Games |
- RevolverHD 2.2.0 - Playback edited high definition movies on Playstation3.. (Demo)
- Toxins, Vol. 4, Pages 580-604: Molecular Motions as a Drug Target: Mechanistic Simulations of Anthrax Toxin Edema Factor Function Led to the Discovery of Novel Allosteric Inhibitors
- Icy Tower - Screenshots
- Maia Preview: Mostly Harmful
- Voltaic 3.1.0 - Convert AVCHD movie clips into a Mac-friendly format (aka VoltaicHD).. (Demo)
- CaliBrate 1.8.2 - Create and batch process iCal events.. (Shareware)
- IJERPH, Vol. 9, Pages 2715-2727: Identification of the Appropriate Boundary Size to Use When Measuring the Food Retail Environment Surrounding Schools
- IJERPH, Vol. 9, Pages 2694-2714: Non-Genomic Effects of Xenoestrogen Mixtures
- Molecules, Vol. 17, Pages 9090-9103: Synthesis of New Phosphorus-Containing (Co)Polyesters Using Solid-Liquid Phase Transfer Catalysis and Product Characterization
- Legend of the Cryptids - Screenshots
- Finger Olympic - Screenshots
- Zombie Run HD - Screenshots
- Molecules, Vol. 17, Pages 9081-9089: Effects of Vitamin D Treatment on Skeletal Muscle Histology and Ultrastructural Changes in a Rodent Model
- Molecules, Vol. 17, Pages 9070-9080: Evaluation of the Pharmacological Function of Ulinastatin in Experimental Animals
- Sync Folders Pro 1.3 - Automatically sync any number of folders.. (Commercial)
- DOTA 2 Diaries - Part 3
- Profile Leveling Reveal!
- Changes to the GameSpot user leveling system
- The OzSpot 31/07/12: New Aussie studios, second-hand games
- Orc: Vengeance Review
| RevolverHD 2.2.0 - Playback edited high definition movies on Playstation3.. (Demo) Posted: 31 Jul 2012 03:22 AM PDT  RevolverHD allows you to playback your edited high definition movies from iMovie08 and Final Cut on the Playstation3. Also create Blu-ray compatible DVDs containing AVCHD content. Version 2.2.0:
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| Posted: 31 Jul 2012 12:00 AM PDT Edema Factor (EF) is a component of Bacillus anthracis toxin essential for virulence. Its adenylyl cyclase activity is induced by complexation with the ubiquitous eukaryotic cellular protein, calmodulin (CaM). EF and its complexes with CaM, nucleotides and/or ions, have been extensively characterized by X-ray crystallography. Those structural data allowed molecular simulations analysis of various aspects of EF action mechanism, including the delineation of EF and CaM domains through their association energetics, the impact of calcium binding on CaM, and the role of catalytic site ions. Furthermore, a transition path connecting the free inactive form to the CaM-complexed active form of EF was built to model the activation mechanism in an attempt to define an inhibition strategy. The cavities at the surface of EF were determined for each path intermediate to identify potential sites where the binding of a ligand could block activation. A non-catalytic cavity (allosteric) was found to shrink rapidly at early stages of the path and was chosen to perform virtual screening. Amongst 18 compounds selected in silico and tested in an enzymatic assay, 6 thiophen ureidoacid derivatives formed a new family of EF allosteric inhibitors with IC50 as low as 2 micromolars. |
| Posted: 31 Jul 2012 04:15 AM PDT FEATURES: • Help Harold and his friends climb up to 4 different towers o Icy Tower o Skyscraper o Clock Tower o Power Tower • Choose between 5 different avatars to play as o Harold the Homeboy o Wild Wendy o Disco Dave o Skating Scott o Rick Recruit • Tilt your phone and tap the screen to jump • The faster you run the higher you jump • Make your avatar do double or triple jumps to activate the combo mode and gain extra points • Sign into Facebook connect to share scores • 27 in-game achievements |
| Posted: 31 Jul 2012 03:31 AM PDT Simon Roth has been building worlds for quite some time now. It seems he has a talent for crafting game engines, for coding procedural generation routines and for modelling complex systems. This posting includes an audio/video/photo media file: Download Now |
| Voltaic 3.1.0 - Convert AVCHD movie clips into a Mac-friendly format (aka VoltaicHD).. (Demo) Posted: 31 Jul 2012 03:13 AM PDT  Voltaic (also known as VoltaicHD) converts your AVCHD movie clips into a Mac-friendly format, ready for editing in iMovie (HD and 08)and Final Cut Express/Pro. Version 3.1.0:
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| CaliBrate 1.8.2 - Create and batch process iCal events.. (Shareware) Posted: 31 Jul 2012 03:00 AM PDT  CaliBrate allows you to create and batch process Calendar (iCal) events.
