Games |
- World Mosaics - Videos and Trailers
- The Book of Unwritten Tales - Videos and Trailers
- Soul Calibur V - Videos and Trailers
- Elmer X 8.5.0 - Create sample ham radio tests, helps pass the FCC tests.. (Shareware)
- Kerio Connect 7.2.4 - Powerful & secure internet mail server.. (Demo)
- Stupid Cupid - Screenshots
- FIFA Street - Screenshots
- Background image by "WhishingOnAsTar!"
- MiJournal 1.0.6 - Feature-rich journaling application.. (Shareware)
- Folder Icon Creator 3.0.2 - Create custom icons for your Mac.. (Shareware)
- Molecules, Vol. 16, Pages 8874-8893: Autotoxicity and Allelopathy of 3,4-Dihydroxyacetophenone Isolated from Picea schrenkiana Needles
- Pharmaceuticals, Vol. 4, Pages 1381-1399: Lipothioureas as Lipids for Gene Transfection: A Review
- IJERPH, Vol. 8, Pages 4082-4101: Prospective Power Calculations for the Four Lab Study of A Multigenerational Reproductive/Developmental Toxicity Rodent Bioassay Using A Complex Mixture of Disinfection By-Products in the Low-Response Region
- Chess Olympiad Tromso 2014
- Mage Gauntlet
- Cancers, Vol. 3, Pages 3957-3971: Emerging Evidence for MicroRNAs as Regulators of Cancer Stem Cells
- Quicksilver 61 - Application launcher and much more.. (Free)
- iFFmpeg 2.7.0 - Convert multimedia files between formats.. (Shareware)
- OnyX 2.4.2b3 - Mac OS X maintenance and optimization tool.. (Free)
- Asia Shippin' Out October 23-29: Battlefield 3
| World Mosaics - Videos and Trailers Posted: 24 Oct 2011 03:38 AM PDT Official gameplay trailer. |
| The Book of Unwritten Tales - Videos and Trailers Posted: 24 Oct 2011 03:55 AM PDT Mummy madness video. |
| Soul Calibur V - Videos and Trailers Posted: 24 Oct 2011 04:12 AM PDT DamPierre theatre trailer. |
| Elmer X 8.5.0 - Create sample ham radio tests, helps pass the FCC tests.. (Shareware) Posted: 24 Oct 2011 03:12 AM PDT  Elmer creates sample tests to help you prepare for your ham radio written examination. It contains all FCC question pools for each of the five written exams: Novice, Technician, General, Advanced, and Extra Class. Elmer will grade your sample test, showing you which questions were answered incorrectly. It will also indicate if you passed the exam.
Mac OS X 10.1 or later. Download Now This posting includes an audio/video/photo media file: Download Now |
| Kerio Connect 7.2.4 - Powerful & secure internet mail server.. (Demo) Posted: 24 Oct 2011 03:25 AM PDT  Kerio Connect (was Kerio MailServer) is an Exchange alternative, allowing companies to collaborate via email, shared contacts, shared calendars, notes and tasks. Kerio MailServer comes with:
Version 7.2.4: Kerio Connect
Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 24 Oct 2011 04:24 AM PDT The guys in marketing have identified a serious lack of love in the market place – and the boss is blaming you! Take on the role of cupid and try to save your job by increasing the levels of love in the air! Armed with your standard issue Love Laser (this is 2011 after all, who uses arrows these days?), it's down to you to perfect the art of love making and pair together anything you can find. What's that - you want a tip do you? Ok, well look out for those special combinations of objects that will award you bonus points! There are over 150 combinations, so something is seriously wrong if you can't find some of them! Oh, and did I mention extra bonuses in the form of 19 achievements! ...So what are you waiting for – load your Love Laser and make love happen! FEATURES: - Two game modes: practice & normal - OpenFeint Leaderboards and Achievements - Over 170 combinations to discover - Simple, intuitive, single tap gameplay - Experiment with different pairings to see what they create - Checklist showing the combinations you've found and clues to those you haven't - Additional fun content will be made available. |
| Posted: 24 Oct 2011 03:59 AM PDT Powered by FIFA gameplay engine, and introducing Street Ball Control, FIFA Street will deliver an arsenal of groundbreaking street dribbling styles and trick moves that ignite the one-on-one battles within matches. Whether performing one panna after another without breaking a sweat the way street football is played in Amsterdam, or a physical, fight-for-possession style the way footballers compete in London, fans will enjoy a superior fidelity of ball control and responsiveness than anything ever experienced in a football videogame. Plus, for the first time ever, utilize aerial skills to maneuver past opponents, an all-new sophisticated one-touch passing system for quick, precision passes, and over 50 never-before-experienced skill moves. Play with and against the stars of the most popular football clubs in the world—or real-life street footballers—and compete at more than 35 locations around the world. From one-on-one battles in parking lots and parks to prestigious 5v5 tournaments on the streets of the world's biggest cities, FIFA Street will replicate the unique street football style. Plus, it will feature a host of modes and online features that will be revealed in the months ahead that will make the game a social, connected experience. |
