вторник, 24 апреля 2012 г.

Games

Games


Toxins, Vol. 4, Pages 281-295: Influence of Mycotoxins and a Mycotoxin Adsorbing Agent on the Oral Bioavailability of Commonly Used Antibiotics in Pigs

Posted: 24 Apr 2012 12:00 AM PDT

It is recognized that mycotoxins can cause a variety of adverse health effects in animals, including altered gastrointestinal barrier function. It is the aim of the present study to determine whether mycotoxin-contaminated diets can alter the oral bioavailability of the antibiotics doxycycline and paromomycin in pigs, and whether a mycotoxin adsorbing agent included into diets interacts with those antibiotics. Experiments were conducted with pigs utilizing diets that contained blank feed, mycotoxin-contaminated feed (T-2 toxin or deoxynivalenol), mycotoxin-contaminated feed supplemented with a glucomannan mycotoxin binder, or blank feed supplemented with mycotoxin binder. Diets with T-2 toxin and binder or deoxynivalenol and binder induced increased plasma concentrations of doxycycline administered as single bolus in pigs compared to diets containing blank feed. These results suggest that complex interactions may occur between mycotoxins, mycotoxin binders, and antibiotics which could alter antibiotic bioavailability. This could have consequences for animal toxicity, withdrawal time for oral antibiotics, or public health.

IJMS, Vol. 13, Pages 5254-5277: Phage Displayed Peptides/Antibodies Recognizing Growth Factors and Their Tyrosine Kinase Receptors as Tools for Anti-Cancer Therapeutics

Posted: 24 Apr 2012 12:00 AM PDT

The basic idea of displaying peptides on a phage, introduced by George P. Smith in 1985, was greatly developed and improved by McCafferty and colleagues at the MRC Laboratory of Molecular Biology and, later, by Barbas and colleagues at the Scripps Research Institute. Their approach was dedicated to building a system for the production of antibodies, similar to a naïve B cell repertoire, in order to by-pass the standard hybridoma technology that requires animal immunization. Both groups merged the phage display technology with an antibody library to obtain a huge number of phage variants, each of them carrying a specific antibody ready to bind its target molecule, allowing, later on, rare phage (one in a million) to be isolated by affinity chromatography. Here, we will briefly review the basis of the technology and the therapeutic application of phage-derived bioactive molecules when addressed against key players in tumor development and progression: growth factors and their tyrosine kinase receptors.

Diversity, Vol. 4, Pages 196-223: Diversity of Mat-Forming Fungi in Relation to Soil Properties, Disturbance, and Forest Ecotype at Crater Lake National Park, Oregon, USA

Posted: 24 Apr 2012 12:00 AM PDT

In forest ecosystems, fungal mats are functionally important in nutrient and water uptake in litter and wood decomposition processes, in carbon resource allocation, soil weathering and in cycling of soil resources. Fungal mats can occur abundantly in forests and are widely distributed globally. We sampled ponderosa pine/white fir and mountain hemlock/noble fir communities at Crater Lake National Park for mat-forming soil fungi. Fungus collections were identified by DNA sequencing. Thirty-eight mat-forming genotypes were identified; members of the five most common genera (Gautieria, Lepiota, Piloderma, Ramaria, and Rhizopogon) comprised 67% of all collections. The mycorrhizal genera Alpova and Lactarius are newly identified as ectomycorrhizal mat-forming taxa, as are the saprotrophic genera Flavoscypha, Gastropila, Lepiota and Xenasmatella. Twelve typical mat forms are illustrated, representing both ectomycorrhizal and saprotrophic fungi that were found. Abundance of fungal mats was correlated with higher soil carbon to nitrogen ratios, fine woody debris and needle litter mass in both forest ecotypes. Definitions of fungal mats are discussed, along with some of the challenges in defining what comprises a fungal "mat".

