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- DVDFab File Transfer 8.1.8.5 - Transfer converted files to portable media device.. (Demo)
- DVDFab DVD Creator 8.1.8.5 - Create DVDs from any video file.. (Shareware)
- Innocent pick-up truck dies horribly 17 times over to demonstrate CryEngine 3 - but it was totally worth it
- IJERPH, Vol. 9, Pages 2045-2056: Molecular Detection and Drug Resistance of Mycobacterium tuberculosis Complex from Cattle at a Dairy Farm in the Nkonkobe Region of South Africa: A Pilot Study
- Molecules, Vol. 17, Pages 6465-6480: Influence of Chemical Extraction Conditions on the Physicochemical and Functional Properties of Polysaccharide Gum from Durian (Durio zibethinus) Seed
- Molecules, Vol. 17, Pages 6449-6464: The Coumarin Psoralidin Enhances Anticancer Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)
- Molecules, Vol. 17, Pages 6434-6448: Synthesis, Spectroscopy, Thermal Analysis, Magnetic Properties and Biological Activity Studies of Co(II) and Co(II) Complexes with Schiff Base Dye Ligands
- Molecules, Vol. 17, Pages 6424-6433: Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne
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- Southern Highlands Honors Heroes on Memorial Day
- Molecules, Vol. 17, Pages 6415-6423: Observation of 1,3-Diketones Formation in the Reaction of Bulky Acyl Chlorides with Methyllithium
- Sensors, Vol. 12, Pages 7157-7168: A Sub-ppm Acetone Gas Sensor for Diabetes Detection Using 10 nm Thick Ultrathin InN FETs
- Sensors, Vol. 12, Pages 7126-7156: Advancements in Transmitters and Sensors for Biological Tissue Imaging in Magnetic Induction Tomography
- Sensors, Vol. 12, Pages 7109-7125: Personal Pervasive Environments: Practice and Experience
- Sensors, Vol. 12, Pages 7095-7108: Passive Fluidic Chip Composed of Integrated Vertical Capillary Tubes Developed for On-Site SPR Immunoassay Analysis Targeting Real Samples
- Sensors, Vol. 12, Pages 7080-7094: Quartz Crystal Microbalance Aptasensor for Sensitive Detection of Mercury(II) Based on Signal Amplification with Gold Nanoparticles
- DVDFab HD Decrypter 8.1.8.5 - Make backup copies of your DVDs and BluRay discs.. (Free)
- DVDFab Blu-ray 3D Ripper 8.1.8.5 - Rip 3D Blu-rays.. (Shareware)
DVDFab Video Converter 8.1.8.5 - Convert video to other file formats.. (Shareware) Posted: 29 May 2012 03:32 AM PDT DVDFab Video Converter converts source video file on your Mac to next generation consoles like PS3 and mobile devices like iPod, PSP, ZUNE, cell phone, etc. Features Highlight:
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DVDFab File Transfer 8.1.8.5 - Transfer converted files to portable media device.. (Demo) Posted: 29 May 2012 03:16 AM PDT DVDFab File Transfer is a handy and easy to use tool for you to remove converted files on your Mac to devices such as iPod or PSP. More devices will be supported in the future. When DVD/Blu-ray/File to iPod and DVD/File to PSP conversion of DVDFab is finished, the DVDFab File Transfer will be activated automatically. It supports batch transfer to save time, and it is very fast. Features
Version 8.1.8.5: Release notes were unavailable when this listing was updated.
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DVDFab DVD Creator 8.1.8.5 - Create DVDs from any video file.. (Shareware) Posted: 29 May 2012 03:24 AM PDT DVDFab DVD Creator, the powerful Mac DVD Creator and DVD burner software, has the full capability to convert all sorts of video files into standard studio level DVD discs. The created DVD discs play on any built-in DVD optical drive that comes with any Mac products and standalone DVD players. That's to say, you can freely create your own DVDs out of all kinds of video files you downloaded, from your camcorder, iPod Touch, iPad, whatever! DVD Creator for Mac not only produces DVD discs from video files to play on standalone DVD player, but also creates standard DVD movie folders onto HDD for playing back with media players like DVDFab Media Player or burn to blank disc at any latter time convenience to you. Multi-threading, multi-core processing are implemented, so you don't need to worry about the speed, as it is super fast. This posting includes an audio/video/photo media file: Download Now |
Posted: 29 May 2012 12:00 AM PDT |
Posted: 29 May 2012 12:00 AM PDT Mycobacterium tuberculosis complex (MTBC) causes tuberculosis (TB) in humans and animals. We investigated the presence of MTBC in cattle milk and its drug resistance using polymerase chain reaction (PCR). Two hundred samples (100 mL each) were obtained from a dairy farm in the Nkonkobe region of South Africa. The samples were processed using the modified Petroff method. DNA was isolated using a Zymo Bacterial DNA kit and amplified using Seeplex® MTB Nested ACE assay. The Genotype® Mycobacterium tuberculosis-multidrug resistantplus (MTBDRplus) assay was used to perform drug susceptibility and detection of mutations conferring resistance to isoniazid (INH) and rifampicin (RIF). Eleven samples tested positive for MTBC DNA using the Seeplex® MTB Nested ACE assay. The Genotype® MTBDRplus assay showed that 10/11 samples were resistant to both INH and RIF i.e., multi-drug resistant (MDR). The most and least frequent rpoB mutations detected in RIF resistant samples were H526Y (9/10) and D516V (2/10) respectively. None of the INH resistant samples harbored mutations in the katG gene. However, all of them harbored the T8A mutation in the inhA gene. These results have clinical and epidemiological significance and calls for further studies and necessary actions to delineate the situation. |