Version 1.8.2:
Mac OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 31 Jul 2012 12:00 AM PDT This study included 6,971 students in grades 9 and 10 (ages 13 to 16 years) from 158 schools who participated in the 2009/2010 Health Behaviour in School-aged Children Study. Students provided information on where they typically ate lunch. The number of food retailers was obtained for six road network buffer sizes (500, 750, 1,000, 1,500, 2,000, and 5,000 meters) surrounding schools. Associations between the presence of food retailers near schools and students' lunchtime eating behaviours were examined using multilevel logistic regression. Comparisons of model fit statistics indicated that the 1,000 m buffer provided the best fit. At this distance, students with ≥3 food retailers near their schools had a 3.42 times greater relative odds (95% CI: 2.12–5.52) of eating their lunchtime meal at a food retailer compared to students with no nearby food retailers. Students who had ≥2 food retailers within 750 m of their schools had a 2.74 times greater relative odds (95% CI: 1.75–4.29), while those who had ≥1 food retailer within 500 m of their schools had 2.27 times greater relative odds of eating at food retailer (95% CI: 1.46–3.52) compared to those with no nearby food retailers. For distances greater than 1,000 m, no consistent relationships were found. |
| IJERPH, Vol. 9, Pages 2694-2714: Non-Genomic Effects of Xenoestrogen Mixtures Posted: 31 Jul 2012 12:00 AM PDT Xenoestrogens (XEs) are chemicals derived from a variety of natural and anthropogenic sources that can interfere with endogenous estrogens by either mimicking or blocking their responses via non-genomic and/or genomic signaling mechanisms. Disruption of estrogens' actions through the less-studied non-genomic pathway can alter such functional end points as cell proliferation, peptide hormone release, catecholamine transport, and apoptosis, among others. Studies of potentially adverse effects due to mixtures and to low doses of endocrine-disrupting chemicals have recently become more feasible, though few so far have included actions via the non-genomic pathway. Physiologic estrogens and XEs evoke non-monotonic dose responses, with different compounds having different patterns of actions dependent on concentration and time, making mixture assessments all the more challenging. In order to understand the spectrum of toxicities and their mechanisms, future work should focus on carefully studying individual and mixture components across a range of concentrations and cellular pathways in a variety of tissue types. |
| Posted: 31 Jul 2012 12:00 AM PDT This paper is directed towards the development of safe, and thermally stable solid polymer electrolytes. Linear phosphorus-containing (co)polyesters are described, including their synthesis, thermal analysis, conductivity, and non-flammability. Polycondensation of phenylphosphonic dichloride (PPD) with poly(ethylene glycol) (PEG 12000) with and without bisphenol A (BA) was carried out using solid-liquid phase transfer catalysis. Potassium phosphate is used as base. Yields in the range of 85.0–88.0%, and inherent viscosities in the range of 0.32–0.58 dL/g were obtained. The polymers were characterized by gel permeation chromatography, FT-IR, 1H- and 31P-NMR spectroscopy and thermal analysis. Their flammability was investigated by measuring limiting oxygen index values. The polymers are flame retardants and begin to lose weight in the 190 °C–231 °C range. Solid phosphorus- containing (co)polyesters were complexed with lithium triflate and the resulting ionic conductivity was determined. Conductivities in the range of 10−7–10−8 S cm−1 were obtained. |
| Legend of the Cryptids - Screenshots Posted: 31 Jul 2012 03:35 AM PDT Features: - 300+ glamorous and beautiful creature cards and create the most powerful team of your own! - Train Cryptids, and challenge other players to 'Battles'! - 25+ fantastic areas of the fantasy world to explore! - 100+ quests added in every EVENT. - Collect and steal Treasure from other players before they will take yours! - Work together with other Heroes, and create the world's best 'Guild'! - Invite friends and make your guild even stronger! - Full-color visuals and dazzling animations! - Original fantasy music soundtrack! - And much more!! |
| Posted: 31 Jul 2012 03:22 AM PDT You will play as "DIGIT", the leading character that challenges 4 funny finger opponents Thumby, Pinky, Yubi and Toe, they are the "finger" athletes who compete for the Gold medal in the most demanding Olympic games for your fingers. Run as fast as you can by tapping rapidly on your device's screen but be wise in your strategy making use of your energy. FingerOlympic lets you share your best marks with your friends on Twitter & Facebook! Also GameCenter Support to compete with "fingers" athletes from around the world. Experience the thrill of competition your fingers can bring! Take the challenge and win! |
| Posted: 31 Jul 2012 03:29 AM PDT Featuring: - Brainless controls! - 9 Unique characters! - NEW The Unbrave One zombie! - Jaw-dropping graphics! - Lot of fun! |
