понедельник, 19 сентября 2011 г.

Games

Games


Molecules, Vol. 16, Pages 8062-8075: Effects of St John's Wort (Hypericum perforatum L.) Extracts on Epileptogenesis

Posted: 19 Sep 2011 12:00 AM PDT

The purpose of this study was to investigate the effects of treatment with water, n-butanol and ether extracts of Hypercom perforatum L. on epileptogenesis in rabbits. Animals from the control group received solvent-ethanol, and the kindling model of epilepsy was used. Epileptic focus was induced in Chinchilla rabbits by stimulation of the hippocampus. The following parameters were determined: the minimum current strength necessary to induce after-discharge (AD) – discharges appearing after cessation of stimulation; AD duration; the number of stimulations necessary to induce spontaneous kindling; and the latency time for the development of full kindling. The results obtained indicate that epileptogenesis is influenced by Hypericum perforatum L. extract treatment. Animals treated with an ether extract of Hypericum perforatum L. required significantly weaker minimum current strengths for the development of epileptogenic focus, and displayed longer AD times, while the number of electro-stimulations necessary for full kindling was less. In contrast, animals treated with water and n-butanol extracts required increased electro-stimulations for the development of epileptic discharge, and displayed shortened AD durations versus controls.

Presence 2.7.1 - Access files on your Mac from any web browser, iPhone or iPad.. (Shareware)

Posted: 19 Sep 2011 03:14 AM PDT



Presence... (formerly known as FarFinder) Access your Mac's files securely from anywhere in the world by web browser, iPhone and iPad, via a Finder-like interface and your own URL. Plus share files and folders with others, instantly and with no uploading.

Cloud services make some of your files available, and copy them to someone else's server. Presence puts your whole Mac in the cloud, and doesn't copy your files anywhere. Access to everything, securely - this is how the cloud should be.

You can access your Mac's files from any computer: Mac, Windows or Linux, using only a web browser.

Even better, the iPhone and iPad app means you really do have access to your Mac anytime, anywhere.

Presence also makes it easy to get files to other people. Big files are no problem, even if they're too big to email - with Presence, you just send a link. You can share multiple files and folders in the same link, and shares are password-protected if you like. And, you can do it from anywhere.

Presence provides the most Mac-like multi-platform remote access available, with an interface that looks very like your Mac. You can browse folders, download and upload files, and more - all from within any web browser or the iOS app.

You also have the full power of Spotlight searches to find files quickly, and like on the Mac, Finder searches let you be more specific about where to look.

Presence also lets you keep an eye on what's going on at home by taking a photo through your Mac's built-in camera.

Try Presence and find out why Macworld UK described it as "Better Than Back to My Mac".

Version 2.7.1

  • Fixed event logging. See More Options - View Event Log to see a record of logins and share accesses.
  • More reliable Growl support: logins and share accesses are now Growled reliably.
  • Fixed a bug that caused the "starting up" message to be displayed indefinitely under certain circumstances.


Mac OS X 10.6 or later.

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Webjimbo 2.7.1 - Web interface for Yojimbo.. (Shareware)

Posted: 19 Sep 2011 03:31 AM PDT



Webjimbo is a web interface for Bare Bones Software's Yojimbo. It lets you view and edit your Yojimbo data from your iPhone or any computer with an internet connection and a web browser.

Version 2.7.1
  • Fixed event logging. See More Options - View Event Log to see a record of logins.
  • More reliable Growl support: logins are now Growled reliably.
  • Fixed a bug that caused the "starting up" message to be displayed indefinitely under certain circumstances.


  • Mac OS X 10.6 or later
  • Yojimbo 3 or later
  • Modern Web browser.
  • Your Mac running Yojimbo must be logged in and connected to the internet.


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Star PDF Watermark 1.4.0 - Batch watermark PDF files.. (Free)

Posted: 19 Sep 2011 03:03 AM PDT



Star PDF Watermark is a batch PDF watermarking tool for Mac, you can fast add text or image watermark to Acrobat PDF file, such as add signatures, company name or company logo to protect you PDF file copyright. With PDF watermarking software free version, you could add TEXT water mark for your PDF files, With PDF watermark software purchased version, you can add not only TEXT watermark, but also IMAGE watermark to your PDF document.

Version 1.3.0:
  • Improvement: Add support email on register panel; Improve watermark performance when create new watermark template.


Mac OS X 10.4 or later.

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iPack 1.80 - Full-featured compressed archives manager.. (Commercial)

Posted: 19 Sep 2011 03:10 AM PDT



iPack is a full-featured compressed archives manager.