Seeing Red - Bloodforge Gameplay Video

Posted: 23 Apr 2012 10:17 PM PDT

Crom keeps the blood flowing in this early part of the game

 

Read and Post Comments | Get the full article at GameSpot


"Seeing Red - Bloodforge Gameplay Video" was posted by edmondt on Mon, 23 Apr 2012 22:17:06 -0700

Raging Crom - Bloodforge Gameplay Video

Posted: 23 Apr 2012 09:42 PM PDT

Crom goes into berserker mode; not really good news for his enemies.

 

Read and Post Comments | Get the full article at GameSpot


"Raging Crom - Bloodforge Gameplay Video" was posted by edmondt on Mon, 23 Apr 2012 21:42:59 -0700

Laserin' Cyclops - Bloodforge Gameplay Video

Posted: 23 Apr 2012 09:41 PM PDT

Watch as Crom beats off a horde of barbarians while a big giant overseas the action.

 

Read and Post Comments | Get the full article at GameSpot


"Laserin' Cyclops - Bloodforge Gameplay Video" was posted by edmondt on Mon, 23 Apr 2012 21:41:54 -0700

Zweifish 1.0 - Encryption application.. (Commercial)

Posted: 24 Apr 2012 02:40 AM PDT



Zweifish is a tiny file encryption application using 256-bit Twofish encryption in CBC mode. Twofish is one of a few ciphers included in the OpenPGP standard.

  • Mac OS X 10.7 or later


Download Now

Windownaut 1.0 - Lightweight window manager.. (Shareware)

Posted: 24 Apr 2012 02:46 AM PDT



Windownaut is a lightweight and robust window resizer, mover and more that aims to have a very small footprint. It allows you to easily resize, move and add a variety of new control options to almost all app windows.

Features

  • Window quadrant/corner-aware resizing.
  • Eight edge rapid window snapping. Simply drag window to an edge and it will resize into one of eight sizes.
  • Shortcuts for window layouts including a rapid "Cycle layouts" option and "Move to next screen".
  • Move and resize windows from anywhere on the window and without activation.
  • Easy to use traffic control buttons customization: 1- Show a visual window layout menu, 2- Quit, not merely close, an app. 3-Force quit an app. 4- Open Finder showing document associated with a document window.
Does not use any system hacks or tricks. It works using standard magical Apple APIs.



Version 1.0:
  • Windownaut is now officially out of beta.
  • If you wish to use the previous, beta version (which is valid up to 29 May), do not upgrade to this version.
  • This version has a 14-day trial limit.
  • [FIX] Minor bugs and cosmetic fixes


  • Mac OS X 10.6 or later


Download Now

MoneyMoney 1.3.0 - German banking application.. (Commercial)

Posted: 24 Apr 2012 02:58 AM PDT



MoneyMoney is the elegant way to keep track of your German bank accounts and to do bank transfers within Germany. Interactive account statements and precise infographics show all your finances at a glance.

IMPORTANT: Currently only GERMAN BANK ACCOUNTS are fully supported (requires HBCI+/FinTS with PIN/TAN). PayPal balance and transactions import DOES WORK internationally.

Because the user interface is in English, MoneyMoney is ideal in case you have a German bank account and you're not comfortable with the German language.

MoneyMoney skips the cumbersome log-in to bank websites. Using HBCI+/FinTS and PIN/TAN technology, MoneyMoney supports most banks in Germany that do not require a chip card for online banking. With our new Web Banking engine, MoneyMoney can be extended with international financial services through Lua scripts. Please see www.moneymoney-app.com/api/webbanking for details.

BANK TRANSFERS, SCHEDULED TRANSFERS, AND STANDING ORDERS

The sleek payment window fits next to your mail app, your browser, or a PDF invoice. With our smart paste feature, you can turn an unstructured text block of payment info into a sendable bank transfer in one go.

STAY UP TO DATE

How much money do I spend per quarter? How much money have I accumulated over the last year? How much do I draw out at ATMs? The infographics in MoneyMoney show your account details better than any simple list.

