Games |
- Minecraft - Videos and Trailers
- Mini Golf 3D - Videos and Trailers
- South Park - Tenorman's Revenge - Videos and Trailers
- First Contact Spaceport
- Crusade 2
- Sushi Bar Express - Screenshots
- Chester - Screenshots
- SurgeMail 60a4 - Easy to install and manage mail server.. (Shareware)
- A Better Finder Rename 9.02 - File, photo, and MP3 batch renamer.. (Shareware)
- TerraRay 6.5.1 - Create realistic landscape images.. (Demo)
- Pokemon champion stripped of his title after alleged 'poo fight' in hotel
- Molecules, Vol. 17, Pages 2833-2854: IMB2026791, a Xanthone, Stimulates Cholesterol Efflux by Increasing the Binding of Apolipoprotein A-I to ATP-Binding Cassette Transporter A1
- Molecules, Vol. 17, Pages 2823-2832: A Convenient Route to 4-Carboxy-4-Anilidopiperidine Esters and Acids
- Marine Drugs, Vol. 10, Pages 604-616: Fucoxantin: A Treasure from the Sea
- Symmetry, Vol. 4, Pages 225-250: Classical Knot Theory
- Energies, Vol. 5, Pages 621-657: A General Probabilistic Forecasting Framework for Offshore Wind Power Fluctuations
- Browser 1.1 - WebKit-based browser.. (Free)
- Entropy 1.4.1 - Versatile and easy to use archiver.. (Shareware)
- Mini Golf 3D - Screenshots
- Omerta - City of Gangsters - Screenshots
Minecraft - Videos and Trailers Posted: 07 Mar 2012 03:19 AM PST Official Minecraft trailer. |
Mini Golf 3D - Videos and Trailers Posted: 07 Mar 2012 03:12 AM PST Mini Golf 3D trailer. |
South Park - Tenorman's Revenge - Videos and Trailers Posted: 07 Mar 2012 02:56 AM PST Teaser trailer. |
Posted: 07 Mar 2012 03:48 AM PST You will be sent into space, but something strange happens way you get rid of the spaceship and you need to find another way to see your spaceship b.. |
Posted: 07 Mar 2012 03:48 AM PST We now bring Crusade 2! Destroy the buildings for victory. You also can create your own levels and share them with your friends. |
Sushi Bar Express - Screenshots Posted: 07 Mar 2012 03:00 AM PST In Sushi Bar Express you have to start a career as a Sushi chef and absorb all of the wise teachings of your master. He'll teach you how to slice, dice, roll and hammer sushi and serve it to customers as a delicious restaurant quality dish. Your customers are ordering different types of sushi and you need to keep upgrading your equipment and recipes in order to make a healthy profit before the day is over. In the cartoon style of some of the most popular casual games out in the market today you strive to be a master yourself one day! |
Posted: 07 Mar 2012 02:53 AM PST Chester is a 2D platformer with over 10 unlockable and unique characters (ranging from spaceships, tanks, mimes, gentlemen, and more!) a light RPG element and leveling up system, loads of unlockables, around 50 levels, and 8 "styles" that allow the player to change the look of the game at will. These styles include sketchbook, 8-bit, LCD, blueprints, and many more and also each give a unique gameplay bonus to the player! The game also includes 4 difficulty levels so that almost anyone can beat the game or get a very challenging experience out of it. |
SurgeMail 60a4 - Easy to install and manage mail server.. (Shareware) Posted: 07 Mar 2012 03:18 AM PST SurgeMail Mail Server is a complete, advanced Mail Server, SurgeMail is secure, easy to install and manage. This email server is fast, reliable and feature rich, with integrated WebMail. Users can create and manage blogs. Advanced spam filtering, enhanced SPF stops most spam early. Supports all relevant RFC protocols POP3, SMTP, IMAP4, LDAP, HTTP, TLS/SSL. Highly scalable, 10 to unlimited users, unlimited domains. Version 60a4:
Mac OS X 10.4 or later Download Now This posting includes an audio/video/photo media file: Download Now |
