среда, 22 июня 2011 г.

Games

Games

Games

Lunar Commander

Posted: 22 Jun 2011 03:51 AM PDT

This is a RTS game where you can build your mines and barracks, energy plants, etc, and make a great arme before the enemy arrives, then you need to..

Red Space

Posted: 22 Jun 2011 03:41 AM PDT

A deep space mine colony have been attacked by a vicious alien race! Point n' click your way to safety and save planet earth!

Australian Classification Demystified

Posted: 22 Jun 2011 12:18 AM PDT

Laura Parker speaks to an authorised assessor and the former deputy director of the Classification Board to get a rundown on how the Australian classification system works, and their opinions on the R18+ rating for games.

 

Read and Post Comments | Get the full article at GameSpot

"Australian Classification Demystified" was posted by edmondt on Wed, 22 Jun 2011 00:18:27 -0700

Deus Ex: Human Revolution Interview With Sebastien Bich

Posted: 22 Jun 2011 12:12 AM PDT

GameSpot AU's Crosshairs chats to marketing director Sebastien Bich about what we can expect from Deus Ex: Human Revolution, the four pillars of the Deus Ex experience, staying true to the franchise, and more.

 

Read and Post Comments | Get the full article at GameSpot

"Deus Ex: Human Revolution Interview With Sebastien Bich" was posted by edmondt on Wed, 22 Jun 2011 00:12:19 -0700

Red Faction: Armageddon Interview with Chad Greene

Posted: 21 Jun 2011 11:41 PM PDT

We spent some time with art director Chad Greene at E3 2010 to chat about Red Faction: Armageddon's new underground direction, as well as a bit about its enemy and level designs.

 

Read and Post Comments | Get the full article at GameSpot

"Red Faction: Armageddon Interview with Chad Greene" was posted by edmondt on Tue, 21 Jun 2011 23:41:02 -0700

Dead or Alive: Dimensions re-rated M Down Under

Posted: 21 Jun 2011 10:04 PM PDT

The Classification Board of Australia has reclassified Tecmo Koei's Dead or Alive: Dimensions following the revocation of its initial PG rating; the 3DS title is now rated M in Australia.

 

Earlier this month, the Classification Board of Australia revoked the PG (Parental Guidance) rating of Tecmo Koei's 3D fighter Dead or Alive: Dimensions after media concerns about the game's sexual content. The game was pulled from store shelves and made illegal for sale until its reclassification.

Today, the Aussie rating body reclassified the game with an M rating following distributor Nintendo's re-submission of the title. According to the classification report on the latest rating decision, the classifiers found the game's violent and sexual content to be of moderate impact, pushing it up into the M category. The new consumer advice of "violence and sexualised gameplay" has been added.

The game was initially classified on February 8, 2011. However, due to a number of national and international media reports highlighting concerns over under-aged female characters in the game, the Classification Board requested preliminary information from THQ--the game's initial distributor in Australia, and the company that first submitted the game for classification--to ascertain whether the content described in media reports was contained in the Australian version of the game.

However, during the recent reclassification process of the game, the Classification Board was satisfied that "within its context, none of the characters appears to be a child under 18 years". The report on the most recent decision describes how the nature of the sexual context impacted on the new M rating:

"The female characters are invariably depicted with large breasts and wearing clothing that accentuates their cleavage. The female characters are also depicted in short skirts…which allow for a female's clothed crotch to be seen. The Classification Board believes that due to the realistically depicted female forms, the outfits worn and the ability of the player to zoom in and take photos of specific body parts of characters within the game consumer advice of sexualised gameplay is appropriate at an M classification."

The problem with the game's initial PG rating came from a lack of information surrounding the contentious content of the game. Shortly after the game was initially submitted for classification, it was passed to Nintendo for distribution. However, both Nintendo and the Classification Board have confirmed that it was THQ which failed to supply this information at the time of the game's initial classification.

"The additional content that was provided to the Classification Board was not identified in the original application at the time of classification and the Classification Board decided that this content lent emphasis to the existing contentious elements and heightened the sexualised tone to the game, to the degree that the game would exceed a mild playing impact," a Classification Board of Australia spokesperson told GameSpot AU at the time.

According the rating body, the game was not demonstrated during the initial application process. When asked by GameSpot AU why this contentious material was withheld from the Board during the initial classification application, THQ responded with the following statement:

"THQ are not the distributor of this title. Tecmo Koei are the content creators on record and Nintendo are their chosen distribution partner for the title in question. Our recommendation is that if you are seeking information on this subject that you speak directly to these parties."