ROBUST SECURITY

All information is transferred in a tap-proof connection between your Mac and the bank. MoneyMoney saves all your transactions and account credentials in a reliable database. You can optionally protect the database with a personal password. More details at www.moneymoney-app.com/security

FIND INSTANTLY

MoneyMoney allows you to filter and search all your transactions. Enter a search term, change the time period, or filter by transaction type. It will take only seconds to find things that you would still not have found after minutes of using your web browser.

SUPPORTED BANKS:

MoneyMoney supports many German banks, but ONLY GERMAN BANK ACCOUNTS ARE FULLY SUPPORTED! If your bank's data centre supports HBCI+ 2.2 with PIN/TAN 1.01 extension or FinTS 3.0 with PIN/TAN, MoneyMoney should work. Please visit http://moneymoney-app.com to find out whether your bank is supported. Thank you!

Version 1.3.0:

More Banking

  • Standing orders and scheduled transfers are now possible.
  • Pending transactions are now shown.

More Banks

  • API for developers: Simple web scraping for financial services that do not support the HBCI protocol
  • Imports balance and transactions from PayPal
  • Imports balance and transactions from Commerzbank
  • Supports credit cards of DKB
  • Supports credit cards of LBB (Amazon, Air Berlin, ADAC)
  • Supports credit cards of Valovis Bank
  • Supports credit cards of HypoVereinsbank

More Printing

  • Printing of bank transfers
  • Printing of single transactions

More Exports

  • Real Excel export (XLS binary and XML)
  • Extended CSV export
  • New: OFX export (Open Financial Exchange Format)
  • Can be expanded with more export formats through Lua scripts

More Screen

  • Mac OS X 10.7 full screen support

More Polish

  • Redesigned account setup
  • Redesigned payment window

More at a Glance

  • Redesigned Dashboard: More space for accounts. Showing currency.
  • New transactions are shown in the status item's account list
  • Clicking on an account in the status item's account list opens the account in the main window.
  • Clicking the bar chart jumps to the corresponding date.
  • Time period can be set to any start and end dates.

More Technology

  • MoneyMoney can now be extended with more financial services through the new script-controlled Web Banking engine.
  • Account properties: A previously saved PIN can now be deleted.
  • Account properties: SSL certificates now show the complete SSL certificate chain.
  • After submitting a payment, the corresponding account is refreshed automatically.
  • Showing the bank transfer button only when there is at least one account that supports HBCI payments.
  • OCSP queries don't block the GUI any more.
  • Allow ~ in passwords (even though this is off the HBCI spec)
  • Extract account numbers from unstructured transaction purpose (Sparda bank)
  • Transaction duplicates can now be removed by Option-Ctrl-clicking the selected transactions.
  • When upgrading the database, the parameters for certain banks are updated automatically from HBCI+ 2.2 to FinTS 3.0 (if the bank supports this)
  • The account setup dialog now knows the German bank codes for İşbank.
  • Updated SSL certificates for Fiducia and GAD.
  • Fix: DKB only allows the first five characters of a password to be submitted. This should now work properly.
  • If an account supports only internal transfers, now all accounts with the same bank code are shown��"even if they are accessed through different credentials.


  • Mac OS X 10.6 or later
  • German bank account with HBCI+/FinTS protocol and PIN/TAN method.


Download Now

This posting includes an audio/video/photo media file: Download Now

Vitamin-R 1.79 - Personal productivity tool.. (Shareware)

Posted: 24 Apr 2012 02:33 AM PDT



Vitamin-R creates the optimal conditions for your brain to work at its best by structuring your work into short bursts of distraction-free, highly focused activity alternating with opportunities for renewal, reflection and intuition.

The built-in task logging and statistics features create a positive momentum towards productivity by providing visible feedback on your progress and achievements.

