Games |
- Recon Suite 8.52 - Inventory your network devices and computers.. (Commercial)
- Composer 8.52 - Point-and-click through the package creation process.. (Commercial)
- Casper Suite 8.52 - Sysadmin tool for inventory, imaging, updating, system maintenance.. (Commercial)
- Pharmaceuticals, Vol. 5, Pages 447-459: The Signalling Role of the avβ5-Integrin Can Impact the Efficacy of AAV in Retinal Gene Therapy
- JPM, Vol. 2, Pages 50-70: Infectious Disease Management through Point-of-Care Personalized Medicine Molecular Diagnostic Technologies
- Viruses, Vol. 4, Pages 725-733: Post-Transcriptional Control of Type I Interferon Induction by Porcine Reproductive and Respiratory Syndrome Virus in Its Natural Host Cells
- Imaging Suite 8.52 - All-in-one toolbox for building and deploying images.. (Commercial)
- As In Chess, As In Life
- Battlefield 3 producer says blocking used games can be beneficial - Report
- Swords and Soldiers HD Launch Trailer
- Mt. Eddie & Classic Characters - SSX Launch Trailer
- Konami launching Zone of the Enders special event
- Sound Byte: Meet the Composer - Richard Jacques
- RG3 Media Day at Baylor - NCAA Football 13 Video
- Playbook - NCAA Football 13 Trailer
- League of Lessons: The Bruiser (Part Two)
- Call of Duty: Black Ops II - It's a Conspiracy Interview
- The Five Biggest Surprises About Call of Duty: Black Ops II
- Call of Duty: Black Ops II - The Future Is Black Interview
- Sniper Elite V2 Review
Recon Suite 8.52 - Inventory your network devices and computers.. (Commercial) Posted: 02 May 2012 02:38 AM PDT Recon Suite... In an increasingly compliance-driven world, immediate access to accurate information is critical to driving down costs and maintaining obligations. The Recon Suite provides a simple, low-cost way to inventory your network devices and computers, including Mac OS 9, iPhone, Mac OS X, and Windows machines. Every application, font, plug-in and computer on the network communicates with, and is documented to, the JAMF Software Server (JSS). Key Features:
Version 8.52: Release notes were unavailable when this listing was updated. Server You can host the JAMF Software Server (JSS) on any server that meets the following minimum requirements:
Tested operating systems include: Mac OS X Server 10.6
Although you can install the JSS on any server that meets the minimum requirements, the JSS Installers for Mac, Linux, and Windows have additional requirements. Inventory Recon can gather inventory information for computers running the following operating systems:
Older versions of Recon (available by contacting JAMF Software Support) can submit inventory information for computers running the following operating systems:
Download Now |
Composer 8.52 - Point-and-click through the package creation process.. (Commercial) Posted: 02 May 2012 02:46 AM PDT Composer, the easy-to-use software package-creation utility for IT systems administrators. Composer 7 allows administrators to easily create software installation packages for computers operating within Mac networks. When software is purchased from manufacturers for use in enterprise-level networks, it often needs to be configured or customized by IT personnel to meet the needs of the end-users receiving it. By creating "packages", any changes or configurations can be created prior to distribution, so that the software arrives at the end-user already pre-configured and ready for immediate use. Creating packages that are tailored to end-user configurations allows IT administration to save time and resources-as well as network bandwidth, since only the required data is being distributed. Composer is a utility that creates such packages. Part of the Casper Suite, as well as being available as a standalone application, Composer lets users point-and-click their way through the package creation process. In doing so it quickly and easily creates software and/or file installation packages, in .pkg or .dmg format, for deployment with Apple Remote Desktop or any other patch management system. A video with detailed information about the new features in Composer 7 is available on the JAMF Software website.
Version 8.52: Release notes were unavailable when this listing was updated.