Read and Post Comments | Get the full article at GameSpot

"Dead or Alive: Dimensions re-rated M Down Under" was posted by Laura Parker on Tue, 21 Jun 2011 22:04:44 -0700

FoneSync for Android - Sony Ericsson 1.0 - Syncing utility for Sony Ericsson cellphones running Android.. (Commercial)

Posted: 22 Jun 2011 03:08 AM PDT



FoneSync for Android allows you to synchronise your contacts, calendars, music and photos with your Sony Ericsson Smartphone and your Mac. It works fast and easy using a USB connection and does not require annual fees or a cloud. The Mac application is already included in the download.

Version 1.0: Initial Release

  • Mac OS X 10.6 or later.
  • Sony Ericsson Smartphone running Android OS 2.2 or higher


Download Now

myMailBoy 1.1.1 - Heads-Up Display for your mailboxes.. (Shareware)

Posted: 22 Jun 2011 03:17 AM PDT



MOApp's myMailBoy is a cute way to keep an eye on your inbox.

Working in fullscreen mode (thanks to MenuAndDockless for example)?
Working with hidden Dock?
Unhappy with the tiny Dock badge of Mail.app?
Simply need more information than an unread count?

That's when myMailBoy comes into play.
myMailBoy periodically searches for new unread messages in your Mail.app Inbox and displays them incl. preview in an unobtrusive HUD on top of all other Apps - enabling you to decide what to do next.

Ignore them for now.
Answering them.
Deleting them or even mark them as junk mail.

myMailBoy is a Menu bar application with custom Global Hotkey and hidden Dock icon. You can customize its behavior to your needs and the shortcuts from Mail.app are available in myMailBoy, too…

Version 1.1.1:
  • added support for latest 10.7 build (1.1.1)
  • added Global Hotkey for Mail.app)
  • major update for Mac OS X Lion (1.1)
  • added support for 10.7
  • rewritten code basis
  • rewritten GUI elements

Please note that this is a major update for the upcoming Mac OS Lion. Some added features are Mac OS 10.7 only and some of the new features 10.7 has to offer are not available because there simply is no documentation provided by Apple yet.



Mac OS X 10.6.6 or later

Download Now

This posting includes an audio/video/photo media file: Download Now

LEAKED: UK copyright lobby holds closed-door meetings with gov't to discuss national Web-censorship regime

Posted: 22 Jun 2011 02:46 AM PDT

A group of UK copyright lobbyists held confidential, closed-door meetings with Ed Vaizey, Minister for Culture, Communications and Creative Industries to discuss a plan to allow industry groups to censor the Internet in the UK. The proposal has leaked, and it reveals a plan to establish "expert bodies" that would decide which websites British people were allowed to see, to be approved by a judge using a "streamlined" procedure. The procedure will allow for "swift" blocking in order to shut down streaming of live events.

Public interest groups like the Open Rights Group asked to attend the meeting, but were shut out, presaging a regulatory process that's likely to be a lopsided, industry-centric affair that doesn't consider the public. The process is characterised as "voluntary," but the proposal makes reference to the Digital Economy Act, which allows for mandatory web-blocking (thanks to the action of LibDem Lords who submitted a proposal written by a record industry lobbyist as an amendment to the DEA).

The Open Rights Group has a campaign to repeal the DEA that you can sign onto.

We would like confirmation from the government that these are genuine proposals which they are actively considering. We would also like to know what steps they will be taking to consider the views of organisations such as Open Rights Group, and those others who recently wrote to rights holders expressing their concern and requesting such proposals are made public.

So far these discussions have involved only rightsholders and Internet companies, with only in the most recent meeting involving Consumer Focus. (As Jim blogged yesterday, Consumer Focus' response to the proposals they discussed is here). This is a welcome concession. But it is a concession. Open policy making that takes on board the broadest range of views is not something within the gift of politicians but a responsibility they bear.

Premier League joins group lobbying for web blocking, proposing confused "voluntary" scheme - overseen by the courts (James Firth)

Rights holders' proposed voluntary website blocking scheme (Open Rights Group)

Response to 'Addressing websites that are substantially focused on infringement' working paper (Consumer Focus PDF)

This posting includes an audio/video/photo media file: Download Now

Pharmaceutics, Vol. 3, Pages 326-337: Interactions of Tenofovir, Lamivudine, Abacavir and Didanosine in Primary Human Cells