| Background image by "WhishingOnAsTar!" Posted: 24 Oct 2011 03:12 AM PDT Thanks to Boing Boing reader "WhishingOnAsTar!" for submitting today's background image to the Boing Boing Flickr pool!  |
| MiJournal 1.0.6 - Feature-rich journaling application.. (Shareware) Posted: 24 Oct 2011 02:53 AM PDT  MiJournal gives you a feature-rich set of options for organizing your daily record of occurrences, experiences, or observations. MiJournal is much like the paper journals from days of old, except that you can back it up, drag-and-drop photos and videos into your entries, password protect it, and encrypt it. Plus, you will never run out of Journal Entry pages! MiJournal makes it easy to add photos and videos to your journal entries. If a picture is worth a thousand words, this will save you some typing! Just drag and drop Images, Videos, sound clips - even links to emails and iCal items into the main window Version 1.0.6:
Mac OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Folder Icon Creator 3.0.2 - Create custom icons for your Mac.. (Shareware) Posted: 24 Oct 2011 02:50 AM PDT  Folder Icon Creator is an app to customize the icons on your Mac. The program comes pre-bundled with hundreds of icons that you can use to create custom folder icons and custom file icons on your Mac. Not only are their hundreds of icons included with the program, but you can create a library using ANY .png images, and convert them to icons easily using this program. You can make custom, personalized icons simply by using an image or photograph that you have (or downloaded from the internet), and dragging it into your custom icon library!You can assign custom icons in batches, or one at a time using drag-and-drop.The Folder Icon Maker comes pre-bundled with hundreds of icons, and we frequently release updates with additional icons. All updates are free forever! Version 3.0.2:
Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 24 Oct 2011 12:00 AM PDT Bioassay-guided fractionation of the diethyl ether fraction of a water extract of Picea schrenkiana needles led to the isolation of the phenolic compound 3,4-dihydroxy- acetophenone (DHAP). The allelopathic effects of DHAP were evaluated under laboratory conditions on P. schrenkiana, rice (Oryza sativa L.), wheat (Triticum aestivum L.), radish (Raphanus sativus L.), lettuce (Latuca sativa L.), cucumber (Cucumis sativus L.) and mung bean (Phaseolus radiatus L.). DHAP significantly inhibited seed germination and seedling growth of P. schrenkiana at concentrations of 2.5 mM and 0.5 mM (p < 0.05). Soil analysis revealed that P. schrenkiana forest soils contained exceptionally high DHAP concentrations (mean = 0.51 ± 0.03 mg/g dry soil), sufficient to inhibit natural P. schrenkiana recruitment. DHAP also exhibited strong allelopathic potential. It significantly inhibited wheat and lettuce seed germination at concentrations of 1 mM and 0.5 mM (p < 0.05). The active compound also completely inhibited root growth of the six test species at high concentrations. Our results suggest a dual role of DHAP, both as an allelochemical and as an autotoxicant. The potential for a single plant needle-leached compound to influence both inter- and intra-specific interactions emphasized the complex effects that plant secondary metabolites might have on plant population and community structure. |
| Pharmaceuticals, Vol. 4, Pages 1381-1399: Lipothioureas as Lipids for Gene Transfection: A Review Posted: 24 Oct 2011 12:00 AM PDT Non-viral gene therapy requires innovative strategies to achieve higher transfection efficacy. A few years ago, our group proposed bioinspired lipids whoseinteraction with DNA was not based on ionic interactions, but on hydrogen bonds. We thusdeveloped lipids bearing a thiourea head which allowed an interaction with DNAphosphates through hydrogen bonds. After a proof of concept with a lipid bearing threethiourea functions, a molecular and cellular screening was performed by varying all partsof the lipids: the hydrophobic anchor, the spacer, the linker, and the thiourea head. Twolipothiourea-based structures were identified as highly efficient in vitro transfecting agents.The lipothioureas were shown to reduce non specific interactions with cell membranes anddeliver their DNA content intracellularly more efficiently, as compared to cationiclipoplexes. These lipids could deliver siRNA efficiently and allowed specific cell targetingin vitro. In vivo, thiourea lipoplexes presented a longer retention time in the blood and lessaccumulation in the lungs after an intravenous injection in mice. They also inducedluciferase gene expression in muscle and tumor after local administration in mice.Therefore, these novel lipoplexes represent an excellent alternative to cationic lipoplexes astransfecting agents. In this review we will focus on the structure activity studies thatpermitted the identification of the two most efficient thiourea lipids. |