Download Now |
Posted: 02 May 2012 02:04 AM PDT The Casper Suite simplifies the life of system administrators with a comprehensive platform to manage Mac OS X computers and iOS mobile devices. The Casper Suite increases the efficiency of your IT staff, reduces the cost of ownership, and minimizes liability by providing a framework that enforces software licensing compliance, security standards, energy usage, and other organizational rules and requirements. Working with Mac administrators in business, education, and government throughout the world, JAMF Software developers have identified eight major tenets of Mac OS X client management and four major tenets of iOS mobile device management. The Casper Suite provides a comprehensive framework to manage all twelve tenets in a single console. Mac OS X client lifecycle management iOS mobile device management (MDM) Within these tenets, the Casper Suite offers features and functions that provide IT administrators with best practice strategies to meet the challenges of supporting Mac OS X and iOS in the enterprise, allowing your organization to build and sustain a stable, cost-effective, and user-friendly computing environment. The Casper Suite is a powerful framework around which your IT ecosystem can be unified and extended to manage both Mac OS X and iOS devices from a single console. Normalize your IT administration with the only client management solution developed exclusively for the Apple platform. Version 8.52:
You can host the JAMF Software Server (JSS) on any server that meets the following minimum requirements:
Tested operating systems include: Mac OS X Server 10.6
Although you can install the JSS on any server that meets the minimum requirements, the JSS Installers for Mac, Linux, and Windows have additional requirements. Download Now |
Posted: 02 May 2012 12:00 AM PDT Sub-retinal injection of the common AAV2 pseudotypes frequently results in strong transduction of the retinal pigment epithelium (RPE) as well as the retina itself. This has been of benefit to date in human clinical trials using AAV, where the disease target is in the RPE. However, many mutations predisposing to retinal disease are located in the photoreceptor cells, present in the neural retina and not the RPE; in this case the sub-retinal injection route may cause an effective "loss" of therapeutic AAV to the RPE. The avβ5 integrin receptor is highly expressed on the apical surface of the RPE, and is essential to the daily phagocytosis of the outer segment tips of photoreceptor cells. The transduction efficiency of AAV was tested in the retinas of β5−/− mice lacking this receptor and showing defects in photoreceptor outer segment phagocytosis. Following sub-retinal injection of AAV2/5-eGFP, fluorescence was found to be stronger and more widespread in the neural retina of β5−/− mice compared to wild-types with greatly reduced fluorescence in the RPE. Increased levels of the phagocytic signalling protein MFG-E8, the ligand for the avβ5 integrin receptor, is found to have a moderate inhibitory effect on AAV transduction of the retina. However the opposite effect is found when only the integrin-binding domain of MFG-E8, the RGD (Arginine-Glycine-Aspartic acid) domain, was increased. In this case RGD enhanced AAV-mediated retinal transduction relative to RPE transduction. These results are presented for their relevance for the design of AAV-based retinal gene therapy strategies strategies targeting retinal/photoreceptor cells. |
Posted: 02 May 2012 12:00 AM PDT Infectious disease management essentially consists in identifying the microbial cause(s) of an infection, initiating if necessary antimicrobial therapy against microbes, and controlling host reactions to infection. In clinical microbiology, the turnaround time of the diagnostic cycle (>24 hours) often leads to unnecessary suffering and deaths; approaches to relieve this burden include rapid diagnostic procedures and more efficient transmission or interpretation of molecular microbiology results. Although rapid nucleic acid-based diagnostic testing has demonstrated that it can impact on the transmission of hospital-acquired infections, we believe that such life-saving procedures should be performed closer to the patient, in dedicated 24/7 laboratories of healthcare institutions, or ideally at point of care. While personalized medicine generally aims at interrogating the genomic information of a patient, drug metabolism polymorphisms, for example, to guide drug choice and dosage, personalized medicine concepts are applicable in infectious diseases for the (rapid) identification of a disease-causing microbe and determination of its antimicrobial resistance profile, to guide an appropriate antimicrobial treatment for the proper management of the patient. The implementation of point-of-care testing for infectious diseases will require acceptance by medical authorities, new technological and communication platforms, as well as reimbursement practices such that time- and life-saving procedures become available to the largest number of patients. |
