Games |
- PlayStation Vita launch guide drops to 69p for the Easter Weekend on Apple Newsstand
- SteelWar Online - Screenshots
- Marvel Pinball - Screenshots
- Brave: The Video Game - Screenshots
- USB to Ethernet Connector 1.0 - Share remote USB devices over the internet.. (Shareware)
- IJMS, Vol. 13, Pages 4351-4366: Ultraviolet C Irradiation Induces Different Expression of Cyclooxygenase 2 in NIH 3T3 Cells and A431 Cells: The Roles of COX-2 Are Different in Various Cell Lines
- IJMS, Vol. 13, Pages 4340-4350: Synthesis of Zinc Oxide Nanoparticles and Their Effect on the Compressive Strength and Setting Time of Self-Compacted Concrete Paste as Cementitious Composites
- Lep's World - Screenshots
- Fibble - Screenshots
- TrialX2 Winter Free - Screenshots
- Cordy Sky - Screenshots
- Tower 1.4.5 - Comprehensive frontend for Git version control software.. (Demo)
- Pro Maintenance Tools 2.0.7 - Keep your video production apps running at optimal performance.. (Demo)
- Administrative Sciences, Vol. 2, Pages 135-147: Urban Governance of Disease
- Viruses, Vol. 4, Pages 447-470: Structural Basis for Differential Neutralization of Ebolaviruses
- Marine Drugs, Vol. 10, Pages 849-880: Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems
- Molecules, Vol. 17, Pages 4225-4235: HCN Channels and Heart Rate
- Molecules, Vol. 17, Pages 4219-4224: A Novel Antioxidant Isobenzofuranone Derivative from Fungus Cephalosporium sp.AL031
- Molecules, Vol. 17, Pages 4209-4218: Synthesis and NMR Spectral Studies of the 7-C60-Adduct of N,N-(Tetrachlorophthaloyl) Dehydroabietylamine
- Sound Byte Radio Episode 2: Hitman: Blood Money, FF XIII, Mass Effect
| PlayStation Vita launch guide drops to 69p for the Easter Weekend on Apple Newsstand Posted: 05 Apr 2012 03:23 AM PDT
|
| Posted: 05 Apr 2012 04:17 AM PDT |
| Posted: 05 Apr 2012 04:02 AM PDT Marvel Pinball is the first expansion for Pinball FX 2 on Xbox LIVE Arcade, which released to rave reviews on October 27th, 2010, as part of Game Feast presented by Microsoft Game Studios, and it will be an entirely new game on PlayStation Network. Marvel Pinball consists of four Super Hero-themed pinball tables integrating artwork, themes and music inspired by the Marvel Universe. |
| Brave: The Video Game - Screenshots Posted: 05 Apr 2012 04:29 AM PDT |
| USB to Ethernet Connector 1.0 - Share remote USB devices over the internet.. (Shareware) Posted: 05 Apr 2012 03:12 AM PDT  USB to Ethernet Connector lets your computer work with remote USB devices over Internet/LAN/WAN as if those devices were connected directly to this computer. You can share a USB device with remote computers no matter how far they are and let people all over the world use them easily. By intercepting USB port activity of a shared USB device and redirecting it via TCP/IP network USB to Ethernet Connector lets you access your printer, scanner, web-cam, USB dongle or any other supported USB device from your home computer or office laptop anywhere any time! Just plug the device in and it will automatically appear on the remote side of the connection. Version 1.0: initial release. Mac OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 05 Apr 2012 12:00 AM PDT Ultraviolet C (UVC) is a DNA damage inducer, and 20 J/m2 of UVC irradiation caused cell growth inhibition and induced cell death after exposure for 24–36 h. The growth of NIH 3T3 cells was significantly suppressed at 24 h after UVC irradiation whereas the proliferation of A431 cells was inhibited until 36 h after UVC irradiation. UVC irradiation increased COX-2 expression and such up-regulation reached a maximum during 3–6 h in NIH 3T3 cells. In contrast, UVC-induced COX-2 reached a maximum after 24–36 h in A431 cells. Measuring prostaglandin E2 (PGE2) level showed a biphasic profile that PGE2 release was rapidly elevated in 1–12 h after UVC irradiation and increased again at 24 h in both cell lines. Treatment with the selective COX-2 inhibitor, SC-791, during maximum expression of COX-2 induction, attenuated the UVC induced-growth inhibition in NIH 3T3 cells. In contrast, SC-791 treatment after UVC irradiation enhanced death of A431 cells. These data showed that the patterns of UVC-induced PGE2 secretion from NIH 3T3 cells and A431 cells were similar despite the differential profile in UVC-induced COX-2 up-regulation. Besides, COX-2 might play different roles in cellular response to UVC irradiation in various cell lines. |