| Posted: 24 Oct 2011 12:00 AM PDT In complex mixture toxicology, there is growing emphasis on testing environmentally representative doses that improve the relevance of results for health risk assessment, but are typically much lower than those used in traditional toxicology studies. Traditional experimental designs with typical sample sizes may have insufficient statistical power to detect effects caused by environmentally relevant doses. Proper study design, with adequate statistical power, is critical to ensuring that experimental results are useful for environmental health risk assessment. Studies with environmentally realistic complex mixtures have practical constraints on sample concentration factor and sample volume as well as the number of animals that can be accommodated. This article describes methodology for calculation of statistical power for non-independent observations for a multigenerational rodent reproductive/developmental bioassay. The use of the methodology is illustrated using the U.S. EPA's Four Lab study in which rodents were exposed to chlorinated water concentrates containing complex mixtures of drinking water disinfection by-products. Possible experimental designs included two single-block designs and a two-block design. Considering the possible study designs and constraints, a design of two blocks of 100 females with a 40:60 ratio of control:treated animals and a significance level of 0.05 yielded maximum prospective power (~90%) to detect pup weight decreases, while providing the most power to detect increased prenatal loss. |
| Posted: 24 Oct 2011 02:30 AM PDT Chess Olympiad Tromso 2014, agreement signed Tromso was chosen as a host city of the Chess Olympiad 2014 during the General Assembly in 2010, where the mojority voted for Norway . This posting includes an audio/video/photo media file: Download Now |
| Posted: 23 Oct 2011 06:56 PM PDT [Platform: Mobile (iPhone, iPod Touch)] Mage Gauntlet, from Hook Champ and Super QuickHook creator Rocketcat Games, is the modern 16-bit action role playing game you've been waiting for. Everything about it is retro, from the level design to the pixel art, only instead of having to dust off your SNES, you just fire up your iOS device. In a decidedly awesome twist, this RPG doesn't take hours of playing before you can get into it, opening it up for shorter mobile sessions and casual gamers alike! |
| Cancers, Vol. 3, Pages 3957-3971: Emerging Evidence for MicroRNAs as Regulators of Cancer Stem Cells Posted: 24 Oct 2011 12:00 AM PDT Cancer stem cells are defined as a subpopulation of cells within a tumor that are capable of self-renewal and differentiation into the heterogeneous cell lineages that comprise the tumor. Many studies indicate that cancer stem cells may be responsible for treatment failure and relapse in cancer patients. The factors that regulate cancer stem cells are not well defined. MicroRNAs (miRNAs) are small non-coding RNAs that regulate translational repression and transcript degradation. miRNAs play a critical role in embryonic and inducible pluripotent stem cell regulation and emerging evidence supports their role in cancer stem cell evolution. To date, miRNAs have been shown to act either as tumor suppressor genes or oncogenes in driving critical gene expression pathways in cancer stem cells in a wide range of human malignancies, including hematopoietic and epithelial tumors and sarcomas. miRNAs involved in cancer stem cell regulation provide attractive, novel therapeutic targets for cancer treatment. This review attempts to summarize progress to date in defining the role of miRNAs in cancer stem cells. |
