Games |
- Table Top Racing - Screenshots
- Tennis in the Face
- HyperCube 10.80 - Analyse/display multi- and hyperspectral imagery.. (Free)
- Marine Drugs, Vol. 11, Pages 332-349: Iodinin (1,6-Dihydroxyphenazine 5,10-Dioxide) from Streptosporangium sp. Induces Apoptosis Selectively in Myeloid Leukemia Cell Lines and Patient Cells
- Materials, Vol. 6, Pages 410-420: Effect of Thermal Treatment of Veneer on Formaldehyde Emission of Poplar Plywood
- Materials, Vol. 6, Pages 392-409: Mechanism of Catalytic Water Oxidation by the Ruthenium Blue Dimer Catalyst: Comparative Study in D2O versus H2O
- Metabolites, Vol. 3, Pages 47-71: Characterisation of the Metabolites of 1,8-Cineole Transferred into Human Milk: Concentrations and Ratio of Enantiomers
- Crystals, Vol. 3, Pages 49-78: Indirect Exchange and Ruderman–Kittel–Kasuya–Yosida (RKKY) Interactions in Magnetically-Doped Graphene
- Applied Sciences, Vol. 3, Pages 70-93: Direct Electron Acceleration with Radially Polarized Laser Beams
- IJERPH, Vol. 10, Pages 528-540: Childhood Mortality Due to Unintentional Injuries in Japan, 2000–2009
- Surge - Screenshots
- iBeeZz 2.7.8 - Schedules daily sleep and wake times for your Mac.. (Shareware)
- Scrapbook 1.3 - Copy and store multiple clips.. (Commercial)
- IJGI, Vol. 2, Pages 1-26: A Bottom-Up Approach for Automatically Grouping Sensor Data Layers by their Observed Property
- Minerals, Vol. 3, Pages 49-58: A New Direction for Biomining: Extraction of Metals by Reductive Dissolution of Oxidized Ores
- Metabolites, Vol. 3, Pages 33-46: Metabonomic Response to Milk Proteins after a Single Bout of Heavy Resistance Exercise Elucidated by 1H Nuclear Magnetic Resonance Spectroscopy
- Games, Vol. 4, Pages 38-49: Nash Implementation in an Allocation Problem with Single-Dipped Preferences
- Nutrients, Vol. 5, Pages 328-339: Food Safety Attitudes in College Students: A Structural Equation Modeling Analysis of a Conceptual Model
- Toxins, Vol. 5, Pages 224-248: Disruption of the Putative Vascular Leak Peptide Sequence in the Stabilized Ricin Vaccine Candidate RTA1-33/44-198
- Sustainability, Vol. 5, Pages 432-439: Growth Is the Problem; Equality Is the Solution
| Table Top Racing - Screenshots Posted: 30 Jan 2013 03:41 AM PST Players can also win coins, upgrade vehicles, unlock new cars, expand their weapons cabinet in a bid to blast their way to the front of the grid. Simple, responsive controls make 'Table Top Racing' instantly playable with super smooth frame rates on all supported devices delivering a stunning racing game experience. Table Top Racing features: - 8 Incredibly detailed, beautifully rendered race circuits - Intense 4 Player multi-player battles over Game Centre. 6 Players over Wifi or Bluetooth. - Apple Gamecentre Leaderboards - Global player ranking and Per Track Lap times - Multiple Game Centre Achievements - 10 Awesome vehicles to race with Tuning, Wheel and Paint shops - 4 Multi-event Championships to conquer with Season Finales - 6 Gameplay modes - Hot-Lap, Speed-Trial, Combat, Pure Race, Pursuit, Eliminator - Ultra-smooth 60 frames per second console quality gameplay - Crisp native Retina graphics (on applicable devices) - Beautiful real-time lighting effects on iPhone 5, iPad 4th Gen, iPod 5, iPad 2 and iPad Mini |
| Posted: 29 Jan 2013 04:06 PM PST Platform: iOS —  Ever had a tennis ball delivered to your face? Not in the gentle way your local postal service worker might deliver a package (*snicker*), the kind of delivery where a professional aims for your head and gives it a good shot? We're glad you answered "no", because if it were true, you might end up like the villains in Tennis in the Face, a game of precision physics from 10tons. A little bit of aiming and a whole lot of ricocheting can go a long way. It's time to take down the corporate machine! Tagged as: 10tons, arcade, game, ios, ipad, iphone, mobile, physics, ragdoll, rating-y, tablet |
| HyperCube 10.80 - Analyse/display multi- and hyperspectral imagery.. (Free) Posted: 30 Jan 2013 03:22 AM PST HyperCube is an application specifically directed to the analysis and display of multi- and hyperspectral imagery. This includes the static and dynamic display of the image cube and the generation of spectral classifications using both imagery and spectral libraries. In addition, HyperCube contains functions to filter, warp, mosaic, reformat, calibrate, combine, photogrammetrically project and to perform arithmetic on imagery and data. Version 10.80:
OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 30 Jan 2013 12:00 AM PST Despite recent improvement in therapy, acute myeloid leukemia (AML) is still associated with high lethality. In the presented study, we analyzed the bioactive compound iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from a marine actinomycetes bacterium for the ability to induce cell death in a range of cell types. Iodinin showed selective toxicity to AML and acute promyelocytic (APL) leukemia cells, with EC50 values for cell death up to 40 times lower for leukemia cells when compared with normal cells. Iodinin also successfully induced cell death in patient-derived leukemia cells or cell lines with features associated with poor prognostic such as FLT3 internal tandem duplications or mutated/deficient p53. The cell death had typical apoptotic morphology, and activation of apoptotic signaling proteins like caspase-3. Molecular modeling suggested that iodinin could intercalate between bases in the DNA in a way similar to the anti-cancer drug daunorubicin (DNR), causing DNA-strand breaks. Iodinin induced apoptosis in several therapy-resistant AML-patient blasts, but to a low degree in peripheral blood leukocytes, and in contrast to DNR, not in rat cardiomyoblasts. The low activity towards normal cell types that are usually affected by anti-leukemia therapy suggests that iodinin and related compounds represent promising structures in the development of anti-cancer therapy. |
| Posted: 30 Jan 2013 12:00 AM PST A large amount of poplar plywood is now being imported into Japan from China, and as a result, formaldehyde emitted from this plywood represents an undesirable chemical that must be controlled using a chemical catching agent. The aim of this study is to find an approach to reduce the formaldehyde emission of poplar plywood using thermal treatment without employing any chemicals. The experimental results obtained show that heating veneer sheets in the temperature range of 150 °C to 170 °C effectively reduced the formaldehyde emission of plywood, without diminishing the mechanical properties of the veneer. By applying Langmuir’s theory and Hailwood-Horrobin theory to the adsorption isotherm obtained in this study, the relationship between the formaldehyde emission of plywood and the adsorption properties of veneer as a material is discussed. When veneer sheets were heated in the temperature range of 150 °C to 170 °C, the amount of hydrated water (monomolecular layer) decreased slightly and that of dissolved water (polymolecular layer) did not change. It is hypothesized that the formaldehyde emission of plywood is related to the condition of the adsorption site of the wood. |
| Posted: 30 Jan 2013 12:00 AM PST Water oxidation is critically important for the development of energy solutions based on the concept of artificial photosynthesis. In order to gain deeper insight into the mechanism of water oxidation, the catalytic cycle for the first designed water oxidation catalyst, cis,cis-[(bpy)2(H2O)RuIIIORuIII(OH2)(bpy)2]4+ (bpy is 2,2-bipyridine) known as the blue dimer (BD), is monitored in D2O by combined application of stopped flow UV-Vis, electron paramagnetic resonance (EPR) and resonance Raman spectroscopy on freeze quenched samples. The results of these studies show that the rate of formation of BD[4,5] by Ce(IV) oxidation of BD[3,4] (numbers in square bracket denote oxidation states of the ruthenium (Ru) centers) in 0.1 M HNO3, as well as further oxidation of BD[4,5] are slower in D2O by 2.1–2.5. Ce(IV) oxidation of BD[4,5] and reaction with H2O result in formation of an intermediate, BD[3,4]′, which builds up in reaction mixtures on the minute time scale. Combined results under the conditions of these experiments at pH 1 indicate that oxidation of BD[3,4]′ is a rate limiting step in water oxidation with the BD catalyst. |
| Posted: 30 Jan 2013 12:00 AM PST 1,8-Cineole is a widely distributed odorant that also shows physiological effects, but whose human metabolism has hitherto not been extensively investigated. The aim of the present study was, thus, to characterise the metabolites of 1,8-cineole, identified previously in human milk, after the oral intake of 100 mg of this substance. Special emphasis was placed on the enantiomeric composition of the metabolites since these data may provide important insights into potential biotransformation pathways, as well as potential biological activities of these substances, for example on the breastfed child. The volatile fraction of the human milk samples was therefore