| Posted: 05 Apr 2012 12:00 AM PDT In the present study, the mechanical properties of self-compacting concrete were investigated after the addition of different amounts of ZnO nanoparticles. The zinc oxide nanoparticles, with an average particle size of about 30 nm, were synthesized and their properties studied with the help of a scanning electron microscope (SEM) and X-ray diffraction. The prepared nanoparticles were partially added to self-compacting concrete at different concentrations (0.05, 0.1, 0.2, 0.5 and 1.0%), and the mechanical (flexural and split tensile) strength of the specimens measured after 7, 14, 21 and 28 days, respectively. The present results have shown that the ZnO nanoparticles were able to improve the flexural strength of self-compacting concrete. The increased ZnO content of more than 0.2% could increase the flexural strength, and the maximum flexural and split tensile strength was observed after the addition of 0.5% nanoparticles. Finally, ZnO nanoparticles could improve the pore structure of the self-compacted concrete and shift the distributed pores to harmless and less-harmful pores, while increasing mechanical strength. |
| Posted: 05 Apr 2012 03:54 AM PDT Features: - 4 incredible levels - wonderful graphics - 5 different themes - 8 challenging enemies - Game Center with some tricky achievements - Game Center with five awesome leaderboards - multiplayer - Retina support |
| Posted: 05 Apr 2012 03:34 AM PDT HELP FIBBLE TO FIND HIS FRIENDS In the dramatic crash, Fibble becomes separated from his crew as they're scattered all over the mysterious house. Combine the unique skills of Fibble's friends and discover all sorts of new possibilities: Overcome obstacles with some help from Byte, scale new heights with Ragno and inject some speed into proceedings with a boost from Vroom or Docto. INTUITIVE TAP CONTROLS FOR FAST-PACED FUN Use intuitive taps of the touch screen to flick, roll and control Fibble as he embarks on an adventure to reassemble his crew and blast back into space. VIBRANT, CRYTEK CONSOLE QUALITY 3D GRAPHICS Experience high-definition gaming like never before supported by top-notch features completely new to the mobile experience powered by CryENGINE. HIGH QUALITY REAL TIME 3D CINEMATICS Learn more about Fibble's dramatic adventure with his adorably cute crew in high-quality realtime 3D cinematics in 'Fibble – Flick 'n' Roll'. CHALLENGING PHYSICS-BASED GAMEPLAY AND HOURS OF REPLAY VALUE. Enjoy a groundbreaking gameplay experience that is highly addictive and guarantees many hours of sheer fun. BECOME THE ULTIMATE MASTER OF THE GAME Along the way there are achievements to bag, objectives to complete and online scoreboards to climb—all of which will keep you coming back for more! |
| TrialX2 Winter Free - Screenshots Posted: 05 Apr 2012 03:58 AM PDT Game Features: - Much anticipated sequel to the blockbuster hit Trial Xtreme 2- downloaded 10 million times and counting! - Available for Apple iPhone, iPad and iPod Touch - Amazing new levels in a cold snowy environment - Negotiate hundreds of obstacles including ramps, jumbo tires, rocks, planks and more - Super detailed new Unity-powered graphics engine brings your rider and the game world to life - Intuitive tilt control system using the phone's accelerometer. Use precision control like never before - Ultra-realistic rider and bike physics built on the NVIDIA® PhysX® engine lets you feel it all as you flip, jump, bump and crash your way to victory - Max out your score and play the world through Gamecenter highscores. - Improve your score by collecting starts while riding through obstacles. |