Time Slice Your Work

Vitamin-R breaks down large, vaguely defined tasks into a series of short "time slices" of between 10 and 30 minutes, each with specific, easily reachable and actionable objectives. During these time slices it keeps you focused on accomplishing only this one objective and provides you with mechanisms for dealing with interruptions, poor concentration, etc.

Get Started

Vitamin-R concentrates on getting you started allowing you to break through the resistance of procrastination and create a positive feedback loop of small achievements that get you closer to your ultimate aims. You will experience less stress caused by looming deadlines and a lack of clear direction, thus enabling you to enjoy guilt-free breaks that allow your intuition and creativity to emerge.

Find Your Rhythm

Each one of us is different. Finding out what works best for you is the key to true productivity. Vitamin-R helps you by giving you the tools to gain more awareness of how you spend your time, what works for you and what does not. Armed with this new knowledge, you can eliminate unproductive work patterns and discover the work rhythm that suits you best.

Get It Out of Your Head Quickly

Did you know that your short term memory can only hold 4-6 "chunks" of information? The slightest interruption and it's all gone and you have to start from scratch. That's why Vitamin-R provides you with the "Now & Later Board", complete with FastType magic, to give you a place to quickly dump all those things that go through your head and allow you to quickly return to your task.

Make It Your Own

Vitamin-R plugs into your life rather than trying to take it over. You can use it occasionally to overcome procrastination or mental blocks or re-organize your entire working life around the concepts that it embodies. It complements rather than replaces traditional to-do list managers, such as Things or OmniFocus for which direct integrations exist.

Now With Cloud Synching!

If you routinely work on multiple Macs, you willlove Vitamin-R's new ability to effortlessly synch your time slice log across the cloud using the free Dropbox service. Setup is as easy as ticking a checkbox.

Recapture the lost of art of joyful concentration. Overcome procrastination. Rediscover the motivation within yourself.



Version 1.79:
  • Features a completely rewritten help book.
  • fixes a minor issue with the NeuroSky MindWave integration
  • fixes Finder window closing
  • other minor improvements and fixes


  • Mac OS X 10.6 or later


Download Now

Crystals, Vol. 2, Pages 327-337: Halogen Bonding Interactions in DDQ Charge Transfer Salts with Iodinated TTFs

Posted: 24 Apr 2012 12:00 AM PDT

Oxidation of 3,4-ethylenedithio-3'-iodo-tetrathiafulvalene (EDT-TTF-I) and 3,4-ethylenedithio-3',4'-diiodo-tetrathiafulvalene (EDT-TTF-I2) with DDQ afforded two different salts formulated as (EDT-TTF-I)(DDQ) and (EDT-TTF-I2)2(DDQ)·(CH3CN), both characterized with a full charge transfer to the DDQ acceptor moiety and by short and linear halogen bonding interactions between the iodine atom as halogen bond donor, and the carbonyl oxygen or the nitrile nitrogen atoms of reduced DDQ.

Energies, Vol. 5, Pages 1245-1270: A Low-Carbon Dispatch Model in a Wind Power Integrated System Considering Wind Speed Forecasting and Energy-Environmental Efficiency

Posted: 24 Apr 2012 12:00 AM PDT

This paper introduces the "Energy-Environmental Efficiency" concept of building a low-carbon dispatch model of wind-incorporated power systems from the perspective of environmental protection and low-carbon dispatch promotion based on the existing economic environmental dispatch. A rolling auto-regressive and moving-average model is adopted to forecast wind speeds for the next 24 h and reduce the disadvantages brought about to the power system dispatch by wind speed fluctuations. A fuzzy satisfaction-maximizing approach is employed to convert the multi-objective decision-making problem in the low-carbon dispatch model into a single nonlinear one. Particle swarm optimization with a simulated annealing algorithm hybrid is used for better solutions. Simulation results show that the energy-environmental efficiency concept benefits the optimization of the proposed power system dispatch, and the proposed low-carbon dispatch model is reasonable and practical.