Posted: 29 May 2012 12:00 AM PDT Durian seed is an agricultural biomass waste of durian fruit. It can be a natural plant source of non-starch polysaccharide gum with potential functional properties. The main goal of the present study was to investigate the effect of chemical extraction variables (i.e., the decolouring time, soaking temperature and soaking time) on the physicochemical properties of durian seed gum. The physicochemical and functional properties of chemically-extracted durian seed gum were assessed by determining the particle size and distribution, solubility and the water- and oil-holding capacity (WHC and OHC). The present work revealed that the soaking time should be considered as the most critical extraction variable affecting the physicochemical properties of crude durian seed gum. |
Posted: 29 May 2012 12:00 AM PDT Coumarins are a very common type of secondary plant metabolites with a broad spectrum of biological activities. Psoralidin is a naturally occurring furanocoumarin isolated from Psoralea corylifolia possessing anticancer and chemopreventive properties. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in cancer cells with no toxicity toward normal tissues. Endogenous TRAIL plays an important role in immune surveillance and defence against cancer cells. Coumarins can modulate TRAIL-mediated apoptosis in cancer cells. We examined the cytotoxic and apoptotic activities of psoralidin in combination with TRAIL on HeLa cancer cells. The cytotoxicity was measured by MTT and LDH assays. The apoptosis was detected using annexin V-FITC staining and mitochondrial membrane potential was evaluated using DePsipher staining by fluorescence microscopy. Death receptor (TRAIL-R1/DR4 and TRAIL-R2/DR5) expression was analyzed using flow cytometry. Psoralidin enhanced TRAIL-induced apoptosis in HeLa cells through increased expression of TRAIL-R2 death receptor and depolarization of mitochondrial membrane potential. Our study indicated that psoralidin augmented the anticancer effects of TRAIL and confirmed a potential use of coumarins in cancer chemoprevention. |
Posted: 29 May 2012 12:00 AM PDT Three azo group-containing Schiff base ligands, namely 1-{3-[(3-hydroxy-propylimino)methyl]-4-hydroxyphenylazo}-4-nitrobenzene (2a), 1-{3-[(3-hydroxypropyl-imino)methyl]-4-hydroxyphenylazo}-2-chloro-4-nitrobenzene (2b) and 1-{3-[(3-hydroxy-propylimino)methyl]-4-hydroxyphenylazo}-4-chloro-3-nitrobenzene (2c) were prepared. The ligands were characterized by elemental analysis, FTIR spectroscopy, UV-Vis spectroscopy, 13C- and 1H-NMR spectroscopy and thermogravimetric analysis. Next the corresponding copper(II) and cobalt(II) metal complexes were synthesized and characterized by the physicochemical and spectroscopic methods of elemental analysis, FTIR spectroscopy, UV-Vis spectroscopy, magnetic moment measurements, and thermogravimetric analysis (TGA) and (DSC). The room temperature effective magnetic moments of complexes are 1.45, 1.56, 1.62, 2.16, 2.26 and 2.80 B.M. for complexes 3a, 3b, 3c, 4a 4b, and 4c, respectively, indicating that the complexes are paramagnetic with considerable electronic communication between the two metal centers. |
Molecules, Vol. 17, Pages 6424-6433: Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne Posted: 29 May 2012 12:00 AM PDT Two new diterpenoids, wikstroelide Q (1) and prostratin Q (5), together with three known diterpenoids, pimelea factors P2 (2), P3 (3), and prostratin (4), and five known lignans, (+)-epipioresinol (6), (+)-isolariciresinol (7), (−)-lariciresinol (8), (+)-epi-sesaminone (9), and prestegane B (10), were isolated from the buds of Wikstroemia chamaedaphne Meissn. Their structures were elucidated by a combination of spectroscopic analyses. Compounds 1–10 were evaluated for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines in vitro. |
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Southern Highlands Honors Heroes on Memorial Day Posted: 29 May 2012 02:11 AM PDT From morning ceremonies to nighttime fireworks, America celebrated Memorial Day. |
Posted: 29 May 2012 12:00 AM PDT The formation of 1,3-diketones was observed in the reactions of bulky acyl chlorides with methyllithium. The reaction products depend on the steric hindrance around the carbonyl group of the acyl chloride and the electronic effect of the group(s) linked to the carbonyl. When the steric hindrance around the carbonyl group of the acyl chloride is big enough, the 1,3-diketone is the only product. In the case of the moderate hindrance around the carbonyl group of the acyl chloride, a moderate yield of 1,3-diketone is obtained and some tertiary alcohol is generated. When there is no steric hindrance around the carbonyl group of the acyl chloride, the tertiary alcohol is the only product. When the steric hindrance around the carbonyl group is moderate and an electron-donating group is connected to the carbonyl of the acyl chloride, all three products—ketone, 1,3-diketone and tertiary alcohol—can be isolated from the reaction mixture after long reaction times. |