| Posted: 05 Apr 2012 03:46 AM PDT PARENTS! It's possible to spend real money inside this game. You can disable In-App Purchase in your device's Settings menu. SPEND GEARS ON AMAZING UPGRADES. There are Power-Ups, Costumes, and Colors. You can earn Gears in the game OR buy them if you're in a hurry! COOL ACHIEVEMENTS. Earn badges for style. Do you have what it takes? NEVERENDING FUN. Finish the story, then see how high you can go. GAME CENTER ENABLED. See how you compare to your friends, on the leaderboard. TRY THE ORIGINAL "CORDY" GAME, TOO! One of the Top 10 best games of 2011 -The New York Times. #1 app in the United States, Canada, China, Germany, France, Spain, and many more! Featured "New & Noteworthy", "Staff Favorite" and "App of the Week" by Apple in numerous countries. WANT MORE GAMES LIKE THIS? Play SLEEPY JACK! Top 10 Best of E3: "Adorable Psychonauts-esque presentation and solid gameplay...that is also tight and arcadey" -Pocket Gamer BEST APP OF THE WEEK: "It's the sort of happiness-inducing experience that you want to share with everyone." -Kotaku 8 LANGUAGES. Supports Spanish, French, German, Italian, Russian, Korean, Chinese, and Japanese. Pick one of these in your device's Settings menu. |
| Tower 1.4.5 - Comprehensive frontend for Git version control software.. (Demo) Posted: 05 Apr 2012 02:41 AM PDT  Tower is a powerful Git Client for Mac OS X that makes using Git easy and more efficient. Users benefit from its elegant and comprehensive interface and a feature set that lets them enjoy the full power of Git. You can download a free 30-day trial with all features. Students receive a 50% discount. Features include:
Version 1.4.5:
Mac OS X 10.5 or later Download Now |
| Posted: 05 Apr 2012 02:51 AM PDT  Pro Maintenance Tools is a utility pack designed to keep your Final Cut Studio, Final Cut Pro X, Avid Media Composer and Adobe Premiere Pro machine running at optimal performance and help resolve problems when they arise. Major problems always seem to occur right on a deadline - Pro Maintenance Tools is designed to quickly diagnose and fix common issues, ensuring you meet your deadline. With the Task Scheduler utility, you can even schedule maintenance tasks in the background and not have to worry about them. Pro Maintenance Tools includes:
Version 2.0.7:
Download Now |
| Administrative Sciences, Vol. 2, Pages 135-147: Urban Governance of Disease Posted: 05 Apr 2012 12:00 AM PDT Rapid population growth, urbanization, and the growing challenges faced by the urban poor require redefining the paradigm for public health interventions in the 21st century, creating new approaches that take urban determinants of health into consideration. The widening disparity between the urban poor and the urban rich further exacerbates health inequities. Existing tools for global governance of urban health risks fall short, particularly in the lack of formal mechanisms to strengthen collaboration and communication among national and municipal agencies and between their local and international non-governmental partners. There is also a clear disconnect between governance strategies crafted at the international level and implementation on the ground. The challenge is to find common ground for global goods and municipal needs, and to craft innovative and dynamic policy solutions that can benefit some of the poorest citizens of the global urban network. |
| Viruses, Vol. 4, Pages 447-470: Structural Basis for Differential Neutralization of Ebolaviruses Posted: 05 Apr 2012 12:00 AM PDT There are five antigenically distinct ebolaviruses that cause hemorrhagic fever in humans or non-human primates (Ebola virus, Sudan virus, Reston virus, Taï Forest virus, and Bundibugyo virus). The small handful of antibodies known to neutralize the ebolaviruses bind to the surface glycoprotein termed GP1,2. Curiously, some antibodies against them are known to neutralize in vitro but not protect in vivo, whereas other antibodies are known to protect animal models in vivo, but not neutralize in vitro. A detailed understanding of what constitutes a neutralizing and/or protective antibody response is critical for development of novel therapeutic strategies. Here, we show that paradoxically, a lower affinity antibody with restricted access to its epitope confers better neutralization than a higher affinity antibody against a similar epitope, suggesting that either subtle differences in epitope, or different characteristics of the GP1,2 molecules themselves, confer differential neutralization susceptibility. Here, we also report the crystal structure of trimeric, prefusion GP1,2 from the original 1976 Boniface variant of Sudan virus complexed with 16F6, the first antibody known to neutralize Sudan virus, and compare the structure to that of Sudan virus, variant Gulu. We discuss new structural details of the GP1-GP2 clamp, thermal motion of various regions in GP1,2 across the two viruses visualized, details of differential interaction of the crystallized neutralizing antibodies, and their relevance for virus neutralization. |