Robotics, Vol. 1, Pages 1-2: Robotics — Inspired from Nature

Posted: 24 Apr 2012 12:00 AM PDT

It is my great pleasure to welcome you to a new open access journal, Robotics, which is dedicated to both the foundations of artificial intelligence, bio-mechanics, mechatronics and control theories, and the real-world applications of robotic perception, cognition and actions. This includes the innovative scientific trends, and discovery resulting from solving new challenges in the field of robotics. Its open access and rapid dissemination are the unique features separating this journal from all existing journals dedicated to robotics. [...]

Religions, Vol. 3, Pages 339-343: False Gods and the Two Intelligent Questions of Metapsychiatry

Posted: 24 Apr 2012 12:00 AM PDT

This paper explains how the spiritual teaching known as Metapsychiatry, developed by psychiatrist Thomas Hora, employs two questions as its focal educational method. Those questions facilitate phenomenological discernment of the source (i.e. the meaning) of our problems in living and help students and patients to understand the real nature of God. Perceiving our existentially invalid attachments and the inevitable suffering they produce encourages us to seek inspiration from God.

Cisco Jabber Video for TelePresence 4.4.3.14479 - Cloud-based collaborative workspace. . (Commercial)

Posted: 24 Apr 2012 02:12 AM PDT



Cisco Jabber Video for TelePresence (Jabber Video) is an application that extends the reach of telepresence. Jabber Video works with a compatible PC or Mac and a webcam or Cisco TelePresence PrecisionHD camera to provide high-definition video communications to more people, on more devices, from more places. Jabber Video can connect to telepresence systems, resulting in a wider community of colleagues, partners, and business customers.

Version 4.4.3.13379:

The following issues were found in previous releases and were resolved in 4.4:

  • 01 Page 1 of 6Open issues
  • Cisco Jabber Video for TelePresence Release Notes (4.4) Page 2 of 6
  • Identifier Description
  • Improved reliability of ICE when using TCP relay.
  • Cease bandwidth adaptation when no quality improvement results.
  • Fixed typographical error in "Unable to connect" error message.
  • Resolved issue causing bandwidth adaptation to fail in constant packet loss situations.
  • Resolved issue where TURN probing would sometimes hang when reaching open port 80.
  • When ICE is enabled and TURN server port allocation fails due to VPN connection, allocation will now time out faster.
  • Improved handling of incomplete provisioning templates. Related stability issue resolved.
  • Corrected handling of the pre-configuration option to make network settings unavailable to users ("hideadvancedlogin), improved information to user when network settings are controlled by administrator and not editable.
  • Downgrade option using MSIExec is not supported by Jabber Video and has now been disabled.
  • Restricted bandwidth probing from going beyond the maximum provisioned outgoing bandwidth.
  • Resolved issue causing poor media quality and call disruption in some scenarios involving ICE on lower bandwidths.
  • Improved handling of heavy packet loss on call setup.
  • Solved issue that would sometimes interrupt the download of an upgrade or downgrade.
  • Resolved multiple stability issues.

Open issues:

  • The following issues apply to this version of Cisco Jabber Video for TelePresence.
  • Windows XP only: Sharing Internet Explorer 6.0 or 8.0 as a presentation makes the presentation video flash.
  • When user ends a call while having another call on hold, the presence status erroneously changes to "Online". When the second call is resumed, the status remains "Online".

      Mac OS X:

      • Be sure to install and start up Jabber Video before removing Movi, as settings are imported on first startup.
      • When installing:
        • Jabber Video installs itself as a new application alongside Cisco TelePresence Movi
        • Jabber Video registers itself as the default SIP protocol handler.
        • The program bundle identifier is now com.cisco.JabberVideo.
      • When Jabber Video is launched:
        • Preferences, Favorites, and History are imported from Movi.
        • Stored passwords are not imported and must be re-entered.