isolated via Solvent Assisted Flavour Evaporation (SAFE) and subjected to gas chromatography-mass spectrometry (GC-MS). The absolute concentrations of each metabolite were determined by matrix calibration with an internal standard, and the ratios of enantiomers were analysed on chiral capillaries. The concentrations varied over a broad range, from traces in the upper ng/kg region up to 40 µg/kg milk, with the exception of the main metabolite α2-hydroxy-1,8-cineole that showed concentrations of 100–250 µg/kg. Also, large inter- and intra-individual variations were recorded for the enantiomers, with nearly enantiomerically pure α2-hydroxy- and 3-oxo-1,8-cineole, while all other metabolites showed ratios of ~30:70 to 80:20. |
| Posted: 30 Jan 2013 12:00 AM PST Magnetically-doped graphene systems are potential candidates for application in future spintronic devices. A key step is to understand the pairwise interactions between magnetic impurities embedded in graphene that are mediated by the graphene conduction electrons. A large number of studies have been undertaken to investigate the indirect exchange, or RKKY (Ruderman-Kittel-Kasuya-Yosida), interactions in graphene. Many of these studies report a decay rate faster than expected for a two-dimensional material and the absence of the usual distance dependent oscillations. In this review we summarize the techniques used to calculate the interaction and present the key results obtained to date. The effects of more detailed parameterisations of the magnetic impurities and graphene host are considered, as are results obtained from ab initio calculations. Since the fast decay of the interaction presents an obstacle to spintronic applications, we focus in particular on the possibility of augmenting the interaction range by a number of methods including doping, spin precession and the application of strain. |
| Posted: 30 Jan 2013 12:00 AM PST In the past years, there has been a growing interest in innovative applications of radially polarized laser beams. Among them, the particular field of laser-driven electron acceleration has received much attention. Recent developments in high-power infrared laser sources at the INRS Advanced Laser Light Source (Varennes, Qc, Canada) allowed the experimental observation of a quasi-monoenergetic 23-keV electron beam produced by a radially polarized laser pulse tightly focused into a low density gas. Theoretical analyses suggest that the production of collimated attosecond electron pulses is within reach of the actual technology. Such an ultrashort electron pulse source would be a unique tool for fundamental and applied research. In this paper, we propose an overview of this emerging topic and expose some of the challenges to meet in the future. |
| Posted: 30 Jan 2013 12:00 AM PST This study examined deaths due to unintentional injuries among children in Japan to identify the age groups and sexes at most risk, and the types of injuries, so that effective forms of targeted intervention can be devised. Among children aged 0–14 years, deaths whose underlying causes had been classified under code V01-X59 of the ICD-10 were defined as deaths of children caused by unintentional injuries. Using data from the Vital Statistics 2000–2009 for analysis, we examined the changes in mortality and trends in terms of sex, age, and cause of death. Mortality decreased by 46.2%, from 933 in 2000 to 502 in 2009. The mortality rate among children aged 1–4 years decreased by almost half. The total number of deaths during this decade was 7,362 (boys: 4,690, girls: 2,672). Among the causes of death, the majority were due to “transport accidents”, followed by “other accidental threats to breathing”, and “accidental drowning and submersion”. The characteristics observed in terms of sex, age, and cause of death—that is, deaths from suffocation among infants aged less than 1 year, drowning deaths among boys, and transport accidents involving pedestrians and cyclists—must be addressed as targets for future intervention. |
| Posted: 30 Jan 2013 03:06 AM PST |
| iBeeZz 2.7.8 - Schedules daily sleep and wake times for your Mac.. (Shareware) Posted: 30 Jan 2013 03:09 AM PST  iBeeZz allows you to setup when your Mac must sleep, wake up, shutdown, startup, restart, etc. Execute any AppleScripts, open any files, launch any applications. No matter what you ask iBeeZz to load, from documents to applications to compiled AppleScripts, they will be launched, opened or executed at the right moment. Wake up with iTunes.