A Better Finder Rename 9.02 - File, photo, and MP3 batch renamer.. (Shareware) Posted: 07 Mar 2012 02:55 AM PST A Better Finder Rename is the most complete renaming solution available on the market today. That's why, since 1996, tens of thousands of hobbyists, professionals and businesses depend on A Better Finder Rename to organize and maintain files. A Better Finder Rename's user interface supports complex renaming tasks without sacrificing ease and speed of use. Simply drag the files you want to rename straight from the Finder into the large preview table or the application icon.. or use our Finder context menu and hot key. The Instant Preview feature eliminates guesswork and costly errors and helps you find the right settings quickly and accurately by providing as-you-type feedback. A Better Finder Rename offers a complete set of renaming options that are organized into 15 categories covering all the text, character, position, conversion and truncation features that you would expect from a file renamer, but it does not stop there. Photographers use the advanced sequence number and date & time features to clean up their portfolios or prepare photos for delivery to their client. A Better Finder Rename knows how to extract EXIF shooting date and time information from digital camera images and exploit them in creating sequence numbers or adding time and date information to the file name. Support for all major RAW formats (including JPEG, CRW, CR2, THM, NEF, TIFF, RAJ, ORF , MRW, DNG, PEF, SRF, etc.) extends this to professional photographers. A Better Finder Rename also deals gracefully with multiple shots captured in the same second. Version 9 adds support for extracting camera, lens, photo and color meta-data tags and using them in the new tag rename feature. You can now also re-order sequence numbers, alphabetical sequences or roman numeral series directly through dragging and dropping items in the preview list. System administrators, web masters and other power users will appreciate the presence of advanced features, such as regular expression support, conversion to Windows NTFS/SMB compatible names, the ability to import file names from a database, a spreadsheet or any other source that can produce plain or tab-delimited text files. Last but not least, the ability to save a record of the current and new file names greatly facilitates tracking your files. Music lovers can use the built-in MP3/AAC support to exploit the id3 meta-data tags embedded in your most music files to create their own naming schemes for their music collection. Meta-data information from MP3, AAC, FLAC, OGG, APE, M4V and iTunes music store files are supported. The multi-step renaming feature allows multiple renaming steps to be combined to deal with complex renaming jobs in a single operation. Unlike other tools, A Better Finder Rename allows any number of renaming actions to be combined, re-ordered, copied and deleted.
Mac OS X 10.6 or later Download Now |
TerraRay 6.5.1 - Create realistic landscape images.. (Demo) Posted: 07 Mar 2012 02:53 AM PST TerraRay is an easy-to-use terrain rendering suite for your Mac. Create stunning artwork without learning a complicated and expensive application, TerraRay allows you to create realistic landscape images with just a few clicks while offering many advanced features for you to explore. What TerraRay offers:
Version 6.5.1:
Mac OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
Pokemon champion stripped of his title after alleged 'poo fight' in hotel Posted: 07 Mar 2012 02:41 AM PST |
Posted: 07 Mar 2012 12:00 AM PST It is known that the ATP-binding cassette transporter A1 (ABCA1) plays a major role in cholesterol homeostasis and high density lipoprotein (HDL) metabolism. Several laboratories have demonstrated that ABCA1 binding to lipid-poor apolipoprotein A-I (apoA-I) will mediate the assembly of nascent HDL and cellular cholesterol efflux, which suggests a possible receptor-ligand interaction between ABCA1 and apoA-I. In this study, a cell-based-ELISA-like high-throughput screening (HTS) method was developed to identify the synthetic and natural compounds that can regulate binding activity of ABCA1 to apoA-I. The cell-based-ELISA-like high-throughput screen was conducted in a 96-well format using Chinese hamster ovary (CHO) cells stably transfected with ABCA1 pIRE2-EGFP (Enhanced Green Fluorecence Protein) expression vector and the known ABCA1 inhibitor glibenclamide as the antagonist control. From 2,600 compounds, a xanthone compound (IMB 2026791) was selected using this HTS assay, and it was proved as an apoA-I binding agonist to ABCA1 by a flow cytometry assay and western blot analysis. The [3H] cholesterol efflux assay of IMB2026791 treated ABCA1-CHO cells and PMA induced THP-1 macrophages (human acute monocytic leukemia cell) further confirmed the compound as an accelerator of cholesterol efflux in a dose-dependent manner with an EC50 of 25.23 μM. |
