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- Sensors, Vol. 12, Pages 9467-9475: A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb2+) Detection
- ProtectMac AntiVirus 1.3 - Keeps you safe from viruses and spyware.. (Demo)
- nessMediaCenter 1.0 - Make your Mac an optimal media center.. (Demo)
- ActioM Personal 1.1 - Organize and prioritize your actions list.. (Shareware)
- MuteMyMic 1.9 - Control selected input volume from your status bar.. (Commercial)
- Agronomy, Vol. 2, Pages 167-186: N2O Emission and Mineral N Release in a Tropical Acrisol Incorporated with Mixed Cowpea and Maize Residues
- Toxins, Vol. 4, Pages 536-553: Bacillus anthracis Factors for Phagosomal Escape
- Energies, Vol. 5, Pages 2381-2403: Parametric Study of Thermodynamics in the Mediterranean Courtyard as a Tool for the Design of Eco-Efficient Buildings
- Entropy, Vol. 14, Pages 1221-1233: Nonparametric Estimation of Information-Based Measures of Statistical Dispersion
- Genes, Vol. 3, Pages 391-408: siRNAs Trigger Efficient Silencing of a Parasitism Gene in Plant Parasitic Root-Knot Nematodes
- Agriculture, Vol. 2, Pages 154-164: Purification and Phytotoxic Analysis of Botrytis cinerea Virulence Factors: New Avenues for Crop Protection
- IJERPH, Vol. 9, Pages 2444-2453: Secondary Leukemia Associated with the Anti-Cancer Agent, Etoposide, a Topoisomerase II Inhibitor
- Atmosphere, Vol. 3, Pages 288-319: Assessment of the Weather Research and Forecasting/Chemistry Model to Simulate Ozone Concentrations in March 2008 over Coastal Areas of the Sea of Japan
- Suspicious Package 1.3 - Quick Look plugin to preview contents of installer packages.. (Free)
- Comic-Con 2012 360 Costume Cam
- Rockstar expands its Toronto operations
- Super Monkey Ball 2: Sakura Edition for iPad Screens
- InstantChess Screens
- BattleSweeper Screens
- Paddle Fighter Screens
| Posted: 10 Jul 2012 12:00 AM PDT A portable and power-free microfluidic device was designed for rapid and sensitive detection of lead (Pb2+). 11-mercaptoundecanoic acid (MUA)-functionalized gold nanoparticles (MUA-AuNPs) aggregated in the presence of Pb2+ for the chelation mechanism. When we performed this analysis on a polydimethylsiloxane (PDMS) microfluidic chip, the aggregations deposited onto the surface of chip and formed dark lines along the laminar flows in the zigzag microchannels. This visual result can be observed by the naked eye through a microscope or just a drop of water as a magnifier. Ten μM Pb2+ was successfully detected. |
| ProtectMac AntiVirus 1.3 - Keeps you safe from viruses and spyware.. (Demo) Posted: 10 Jul 2012 02:50 AM PDT  ProtectMac AntiVirus ... The next generation security product for Mac OS X, designed to keep you safe from viruses and spyware. ProtectMac AntiVirus allows you to scan any area of your Mac or network for both Macintosh and Non-Macintosh malware. The user-friendly, graphical interface enables you to perform user scans, set up scheduled scans to run in the background, monitor status information and manage any threats that are discovered. ProtectMac AntiVirus automatically checks for updates daily, downloading new threat identities and product updates and installing them without user intervention or the need to restart your Mac. At the heart of the product is a file-access scanner that is always running in the background in real-time checking for threats, intercepting every file that is opened, closed or copied, any application that is launched, any file that is downloaded from the internet or email attachment that is extracted. With the ability to scan any device or location directly from Finder's contextual menu, as well as automatic scanning of DVDs, CDs, USB devices and DMG files as they are mounted, checking for threats on your Mac has never been easier!
Mac OS X 10.4.7 or later. Download Now This posting includes an audio/video/photo media file: Download Now |
| nessMediaCenter 1.0 - Make your Mac an optimal media center.. (Demo) Posted: 10 Jul 2012 02:44 AM PDT  nessMediaCenter enables you to use your Mac as optimal media center! Internet offers, Aperature and iPhoto albums, iTunes music, Miro video podcasts, local media at picture/movie folder and volumes can be selected easily & comfortably. Plenty of different media can be selected and will be continuously presented afterwards. MediaCenter and media presentations can be controlled by keyboard or Apple remote control. Home entertainment as its purest - comfortable and relaxing, from the couch, armchair, bed or directly at the Apple computer!
