Games |
- Sensors, Vol. 12, Pages 5420-5431: A Long-Wavelength Fluorescent Squarylium Cyanine Dye Possessing Boronic Acid for Sensing Monosaccharides and Glycoproteins with High Enhancement in Aqueous Solution
- Sensors, Vol. 12, Pages 5395-5419: Fiber Sensor Systems Based on Fiber Laser and Microwave Photonic Technologies
- Sensors, Vol. 12, Pages 5380-5394: Full-Scale Prestress Loss Monitoring of Damaged RC Structures Using Distributed Optical Fiber Sensing Technology
- IJMS, Vol. 13, Pages 5338-5347: Neurotrophic Effect of Citrus Auraptene: Neuritogenic Activity in PC12 Cells
- Molecules, Vol. 17, Pages 4904-4914: Microbial Enhance of Chitosan Production by Rhizopus arrhizus Using Agroindustrial Substrates
- Molecules, Vol. 17, Pages 4896-4903: Gossypol Exhibits a Strong Influence Towards UDP-Glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-Mediated Metabolism of Xenobiotics and Endogenous Substances
- Molecules, Vol. 17, Pages 4878-4895: Kinetic Study of Oxygen Adsorption over Nanosized Au/γ-Al2O3 Supported Catalysts under Selective CO Oxidation Conditions
- Symmetry, Vol. 4, Pages 276-284: Following Knots down Their Energy Gradients
- SEAL Team 12 - Screenshots
- Apple Support Communities 1.0 - A Dashboard community widget.. (Free)
- Dashcode Tips 1.0 - A Dashboard news widget.. (Free)
- PopChar X 5.4.1 - Floating window shows available font characters.. (Shareware)
- Battle For Asciion
- Water, Vol. 4, Pages 460-473: Scenario Analysis of Nutrient Removal from Municipal Wastewater by Microalgal Biofilms
- Two more indicted in case against alleged mob boss Ligambi
- League of Lessons: The Bruiser (Part One)
- Bloodforge Review
- Video Review - Bloodforge
- World of Tanks Interview with Wargaming.net CEO
- The HotSpot - 04/26/2012
| Posted: 27 Apr 2012 12:00 AM PDT Fluorescence sensing of saccharides and glycoproteins using a boronic acid functionalized squarylium cyanine dye ("SQ-BA") is characterized in terms of synthetic, fluorometric, thermodynamic and kinetic parameters. In our previous work, this newly synthesized dye was successfully applied to the separation and quantification of Gram-positive bacteria by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF); however, the fundamental properties of the dye and its saccharide complexes still required elucidation, as presented in this paper. The dye itself forms nonemissive, soluble aggregates in aqueous solution. With the addition of a monosaccharide, the dye aggregate dissociates to form an emissive monomer accompanied by the formation of a cyclic cis-diol ester with long-wavelength emission (lex = 630 nm, lem = 660 nm). A very large fluorescence enhancement factor of 18× was observed for the sensing dye as a fructose complex at pH 10, yielding a limit of detection of 10 mM fructose. The relative order of fluorescence enhancement of SQ-BA with other monosaccharides was found to be: fructose > ribose > arabinose ≈ galactose > xylose > mannose > rhamnose > fucose ≈ glucose; and apparent affinity constants of 102.80, 102.08 and 100.86 M−1 were determined for fructose, ribose and glucose, respectively. Formation of the emissive complexes occurred within minutes, proving the kinetics of the sugar-dye interactions to be suitable for on-column labeling methods in CE-LIF. Furthermore, the sensing dye was successfully applied to glycoproteins, mucin type I–S and type III, which were detected with high sensitivity in batch aqueous solution as a result of the sugar-selective boronic acid-diol esterification as well as hydrophobic interactions. |
| Posted: 27 Apr 2012 12:00 AM PDT Fiber-optic sensors, especially fiber Bragg grating (FBG) sensors are very attractive due to their numerous advantages over traditional sensors, such as light weight, high sensitivity, cost-effectiveness, immunity to electromagnetic interference, ease of multiplexing and so on. Therefore, fiber-optic sensors have been intensively studied during the last several decades. Nowadays, with the development of novel fiber technology, more and more newly invented fiber technologies bring better and superior performance to fiber-optic sensing networks. In this paper, the applications of some advanced photonic technologies including fiber lasers and microwave photonic technologies for fiber