| Posted: 05 Apr 2012 12:00 AM PDT Marine systems are very diverse and recognized as being sources of a wide range of biomolecules. This review provides an overview of metabolite profiling based on mass spectrometry (MS) approaches in marine organisms and their environments, focusing on recent advances in the field. We also point out some of the technical challenges that need to be overcome in order to increase applications of metabolomics in marine systems, including extraction of chemical compounds from different matrices and data management. Metabolites being important links between genotype and phenotype, we describe added value provided by integration of data from metabolite profiling with other layers of omics, as well as their importance for the development of systems biology approaches in marine systems to study several biological processes, and to analyze interactions between organisms within communities. The growing importance of MS-based metabolomics in chemical ecology studies in marine ecosystems is also illustrated. |
| Molecules, Vol. 17, Pages 4225-4235: HCN Channels and Heart Rate Posted: 05 Apr 2012 12:00 AM PDT Hyperpolarization and Cyclic Nucleotide (HCN) -gated channels represent the molecular correlates of the "funny" pacemaker current (If), a current activated by hyperpolarization and considered able to influence the sinus node function in generating cardiac impulses. HCN channels are a family of six transmembrane domain, single pore-loop, hyperpolarization activated, non-selective cation channels. This channel family comprises four members: HCN1-4, but there is a general agreement to consider HCN4 as the main isoform able to control heart rate. This review aims to summarize advanced insights into the structure, function and cellular regulation of HCN channels in order to better understand the role of such channels in regulating heart rate and heart function in normal and pathological conditions. Therefore, we evaluated the possible therapeutic application of the selective HCN channels blockers in heart rate control. |
| Posted: 05 Apr 2012 12:00 AM PDT Bioassay-guided fractionation of metabolites from the fungus Cephalosporium sp.AL031 isolated from Sinarundinaria nitida led to the discovery of a new isobenzofuranone derivative, 4,6-dihydroxy-5-methoxy-7-methylphthalide (1), together with three known compounds: 4,5,6-trihydroxy-7-methyl-1,3-dihydroisobenzofuran (2), 4,6-dihydroxy-5-methoxy-7-methyl-1,3-dihydroisobenzofuran (3) and 4,5,6-trihydroxy-7-methylphthalide (4). The structure of the new compound 1 was determined based on MS, 1D and 2D NMR spectral data. Compounds 1–4 showed potent antioxidant activity with EC50 values of 10, 7, 22 and 5 μM by 1,1-diphenyl-2-picryhydrazyl (DPPH) radical-scavenging assay. |
| Posted: 05 Apr 2012 12:00 AM PDT The 7-C60-adduct of N,N-(tetrachlorophthaloyl)dehydroabietylamine was synthesized for the first time and characterized by IR, UV-vis, mass and NMR spectral studies. The 1H-NMR and 13C-NMR resonance signals of the new compound are unambiguously assigned by using homo- and heteronuclear 2D NMR spectroscopic techniques such as COSY, ROESY, HSQC and HMBC. The C1 symmetric structure with 6,6-junction of compound was determined. |
| Sound Byte Radio Episode 2: Hitman: Blood Money, FF XIII, Mass Effect Posted: 04 Apr 2012 09:45 PM PDT On GameSpot's next music podcast episode, we check out the music of Hitman, FF XIII, and even a little bit of a Mass Effect tribute.
Get the full article at GameSpot "Sound Byte Radio Episode 2: Hitman: Blood Money, FF XIII, Mass Effect" was posted by Jonathan Toyad on Wed, 04 Apr 2012 21:45:59 -0700 |
| You are subscribed to email updates from Games To stop receiving these emails, you may unsubscribe now. | Email delivery powered by Google |
| Google Inc., 20 West Kinzie, Chicago IL USA 60610 | |
Комментариев нет:
Отправить комментарий