Download Now This posting includes an audio/video/photo media file: Download Now |
| ActioM Personal 1.1 - Organize and prioritize your actions list.. (Shareware) Posted: 10 Jul 2012 02:35 AM PDT  ActioM Personal is an actions list manager for Mac OS X 10.7. Its sober design is conceived for simple and effective use. With its elegant interface and pleasant to use, ActioM Personal provides all functions to capture, organize and remember all the things you have to do. You can add a description to each action, assign them a priority and due date. Each action can be organized according to subjects of your choice, with the possibility to combine several subjects in each action. Filter the view of the actions to see only those of a given subject, view all or choose those that do not matter. You can sort the actions in order of creation, deadline or alphabetically. ActioM allows you to quickly see the important actions or delay. Version 1.1: Release notes were unavailable when this listing was updated. Mac OS X 10.7 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| MuteMyMic 1.9 - Control selected input volume from your status bar.. (Commercial) Posted: 10 Jul 2012 02:24 AM PDT  MuteMyMic provides you with an easy way to control Input Volume from the status bar or via keyboard shortcuts. Keyboard shortcuts:
There is a new feature - "force mute". Whenever MuteMyMic determines that microphone was unmuted it will mute it again (this feature can be enabled/disable via Preferences panel). Version 1.9: Note: the download is for Version 1.7.1. Version 1.9 is available for purchase through the Mac App Store.
Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 10 Jul 2012 12:00 AM PDT A laboratory microcosm incubation was conducted to study the influence of mixed cowpea-maize residues on N2O emission and N mineralization in a tropical acrisol. The soils were incorporated with different ratios of cowpea:maize mixtures on weight basis: 100:0, 75:25, 50:50, 25:75 and 0:100, and a control treatment in which there was no residue incorporation. The results show that N2O and CO2 emissions were higher in the sole cowpea treatment (100:0) than the sole maize treatment (0:100) and the control. However, cowpea-maize residue mixtures increased the proportion of N lost as N2O compared to the sole treatments. This interactive effect was highest in the 75:25 treatment. The 50:50 treatment showed moderate N2O emission compared to the 100:0, 75:25 and 25:75 treatments but with corresponding steady N mineralization and appreciable mineral N concentration. It is concluded that mixing cowpea-maize residues might increase the proportion of N lost as N2O in a tropical acrisol. However, compared to the other residue mixture treatments, mixing cowpea-maize residues in equal proportions on weight basis might offer a path to reducing N2O emissions while maintaining a steady N mineralization without risking good N supply in acrisols. The study therefore offers potential for mitigating greenhouse gas emissions while maintaining soil fertility in tropical acrisols. However, further studies under both laboratory and field conditions will be required to verify and validate this claim. |
| Toxins, Vol. 4, Pages 536-553: Bacillus anthracis Factors for Phagosomal Escape Posted: 10 Jul 2012 12:00 AM PDT The mechanism of phagosome escape by intracellular pathogens is an important step in the infectious cycle. During the establishment of anthrax, Bacillus anthracis undergoes a transient intracellular phase in which spores are engulfed by local phagocytes. Spores germinate inside phagosomes and grow to vegetative bacilli, which emerge from their resident intracellular compartments, replicate and eventually exit from the plasma membrane. During germination, B. anthracis secretes multiple factors that can help its resistance to the phagocytes. Here the possible role of B. anthracis toxins, phospholipases, antioxidant enzymes and capsules in the phagosomal escape and survival, is analyzed and compared with that of factors of other microbial pathogens involved in the same type of process. |
| Posted: 10 Jul 2012 12:00 AM PDT Traditionally, people in the Mediterranean region knew that the temperatures in their courtyards were cooler in summer than outside temperature. This paper provides a quantitative study on the usefulness of Mediterranean courtyards as passive energy saving systems. This work is based on the creation of a Computational Fluid Dynamics (CFD) numerical model developed using the open source Freefem++ language. In this work, first the numerical model is tested using simplified-shape courtyards which have been previously studied both physically under controlled parameters, and mathematically through numerical simulations. We also study the most appropriate depth ratio for a courtyard, based on these simplified shapes, depending on the climate. Secondly, we apply the numerical model in a real geometry, the Monte Málaga hotel. We compare the numerical results with the monitored data of the temperature in the courtyard of the hotel. The numerical model takes into account precomputed solar radiation in the walls of the courtyard, the predominant wind and buoyancy effects. |
