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- Toxins, Vol. 4, Pages 281-295: Influence of Mycotoxins and a Mycotoxin Adsorbing Agent on the Oral Bioavailability of Commonly Used Antibiotics in Pigs
- IJMS, Vol. 13, Pages 5254-5277: Phage Displayed Peptides/Antibodies Recognizing Growth Factors and Their Tyrosine Kinase Receptors as Tools for Anti-Cancer Therapeutics
- Diversity, Vol. 4, Pages 196-223: Diversity of Mat-Forming Fungi in Relation to Soil Properties, Disturbance, and Forest Ecotype at Crater Lake National Park, Oregon, USA
- Seeing Red - Bloodforge Gameplay Video
- Raging Crom - Bloodforge Gameplay Video
- Laserin' Cyclops - Bloodforge Gameplay Video
- Zweifish 1.0 - Encryption application.. (Commercial)
- Windownaut 1.0 - Lightweight window manager.. (Shareware)
- MoneyMoney 1.3.0 - German banking application.. (Commercial)
- Vitamin-R 1.79 - Personal productivity tool.. (Shareware)
- Crystals, Vol. 2, Pages 327-337: Halogen Bonding Interactions in DDQ Charge Transfer Salts with Iodinated TTFs
- Energies, Vol. 5, Pages 1245-1270: A Low-Carbon Dispatch Model in a Wind Power Integrated System Considering Wind Speed Forecasting and Energy-Environmental Efficiency
- Robotics, Vol. 1, Pages 1-2: Robotics — Inspired from Nature
- Religions, Vol. 3, Pages 339-343: False Gods and the Two Intelligent Questions of Metapsychiatry
- Cisco Jabber Video for TelePresence 4.4.3.14479 - Cloud-based collaborative workspace. . (Commercial)
- Roccat Browser 2.4 - Fast Web browser with a variety of features.. (Free)
- Superbrothers: Sword & Sworcery EP Review
- Gameplay Demo - Sniper
- Toddler's Seek & Find: My Little Town. An interactive activity book. Screens
- Toddler's Seek & Find - My Animals. An interactive activity book showing zoo, farm and forest.. Screens
Posted: 24 Apr 2012 12:00 AM PDT It is recognized that mycotoxins can cause a variety of adverse health effects in animals, including altered gastrointestinal barrier function. It is the aim of the present study to determine whether mycotoxin-contaminated diets can alter the oral bioavailability of the antibiotics doxycycline and paromomycin in pigs, and whether a mycotoxin adsorbing agent included into diets interacts with those antibiotics. Experiments were conducted with pigs utilizing diets that contained blank feed, mycotoxin-contaminated feed (T-2 toxin or deoxynivalenol), mycotoxin-contaminated feed supplemented with a glucomannan mycotoxin binder, or blank feed supplemented with mycotoxin binder. Diets with T-2 toxin and binder or deoxynivalenol and binder induced increased plasma concentrations of doxycycline administered as single bolus in pigs compared to diets containing blank feed. These results suggest that complex interactions may occur between mycotoxins, mycotoxin binders, and antibiotics which could alter antibiotic bioavailability. This could have consequences for animal toxicity, withdrawal time for oral antibiotics, or public health. |
Posted: 24 Apr 2012 12:00 AM PDT The basic idea of displaying peptides on a phage, introduced by George P. Smith in 1985, was greatly developed and improved by McCafferty and colleagues at the MRC Laboratory of Molecular Biology and, later, by Barbas and colleagues at the Scripps Research Institute. Their approach was dedicated to building a system for the production of antibodies, similar to a naïve B cell repertoire, in order to by-pass the standard hybridoma technology that requires animal immunization. Both groups merged the phage display technology with an antibody library to obtain a huge number of phage variants, each of them carrying a specific antibody ready to bind its target molecule, allowing, later on, rare phage (one in a million) to be isolated by affinity chromatography. Here, we will briefly review the basis of the technology and the therapeutic application of phage-derived bioactive molecules when addressed against key players in tumor development and progression: growth factors and their tyrosine kinase receptors. |