Posted: 02 May 2012 12:00 AM PDT Porcine reproductive and respiratory syndrome virus (PRRSV) is not only a poor inducer of type I interferon but also inhibits the efficient induction of type I interferon by porcine transmissible gastroenteritis virus (TGEV) and synthetic dsRNA molecules, Poly I:C. However, the mechanistic basis by which PRRSV interferes with the induction of type I interferon in its natural host cells remains less well defined. The purposes of this review are to summarize the key findings in supporting the post-transcriptional control of type I interferon in its natural host cells and to propose the possible role of translational control in the regulation of type I interferon induction by PRRSV. |
Imaging Suite 8.52 - All-in-one toolbox for building and deploying images.. (Commercial) Posted: 02 May 2012 01:53 AM PDT The Imaging Suite's modular approach to imaging makes building multiple images easy by building configurations from a library of custom packages. Utilizing the same set of operating system and application packages to create multiple configurations ensures that each configuration is made up of identical components. Most imaging utilities are based on a monolithic approach in which administrators build one base image that includes every element for every machine. The base image is then copied and adjusted to accommodate each configuration required by the network. This approach results in many large, monolithic images that require both storage and maintenance. The Imaging Suite's package-based approach to imaging reduces storage requirements, tracks changes, ensures consistency across the organization, and eliminates post-imaging activities. Key Features:
Version 8.5.2: Server You can host the JAMF Software Server (JSS) on any server that meets the following minimum requirements: ‚‚
Tested operating systems include:
Imaging: Download Now |
Posted: 02 May 2012 12:51 AM PDT Jennifer DuBois's new novel asks the central question, How do you keep going when you know things are going to end badly? The book is A Partial History of Lost Causes . This posting includes an audio/video/photo media file: Download Now |
Battlefield 3 producer says blocking used games can be beneficial - Report Posted: 02 May 2012 12:10 AM PDT DICE developer Patrick Bach tells CVG that blocking used games on next-gen consoles is both a win and a loss; says a lot of game companies lose out on second-hand sales.
Battlefield 3 executive producer Patrick Bach has told Computer and Video Games (CVG) that blocking used games on next-gen consoles can be "a win and a loss".
The DICE developer weighed in on the rumours concerning Microsoft and Sony implementing anti-used-game measures in their respective future-generation consoles. Speaking to CVG, Bach said the measures would only be a loss if it meant consumers would find themselves with fewer games for the same amount of money. "But in theory, you could see it the other way, because a lot of companies making games today are struggling based on second-hand sales," Bach told CVG. "So on the positive side, you could see more games being created because of this, and also more new IPs, because there'd be a bigger market for games that don't have, for instance, multiplayer. There could be awesome single-player-only games, which you can't really do these days because people just pirate them, which is sad." "From a gamer perspective, if you want to buy as many games as possible, then this could be a problem. But if you want more diverse games, then it's a more positive thing than negative. The only thing I know is that people are not doing it to be evil and stupid; it's about trying to create some benefits for consumers." Despite news that next-generation consoles are not expected until at least next year, several developers have already expressed their opinions on the idea of blocking used games. Crytek director of creative development Rasmus Hojengaard recently backtracked from a statement in which he had remarked that from a business perspective, next-gen consoles that would not allow consumers to play used games would be "absolutely awesome". Other developers who have spoken out against used sales recently include ex-THQ executive Richard Browne, Elite creator David Braben, Volition design director Jameson Durall, and Silicon Knights founder Denis Dyack. However, not all voices in the industry are against used games. Saber Interactive CEO Matthew Karch said in February that blocking used games is unfair, while Witcher developer CD Projekt Red managing director Adam Badowski took a populist stance with his statement on the issue. Read and Post Comments | Get the full article at GameSpot "Battlefield 3 producer says blocking used games can be beneficial - Report" was posted by Laura Parker on Wed, 02 May 2012 00:10:40 -0700 |
Swords and Soldiers HD Launch Trailer Posted: 01 May 2012 10:52 PM PDT Swords and Soldiers HD is now available on Google Play.