| Posted: 10 Jul 2012 12:00 AM PDT We address the problem of non-parametric estimation of the recently proposed measures of statistical dispersion of positive continuous random variables. The measures are based on the concepts of differential entropy and Fisher information and describe the "spread" or "variability" of the random variable from a different point of view than the ubiquitously used concept of standard deviation. The maximum penalized likelihood estimation of the probability density function proposed by Good and Gaskins is applied and a complete methodology of how to estimate the dispersion measures with a single algorithm is presented. We illustrate the approach on three standard statistical models describing neuronal activity. |
| Posted: 10 Jul 2012 12:00 AM PDT Expanding genomic data on plant pathogens open new perspectives for the development of specific and environment friendly pest management strategies based on the inhibition of parasitism genes that are essential for the success of infection. Identifying such genes relies on accurate reverse genetics tools and the screening of pathogen knock-down phenotypes. Root-knot nematodes are major cosmopolitan crop pests that feed on a wide range of host plants. Small interfering RNAs (siRNAs) would provide a powerful tool for reverse genetics of nematode parasitism genes provided that they could (1) target genes expressed in inner tissues of infective nematodes and (2) target genes expressed during parasitism. In this study, we show that siRNAs can access inner tissues of the infective juveniles during soaking and accumulate in the esophagus, amphidial pouches and related neurons of the nematode. We provide evidence that siRNAs can trigger knock-down of the parasitism gene Mi-CRT, a calreticulin gene expressed in the esophageal glands of Meloidogyne incognita. Mi-CRT knock-down in infective juveniles affected nematode virulence. However, Mi-CRT knock-down was not persistent after plant infection, indicating that siRNA-mediated RNAi is best suited for functional analysis of genes involved in pre-parasitic stages or in the early steps of infection. |
| Posted: 10 Jul 2012 12:00 AM PDT Botrytis cinerea is a necrotrophic fungus infecting over 230 plant species worldwide. This highly adaptable pathogen can afflict agricultural products from seed to storage, causing significant economic losses and instability in the food supply. Small protein virulence factors secreted by B. cinerea during infection play an important role in initiation and spread of disease. BcSnod1 was found to be abundantly expressed upon exposure to media containing strawberry extract. From sequence similarity, BcSnod2 was also identified and both were recognized as members of the Ceratoplatanin family of small phytotoxic proteins. Recombinant BcSnod1 was shown to have a phytotoxic effect and play an important role in pathogenicity while the role of BcSnod2 remains less clear. Both bacterial and yeast production systems are reported, though the bacterial protein is less toxic and mostly unfolded relative to that made in yeast. Compared to BcSnod1, recombinant bacterial BcSnod2 shows similar, but delayed phytotoxicity on tomato leaves. Further studies of these critical virulence factors and their inhibition promise to provide new avenues for crop protection. |
| Posted: 10 Jul 2012 12:00 AM PDT Etoposide is an anticancer agent, which is successfully and extensively used in treatments for various types of cancers in children and adults. However, due to the increases in survival and overall cure rate of cancer patients, interest has arisen on the potential risk of this agent for therapy-related secondary leukemia. Topoisomerase II inhibitors, including etoposide and teniposide, frequently cause rearrangements involving the mixed lineage leukemia (MLL) gene on chromosome 11q23, which is associated with secondary leukemia. The prognosis is extremely poor for leukemias associated with rearrangements in the MLL gene, including etoposide-related secondary leukemias. It is of great importance to gain precise knowledge of the clinical aspects of these diseases and the mechanism underlying the leukemogenesis induced by this agent to ensure correct assessments of current and future therapy strategies. Here, I will review current knowledge regarding the clinical aspects of etoposide-related secondary leukemia, some probable mechanisms, and strategies for treating etoposide-induced leukemia. |