Highlights:

  • Compress 7z, zip, jar, and rar archives
  • Decompress 7z, zip, jar, rar, cab, iso, arj, gz and bz2 archives
  • NEW! Integration with Finder: compress files in Finder directly
  • Quick preview files without extracting them
  • Conversion from 7z/zip/rar/gz/bz2 to 7z/zip/rar formats
  • Quick archive decompression by dragging files to the drop basket
  • NEW! Take advantage of the power of multicore CPU: iPack works at least 100% faster when you have 2011 Macs.
  • Superb speed benefited by 64-bit computing power
  • Full support of international file names (especially Chinese, Japanese and Korean file names created by old archivers)
  • Full support of password-protected archives
  • Full support of drag and drop
  • Multi-volumed archives support
  • Search file names inside archives with fancy highlight effect
If you have no need for password protection, download the free iPackr.



Version 1.80:
  • New: iPack is integrated to Finder. Now you can select files or folders in Finder then compress them with iPack from Services of the contextual menu (right-click the mouse and you will see it).
  • New: automatically set archive file name of new archives
  • Fixed: "Password for files and file names" causes failure on zip creation.


Mac OS X 10.6 or later

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Molecules, Vol. 16, Pages 8053-8061: A Short Synthesis of Bisabolane Sesquiterpenes

Posted: 19 Sep 2011 12:00 AM PDT

A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes.

Molecules, Vol. 16, Pages 8041-8052: Intramolecular C-H···O Hydrogen Bonding in 1,4-Dihydropyridine Derivatives

Posted: 19 Sep 2011 12:00 AM PDT

The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH···O intramolecular hydrogen bond is one of the factors amplifying the chemical shift differences in the 1H-NMR spectra.

Kevin Kidney’s Hatbox Ghost

Posted: 19 Sep 2011 03:02 AM PDT


Kevin and Jody Kidney created this one-off maquette of Colin Campbell's 1969 illustration depicting The Hatbox Ghost, a very short-lived illusion that was once part of the Disneyland Haunted Mansion. They're bringing it to the Walt Disney World 40th birthday celebration on Sept 30/Oct 1 (gutted to be missing this!)
As far as we know, we've never seen a three-dimensional figure based on Campbell's Haunted Mansion illustrations, so this may very well be the first. Our 8-1/4" tall ghost was cast from my sculpture and then hand-painted by Jody in Campbell's illustrative style, with "hair" fibers added on as a final touch. The maquette is displayed on a wooden base made of antique weathered barn wood, under a glass bell jar. When viewed through the wavy glass, the figure takes on a mildly distorted appearance that makes him even more ghostly.
Ghoulish Delight

Star Watermark for Mac Ultimate 1.1.0 - Batch add multi text and image layer watermarks to photos.. (Shareware)

Posted: 19 Sep 2011 02:58 AM PDT



Star Watermark for Mac Ultimate is a batch photo watermark tool. The Unique function of Star Watermark for Mac Ultimate Version is you could batch add multi layers watermark to photos, you can easily batch add multi text layers and image layers watermark to your photos at a time! Star Watermark for Mac Ultimate is an essential tool for anyone with a digital camera, professionals and beginners or graphic artist on Mac OS X. Click here to see a detailed introduction.

Version 1.1.0:
  • New: Add gradient text function for watermarking.
  • Improvement: Add support email on register panel; Improve watermark performance when create new watermark layer.


Mac OS X 10.5 or later

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Tracking down a con artist with PACER

Posted: 19 Sep 2011 02:54 AM PDT

On Saturday, I posted about Popehat's "Anatomy of a Scam Investigation," in which Ken, a former federal prosecutor, is documenting his work to run down a con-artist who tried to rip him off with the "toner scam." Yesterday, Ken posted a new installment in the series in which he documents the use of PACER, the database of court records, to research crooks. It's gripping stuff.

King of Dragon Pass

Posted: 18 Sep 2011 07:10 PM PDT

[Platform: Mobile (iPhone, iPod Touch)] One part strategy, one part text-driven choose your own story adventure, King of Dragon Pass is exactly the game you want on your mobile device. Ported to iOS from the original PC/Mac release of 1999, this storytelling experience is rich in its own history and affords you a vast amount of control over what happens within. Wage war, explore the land, trade with your neighbors, manage your tribe, and read pages upon pages of text explicating the world you're actively participating in. It's great to see a title like this brought back for a new wave of gamers to play, and it works quite well on the iPhone platform.

How to get help, give help

Posted: 19 Sep 2011 12:54 AM PDT

People living in the Sayre, Athens and Waverly school districts should call The Bridge of Penn York Valley Churches to learn how to receive donated funds, clothing and furniture.