sensing applications are reviewed. FBG interrogations based on several kinds of fiber lasers, especially the novel Fourier domain mode locking fiber laser, have been introduced; for the application of microwave photonic technology, examples of microwave photonic filtering utilized as a FBG sensing interrogator and microwave signal generation acting as a transversal loading sensor have been given. Both theoretical analysis and experimental demonstrations have been carried out. The comparison of these advanced photonic technologies for the applications of fiber sensing is carried out and important issues related to the applications have been addressed and the suitable and potential application examples have also been discussed in this paper. |
| Posted: 27 Apr 2012 12:00 AM PDT For the safety of prestressed structures, prestress loss is a critical issue that will increase with structural damage, so it is necessary to investigate prestress loss of prestressed structures under different damage scenarios. Unfortunately, to date, no qualified techniques are available due to difficulty for sensors to survive in harsh construction environments of long service life and large span. In this paper, a novel smart steel strand based on the Brillouin optical time domain analysis (BOTDA) sensing technique was designed and manufactured, and then series of tests were used to characterize properties of the smart steel strands. Based on prestress loss principle analysis of damaged structures, laboratory tests of two similar beams with different damages were used to verify the concept of full-scale prestress loss monitoring of damaged reinforced concrete (RC) beams by using the smart steel strands. The prestress losses obtained from the Brillouin sensors are compared with that from conventional sensors, which provided the evolution law of prestress losses of damaged RC beams. The monitoring results from the proposed smart strand can reveal both spatial distribution and time history of prestress losses of damaged RC beams. |
| Posted: 27 Apr 2012 12:00 AM PDT The activation of extracellular signal-regulated kinases (ERK) leads to a number of cellular changes associated with the development of long-term memory. Using cultured cortical neurons, we previously showed that the n-hexane extract prepared from the peels of Citrus grandis (Kawachi bankan) induces the activation of ERK1/2 and that one of the compounds with this ability in the extract is 3,5,6,7,8,3′,4′-heptamethoxyflavone (HMF), a Citrus polymethoxyflavone. In fact, we found that HMF has the ability to rescue mice from drug-induced learning impairment. This hexane extract contains auraptene (AUR), a coumarin derivative with a monoterpene unit, together with HMF. The present study was designed to investigate the effect of AUR in vitro. Our results show that 1) AUR had the ability to induce the activation of ERK1/2 in not only cortical neurons but also the rat pheochromocytoma cell line (PC12 cells), which is a model system for studies on neuronal proliferation and differentiation; and 2) AUR had the ability to promote neurite outgrowth from PC12 cells. |
| Posted: 27 Apr 2012 12:00 AM PDT This study investigated the potential of Rhizopus arrhizus UCP 402 for producing chitosan using corn steep liquor and honey as agroindustrial nitrogen and carbon sources. A complete factorial design was used to assess the improved biomass and chitosan production. The results were evaluated using Pareto charts (Statistica 7.0 software). The chitosan obtained was characterized by X-ray diffraction. The cristallinity index (IC), and infrared spectroscopy (FTIR) were used to evaluate the degree of deacetylation (DD %). The morphological aspects of the R. arrhizus were evaluated by measuring the diameter of the colonies by light microscopy. The results obtained showed higher biomass and chitosan yields (20.61 g/L and 29.3 mg/g), respectively, in the selected assays. The characterization of the macromolecular arrangement of chitosan showed a crystallinity index compatible with the literature, and the infrared peaks confirmed a degree of 86%. The experimental data obtained suggest that adding honey to corn steep liquor is a promising way to improve microbiological chitosan production. |