Read and Post Comments | Get the full article at GameSpot "Swords and Soldiers HD Launch Trailer" was posted by MikeTao on Tue, 01 May 2012 22:52:37 -0700 |
Mt. Eddie & Classic Characters - SSX Launch Trailer Posted: 01 May 2012 10:49 PM PDT The SSX Mt. Eddie & Classic Characters DLC pack is available now!
Read and Post Comments | Get the full article at GameSpot "Mt. Eddie & Classic Characters - SSX Launch Trailer" was posted by MikeTao on Tue, 01 May 2012 22:49:00 -0700 |
Konami launching Zone of the Enders special event Posted: 01 May 2012 10:48 PM PDT Spotlight event for Zone of the Enders HD Edition to be held in Shinjuku, Japan.
Konami recently announced that it will be hosting a Zone of the Enders premium event, with the spotlight on a preview of Zone of the Enders HD Edition. The public event will be called "Zone of the Enders HD Night Fastest in the Universe Reboot Preview". The event will be held at the Shinjuku Wald 9 theater in Tokyo, Japan, and will happen on May 25. Staff members who worked on the series who will make an appearance include Hideo Kojima, Yoji Shinkawa, Noriaki Okamura, Shuyou Murata, and Nobuyoshi Nishimura. Attendees will also get to see new updates on the remake, as well as a special live performance by a yet-to-be-announced artist. The ticket price for the event will cost the public 3,000 yen (A$37). Attendants can buy them online at the Konami Style site starting today. Zone of the Enders HD Edition is slated to be out later this year. Read and Post Comments | Get the full article at GameSpot "Konami launching Zone of the Enders special event" was posted by Jonathan Toyad on Tue, 01 May 2012 22:48:21 -0700 |
Sound Byte: Meet the Composer - Richard Jacques Posted: 01 May 2012 10:45 PM PDT We talk to the former Sega Europe composer about his work on James Bond 007: Blood Stone, and the upcoming LittleBigPlanet 2: The Muppets DLC.
Get the full article at GameSpot "Sound Byte: Meet the Composer - Richard Jacques" was posted by Jonathan Toyad on Tue, 01 May 2012 22:45:59 -0700 |
RG3 Media Day at Baylor - NCAA Football 13 Video Posted: 01 May 2012 10:38 PM PDT Go behind-the-scenes with #2 overall pick Robert Griffin III at his stomping grounds, Baylor University, in this video for NCAA Football 13.
Read and Post Comments | Get the full article at GameSpot "RG3 Media Day at Baylor - NCAA Football 13 Video" was posted by MikeTao on Tue, 01 May 2012 22:38:45 -0700 |
Playbook - NCAA Football 13 Trailer Posted: 01 May 2012 10:36 PM PDT Check out some of the new features in NCAA Football 13!
Read and Post Comments | Get the full article at GameSpot "Playbook - NCAA Football 13 Trailer" was posted by MikeTao on Tue, 01 May 2012 22:36:04 -0700 |
League of Lessons: The Bruiser (Part Two) Posted: 01 May 2012 10:33 PM PDT On this next instalment detailing the bruiser role in League of Legends, we focus on team dynamics, and the best tools you should use for the job.
Get the full article at GameSpot "League of Lessons: The Bruiser (Part Two)" was posted by Joshua Lim on Tue, 01 May 2012 22:33:17 -0700 |
Call of Duty: Black Ops II - It's a Conspiracy Interview Posted: 01 May 2012 09:00 PM PDT The future is about robots and rare earth metals.