Version 2.7.8 :
OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Scrapbook 1.3 - Copy and store multiple clips.. (Commercial) Posted: 30 Jan 2013 03:03 AM PST  Scrapbook is an innovative Clipboard, which enables you to store more than one item for future use. All of your clip entries will remain even if you restart your Computer. Scrapbook offers the advantage of a discreet and simple interface. Moreover, you can use snippets, predefined tools and self configurable JavaScript filters. Main-Features:
We hope you like Scrapbook. If you have questions, problems or wishes please feel free to send us an e-mail. Version 1.3: Note: Because of Apple's Sandboxing we had to remove some parts of Scrapbook! We are very sorry about this :(
OS X 10.6.6 or later Download Now |
| Posted: 30 Jan 2013 12:00 AM PST The Sensor Web is a growing phenomenon where an increasing number of sensors are collecting data in the physical world, to be made available over the Internet. To help realize the Sensor Web, the Open Geospatial Consortium (OGC) has developed open standards to standardize the communication protocols for sharing sensor data. Spatial Data Infrastructures (SDIs) are systems that have been developed to access, process, and visualize geospatial data from heterogeneous sources, and SDIs can be designed specifically for the Sensor Web. However, there are problems with interoperability associated with a lack of standardized naming, even with data collected using the same open standard. The objective of this research is to automatically group similar sensor data layers. We propose a methodology to automatically group similar sensor data layers based on the phenomenon they measure. Our methodology is based on a unique bottom-up approach that uses text processing, approximate string matching, and semantic string matching of data layers. We use WordNet as a lexical database to compute word pair similarities and derive a set-based dissimilarity function using those scores. Two approaches are taken to group data layers: mapping is defined between all the data layers, and clustering is performed to group similar data layers. We evaluate the results of our methodology. |
| Posted: 30 Jan 2013 12:00 AM PST Biomining, the biotechnology that uses microorganisms to extract metals from ores and concentrates, is currently used exclusively for processing reduced ores and mine wastes. Metals of economic value also occur extensively in oxidized ores, such as nickel laterites. While these are not amenable to oxidative dissolution, the ferric iron minerals they contain can, in theory, be disrupted by iron reduction, causing associated metals to be released. We have harnessed the ability of the facultatively anaerobic, acidophilic bacterium Acidithiobacillus ferroooxidans to couple the oxidation of elemental sulphur to the reduction of ferric iron in the goethite fraction of a limonitic nickel ore at 30 °C. Nickel and other metals (Co, Cr and Mn) were effectively solubilised and maintained in solution due to the low pH (1.8) of the leach liquor. The results highlight the potential for the bioprocessing of oxidized, iron-rich ores using an approach that is energy-saving and environmentally-benign compared with metallurgical processes currently applied to the extraction of Ni from lateritic ores. |
| Posted: 30 Jan 2013 12:00 AM PST In the present study, proton NMR-based metabonomics was applied on femoral arterial plasma samples collected from young male subjects (milk protein n = 12 in a crossover design; non-caloric control n = 8) at different time intervals (70, 220, 370 min) after heavy resistance training and intake of either a whey or calcium caseinate protein drink in order to elucidate the impact of the protein source on post-exercise metabolism, which is important for muscle hypertrophy. Dynamic changes in the post-exercise plasma metabolite profile consisted of fluctuations in alanine, beta-hydroxybutyrate, branched amino acids, creatine, glucose, glutamine, glutamate, histidine, lipids and tyrosine. In comparison with the intake of a non-caloric drink, the same pattern of changes in low-molecular weight plasma metabolites was found for both whey and caseinate intake. However, the study indicated that whey and caseinate protein intake had a different impact on low-density and very-low-density lipoproteins present in the blood, which may be ascribed to different effects of the two protein sources on the mobilization of lipid resources during energy deficiency. In conclusion, no difference in the effects on low-molecular weight metabolites as measured by proton NMR-based metabonomics was found between the two protein sources. |