      • Mac OS X 10.6 or later
      • Cisco TelePresence Management Suite (Cisco TMS) 12.6 or later
      • Cisco Video Communication Server (Cisco VCS) X5.2 or later
      • X6.0 or later for ICE support
      • X6.1 or later for NTLM support
      • IP network connection (broadband, LAN, wireless). At least 24 kb/s is required for an audio connection. For a video connection, the recommended minimum is 128 kb/s.


      Download Now

Roccat Browser 2.4 - Fast Web browser with a variety of features.. (Free)

Posted: 24 Apr 2012 02:29 AM PDT



Roccat Browser is an amazing browser from the fludium family. Roccat Browser is an amazingly fast Web browser, which has some great features such as:
  • VisiTabs which gives a preview of the website in the tab.
  • Navigate Launchers- assign letters or words to navigate to webpages, there are already many preloaded ones
  • Ad-Remover built within the engine
  • Great internal engine effects, purple glows on inputs, hold down on text field for 5 seconds for them to enlarge.
  • Email-Previewer; tells you when a link is an email link and tells you the link
  • Change User Agents- View sites which need other browser, view apples videos which require Safari etc...
  • A choice of VisiTabs or normal tabs or both, a bookmarks bar which fully supports bookmarklets
  • Downloads files and programs really easily and fast
  • Gets 100/100 in the Acid3 test
  • New Download Manager and now has FullScreen Mode
  • Lovebyt.es integration for instant URL shortening.
  • Undercover Browsing
  • Social page sharing / online email sharing
  • eBuddy Widget (chat with your facebook, msn, yahoo messenger, ICQ and aim friends no matter what tab you are on)
  • English, French and German localization
  • Ability to Import Bookmarks
  • Mac OS X 10.7 Lion fullscreen support
  • Roccat Munch cookie management
  • Auto reloader (5, 10, 15 or 30 seconds)
  • The amazing RClouds (beta) which allows you to backup your settings, open tabs, imported bookmarks, bookmarks, navigate launchers, history and much more. RClouds allows you to restore your backups to any Mac so your browsing session can be anywhere you want it to be!
  • RClouds Reset allows you to reset your browser to factory settings (especially useful when you've restored your data to a public computer.
  • Cinnamon on the RClouds now means faster updating as it intelligently looks for the servers with the least amount of traffic.
  • We have even purchased the rights of exclusivity with lovebyt.es so now only Roccat users can use the service!
Why not try Cookie Stumbler to manage Roccat's cookies in the most secure way?

Version 2.4:
  • 8 Bug fixes including RClouds bug fixes and the on going bug which still added a bookmark when the cancel option was pressed.
  • New security update
  • Minor design changes to RClouds, you can now also login to Lovebyt.es with your RuneID/RCloudID - New add bookmark, add new tab and check version buttons added to the titlebar utilizing wasted screen estate.

    Mac OS X 10.5 or later

    Download Now

This posting includes an audio/video/photo media file: Download Now

Superbrothers: Sword & Sworcery EP Review

Posted: 23 Apr 2012 07:15 PM PDT

Superbrothers: Sword & Sworcery EP is a beautiful and enthralling adventure that feels both archetypal and unique.

     

Score: 9.0 / superb

Get the full article at GameSpot


"Superbrothers: Sword & Sworcery EP Review" was posted by Carolyn Petit on Mon, 23 Apr 2012 19:15:48 -0700

Gameplay Demo - Sniper

Posted: 23 Apr 2012 05:45 PM PDT

Hope you can duck fast, because we've got Sniper: Ghost Warrior 2 headed your way!

 

Read and Post Comments | Get the full article at GameSpot


"Gameplay Demo - Sniper" was posted by Jan on Mon, 23 Apr 2012 17:45:31 -0700

Toddler's Seek & Find: My Little Town. An interactive activity book. Screens

Posted: 23 Apr 2012 05:04 PM PDT

5 new shots posted.

     

Get the full article at GameSpot


Toddler's Seek & Find - My Animals. An interactive activity book showing zoo, farm and forest.. Screens

Posted: 23 Apr 2012 05:04 PM PDT

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