Posted: 24 Apr 2012 12:00 AM PDT In forest ecosystems, fungal mats are functionally important in nutrient and water uptake in litter and wood decomposition processes, in carbon resource allocation, soil weathering and in cycling of soil resources. Fungal mats can occur abundantly in forests and are widely distributed globally. We sampled ponderosa pine/white fir and mountain hemlock/noble fir communities at Crater Lake National Park for mat-forming soil fungi. Fungus collections were identified by DNA sequencing. Thirty-eight mat-forming genotypes were identified; members of the five most common genera (Gautieria, Lepiota, Piloderma, Ramaria, and Rhizopogon) comprised 67% of all collections. The mycorrhizal genera Alpova and Lactarius are newly identified as ectomycorrhizal mat-forming taxa, as are the saprotrophic genera Flavoscypha, Gastropila, Lepiota and Xenasmatella. Twelve typical mat forms are illustrated, representing both ectomycorrhizal and saprotrophic fungi that were found. Abundance of fungal mats was correlated with higher soil carbon to nitrogen ratios, fine woody debris and needle litter mass in both forest ecotypes. Definitions of fungal mats are discussed, along with some of the challenges in defining what comprises a fungal "mat". |
Seeing Red - Bloodforge Gameplay Video Posted: 23 Apr 2012 10:17 PM PDT Crom keeps the blood flowing in this early part of the game
Read and Post Comments | Get the full article at GameSpot "Seeing Red - Bloodforge Gameplay Video" was posted by edmondt on Mon, 23 Apr 2012 22:17:06 -0700 |
Raging Crom - Bloodforge Gameplay Video Posted: 23 Apr 2012 09:42 PM PDT Crom goes into berserker mode; not really good news for his enemies.
Read and Post Comments | Get the full article at GameSpot "Raging Crom - Bloodforge Gameplay Video" was posted by edmondt on Mon, 23 Apr 2012 21:42:59 -0700 |
Laserin' Cyclops - Bloodforge Gameplay Video Posted: 23 Apr 2012 09:41 PM PDT Watch as Crom beats off a horde of barbarians while a big giant overseas the action.
Read and Post Comments | Get the full article at GameSpot "Laserin' Cyclops - Bloodforge Gameplay Video" was posted by edmondt on Mon, 23 Apr 2012 21:41:54 -0700 |
Zweifish 1.0 - Encryption application.. (Commercial) Posted: 24 Apr 2012 02:40 AM PDT Zweifish is a tiny file encryption application using 256-bit Twofish encryption in CBC mode. Twofish is one of a few ciphers included in the OpenPGP standard.
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Windownaut 1.0 - Lightweight window manager.. (Shareware) Posted: 24 Apr 2012 02:46 AM PDT Windownaut is a lightweight and robust window resizer, mover and more that aims to have a very small footprint. It allows you to easily resize, move and add a variety of new control options to almost all app windows. Features
Version 1.0:
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MoneyMoney 1.3.0 - German banking application.. (Commercial) Posted: 24 Apr 2012 02:58 AM PDT MoneyMoney is the elegant way to keep track of your German bank accounts and to do bank transfers within Germany. Interactive account statements and precise infographics show all your finances at a glance. IMPORTANT: Currently only GERMAN BANK ACCOUNTS are fully supported (requires HBCI+/FinTS with PIN/TAN). PayPal balance and transactions import DOES WORK internationally. Because the user interface is in English, MoneyMoney is ideal in case you have a German bank account and you're not comfortable with the German language. MoneyMoney skips the cumbersome log-in to bank websites. Using HBCI+/FinTS and PIN/TAN technology, MoneyMoney supports most banks in Germany that do not require a chip card for online banking. With our new Web Banking engine, MoneyMoney can be extended with international financial services through Lua scripts. Please see www.moneymoney-app.com/api/webbanking for details. BANK TRANSFERS, SCHEDULED TRANSFERS, AND STANDING ORDERS The sleek payment window fits next to your mail app, your browser, or a PDF invoice. With our smart paste feature, you can turn an unstructured text block of payment info into a sendable bank transfer in one go. STAY UP TO DATE How much money do I spend per quarter? How much money have I accumulated over the last year? How much do I draw out at ATMs? The infographics in MoneyMoney show your account details better than any simple list. ROBUST SECURITY All information is transferred in a tap-proof connection between your Mac and the bank. MoneyMoney saves all your transactions and account credentials in a reliable