Games |
- Say goodbye to one of 3DS' two launch models *sniff*
- BitNami MAPPStack 5.3.12-0 - Easy installation of Apache, PostgreSQL, PHP, and phpPgAdmin.. (Free)
- Disksomnia 3.0.1 - Stop external HDs from sleep, for Final Cut Pro/Express users.. (Commercial)
- Crazy Racoon
- Sensors, Vol. 12, Pages 6282-6306: An Approach for Representing Sensor Data to Validate Alerts in Ambient Assisted Living
- Sensors, Vol. 12, Pages 6269-6281: Wireless Biosensor System for Real-Time L-Lactic Acid Monitoring in Fish
- IJMS, Vol. 13, Pages 5740-5750: Gastroprotective Effect of Selenium on Ethanol-Induced Gastric Damage in Rats
- IJMS, Vol. 13, Pages 5729-5739: Ginsenoside Rg3 Reduces Lipid Accumulation with AMP-Activated Protein Kinase (AMPK) Activation in HepG2 Cells
- IJMS, Vol. 13, Pages 5715-5728: Immune Responses in Pigs Induced by Recombinant DNA Vaccine Co-Expressing Swine IL-18 and Membrane Protein of Porcine Reproductive and Respiratory Syndrome Virus
- IJMS, Vol. 13, Pages 5706-5714: Characterization of CdTe Films Deposited at Various Bath Temperatures and Concentrations Using Electrophoretic Deposition
- IJMS, Vol. 13, Pages 5700-5705: Development of Nine Markers and Characterization of the Microsatellite Loci in the Endangered Gymnogobius isaza (Gobiidae)
- F1: Surprising Alonso Leads First Spain Practice
- Wall Street Titan - Screenshots
- Punch Hero - Screenshots
- Zombie Punch
- Ninja Vs Zombie
- Lab Escape Race
- F1: Schumacher Eyes Return To Podium In Spain
- RelaunchFinder 1.0 - Launch the sidebar you want in Mac OS X 10.7.. (Free)
- Materials, Vol. 5, Pages 818-850: Investigating the Defect Structures in Transparent Conducting Oxides Using X-ray and Neutron Scattering Techniques
| Say goodbye to one of 3DS' two launch models *sniff* Posted: 11 May 2012 03:17 AM PDT
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| BitNami MAPPStack 5.3.12-0 - Easy installation of Apache, PostgreSQL, PHP, and phpPgAdmin.. (Free) Posted: 10 May 2012 09:00 PM PDT  BitNami MAPPStack is an easy to install software platform that greatly simplifies the deployment of Open Source web stacks on Mac OS X. It includes ready-to-run versions of Apache, PostgreSQL, PHP, phpPgAdmin and required dependencies and installs in minutes. Version 5.3.12-0:
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| Disksomnia 3.0.1 - Stop external HDs from sleep, for Final Cut Pro/Express users.. (Commercial) Posted: 11 May 2012 03:20 AM PDT  Disksomnia works seamlessly in the background to keep any disk awake, including those that ignore Energy Saver preferences, since wtexaiting for disks to wake up can be a frustrating experience for content creators who often work with media files located on multiple disks. Disksomnia 3.0 is an invisible application with negligible overhead so system performance will not be affected. Options for controlling when it runs and which disks it affects can be set in a new System Preferences pane.