| Posted: 10 Jul 2012 12:00 AM PDT The fully coupled WRF/Chem (Weather Research and Forecasting/Chemistry) model is used to simulate air quality over coastal areas of the Sea of Japan. The anthropogenic surface emissions database used as input for this model was based primarily on global hourly emissions data (dust, sea salt, and biomass burning), RETRO (REanalysis of the TROpospheric chemical composition), GEIA (Global Emissions Inventory Activity), and POET (Precursors of Ozone and their Effects in the Troposphere). Climatologic concentrations of particulate matter derived from the Regional Acid Deposition Model (RADM2), chemical mechanism, and the Secondary Organic Aerosol Model (MADE/SORGAM) with aqueous reactions were used to deduce the corresponding aerosol fluxes for input to the WRF/Chem model. The model was first integrated continuously over 48 hours, starting from 00:00 UTC on 14 March 2008, to evaluate ozone concentrations and other precursor pollutants. WPS meteorological data were used for the WRF/Chem model simulation in this study. Despite the low resolution of global emissions and the weak density of the local point emissions, it was found that the WRF/Chem model simulates the diurnal variation of the chemical species concentrations over the coastal areas of the Sea of Japan quite well. The Air Quality Management Division of the Ministry of the Environment in Japan selected the maximum level of the air quality standard for ozone, which is 60 ppb. In this study, the atmospheric concentrations of ozone over the coastal area of the Sea of Japan were calculated to be 30–55 ppb during the simulation period, which was lower than the Japanese air quality standard for ozone. |
| Suspicious Package 1.3 - Quick Look plugin to preview contents of installer packages.. (Free) Posted: 10 Jul 2012 02:18 AM PDT  Suspicious Package allows you to preview the contents of a standard Apple installer package without launching the Installer. Just select the icon in the Finder and select Quick Look. You can click individual folder names to see their contents, or click the Show Contents button to see all content at once. Version 1.3:
Mac OS X 10.6 or later. Download Now This posting includes an audio/video/photo media file: Download Now |
| Comic-Con 2012 360 Costume Cam Posted: 09 Jul 2012 06:19 PM PDT Costumes and cosplay are to Comic-Con as peanut butter is to jelly or Cloud is to Sephiroth--they're inseparable. Take a look at some of the costumes of Comic-Con 2012 like never before with the 360 Costume Cam, brought to you by IE9! Get the full article at GameSpot "Comic-Con 2012 360 Costume Cam" was posted by Staff on Mon, 09 Jul 2012 18:19:21 -0700 |
| Rockstar expands its Toronto operations Posted: 09 Jul 2012 05:13 PM PDT Rockstar's Vancouver studio will be gradually moved to a new, larger facility in Oakville, Ontario; studio expansion is being supported by the Ontario Government.
Rockstar Games will be expanding its development efforts in Toronto with the opening of a larger studio in Oakville, Ontario.
The new facility will house the current Rockstar Toronto team, as well as the 35-person Rockstar Vancouver team, which will move to the new quarters gradually over the next six months. The publisher said it will offer all existing members of the Vancouver team the opportunity to join Rockstar Toronto or take positions in other Rockstar studios. According to the publisher, the new Toronto studio expansion is being financially supported by the Ontario Government; however, no financial details have been disclosed. "We believe a single Canadian team will make for a powerful creative force on future projects," Rockstar vice president of publishing and operations Jennifer Kolbe said. "We plan to add more than 50 new positions to our combined Canadian team, and are pleased to be entering into this strategic partnership with the Ontario Government." Rockstar Toronto has worked on several titles for the publisher, including Max Payne 3, The Warriors and the Grand Theft Auto series. Rockstar Vancouver has worked on Bully and Max Payne 3. Read and Post Comments | Get the full article at GameSpot "Rockstar expands its Toronto operations" was posted by Laura Parker on Mon, 09 Jul 2012 17:13:32 -0700 |
| Super Monkey Ball 2: Sakura Edition for iPad Screens Posted: 09 Jul 2012 04:49 PM PDT 1 new shots posted.
Get the full article at GameSpot "Super Monkey Ball 2: Sakura Edition for iPad Screens" was posted on Mon, 09 Jul 2012 16:49:02 -0700 |
| Posted: 09 Jul 2012 04:46 PM PDT 5 new shots posted.
Get the full article at GameSpot "InstantChess Screens" was posted on Mon, 09 Jul 2012 16:46:39 -0700 |
| Posted: 09 Jul 2012 04:45 PM PDT 2 new shots posted.
Get the full article at GameSpot "BattleSweeper Screens" was posted on Mon, 09 Jul 2012 16:45:40 -0700 |
| Posted: 09 Jul 2012 04:45 PM PDT 5 new shots posted.
Get the full article at GameSpot "Paddle Fighter Screens" was posted on Mon, 09 Jul 2012 16:45:38 -0700 |
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