Posted: 07 Mar 2012 12:00 AM PST The route selection and development of a convenient synthesis of 4-carboxy-4-anilidopiperidines is described. Previous routes were hampered by the low yield of the target esters as well as the inability to convert the esters to the required free acids. Considerations for large-scale production led to a modified synthesis that utilised a tert-butyl ester of 4-carboxy-4-anilidopiperidines which resulted in a dramatic increase in the overall yield of the target N-propionylated- 4-anilidopiperidine-4-carboxylic acids and their corresponding methyl esters. These compounds are now available for use as precursors and reference standards, of particular value for the production of 11C and 18F-labelled 4-carboxy-4-anilidopiperidine radiotracers. |
Marine Drugs, Vol. 10, Pages 604-616: Fucoxantin: A Treasure from the Sea Posted: 07 Mar 2012 12:00 AM PST The World Health Organization (WHO) estimates that 2.3 billion people will be overweight and 700 million obese in 2015. The reasons for this disastrous trend are attributed to the global tendency toward the reduced magnitude of exercise and physical activity and the increased dietary intake of fats, sugars and calories with reduced amount of vitamins and minerals. To prevent life-style-related diseases, like Metabolic Syndrome (MS), researchers' attention is increasingly focusing on some of the so called "functional foods" which may be useful for their prevention and treatment. One of these functional ingredients is fucoxanthin (FX), a characteristic carotenoid present in edible brown seaweeds, such as Undaria pinnatifida (Wakame), Hijikia fusiformis (Hijiki), Laminaria japonica (Ma-Kombu) and Sargassum fulvellum. The increasing popularity of this molecule is certainly due to its anti-obesity effect, primarily detected by murine studies. These works revealed FX mediated induction of uncoupling protein-1 (UCP-1) in abdominal white adipose tissue (WAT) mitochondria, leading to the oxidation of fatty acids and heat production in WAT. Beyond this important role, in recent studies FX has shown a great antioxidant activity, anti-cancer, anti-diabetic and anti-photoaging properties. The aim of this review is to highlight the main effects of FX on human health. |
Symmetry, Vol. 4, Pages 225-250: Classical Knot Theory Posted: 07 Mar 2012 12:00 AM PST This paper is a very brief introduction to knot theory. It describes knot coloring by quandles, the fundamental group of a knot complement, and handle-decompositions of knot complements. |
Posted: 07 Mar 2012 12:00 AM PST Accurate wind power forecasts highly contribute to the integration of wind power into power systems. The focus of the present study is on large-scale offshore wind farms and the complexity of generating accurate probabilistic forecasts of wind power fluctuations at time-scales of a few minutes. Such complexity is addressed from three perspectives: (i) the modeling of a nonlinear and non-stationary stochastic process; (ii) the practical implementation of the model we proposed; (iii) the gap between working on synthetic data and real world observations. At time-scales of a few minutes, offshore fluctuations are characterized by highly volatile dynamics which are difficult to capture and predict. Due to the lack of adequate on-site meteorological observations to relate these dynamics to meteorological phenomena, we propose a general model formulation based on a statistical approach and historical wind power measurements only. We introduce an advanced Markov Chain Monte Carlo (MCMC) estimation method to account for the different features observed in an empirical time series of wind power: autocorrelation, heteroscedasticity and regime-switching. The model we propose is an extension of Markov-Switching Autoregressive (MSAR) models with Generalized AutoRegressive Conditional Heteroscedastic (GARCH) errors in each regime to cope with the heteroscedasticity. Then, we analyze the predictive power of our model on a one-step ahead exercise of time series sampled over 10 min intervals. Its performances are compared to state-of-the-art models and highlight the interest of including a GARCH specification for density forecasts. |