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| Posted: 11 May 2012 03:21 AM PDT This raccoon has gone mad. He is hunting on bears, but not in a normal way. He has a gun! Shoot all the bears to finish each level. |
| Posted: 11 May 2012 12:00 AM PDT The mainstream of research in Ambient Assisted Living (AAL) is devoted to developing intelligent systems for processing the data collected through artificial sensing. Besides, there are other elements that must be considered to foster the adoption of AAL solutions in real environments. In this paper we focus on the problem of designing interfaces among caregivers and AAL systems. We present an alert management tool that supports carers in their task of validating alarms raised by the system. It generates text-based explanations—obtained through an argumentation process—of the causes leading to alarm activation along with graphical sensor information and 3D models, thus offering complementary types of information. Moreover, a guideline to use the tool when validating alerts is also provided. Finally, the functionality of the proposed tool is demonstrated through two real cases of alert. |
| Posted: 11 May 2012 12:00 AM PDT We have developed a wireless biosensor system to continuously monitor L-lactic acid concentrations in fish. The blood L-lactic acid level of fish is a barometer of stress. The biosensor comprised Pt-Ir wire (φ0.178 mm) as the working electrode and Ag/AgCl paste as the reference electrode. Lactate oxidase was immobilized on the working electrode using glutaraldehyde. The sensor calibration was linear and good correlated with L-lactic acid levels (R = 0.9959) in the range of 0.04 to 6.0 mg·dL−1. We used the eyeball interstitial sclera fluid (EISF) as the site of sensor implantation. The blood L-lactic acid levels correlated closely with the EISF L-lactic acid levels in the range of 3 to 13 mg·dL−1 (R = 0.8173, n = 26). Wireless monitoring of L-lactic acid was performed using the sensor system in free-swimming fish in an aquarium. The sensor response was stable for over 60 h. Thus, our biosensor provided a rapid and convenient method for real-time monitoring of L-lactic acid levels in fish. |
| Posted: 11 May 2012 12:00 AM PDT In the present study, we examined the gastroprotective effect of selenium against ethanol-induced gastric mucosal lesions in rats. The gastric mucosal lesions were produced by oral administration with various concentrations of ethanol for three days, and 80% ethanol treatment was determined to be the optimal condition for induction of gastric damage. To identify the protective effect of selenium on ethanol-induced gastric damage, various doses of selenium were given as pretreatment for three days, and then gastric damage was induced by 80% ethanol treatment. Selenium showed a protective effect against ethanol-induced gastric mucosal lesions in a dose dependent manner. Specifically, 100 μg/kg selenium showed the highest level of gastroprotection. In addition, selenium markedly attenuated ethanol-induced lipid peroxidation in gastric mucosa and increased activities of radical scavenging enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase in a dose-dependent manner. Histological data showed that 100 μg/kg selenium distinctly reduced the depth and severity of the ethanol induced gastric lesion. These results clearly demonstrate that selenium inhibits the formation of ethanol-induced gastric mucosal lesions through prevention of lipid peroxidation and activation of enzymatic radical scavenging. |
| Posted: 11 May 2012 12:00 AM PDT Cardiovascular disease (CVD) is one of the main causes of mortality worldwide, and dyslipidemia is a major risk factor for CVD. Ginseng has been widely used in the clinic to treat CVD. Ginsenoside Rg3, one of the major active components of ginseng, has been reported to exhibit antiobesity, antidiabetic, and cardioprotective effects. However, the effect of ginsenoside Rg3 on hepatic lipid metabolism remains unclear. Therefore, we investigated whether ginsenoside Rg3 would regulate hepatic lipid metabolism with AMP-activated protein kinase (AMPK) activation in HepG2 cells. Ginsenoside Rg3 significantly reduced hepatic cholesterol and triglyceride levels. Furthermore, ginsenoside Rg3 inhibited expression of sterol regulatory element binding protein-2 (SREBP-2) and 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMGCR). Ginsenoside Rg3 increased activity of AMPK, a major regulator of energy metabolism. These results suggest that ginsenoside Rg3 reduces hepatic lipid accumulation with inhibition of SREBP-2 and HMGCR expression and stimulation of AMPK activity in HepG2 cells. Therefore, ginsenoside Rg3 may be beneficial as a food ingredient to lower the risk of CVD by regulating dyslipidemia. |
| Posted: 11 May 2012 12:00 AM PDT In this study, two DNA vaccines, which express the membrane (M) protein of porcine respiratory and reproductive syndrome virus (PRRSV) (pEGFP-M) and co-express both M and swine IL-18 (pEGFP-IL18-M), were constructed and their abilities to induce humoral and cellular responses in piglets were comparatively evaluated. Experimental results showed that both recombinant DNA vaccines could not elicit neutralizing antibodies in the immunized piglets. However, both DNA vaccines elicited Th1-biased cellular immune responses. Notably, pigs immunized with the plasmid pEGFP-IL18-M developed significantly higher levels of IFN-γ and IL-2 production response and stronger specific T-lymphocyte proliferation response than the pigs inoculated with the plasmids pEGFP-M and pEGFP-IL18 (P < 0.05). These results illustrated that co-expression of M and IL-18 proteins could significantly improve the potency of DNA vaccination on the activation of vaccine-induced virus-specific cell-mediated immune responses in pigs, which may be used as a strategy to develop a new generation of vaccines against highly pathogenic PRRSV. |