| Posted: 27 Apr 2012 12:00 AM PDT Gossypol, the polyphenolic constituent isolated from cottonseeds, has been used as a male antifertility drug for a long time, and has been demonstrated to exhibit excellent anti-tumor activity towards multiple cancer types. The toxic effects of gossypol limit its clinical utilization, and enzyme inhibition is an important facet of this. In the present study, in vitro human liver microsomal incubation system supplemented with UDPGA was used to investigate the inhibition of gossypol towards UGT1A1, 1A9 and 2B7-mediated metabolism of xenobiotics and endogenous substances. Estradiol, the probe substrate of UGT1A1, was selected as representative endogenous substance. Propofol (a probe substrate of UGT1A9) and 3'-azido-3'-deoxythimidine (AZT, a probe substrate of UGT2B7) were employed as representative xenobiotics. The results showed that gossypol noncompetitively inhibits UGT-mediated estradiol-3-glucuronidation and propofol O-glucuronidation, and the inhibition kinetic parameters (Ki) were calculated to be 34.2 and 16.4 μM, respectively. Gossypol was demonstrated to exhibit competitive inhibition towards UGT-mediated AZT glucuronidation, and the inhibition kinetic parameter (Ki) was determined to be 14.0 μM. All these results indicated that gossypol might induce metabolic disorders of endogenous substances and alteration of metabolic behaviour of co-administered xenobiotics through inhibition of UGTs' activity. |
| Posted: 27 Apr 2012 12:00 AM PDT O2 adsorption is a key process for further understanding the mechanism of selective CO oxidation (SCO) on gold catalysts. Rate constants related to the elementary steps of O2 adsorption, desorption and surface bonding, as well as the respective activation energies, over a nanosized Au/γ-Al2O3 catalyst, were determined by Reversed-Flow Inverse Gas Chromatography (RF-IGC). The present study, carried-out in a wide temperature range (50–300 °C), both in excess as well as in the absence of H2, resulted in mechanistic insights and kinetic as well as energetic comparisons, on the sorption processes of SCO reactants. In the absence of H2, the rate of O2 binding, over Au/γ-Al2O3, drastically changes with rising temperature, indicating possible O2 dissociation at elevated temperatures. H2 facilitates stronger O2 bonding at higher temperatures, while low temperature binding remains practically unaffected. The lower energy barriers observed, under H2 rich conditions, can be correlated to O2 dissociation after hydrogenation. Although, H2 enhances both selective CO reactant's desorption, O2 desorption is more favored than that of CO, in agreement with the well-known mild bonding of SCO reactant's at lower temperatures. The experimentally observed drastic change in the strength of CO and O2 binding is consistent both with well-known high activity of SCO at ambient temperatures, as well as with the loss of selectivity at higher temperatures. |
| Symmetry, Vol. 4, Pages 276-284: Following Knots down Their Energy Gradients Posted: 27 Apr 2012 12:00 AM PDT This paper details a series of experiments in searching for minimal energy configurations for knots and links using the computer program KnotPlot. |
| Posted: 27 Apr 2012 03:35 AM PDT SEAL Team 12 is a top down, twin stick shooter, where you can play as a member of the Elite SEAL Team 12. The game pits the player against a previously unknown group called the 'Guardians Of Devastation' (GOD) who are planning on devastating the world. Game features: - Single Player or local co-op play - Fast paced arcade twin-stick shooter - Piles of weapons to choose from - Evil Enemies and larger than average size Bosses - Epic Storyline with cheesy voice acting - High score tracking - Custom Soundtrack (XBox) - DRM Free (on PC, we hate that stuff) |
| Apple Support Communities 1.0 - A Dashboard community widget.. (Free) Posted: 27 Apr 2012 02:33 AM PDT  Apple Support Communities helps you find and share solutions with Apple users around the world, right from your Mac OS X Dashboard.
Download Now This posting includes an audio/video/photo media file: Download Now |
| Dashcode Tips 1.0 - A Dashboard news widget.. (Free) Posted: 27 Apr 2012 02:25 AM PDT  Dashcode Tips gives you developer tips, news and sample codes right in to your Mac OS X Dashboard.