Read and Post Comments | Get the full article at GameSpot "Call of Duty: Black Ops II - It's a Conspiracy Interview" was posted by DanM on Tue, 01 May 2012 21:00:00 -0700 |
The Five Biggest Surprises About Call of Duty: Black Ops II Posted: 01 May 2012 09:00 PM PDT Is there still room for creativity in Call of Duty? Treyarch hopes so.
After all the rumors and leaks, it's finally official: Treyarch is at work on a sequel to Black Ops, due for arrival later this year. This sort of news isn't exactly shocking, of course, considering that Call of Duty has long been one of those annualized series where gossiping about the next game is a bit like spreading rumors about tomorrow's sunrise. But just because the existence of Black Ops II is a foregone conclusion doesn't mean that the content of the game is on that same level of predictability. In fact, the team at Treyarch has got quite a number of tricks up its sleeve for this upcoming first-person shooter. The core action is very much Call of Duty, but the overall package might just surprise you.
It's set in the future and the pastThe Call of Duty franchise has always been fond of the idea of dual protagonists, whether it was alternating between two separate theaters of war in the World War II days or two different elite tactical units in the Modern Warfare franchise. Black Ops II is out to do the same thing, but with one very different twist: instead of being separated by geography, the playable characters are separated by decades of time. One half of the game picks up immediately after Black Ops, with you following the journey of Frank Woods, who, as luck would have it, didn't quite die at the end of the last game. Whether he's riding on horseback alongside mujahideen during the Afghan Civil War or off pursuing Russian secrets in some other corner of the world, Woods' adventures will take him through some of the later stages of the Cold War. The other half of the campaign, though, kicks off in the year 2025, when advanced weapon technologies rule the day. This half of the campaign is filled with drone warfare (you can hack and deploy drones in the heat of combat), robotic quadrupeds roaming the battlefield, and fancy weapon systems that let you do some pretty crazy stuff with your basic firearms (like hold the trigger longer for a charged fire). Even subtle things like the general aesthetic of the heads-up display or the style of the music have a more futuristic feel to them. If done right, this type of setup could make for a very interesting experience. There's going to be a lot of contrast between the tone and technologies of these two halves of the campaign, and bouncing between the two could be a lot of fun. Treyarch is keen to stress that it has done this to examine some distinct historical parallels (the old Cold War with Russia and the new one with China), which could be interesting if the thoughtfulness that goes into that premise isn't overshadowed by sheer chaos and spectacle--something that's always a risk when it comes to storytelling in Call of Duty.
It has branching storylinesCall of Duty games have long been this industry's go-to example for linear storytelling. Once you have finished the mile-a-minute campaigns, there has never been a tremendous reason to go back and play through the story again. With Black Ops II, however, Treyarch wants to give you some control over how the story progresses and thus add a reason to go back and experience different events. It's doing this through a combination of old-fashioned decision-making and allowing mission failures to alter the story rather than simply lead to a game-over screen. Did you manage to kill that one antagonist before he got away? Did you successfully protect that VIP? Instances such as these (if not these examples specifically) can occasionally lead to different outcomes depending on how well you do. Ideally, this method of storytelling will be more nuanced than just "kill all the men, get the good ending" versus "kill most of the men, get the slightly worse ending." We're hoping to see more moral gray area, where you are given the chance to make difficult decisions that alter the game on top of how you perform in battle. This sort of narrative system has the potential to seriously alter how you experience a Call of Duty campaign, and we're hoping that Treyarch can pull it off in a meaningful way.