| Posted: 30 Jan 2013 12:00 AM PST In this paper, we study the Nash implementation in an allocation problem with single-dipped preferences. We show that, with at least three agents, Maskin monotonicity is necessary and sufficient for implementation. We examine the implementability of various social choice correspondences (SCCs) in this environment, and prove that some well-known SCCs are Maskin monotonic ( but they do not satisfy no-veto power) and hence Nash implementable. |
| Posted: 30 Jan 2013 12:00 AM PST College students are one of the most at-risk population groups for food poisoning, due to risky food safety behaviors. Using the Likert Scale, undergraduate students were asked to participate in a Food Safety Survey which was completed by 499 students ages 18–25. Data was analyzed using SPSS and AMOS statistical software. Four conceptual definitions regarding food safety were defined as: general food safety, bacterial food safety, produce food safety, and politics associated with food safety. Knowledge seems to be an important factor in shaping students attitudes regarding general and bacterial safety. Ethnicity plays a role in how people view the politics of food safety, and the safety of organic foods. |
| Posted: 30 Jan 2013 12:00 AM PST Vitetta and colleagues identified and characterized a putative vascular leak peptide (VLP) consensus sequence in recombinant ricin toxin A-chain (RTA) that contributed to dose-limiting human toxicity when RTA was administered intravenously in large quantities during chemotherapy. We disrupted this potentially toxic site within the more stable RTA1-33/44-198 vaccine immunogen and determined the impact of these mutations on protein stability, structure and protective immunogenicity using an experimental intranasal ricin challenge model in BALB/c mice to determine if the mutations were compatible. Single amino acid substitutions at the positions corresponding with RTA D75 (to A, or N) and V76 (to I, or M) had minor effects on the apparent protein melting temperature of RTA1-33/44-198 but all four variants retained greater apparent stability than the parent RTA. Moreover, each VLP(−) variant tested provided protection comparable with that of RTA1-33/44-198 against supralethal intranasal ricin challenge as judged by animal survival and several biomarkers. To understand better how VLP substitutions and mutations near the VLP site impact epitope structure, we introduced a previously described thermal stabilizing disulfide bond (R48C/T77C) along with the D75N or V76I substitutions in RTA1-33/44-198. The D75N mutation was compatible with the adjacent stabilizing R48C/T77C disulfide bond and the Tm was unaffected, whereas the V76I mutation was less compatible with the adjacent disulfide bond involving C77. A crystal structure of the RTA1-33/44-198 R48C/T77C/D75N variant showed that the structural integrity of the immunogen was largely conserved and that a stable immunogen could be produced from E. coli. We conclude that it is feasible to disrupt the VLP site in RTA1-33/44-198 with little or no impact on apparent protein stability or protective efficacy in mice and such variants can be stabilized further by introduction of a disulfide bond. |
| Sustainability, Vol. 5, Pages 432-439: Growth Is the Problem; Equality Is the Solution Posted: 30 Jan 2013 12:00 AM PST While the world economy has become more efficient in one sense, i.e., ecological damage per dollar's worth of economic output, growth in human population size and per-capita production and consumption of goods and services have together far outpaced these gains. Grievous environmental harm has resulted, whether measured in terms of human sustainability through the ecological footprint, or non-human welfare through such indicators as the living planet index and the number of threatened species. Many have therefore called for a reorientation of economic priorities away from growth, and toward equality as a more environmentally-friendly way to enhance human well-being. In this paper, I test the merits of this proposal through analysis of a few key national economic and ecological variables across time and space. The results confirm the hypothesis that equality does far less harm to ecosystems than growth does. In fact, equality seems to benefit one crucial aspect of environmental quality, namely biological diversity. |
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