Download Now This posting includes an audio/video/photo media file: Download Now |
| PopChar X 5.4.1 - Floating window shows available font characters.. (Shareware) Posted: 27 Apr 2012 02:40 AM PDT  PopChar X is a utility application that lets you insert special characters, accented letters, umlauts, etc. from all installed fonts into your documents. You never need to search for and remember keystrokes any longer. Just pop up the PopChar window, click the desired character, and the character appears in your current document. If a font contains Unicode characters, you can see all of them, neatly arranged in the standard Unicode categories. Features:
Version 5.4.1:
Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 24 Apr 2012 10:24 AM PDT Platform: Flash —  Want a solid retro arcade shooter? ASCII and you'll receive Battle for Asciion, by Relevo Video Games. Designed with a lot of love for its textual aesthetic, Battle for Asciion is a solid and challenging shoot-em-up, though hampered by its required button-mashing. Tagged as: arcade, ascii, browser, flash, free, game, linux, mac, rating-g, relevovideogames, retro, scifi, shooter, space, text, unique, upgrades, windows |
| Posted: 27 Apr 2012 12:00 AM PDT Microalgae can be used for the treatment of municipal wastewater. The application of microalgal biofilms in wastewater treatment systems seems attractive, being able to remove nitrogen, phosphorus and COD from wastewater at a short hydraulic retention time. This study therefore investigates the area requirement, achieved effluent concentrations and biomass production of a hypothetical large-scale microalgal biofilm system treating municipal wastewater. Three scenarios were defined: using microalgal biofilms: (1) as a post-treatment; (2) as a second stage of wastewater treatment, after a first stage in which COD is removed by activated sludge; and (3) in a symbiotic microalgal/heterotrophic system. The analysis showed that in the Netherlands, the area requirements for these three scenarios range from 0.32 to 2.1 m2 per person equivalent. Moreover, it was found that it was not possible to simultaneously remove all nitrogen and phosphorus from the wastewater, because of the nitrogen:phosphorus ratio in the wastewater. Phosphorus was limiting in the post-treatment scenario, while nitrogen was limiting in the two other scenarios. Furthermore, a substantial amount of microalgal biomass was produced, ranging from 13 to 59 g per person equivalent per day. These findings show that microalgal biofilm systems hold large potential as seasonal wastewater treatment systems and that it is worthwhile to investigate these systems further. |
| Two more indicted in case against alleged mob boss Ligambi Posted: 27 Apr 2012 12:43 AM PDT Jailed mob boss Joseph "Uncle Joe" Ligambi illegally collected more than $224,000 in medical benefits for himself and his family while holding a no-show job at a South Philadelphia trash-disposal company, according to an expanded federal indictment unsealed Thursday. |
| League of Lessons: The Bruiser (Part One) Posted: 26 Apr 2012 10:53 PM PDT In this next instalment in our ongoing League of Legends guide, we explore the basics of the bruiser role. It's clobberin' time!
Get the full article at GameSpot "League of Lessons: The Bruiser (Part One)" was posted by Joshua Lim on Thu, 26 Apr 2012 22:53:56 -0700 |
| Posted: 26 Apr 2012 07:45 PM PDT Bloodforge's striking brutality doesn't stand a chance of overcoming its crushingly dull gameplay.
Score: 3.0 / bad Get the full article at GameSpot "Bloodforge Review" was posted by Carolyn Petit on Thu, 26 Apr 2012 19:45:23 -0700 |
| Posted: 26 Apr 2012 07:44 PM PDT Carolyn Petit wades through a bloodbath of annoying problems to bring you this review for Bloodforge.
Read and Post Comments | Get the full article at GameSpot "Video Review - Bloodforge" was posted by JimM on Thu, 26 Apr 2012 19:44:51 -0700 |
| World of Tanks Interview with Wargaming.net CEO Posted: 26 Apr 2012 06:20 PM PDT GameSpot Asia's Jonathan Toyad has a chat with Victor Kislyi about World of Tank's place in e-sports and even a little bit about World of Warplanes. All in the dark confines of the underground bunker of Fort Canning, Singapore.
Read and Post Comments | Get the full article at GameSpot "World of Tanks Interview with Wargaming.net CEO" was posted by edmondt on Thu, 26 Apr 2012 18:20:51 -0700 |
| Posted: 26 Apr 2012 05:57 PM PDT GameSpot's original podcast rides off into the sunset with a look at Prototype 2 and Trials Evolution.
Get the full article at GameSpot "The HotSpot - 04/26/2012" was posted by Brendan Sinclair on Thu, 26 Apr 2012 17:57:53 -0700 |
| You are subscribed to email updates from Games To stop receiving these emails, you may unsubscribe now. | Email delivery powered by Google |
| Google Inc., 20 West Kinzie, Chicago IL USA 60610 | |
Комментариев нет:
Отправить комментарий