| Posted: 11 May 2012 12:00 AM PDT CdTe film was deposited using the electrophoretic deposition technique onto an ITO glass at various bath temperatures. Four batch film compositions were used by mixing 1 to 4 wt% concentration of CdTe powder with 10 mL of a solution of methanol and toluene. X-ray Diffraction analysis showed that the films exhibited polycrystalline nature of zinc-blende structure with the (111) orientation as the most prominent peak. From the Atomic Force Microscopy, the thickness and surface roughness of the CdTe film increased with the increase of CdTe concentration. The optical energy band gap of film decreased with the increase of CdTe concentration, and with the increase of isothermal bath temperature. The film thickness increased with respect to the increase of CdTe concentration and bath temperature, and following, the numerical expression for the film thickness with respect to these two variables has been established. |
| Posted: 11 May 2012 12:00 AM PDT Gymnogobius isaza is a freshwater goby endemic to Lake Biwa, Japan. They experienced a drastic demographic bottleneck in the 1950s and 1980s and slightly recovered thereafter, but the population size is still very small. To reveal dynamics of genetic diversity of G. isaza, we developed nine microsatellite markers based on the sequence data of a related goby Chaenogobius annularis. Nine SSR (Simple Sequence Repeats) markers were successfully amplified for raw and formalin-fixed fish samples. The number of alleles and expected heterozygosities ranged from one to 10 and from 0.06 to 0.84, respectively, for the current samples, while one to 12 and 0.09 to 0.83 for historical samples. The markers described here will be useful for investigating the genetic diversity and gene flow and for conservation of G. isaza. |
| F1: Surprising Alonso Leads First Spain Practice Posted: 11 May 2012 12:00 AM PDT  Fernando Alonso took the surprisingly quick Ferrari to the top of the time sheet in FP1... |
| Wall Street Titan - Screenshots Posted: 11 May 2012 03:59 AM PDT The core game is a stress reliever for the 99% - a way to vent your frustration with "the man" and feel powerful by squashing the evil Wall Street bankers under your finger, as so many of us are under their thumbs. The game is also a platform for raising awareness about the economic, social, and political crises the world is facing right now. We strive to be strictly informational, as we feel everyone is intelligent enough to form their own opinions. What we are fighting is ignorance and apathy. |
| Posted: 11 May 2012 03:49 AM PDT ADRENALINE PUMPING BOXING ACTION! Deliver swift jabs, hooks, uppercuts and serve brutal knockout punches as you fight your opponent. CUSTOMIZE YOUR CHARACTER! Give yourself a gnarly beard or maybe some cool shades as you dress your character in the Costume Shop with items that enhance performance. INTENSE SKILL BUILDING IN THREE DIFFERENT MODES! Fight with new challengers in Arcade Mode, Amateur Mode and Pro Mode as you level up and hone your jabs, hooks and uppercuts. ADD YOUR OWN FACE! Throw your friend (or enemy) into the ring by creating your own challenger in Challenger Registry. Place their picture in the frame and fight them in the virtual ring. GAMECENTER ACHIEVEMENTS! Play in Graveyard Mode as your go 1 on 1 with all players or your friends through Gamecenter. |
| Posted: 11 May 2012 02:59 AM PDT Your High school has been taken over, its up to you to survive. Using only your fists you fight endless waves of zombie intruders. |
| Posted: 11 May 2012 02:59 AM PDT Help this ninja fight off these brain eating zombies. Use your Shurikens to wipe them out in each level. Good Luck! |
| Posted: 11 May 2012 02:59 AM PDT Drive in a monster truck on a parkour with large hills and several obstacles. Beware that you don't crash. |
| F1: Schumacher Eyes Return To Podium In Spain Posted: 11 May 2012 12:00 AM PDT  Michael Schumacher has seven wins at Spain's Catalunya Circuit... |
| RelaunchFinder 1.0 - Launch the sidebar you want in Mac OS X 10.7.. (Free) Posted: 11 May 2012 01:58 AM PDT  RelaunchFinder relaunches the Finder directly after logging in / starting up to enable the colorful sidebar. Maybe you didn't like the grey Sidebar icons in Mac OS X 10.7? Chances are you installed SIMBL Colorful Sidebar to try and fix it. Maybe you recall there was an issue: you had to relaunch the Finder after logging in. The app has been rewritten and updated (no longer a WorkFlow app), and It has been packaged into an installer which handles the dirty work of enabling it. Version 1.0: The new installer will:
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| Posted: 11 May 2012 12:00 AM PDT Transparent conducting oxide (TCO) materials are implemented into a wide variety of commercial devices because they possess a unique combination of high optical transparency and high electrical conductivity. Created during the processing of the TCOs, defects within the atomic-scale structure are responsible for their desirable optical and electrical properties. Therefore, studying the defect structure is essential to a better understanding of the behavior of transparent conductors. X-ray and neutron scattering techniques are powerful tools to investigate the atomic lattice structural defects in these materials. This review paper presents some of the current developments in the study of structural defects in n-type TCOs using x-ray diffraction (XRD), neutron diffraction, extended x-ray absorption fine structure (EXAFS), pair distribution functions (PDFs), and x-ray fluorescence (XRF). |
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