| Quicksilver 61 - Application launcher and much more.. (Free) Posted: 23 Oct 2011 08:59 PM PDT  Quicksilver is a unified, extensible interface for working with applications, contacts, music, and other data. Anyone using a computer (and the Macintosh is no exception) spends a lot of time locating files and applications, and then carrying out actions on those items. The Finder is a reasonably good tool for getting a visual overview of the contents of your disk, but it isn't ideal for quickly locating and manipulating files, especially if you have a deep and complicated folder structure, or if you prefer keyboard navigation to using the mouse. Quicksilver allows you to find what you need quickly and easily, while keeping your hands on the keyboard. For example, if you want to launch an application hidden in the depths of your file system, simply activate Quicksilver with a keystroke, type a few letters of the application's name, then hit Return or Enter to launch it. When you don't need Quicksilver, it keeps out of your way, preserving precious screen real estate, and yet you can summon it instantly with a key stroke - just like Mercury the winged messenger. Actually, Roman mythological texts are remarkably silent on whether Mercury could be summoned with a key stroke, but it would have been great if he could. Quicksilver will certainly make you feel as if you have god-like powers. Quicksilver indexes and parses selected parts of the contents of your hard drive in the Catalog, so that it locates and displays the items matching your search really quickly. If you are a programmer or an uber-geek, you will be glad to know that you can extend and customise Quicksilver until it does exactly what you want it to. The modular structure also means that the application will never be bloated: You only load the modules that you find useful An older, 10.3 compatible version is available: http://getqs.blacktree.com/b36/
Mac OS X 10.6 or later. Download Now |
| iFFmpeg 2.7.0 - Convert multimedia files between formats.. (Shareware) Posted: 23 Oct 2011 08:59 PM PDT  iFFmpeg is a graphical front-end for FFmpeg, a command-line tool used to convert multimedia files between formats. The command line instructions can be very hard to master/understand, so iFFmpeg does all the hard work for you. This allows you to use FFmpeg without detailed command-line knowledge. Version 2.7.0:
Download Now This posting includes an audio/video/photo media file: Download Now |
| OnyX 2.4.2b3 - Mac OS X maintenance and optimization tool.. (Free) Posted: 23 Oct 2011 08:59 PM PDT  OnyX is a multifunction utility for Mac OS X. It allows you to verify the Startup Disk and the structure of its System files, to run miscellaneous tasks of system maintenance, to configure the hidden parameters of the Finder, Dock and of some of Apple's own applications, to delete caches, to remove a certain number of files and folders that may become cumbersome and more. Version 2.4.2b3:
Mac OS X 10.7 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Asia Shippin' Out October 23-29: Battlefield 3 Posted: 23 Oct 2011 09:48 PM PDT EA's contribution to digital modern warfare, a new portable Final Fantasy title, and a vampiric add-on are highlights for the week.
The blockbuster titles just keep on rolling. Helming this week's big releases is Battlefield 3, the latest in the hit Battlefield series that started in 2002. The game will feature large-scale multiplayer battles, an updated Frostbite 2 engine to show off destructibility and detailed environments, and a campaign mode set in the year 2014 where PLR Iranian insurgents are planning to start a war. The game will be out on PC, Xbox 360, and PS3 tomorrow. On a related note, gamers can check out GameSpot's new reality online show The Controller, which features Battlefield 3. Next up is Final Fantasy Type-0 for the PSP, due on October 28 in its native Japanese language. The long-awaited new entry in the Fabula Nova Crystallis series of Final Fantasy titles (starting with Final Fantasy XIII) will feature real-time and action-based combat, a three-party system where gamers can switch them with 12 reserve warriors, and ad hoc multiplayer with other PSP users. This PSP game is the first to use two UMDs. After that is Kirby's Return to Dreamland on the Wii. The game is a return to form for Kirby's platforming and power-stealing shenanigans. This title will also feature four-player simultaneous co-op with other Kirby clones and new copy abilities for players to experiment with. Finally, fans of inFamous 2 can download the latest stand-alone title called inFamous 2: Festival of Blood. This side story is a "what if" scenario where main character Cole is a vampire and has to fight off other vampires in New Marais. The game features new powers and new user-generated content tools to complement the feature introduced in inFamous 2. The downloadable title will be out this Tuesday; gamers do not need a copy of inFamous 2 to play this. October 24 October 25 October 28
Read and Post Comments | Get the full article at GameSpot "Asia Shippin' Out October 23-29: Battlefield 3 " was posted by Jonathan Leo Toyad on Sun, 23 Oct 2011 21:48:37 -0700 |
| You are subscribed to email updates from Games To stop receiving these emails, you may unsubscribe now. | Email delivery powered by Google |
| Google Inc., 20 West Kinzie, Chicago IL USA 60610 | |
Комментариев нет:
Отправить комментарий