass spectrometry and dissolution test. It was concluded that physicochemical properties of crystalline vinblastine could be improved by physical modification, such as particle size reduction and generation of amorphous state using the supercritical antisolvent process. Furthermore, the supercritical antisolvent process was a powerful methodology for improving the physicochemical properties of vinblastine.

Goleta's Teenage Chess Wizard

Posted: 03 Oct 2012 12:55 AM PDT

With the sun starting to set over Ventura on a Tuesday evening in June, about 20 people sat down across from each other inside a sparsely decorated classroom on the Church of the Foothills campus.

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PCalc 3.8 - Fully featured scientific calculator.. (Shareware)

Posted: 02 Oct 2012 08:59 PM PDT



PCalc is a fully featured scriptable scientific calculator for Mac OS X with support for hexadecimal, octal and binary calculations, as well as an RPN mode, programmable functions, and an extensive set of unit conversions.

A Dashboard Widget is included with the main application.

Version 3.8:

  • Added support for Retina displays.
  • Fixed a problem with the tax rate not saving.
  • Fixed a crash on startup when updating currency rates.
  • Fixed a problem dividing negative non-decimal numbers.
  • Various fixes for OS X 10.8 Mountain Lion.


Mac OS X 10.6.8 or later

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Opera 12.10.1615 - High-performance Web browser (beta).. (Free)

Posted: 02 Oct 2012 08:59 PM PDT



Opera is a fast, elegant and easy-to-use Web browser. Renowned for its performance, standards compliance and small size, Opera's cross-platform browser technology gives users a faster, safer and more dynamic online experience.

Version 12.10.1615:

Extensions, improved

  • Several new and improved APIs are included in this version of Opera including:
    • API for URL filtering
    • Context Menu API
    • Screenshots API
    • Resource Loader API
  • High-resolution Display Support: Improved support for all high-resolution displays, including Apple's new Retina Displays is included in this beta.
Web Specifications Support

Opera 12.10 beta will include changes in the Opera Presto 2.12 engine up to core-integration-point 388.

  • SPDY: Support for the SPDY ("Speedy") network standard is included in Opera 12.10 beta. SPDY was designed to cut down the time it takes for a webpage to load, while reducing some of the security risks posed by HTTP.
  • CSS3 Gradients, Transitions, Animations, and Transforms: All members of these specifications are now available without the -o- prefix and have been updated to the latest published versions.
  • CSS Site Compatibility: To improve site compatibility and interoperability, Opera 12.10 beta also introduces aliasing for a selection of prefixed CSS properties.
  • Fullscreen API: Fullscreen API support has been implemented and fully supports Draft 7 of the Fullscreen API specification
  • Page Visibility API: Basic support for the Page Visibility API specification has been added, including support for visible and hidden
  • WebSockets: Support for WebSockets has been updated in Opera 12.10 beta and is now enabled by default.
  • ICC Profiles: International Color Consortium profile support has been added, ensuring images look as the author intended
Improvements

Display and Scripting

  • Add onpaste to document
  • Add an href attribute to the widget element in config.xml
Fixes and Changes
  • The OS X version of Opera has been reverted to in-process plugins while stability issues stemming from the out-of-process plugin system are investigated and resolved


Mac OS X 10.5 or later

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JoyBidder eBay Auction Sniper Pro 1.9.2 - eBay auction sniper.. (Shareware)

Posted: 02 Oct 2012 10:32 PM PDT



JoyBidder eBay Auction Sniper Pro is an eBay Auction Sniper that is there to help if you're tired of staying up late in the night and you still lose that all-important auction in the last seconds?

This officially Mozilla-powered software snipes eBay auctions. It runs on your own computer, so your eBay login stays secure and local.

The Pro Edition also make it easy to search auctions, track price, and analyze eBay sales data, along with the following features:

  • Schedule snipe bid of eBay auctions
  • Supports 22 eBay sites including eBay motor
  • Supports bidding groups
  • Add auction by item numbers or from eBay item/search page
  • Supports multiple eBay IDs
  • Batch sniping
  • Wake up computer and snipe from Standby/Sleep
  • Add Auctions from embedded Web Browser
  • Sound/Email/SMS outbid alert
  • Minimize to System Tray and launch from Desktop shortcut
  • Override shipping fee
  • Quickly find items in the list
  • Copy item list to Excel
  • Integrated Google Translation



Version 1.9.2:
  • Fixed a bug that causes "Import Search Results" to fail.
  • Fixed a bug that for certain kind of eBay search, items from multiple result pages are not imported.


Mac OS X 10.4 or later

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The Best Garfield Falsh Animashun Collab Ever!

Posted: 03 Sep 2012 04:00 AM PDT

Musical Obesity

Posted: 03 Sep 2012 04:00 AM PDT

Juan: Video Game Expert

Posted: 03 Sep 2012 04:00 AM PDT

Trolls be Trollin'

Posted: 03 Sep 2012 04:00 AM PDT

SickVidz(TM) Myke 2

Posted: 03 Sep 2012 04:00 AM PDT

SickVidz(TM) Myke 1

Posted: 03 Sep 2012 04:00 AM PDT
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