Posted: 22 Jun 2011 12:00 AM PDT

Certain triple nucleoside/tide reverse transcriptase inhibitor (NRTI) regimens containing tenofovir (TDF) have been associated with rapid early treatment failure. The mechanism is unknown, but may be at the level of drug transport. We measured the lipophilicity of the drugs [3H]-lamivudine (3TC), -didanosine (ddI), -TDF and -ABC. Peripheral blood mononuclear cells (PBMCs) were used to evaluate drug–drug interactions at the level of drug transport. PBMCs were measured for the expression of P-glycoprotein (P-gp), multidrug resistance-associated protein-1 (MRP-1) and breast cancer resistance protein (BCRP) by flow cytometry. The rank order of the lipophilicity of the drugs were ABC>>>3TC³ddI>TDF. The accumulation of [3H]-3TC, -ddI and -TDF were temperature sensitive (suggesting facilitated transport), in contrast to [3H]-ABC. ABC reduced the accumulation of [3H]-3TC, and cell fractionation experiments suggested this was mainly in membrane-bound [3H]-3TC. ABC/TDF and ABC/ddI increased the accumulation of [3H]-3TC and 3TC/TDF also increased the accumulation of [3H]-TDF. In contrast, none of the NRTI/NtRTI incubations (alone or in combination) altered the accumulation of [3H]-ABC and -ddI. PBMC expression of P-gp, MRP1 and BCRP were detected, but none correlated with the accumulation of the drugs. The high failure rates seen with TDF, ABC and 3TC are not fully explained by an interaction at transporter level.

Deliver 2.3.11 - Send files to remote and local destinations with email notifications and more.. (Demo)

Posted: 22 Jun 2011 02:51 AM PDT



Deliver is a complete solution to send and share files across the Internet and local networks easily. It supports FTP, MobileMe, Amazon S3 and other major services, and offers automatic e-mail delivery notifications, compression, delivery to multiple destinations and much more. The notification messages are based on variable templates and contain the download link to your file and other delivery details.

A hot folder version of Deliver, Deliver Express, is also available.

Key features:
  • Automate delivery to remote and local servers
  • Supports FTP, SFTP, WebDAV, MobileMe, Amazon S3, AFP, SMB and local destinations
  • Automatic e-mail notifications
  • Variable e-mail templates
  • Deliver files by e-mail
  • Send files to multiple destinations at once
  • Automatic .zip/.dmg compression
  • Create lo-res PDF and attach to e-mail
  • Attach files from specific subfolder to e-mail
  • Encrypt disk images with passwords
  • Detailed history of all deliveries
  • Add e-mails from Address Book.


Version 2.3.11:
  • Fixed an issue in which the Destinations window could redraw improperly.


Mac OS X 10.5 or later

Download Now

This posting includes an audio/video/photo media file: Download Now

sBackup 1.7 - Beautiful, simple and powerful way to backup your critical and valuable data.. (Demo)

Posted: 22 Jun 2011 02:49 AM PDT



sBackup is a beautiful, simple and powerful way to backup your valuable data.

sBackup is able to backup your:

  • set of user defined items (files & folders)
  • whole Home directory
  • Desktop
  • Documents
  • Email
  • Personal Preferences
  • Music
  • Pictures
  • Movies

Upload backups to FTP

You can also compress your backup as 7z archive or use SFX archive.

The revolutionary SFX (self-extracting) technology developed by Bit Per Second for Mac OS X is unique system for creating archives.

SFX Backup doesn't need any third-party applications to extract it self. It's a standalone application containing the backup data.



Version 1.7:

This posting includes an audio/video/photo media file: Download Now

TimeTracker 0.4.2 - Display the contents of your Time Machine backups.. (Free)

Posted: 22 Jun 2011 02:52 AM PDT

TimeTracker displays the contents of your Time Machine backups, and shows what's changed since the previous backup. TimeTracker is in an extremely early state, and is as such very unpolished.

Version 0.4.2:
  • Fixed a bug causing .spotlight_repair files in the Time Machine backup to cause TimeTracker not to work properly


Mac OS X 10.5 or later

Download Now

This posting includes an audio/video/photo media file: Download Now

Sensors, Vol. 11, Pages 6493: Correction: Yoshie, T. et al. Optical Microcavity: Sensing downto Single Molecules and Atoms. Sensors 2011, 11, 1972-1991

Posted: 22 Jun 2011 12:00 AM PDT

The coefficient of the expression of Equation (6) was not properly written.

IJERPH, Vol. 8, Pages 2366-2385: A Framework for Integrating Environmental Justice in Regulatory Analysis

Posted: 22 Jun 2011 12:00 AM PDT

With increased interest in integrating environmental justice into the process for developing environmental regulations in the United States, analysts and decision makers are confronted with the question of what methods and data can be used to assess disproportionate environmental health impacts. However, as a first step to identifying data and methods, it is important that analysts understand what information on equity impacts is needed for decision making. Such knowledge originates from clearly stated equity objectives and the reflection of those objectives throughout the analytical activities that characterize Regulatory Impact Analysis (RIA), a process that is traditionally used to inform decision making. The framework proposed in this paper advocates structuring analyses to explicitly provide pre-defined output on equity impacts. Specifically, the proposed framework emphasizes: (a) defining equity objectives for the proposed regulatory action at the onset of the regulatory process, (b) identifying specific and related sub-objectives for key analytical steps in the RIA process, and (c) developing explicit analytical/research questions to assure that stated sub-objectives and objectives are met. In proposing this framework, it is envisioned that information on equity impacts informs decision-making in regulatory development, and that this is achieved through a systematic and consistent approach that assures linkages between stated equity objectives, regulatory analyses, selection of policy options, and the design of compliance and enforcement activities.