It's occasionally a real-time strategy gameTreyarch is working on a new game mode for Black Ops II called Strikeforce, which is the studio's attempt to add a more hands-off, sandbox experience for players who want to run-and-gun on their own terms. What Strikeforce does is drop you into a large environment with a number of AI squadmates (sadly, this mode isn't co-op) and then give you a series of objectives spread throughout the map. It's basically the game giving you a bunch of space, a bunch of toys, and a bunch of enemies to take care of how you see fit. The novel bit is that you don't have to play as the foot soldiers on the ground. You can bounce out to a sort of all-seeing-eye camera that lets you quickly scan across the map and issue orders to the troops on the ground. And since this is the year 2025 (the supplementary game modes like Strikeforce and competitive multiplayer all stick to the future), you can also issue orders to drones, and even play as them from a first-person perspective (including air and ground units). The whole thing is basically Call of Duty's version of a toy chest come to life. You can either pretend to be each little unit on the ground, or simply play out the entire match as the disembodied overlord looming over the battle, telling everyone what to do and where to go.
It has a villain Treyarch wants you to care aboutThink of all the things the Call of Duty franchise has done well over the years: the sensation of being in the middle of a chaotic warzone, the terrific feel of the weapons, the exciting (and occasionally eccentric) set pieces. With this next game, Treyarch is hoping to add "interesting and multifaceted villain" to that list. While the studio isn't going into too much detail about this antagonist's identity, they did mention that they'll be using the full span of the campaign--both the past and future--to establish the villain as a young man, show his descent into evil, and reveal the full extent of that trajectory come 2025. To help build this villain, Treyarch has been working with screenwriter David Goyer, whose credits include Batman Begins and The Dark Knight. Remember Heath Ledger as the Joker? That's the sort of lightning Treyarch is hoping to bottle up with the help of Goyer. Game director Dave Anthony explains it like this: "If you look at a show like The Sopranos, the main character is essentially a villain. Not only a villain, but a cold-blooded murderer. But you're presented with somebody that you actually understand as a human being and empathize with. And then suddenly you'll see them do something that's so horrific that it puts you in a real conflict. That's the approach we're taking with the villain of Black Ops II."
It's more influenced by e-sports than you thinkWith last year's Modern Warfare 3, Infinity Ward made the call to forgo LAN support. It was a decision that led competitive gaming leagues like MLG to drop MW3 from the pro circuits. Treyarch's approach to e-sports couldn't be more different. Black Ops II multiplayer design lead David Vonderhaar says that tailoring their game to resonate with the e-sports community is a huge goal for Treyarch. "E-sports has a really big influence. It helps us envision ways we can make the game for a competitive mindset, so there's elements of e-sports directly influencing the game design in multiplayer," says Vonderhaar. "But what's also really fascinating is e-sports as a spectator experience." "The theater was fantastic, millions of people making millions of videos. But what's also fantastic is all these people who watch games get played. I just read this stat a couple days ago: 3 billion minutes per month of people watching people play video games. Three billion minutes! I'm thinking, man, Call of Duty could be 3 billion minutes if it was fun to watch. So this is impacting the game design. Making the game fun to watch is a big part of our agenda." You can expect to see Black Ops II hit stores on November 13. Stay tuned for more coverage once next month's E3 rolls around. Read and Post Comments | Get the full article at GameSpot "The Five Biggest Surprises About Call of Duty: Black Ops II" was posted by Shaun McInnis on Tue, 01 May 2012 21:00:00 -0700 |
Call of Duty: Black Ops II - The Future Is Black Interview Posted: 01 May 2012 09:00 PM PDT Run black ops in the past and the future.
Read and Post Comments | Get the full article at GameSpot "Call of Duty: Black Ops II - The Future Is Black Interview" was posted by DanM on Tue, 01 May 2012 21:00:00 -0700 |
Posted: 01 May 2012 07:37 PM PDT Sniper Elite V2 is a satisfying shooting gallery, though it often does a lackluster job maintaining the illusion.
Score: 6.0 / fair Get the full article at GameSpot "Sniper Elite V2 Review" was posted by Chris Watters on Tue, 01 May 2012 19:37:43 -0700 |
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