| Posted: 31 Jul 2012 12:00 AM PDT Vitamin D is well known for its role in maintaining calcium and phosphorus homeostasis and in promoting bone mineralization; however, more of its pleiotropic effects have been described recently. The aim of the present investigation was to study the effect of vitamin D treatment on skeletal muscles changes under different dietary conditions using an animal model. Four groups of C57BL/6J mice (n = 11 each) were maintained on either low fat diet (LFD) or high fat diet (HFD) with and without 1α,25–dihydroxyvitamin D3 (calcitriol) for 16 weeks. Animal weigh was recorded at baseline and then regular intervals, and at the end of the study, skeletal muscle tissues were harvested for the evaluation of the histopathological and ultrastructural changes. When control C57BL/6J mice were fed high-fat diet for 12 weeks, body weight gain was significantly increased compared with mice fed a LFD. (30.2% vs. 8.4%, p < 0.01). There was a significant gradual decrease in the weight of HFD fed mice that were treated with vitamin D as compared with a steady increase in the weights of controls (6.8% vs. 28.7%, p < 0.01). While the LFD group showed some ultrastructural changes, HDF fed on mice showed great muscle structural abnormalities. The whole sarcosome along with its membrane and cristae were severely damaged with scattered myocytes in HFD group. Furthermore, the mitochondria appeared weak and were on the verge of degenerations. The bands were diminished with loss of connections among myofibrils. These changes were attenuated in the HFD group treated with vitamin D with tissues have regained their normal structural appearance. The current findings indicate an important effect of vitamin D on skeletal muscle histology under HFD conditions. |
| Posted: 31 Jul 2012 12:00 AM PDT Organ protection is a routine therapy in severe injuries. Our aim was to evaluate the beneficial effects of ulinastatin in experimental rats. Rats were randomly divided into a sham control, a model control and an ulinastatin-treated group. Malondialdehyde (MDA) and superoxide dismutase (SOD) levels were determined. Serum amylase, serum aspartate aminotransaminase (AST), lactate dehydrogenase (LDH) and creatine kinase isoenzyme (CKMD) activities, interleukin-8 (IL-8), tumor necrosis factor-α (TNF-α), nitric oxide (NO) and cardiac troponin I (nTnl) levels were examined. Results showed that ulinastatin decreased MDA levels and ameliorated the down-regulation of SOD activity. In addition, ulinastatin pretreatment may decrease serum AST, LDH and CKMD activities, IL-8, TNF-α, and nTnl levels, and enhance NO level. Our results demonstrated that oxidative injury occurred after IR and that ulinastatin exhibits significant protective effects against these effects. |
| Sync Folders Pro 1.3 - Automatically sync any number of folders.. (Commercial) Posted: 30 Jul 2012 11:41 PM PDT  Sync Folders Pro synchronizes any number of folders on the fly at the same time when there are changes, or connecting external drives at a set time or manually.The application synchronizes folders with or without filter for folder names and / or file names. The Sync Folders Pro is perfect for backing up to USB, memory cards, disks on remote computers on your network. Install the VPN Server Configurator and you can synchronize folders on a remote Mac from anywhere in the world! Learn more at www.greenworldsoft.com. Features:
Version 1.1.5: Please Note: A free upgrade to version 1.3 is available via the 'Download Update' link above.
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| Posted: 30 Jul 2012 11:22 PM PDT Zorine throws Ed into his first 5v5 co-op bot match and with a little help from their friends, attempts to teach him about what it means to work and communicate effectively in a DOTA team. How many times will he let them down?
Read and Post Comments | Get the full article at GameSpot "DOTA 2 Diaries - Part 3" was posted by edmondt on Mon, 30 Jul 2012 23:22:24 -0700 |
| Posted: 30 Jul 2012 06:14 PM PDT How to achieve profile levels revealed. Get the full article at GameSpot "Profile Leveling Reveal! " was posted on Mon, 30 Jul 2012 18:14:56 -0700 |
| Changes to the GameSpot user leveling system Posted: 30 Jul 2012 06:14 PM PDT After a number of years of what was quite frankly a broken user leveling system, we've made some changes. Find out more! Get the full article at GameSpot "Changes to the GameSpot user leveling system" was posted by Lark Anderson on Mon, 30 Jul 2012 18:14:13 -0700 |
| The OzSpot 31/07/12: New Aussie studios, second-hand games Posted: 30 Jul 2012 06:06 PM PDT In this week's OzSpot we look how two of Australia's biggest mobile developers joined forces; plus: what was the top-selling video game in Australia this year?
Get the full article at GameSpot "The OzSpot 31/07/12: New Aussie studios, second-hand games" was posted by Laura Parker on Mon, 30 Jul 2012 18:06:53 -0700 |
| Posted: 30 Jul 2012 05:44 PM PDT Orc: Vengeance is an engrossing dungeon-crawler wrapped up in some beautifully detailed visuals.
Score: 7.5 / good Get the full article at GameSpot "Orc: Vengeance Review" was posted by Chris Schilling on Mon, 30 Jul 2012 17:44:41 -0700 |
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