database. You can optionally protect the database with a personal password. More details at www.moneymoney-app.com/security FIND INSTANTLY MoneyMoney allows you to filter and search all your transactions. Enter a search term, change the time period, or filter by transaction type. It will take only seconds to find things that you would still not have found after minutes of using your web browser. SUPPORTED BANKS: MoneyMoney supports many German banks, but ONLY GERMAN BANK ACCOUNTS ARE FULLY SUPPORTED! If your bank's data centre supports HBCI+ 2.2 with PIN/TAN 1.01 extension or FinTS 3.0 with PIN/TAN, MoneyMoney should work. Please visit http://moneymoney-app.com to find out whether your bank is supported. Thank you! More Banking
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Vitamin-R 1.79 - Personal productivity tool.. (Shareware) Posted: 24 Apr 2012 02:33 AM PDT Vitamin-R creates the optimal conditions for your brain to work at its best by structuring your work into short bursts of distraction-free, highly focused activity alternating with opportunities for renewal, reflection and intuition. The built-in task logging and statistics features create a positive momentum towards productivity by providing visible feedback on your progress and achievements. Time Slice Your Work Vitamin-R breaks down large, vaguely defined tasks into a series of short "time slices" of between 10 and 30 minutes, each with specific, easily reachable and actionable objectives. During these time slices it keeps you focused on accomplishing only this one objective and provides you with mechanisms for dealing with interruptions, poor concentration, etc. Get Started Vitamin-R concentrates on getting you started allowing you to break through the resistance of procrastination and create a positive feedback loop of small achievements that get you closer to your ultimate aims. You will experience less stress caused by looming deadlines and a lack of clear direction, thus enabling you to enjoy guilt-free breaks that allow your intuition and creativity to emerge. Find Your Rhythm Each one of us is different. Finding out what works best for you is the key to true productivity. Vitamin-R helps you by giving you the tools to gain more awareness of how you spend your time, what works for you and what does not. Armed with this new knowledge, you can eliminate unproductive work patterns and discover the work rhythm that suits you best. Get It Out of Your Head Quickly Did you know that your short term memory can only hold 4-6 "chunks" of information? The slightest interruption and it's all gone and you have to start from scratch. That's why Vitamin-R provides you with the "Now & Later Board", complete with FastType magic, to give you a place to quickly dump all those things that go through your head and allow you to quickly return to your task. Make It Your Own Vitamin-R plugs into your life rather than trying to take it over. You can use it occasionally to overcome procrastination or mental blocks or re-organize your entire working life around the concepts that it embodies. It complements rather than replaces traditional to-do list managers, such as Things or OmniFocus for which direct integrations exist. Now With Cloud Synching! If you routinely work on multiple Macs, you willlove Vitamin-R's new ability to effortlessly synch your time slice log across the cloud using the free Dropbox service. Setup is as easy as ticking a checkbox. Recapture the lost of art of joyful concentration. Overcome procrastination. Rediscover the motivation within yourself. Version 1.79:
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Posted: 24 Apr 2012 12:00 AM PDT Oxidation of 3,4-ethylenedithio-3'-iodo-tetrathiafulvalene (EDT-TTF-I) and 3,4-ethylenedithio-3',4'-diiodo-tetrathiafulvalene (EDT-TTF-I2) with DDQ afforded two different salts formulated as (EDT-TTF-I)(DDQ) and (EDT-TTF-I2)2(DDQ)·(CH3CN), both characterized with a full charge transfer to the DDQ acceptor moiety and by short and linear halogen bonding interactions between the iodine atom as halogen bond donor, and the carbonyl oxygen or the nitrile nitrogen atoms of reduced DDQ. |