Posted: 29 May 2012 12:00 AM PDT An indium nitride (InN) gas sensor of 10 nm in thickness has achieved detection limit of 0.4 ppm acetone. The sensor has a size of 1 mm by 2.5 mm, while its sensing area is 0.25 mm by 2 mm. Detection of such a low acetone concentration in exhaled breath could enable early diagnosis of diabetes for portable physiological applications. The ultrathin InN epilayer extensively enhances sensing sensitivity due to its strong electron accumulation on roughly 5–10 nm deep layers from the surface. Platinum as catalyst can increase output current signals by 2.5-fold (94 vs. 37.5 μA) as well as reduce response time by 8.4-fold (150 vs. 1,260 s) in comparison with bare InN. More, the effect of 3% oxygen consumption due to breath inhalation and exhalation on 2.4 ppm acetone gas detection was investigated, indicating that such an acetone concentration can be analyzed in air. |
Posted: 29 May 2012 12:00 AM PDT Magnetic Induction Tomography (MIT), which is also known as Electromagnetic Tomography (EMT) or Mutual Inductance Tomography, is among the imaging modalities of interest to many researchers around the world. This noninvasive modality applies an electromagnetic field and is sensitive to all three passive electromagnetic properties of a material that are conductivity, permittivity and permeability. MIT is categorized under the passive imaging family with an electrodeless technique through the use of excitation coils to induce an electromagnetic field in the material, which is then measured at the receiving side by sensors. The aim of this review is to discuss the challenges of the MIT technique and summarize the recent advancements in the transmitters and sensors, with a focus on applications in biological tissue imaging. It is hoped that this review will provide some valuable information on the MIT for those who have interest in this modality. The need of this knowledge may speed up the process of adopted of MIT as a medical imaging technology. |
Sensors, Vol. 12, Pages 7109-7125: Personal Pervasive Environments: Practice and Experience Posted: 29 May 2012 12:00 AM PDT In this paper we present our experience designing and developing two different systems to enable personal pervasive computing environments, Plan B and the Octopus. These systems were fully implemented and have been used on a daily basis for years. Both are based on synthetic (virtual) file system interfaces and provide mechanisms to adapt to changes in the context and reconfigure the system to support pervasive applications. We also present the main differences between them, focusing on architectural and reconfiguration aspects. Finally, we analyze the pitfalls and successes of both systems and review the lessons we learned while designing, developing, and using them. |
Posted: 29 May 2012 12:00 AM PDT We have successfully developed a surface plasmon resonance (SPR) measurement system for the on-site immunoassay of real samples. The system is composed of a portable SPR instrument (290 mm(W) x 160 mm(D) x 120 mm(H)) and a microfluidic immunoassay chip (16 mm(W) x 16 mm(D) x 4 mm(H)) that needs no external pump system. An integrated vertical capillary tube functions as a large volume (150 μL ) passive pump and a waste reservoir that has sufficient capacity for several refill operations. An immunoassay was carried out that employed the direct injection of a buffer and a test sample in sequence into a microfluidic chip that included 9 antibody bands and 10 reference reagent bands immobilized in the flow channel. By subtracting a reliable averaged reference sensorgram from the antibody, we effectively reduced the influence of the non-specific binding, and then our chip successfully detected the specific binding of spiked IgG in non-homogeneous milk. IgG is a model antigen that is certain not to be present in non-homogeneous milk, and non-homogeneous milk is a model of real sample that includes many interfering foreign substances that induce non-specific binding. The direct injection of a real sample with no pretreatment enabled us to complete the entire immunoassay in several minutes. This ease of operation and short measuring time are acceptable for on-site agricultural, environmentaland medical testing. |
Posted: 29 May 2012 12:00 AM PDT We show that a short mercury-specific aptamer (MSA) along with gold nanoparticles (Au-NPs) can be used to determine Hg(II) ion by a combination of a QCM-based sensor and a flow system. The MSA binds specifically to Hg(II), and the Au-NPs can amplify the signal to enhance sensitivity. Specifically, the short thiolated MSAs are immobilized on the surface of the QCM as the capture probe, and the MSAs are linked to the Au-NPs as the linking probe. The two components can form a sandwich structure of the T-Hg(II)-T type in the presence of Hg(II) ions. This leads to change in the mass on the QCM and a change in the resonance frequency. Hg(II) can be determined with a detection limit of 0.24 ± 0.06 nM which is better by three orders of magnitude than previous methods. The sensor can be regenerated by disrupting the T-Hg(II)-T base pairs with a solution of cysteine. |
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