Mobile Monday

Posted: 18 Sep 2011 06:38 PM PDT

[Platform: Mobile (iPhone, iPod Touch)] Wacky, serious, filled with animals, containing goat kisses, and populated by sentient glops of furry... whatever. It's not a Mobile Monday if you don't reach for the disinfectant spray!

1Password 3.8.6 - Powerful password manager; integrates with Web browsers and more.. (Shareware)

Posted: 18 Sep 2011 08:59 PM PDT



1Password is a password manager that uniquely brings you both security and convenience. It is the only program that provides anti-phishing protection and goes beyond password management by adding web form filling and automatic strong password generation. All your confidential information, including passwords, identities, and credit cards, is kept secure in one secure place using a highly encrypted keychain.

1Password fully supports most web browsers, including Safari, OmniWeb, DEVONagent, Firefox, Flock, Fluid, and NetNewsWire. All browser extensions share the data stored in the keychain which means you never need to manually copy your passwords between browsers or from the password manager to a browser ever again!

1Password has received numerous awards, including 4.5 mice from Macworld magazine, MacLife Editors pick, and was the Pick of Week on MacBreak Weekly by both Leo Laporte and Merlin Mann.

1Password also has a companion iPhone/iPod touch application available in iTunes App Store.



Version 3.8.6:
  • New: Added Full Screen support in Lion.
  • Changed: Improved performance of keyboard event handling in Google Chrome.
  • Changed: Updated Go & Fill on Snow Leopard to support new Firefox and Chrome extensions.
  • Changed: Updated Autolock based on computer activity to attempt to work around issue where 1Password would constantly lock during remote screen sharing.
  • Changed: Many updates to Diagnostics Report to report information about Mac App Store versions of 1Password and several other scenarios.
  • Fixed: Fixed wrong icon used in Go menu.
  • Fixed: Improved reliability of data exchange between browser extensions and 1Password Helper.
  • Fixed: Fixed problem where 1PasswordAgent could crash when communicating with browser extensions.


  • Mac OS X 10.6 or later
  • Most major browsers supported


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FinderPop 2.4 - A classic Mac utility, now a prefpane for OS X.. (Free)

Posted: 18 Sep 2011 08:59 PM PDT



FinderPop is a Universal preference pane that extends OS X's contextual menus using a FinderPop Items folder much as the Apple Menu Items folder used to do for the Apple menu.

It has other features too:

  • Control-free popup in the Finder - handy for those with one-button mice.
  • A launcher that takes up zero screen real estate, merely a click on any blank area of menubar away,
  • A handy filesystem browser, allowing quick and easy access to files and disks in the Finder,
  • A Processes menu (Command-click a blank menubar area.)
  • Fast access to 'Where's that dratted file I had on the Desktop?' (Shift-Click a blank menubar area.)
  • A comprehensive collection of vaguely beer-related aphorisms in the Aboutbox.

Please use the FinderPop Help button in the preference pane; there are many features in FP that are not immediately obvious. I'm working on it :-) The FAQ in the Help is also worth a read. Most UI elements have fairly comprehensive help tags, so just hover the mouse over something if you're not sure. The manual is also available online. Also note the FinderPop Support Forum.

Version 2.4:

  • Mac OS X 10.7 compatibility.


Mac OS X 10.4 or later

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TrailRunner 3.7.660 - Route planning for hiking, biking, more.. (Shareware)

Posted: 18 Sep 2011 08:59 PM PDT



TrailRunner is the perfect companion for runners, bikers, hikers, and all people wandering under the sky. Plan routes on a geographical map. Import GPS or workout recordings and journalize your activities in a diary.

Features:

  • View Maps and Elevation Data from Internet mapping services like USGS topo maps.
  • Import GPS Recordings from Trails, iTrail and 321Run for iPhone.
  • Import workouts from the Nike + iPod Sport Kit.
  • Import tracks and workouts from GPS fitness devices like the Garmin ForeRunner or Garmin Edge.
  • Import/Export TCX, GPX, and KML files.
  • Describe favorite tracks and rate them with iTunes stars.
  • Plan routes interactively or automatically for a given distance.
  • Export route directions onto your iPod.
  • Journalize workouts in a diary, see your progress in a history chart.
  • Publish a WebLog to MobileMe.


Version 3.7.660: Release notes were unavailable when this listing was updated.

Mac OS X 10.6 or later

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Transmission 2.40b1 - Popular BitTorrent client.. (Free)

Posted: 18 Sep 2011 08:59 PM PDT



Transmission is a fast, easy, and free multi-platform BitTorrent client.