Molecules, Vol. 16, Pages 5207-5227: Synthesis and Characterization of (Z)-5-Arylmethylidene-rhodanines with Photosynthesis-Inhibiting Properties

Posted: 22 Jun 2011 12:00 AM PDT

A series of rhodanine derivatives was prepared. The synthetic approach, analytical and spectroscopic data of all synthesized compounds are presented. Lipophilicity of all the discussed rhodanine derivatives was analyzed using the RP-HPLC method. The compounds were tested for their ability to inhibit photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts and reduce chlorophyll content in freshwater alga Chlorella vulgaris. Structure-activity relationships between the chemical structure, physical properties and biological activities of the evaluated compounds are discussed. For majority of the tested compounds the lipophilicity of the compound and not electronic properties of the R1 substituent were decisive for PET-inhibiting activity. The most potent PET inhibitor was (5Z)-5-(4-bromobenzylidene)-2-thioxo-1,3-thiazolidin-4-one (IC50 = 3.0 μmol/L) and the highest antialgal activity was exhibited by (5Z)-5-(4-chlorobenzylidene)-2-thioxo-1,3-thiazolidin-4-one (IC50 = 1.3 μmol/L).

IJERPH, Vol. 8, Pages 2352-2365: Investigation of Spatial and Temporal Trends in Water Quality in Daya Bay, South China Sea

Posted: 22 Jun 2011 12:00 AM PDT

The objective is to identify the spatial and temporal variability of the hydrochemical quality of the water column in a subtropical coastal system, Daya Bay, China. Water samples were collected in four seasons at 12 monitoring sites. The Southeast Asian monsoons, northeasterly from October to the next April and southwesterly from May to September have also an important influence on water quality in Daya Bay. In the spatial pattern, two groups have been identified, with the help of multidimensional scaling analysis and cluster analysis. Cluster I consisted of the sites S3, S8, S10 and S11 in the west and north coastal parts of Daya Bay. Cluster I is mainly related to anthropogenic activities such as fish-farming. Cluster II consisted of the rest of the stations in the center, east and south parts of Daya Bay. Cluster II is mainly related to seawater exchange from South China Sea.

Molecules, Vol. 16, Pages 5182-5193: Synthesis of Some Novel Pyrazolo[1,5-a]pyrimidine Derivatives and Their Application as Disperse Dyes

Posted: 22 Jun 2011 12:00 AM PDT

A series of novel monoazo-disperse dyes containing pyrazolo[1,5-a]pyrimidine structures were synthesized starting with the coupling reaction between ethyl cyanoacetate and 4-hydroxybenzenediazonium chloride, followed by treatment of the resulting hydrazone product with hydrazine hydrate. The pyrazolohydrazone 6 is then treated with either 2,4-pentandione and enaminonitrile or aryl-substituted enaminoketones to give the target pyrazolo[1,5-a]pyrimidine dyes 7 and 15a-d. Structural assignments to the dyes were made using NMR spectroscopic methods. A new high temperature method, using microwave heating, was employed to apply these dyes to polyester fibers. Most of the dyed fabrics tested displayed moderate light fastness and excellent washing fastness properties.

Marine Drugs, Vol. 9, Pages 1133-1141: Swinholide J, a Potent Cytotoxin from the Marine Sponge Theonella swinhoei

Posted: 22 Jun 2011 12:00 AM PDT

In our ongoing search for new pharmacologically active leads from Solomon organisms, we have examined the sponge Theonella swinhoei. Herein we report the isolation and structure elucidation of swinholide A (1) and one new macrolide, swinholide J (2). Swinholide J is an unprecedented asymmetric 44-membered dilactone with an epoxide functionality in half of the molecule. The structural determination was based on extensive interpretation of high-field NMR spectra and HRESIMS data. Swinholide J displayed potent in vitro cytotoxicity against KB cells (human nasopharynx cancer) with an IC50 value of 6 nM.

IJERPH, Vol. 8, Pages 2331-2351: Prevalence of Children with Severe Fetal Alcohol Spectrum Disorders in Communities Near Rome, Italy: New Estimated Rates Are Higher than Previous Estimates

Posted: 22 Jun 2011 12:00 AM PDT

Objective: To determine the population-based epidemiology of fetal alcohol syndrome (FAS) and other fetal alcohol spectrum disorders (FASD) in towns representative of the general population of central Italy. Methods: Slightly revised U.S. Institute of Medicine diagnostic methods were used among children in randomly-selected schools near Rome. Consented first grade children (n = 976) were screened in Tier I for height, weight, or head circumference and all children
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