Posted: 24 Apr 2012 12:00 AM PDT This paper introduces the "Energy-Environmental Efficiency" concept of building a low-carbon dispatch model of wind-incorporated power systems from the perspective of environmental protection and low-carbon dispatch promotion based on the existing economic environmental dispatch. A rolling auto-regressive and moving-average model is adopted to forecast wind speeds for the next 24 h and reduce the disadvantages brought about to the power system dispatch by wind speed fluctuations. A fuzzy satisfaction-maximizing approach is employed to convert the multi-objective decision-making problem in the low-carbon dispatch model into a single nonlinear one. Particle swarm optimization with a simulated annealing algorithm hybrid is used for better solutions. Simulation results show that the energy-environmental efficiency concept benefits the optimization of the proposed power system dispatch, and the proposed low-carbon dispatch model is reasonable and practical. |
Robotics, Vol. 1, Pages 1-2: Robotics — Inspired from Nature Posted: 24 Apr 2012 12:00 AM PDT It is my great pleasure to welcome you to a new open access journal, Robotics, which is dedicated to both the foundations of artificial intelligence, bio-mechanics, mechatronics and control theories, and the real-world applications of robotic perception, cognition and actions. This includes the innovative scientific trends, and discovery resulting from solving new challenges in the field of robotics. Its open access and rapid dissemination are the unique features separating this journal from all existing journals dedicated to robotics. [...] |
Religions, Vol. 3, Pages 339-343: False Gods and the Two Intelligent Questions of Metapsychiatry Posted: 24 Apr 2012 12:00 AM PDT This paper explains how the spiritual teaching known as Metapsychiatry, developed by psychiatrist Thomas Hora, employs two questions as its focal educational method. Those questions facilitate phenomenological discernment of the source (i.e. the meaning) of our problems in living and help students and patients to understand the real nature of God. Perceiving our existentially invalid attachments and the inevitable suffering they produce encourages us to seek inspiration from God. |
Posted: 24 Apr 2012 02:12 AM PDT Cisco Jabber Video for TelePresence (Jabber Video) is an application that extends the reach of telepresence. Jabber Video works with a compatible PC or Mac and a webcam or Cisco TelePresence PrecisionHD camera to provide high-definition video communications to more people, on more devices, from more places. Jabber Video can connect to telepresence systems, resulting in a wider community of colleagues, partners, and business customers. Version 4.4.3.13379: The following issues were found in previous releases and were resolved in 4.4:
Open issues:
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Roccat Browser 2.4 - Fast Web browser with a variety of features.. (Free) Posted: 24 Apr 2012 02:29 AM PDT Roccat Browser is an amazing browser from the fludium family. Roccat Browser is an amazingly fast Web browser, which has some great features such as:
Version 2.4:
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Superbrothers: Sword & Sworcery EP Review Posted: 23 Apr 2012 07:15 PM PDT Superbrothers: Sword & Sworcery EP is a beautiful and enthralling adventure that feels both archetypal and unique.
Score: 9.0 / superb Get the full article at GameSpot "Superbrothers: Sword & Sworcery EP Review" was posted by Carolyn Petit on Mon, 23 Apr 2012 19:15:48 -0700 |
Posted: 23 Apr 2012 05:45 PM PDT Hope you can duck fast, because we've got Sniper: Ghost Warrior 2 headed your way!
Read and Post Comments | Get the full article at GameSpot "Gameplay Demo - Sniper" was posted by Jan on Mon, 23 Apr 2012 17:45:31 -0700 |
Toddler's Seek & Find: My Little Town. An interactive activity book. Screens Posted: 23 Apr 2012 05:04 PM PDT 5 new shots posted.
Get the full article at GameSpot "Toddler's Seek & Find: My Little Town. An interactive activity book. Screens" was posted on Mon, 23 Apr 2012 17:04:09 -0700 |
Posted: 23 Apr 2012 05:04 PM PDT 5 new shots posted.
Get the full article at GameSpot "Toddler's Seek & Find - My Animals. An interactive activity book showing zoo, farm and forest.. Screens" was posted on Mon, 23 Apr 2012 17:04:05 -0700 |
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