Transmission sets initial preferences so things "Just Work", while advanced features like watch directories, bad peer blocking, and the web interface can be configured with just a few clicks. Macworld put it this way: "It's fast, it's extremely lightweight, and - even though it's available for a variety of platforms - it behaves just as you'd expect a Mac program to."

Transmission supports full encryption, file selection, a web-based interface, groups, peer exchange, automatic port forwarding, webseeds, watch directories, tracker editing, global and per-torrent speed limits, and more.

Its code is freely available online and is licensed under either the GNU Public License v2 or the MIT License. The development team welcomes anyone who is interested in contributing code, documentation, translations, or other help.



Version 2.40b1:
  • Mac OS X 10.7: Use popovers for the global and per-torrent action menus
  • Mac OS X 10.7: Animations in the inspector's file list and the message window
  • Sort transfers by size
  • No longer keep track of recently opened torrent files
  • Improved webseed support
  • Fix crash when removing a magnetized transfer
  • Fix adding transfers over RPC when a subfolder does not exist
  • Minor fixes, interface tweaks, and behavior adjustments
Web Client:
  • Speed improvements
  • Add filtering by tracker
  • Allow preference changes on mobile devices
  • Allow compact view on mobile devices
  • Stop ratio functionality
  • Queue functionality
  • Compact view interface improvements


Mac OS X 10.5 or later

Download Now

This posting includes an audio/video/photo media file: Download Now

TrailRunner 3.7.660 - Route planning for hiking, biking, more.. (Shareware)

Posted: 18 Sep 2011 08:59 PM PDT



TrailRunner is the perfect companion for runners, bikers, hikers, and all people wandering under the sky. Plan routes on a geographical map. Import GPS or workout recordings and journalize your activities in a diary.

Features:

  • View Maps and Elevation Data from Internet mapping services like USGS topo maps.
  • Import GPS Recordings from Trails, iTrail and 321Run for iPhone.
  • Import workouts from the Nike + iPod Sport Kit.
  • Import tracks and workouts from GPS fitness devices like the Garmin ForeRunner or Garmin Edge.
  • Import/Export TCX, GPX, and KML files.
  • Describe favorite tracks and rate them with iTunes stars.
  • Plan routes interactively or automatically for a given distance.
  • Export route directions onto your iPod.
  • Journalize workouts in a diary, see your progress in a history chart.
  • Publish a WebLog to MobileMe.


Version 3.7.660: Release notes were unavailable when this listing was updated.

Mac OS X 10.6 or later

Download Now

This posting includes an audio/video/photo media file: Download Now

Transmission 2.40b1 - Popular BitTorrent client.. (Free)

Posted: 18 Sep 2011 08:59 PM PDT



Transmission is a fast, easy, and free multi-platform BitTorrent client.

Transmission sets initial preferences so things "Just Work", while advanced features like watch directories, bad peer blocking, and the web interface can be configured with just a few clicks. Macworld put it this way: "It's fast, it's extremely lightweight, and - even though it's available for a variety of platforms - it behaves just as you'd expect a Mac program to."

Transmission supports full encryption, file selection, a web-based interface, groups, peer exchange, automatic port forwarding, webseeds, watch directories, tracker editing, global and per-torrent speed limits, and more.

Its code is freely available online and is licensed under either the GNU Public License v2 or the MIT License. The development team welcomes anyone who is interested in contributing code, documentation, translations, or other help.



Version 2.40b1:
  • Mac OS X 10.7: Use popovers for the global and per-torrent action menus
  • Mac OS X 10.7: Animations in the inspector's file list and the message window
  • Sort transfers by size
  • No longer keep track of recently opened torrent files
  • Improved webseed support
  • Fix crash when removing a magnetized transfer
  • Fix adding transfers over RPC when a subfolder does not exist
  • Minor fixes, interface tweaks, and behavior adjustments
Web Client:
  • Speed improvements
  • Add filtering by tracker
  • Allow preference changes on mobile devices
  • Allow compact view on mobile devices
  • Stop ratio functionality
  • Queue functionality
  • Compact view interface improvements


Mac OS X 10.5 or later

Download Now

This posting includes an audio/video/photo media file: Download Now

Molecules, Vol. 16, Pages 8041-8052: Intramolecular C-H···O Hydrogen Bonding in 1,4-Dihydropyridine Derivatives

Posted: 19 Sep 2011 12:00 AM PDT

The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH···O intramolecular hydrogen bond is one of the factors amplifying the chemical shift differences in the 1H-NMR spectra.

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