Browser 1.1 - WebKit-based browser.. (Free) Posted: 07 Mar 2012 02:41 AM PST Editor's Note: As some of our users have pointed out, Browser features adult-oriented icons and search modes that parents and guardians may not find appropriate for younger users. The developer has accordingly added the option of a Parental Control mode, which can be chosen on first running this application. Browser is a Browser. A browser with WebKit inside - thus there is no need to tell you about the browsing experience. There's simply is no better way to surf the web. So - why another one? Because browsing should be about finding - not searching. Finding websites, content, bookmarks and pages stored for reading later. Tag it, baby! Tired of searching for bookmarks? Need your brain for more important tasks than remembering URLs? That's why Browser allows to tag bookmarks and directly open them by simply searching for such a tag. And because sometimes a tag isn't enough - Browser also allows to make use of comments. Drobox. Enabled All bookmarks, all pages stored for later reading are automatically available on all your Macs. Incl. all your tags and comments. History. Repeating. But wouldn't it be great to actually have the complete history on all Macs available as well? Guess what. 12345. Fail. And because we all use such risky passwords, Browser will store secure ones for you. And you only have to remember a single one. Lots more.
Version 1.1:
Download Now This posting includes an audio/video/photo media file: Download Now |
Entropy 1.4.1 - Versatile and easy to use archiver.. (Shareware) Posted: 07 Mar 2012 02:46 AM PST Entropy is a versatile and easy to use archiver capable of creating, modifying and extracting many archive formats.allows you create, modify and extract popular archive formats like zip, 7z and tar. A versatile tool, Entropy allows you to :
Version 1.4.1: Improvements
Mac OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
Posted: 07 Mar 2012 02:33 AM PST Mini Golf 3D is an extensive, feature-rich game with progressive play. The game involves putting a golf ball into 54 holes spread across 3 increasingly challenging levels of 18 holes each. Do this in the least possible strokes and you could be on your way to winning virtual medals and trophies! This highly customizable game lets you choose to play as 1 of 5 exciting characters, each having their own personality. The levels are designed to ensure maximum fun and replayability through multiple challenges consisting of moving & static obstacles and hazards, just like the real thing! Grab a putter and enjoy the coolest 3D golf experience this season! Features: - The most fun and addictive Mini-Golf game with 54 exciting pars & 4 unique game modes, spread across 3 beautiful environments. - Play 18 holes free & with 36 additional holes for purchase within the game. - Compete against yourself and other players on the global leaderboards. - Collect tons of achievements. - Show off your high scores and kick up a challenge on Facebook or Twitter. |
Omerta - City of Gangsters - Screenshots Posted: 07 Mar 2012 02:21 AM PST The player strategically manages his business and his minions in a real-time format, slowly but steadily increasing his influence over the city. The player sends his henchmen out on missions ranging from assassinating an informant, to raiding a warehouse, springing a friend from prison, robbing a bank, or attacking a rival gang's hideout. Nobody is above the law in Atlantic City, so it always helps to have a little cash handy to bribe a policeman or pay off a politician. The turn-based combat in Omerta - City of Gangsters focuses on the tactical command of "The Boss" and his henchmen. Cover and stealth are essential parts of any shootout in the game. Finding the best vantage point to gun down an enemy, while taking cover from a hailstorm of bullets, can be just as satisfying as sneaking quietly behind a foe and taking him down. - Historically accurate representation of Atlantic City and its landmarks - Strategic gameplay allows city overview, planning, expansion and gathering of intel - Turn-based tactical combat with a cover system and stealth action - 15 unique player controlled characters each with a unique personalities and backgrounds - An RPG system for development of player characters and managing their gear - Competitive and cooperative multiplayer mode with persistent multiplayer gang - 15+ hours of gameplay in a single play-through - 20 unique maps visualizing the various districts of Atlantic City |
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