Games |
- The 9 weirdest video game uses of perfectly normal licenses
- Gothic Fiction: Dark Saga 1.0.0 - Rescue your daughter from evil in this action/adventure game. (Demo)
- Remote Sensing, Vol. 5, Pages 1274-1291: Estimation of Leaf Area Index Using DEIMOS-1 Data: Application and Transferability of a Semi-Empirical Relationship between two Agricultural Areas
- Remote Sensing, Vol. 5, Pages 1258-1273: Structural Uncertainty in Model-Simulated Trends of Global Gross Primary Production
- Abalone - Screenshots
- iFuntastic 6.6.5 - Utility to customize your iPhone (beta). (Demo)
- Unstoppabot - Screenshots
- Sensors, Vol. 13, Pages 3432-3444: Chromium and Ruthenium-Doped Zinc Oxide Thin Films for Propane Sensing Applications
- Bust Out the Brooms: Team PokerStars Sweeps The Professionals
- Sensors, Vol. 13, Pages 3409-3431: Spatio-Temporal Saliency Perception via Hypercomplex Frequency Spectral Contrast
- Sensors, Vol. 13, Pages 3394-3408: Using a Standing-Tree Acoustic Tool to Identify Forest Stands for the Production of Mechanically-Graded Lumber
- IJMS, Vol. 14, Pages 5817-5841: Chronobiology of Melatonin beyond the Feedback to the Suprachiasmatic Nucleus—Consequences to Melatonin Dysfunction
- IJMS, Vol. 14, Pages 5806-5816: Preclinical Activity of Simvastatin Induces Cell Cycle Arrest in G1 via Blockade of Cyclin D-Cdk4 Expression in Non-Small Cell Lung Cancer (NSCLC)
- FreeMan 1.2.5 - Monitors and frees up RAM. (Commercial)
- FLV Spider 3.1.20 - Capture and save online video. (Shareware)
- DCommander 1.0.8 - Advanced two-pane file manager. (Commercial)
- CCN X 3.43 - PIM with calendar, notes, digital clock, and much more. (Demo)
- IJMS, Vol. 14, Pages 5784-5805: Reaction of Stabilized Criegee Intermediates from Ozonolysis of Limonene with Water: Ab Initio and DFT Study
- IJMS, Vol. 14, Pages 5775-5783: Exploiting BSA to Inhibit the Fibrous Aggregation of Magnetic Nanoparticles under an Alternating Magnetic Field
- IJMS, Vol. 14, Pages 5765-5774: Quick, Selective and Reversible Photocrosslinking Reaction between 5-Methylcytosine and 3-Cyanovinylcarbazole in DNA Double Strand
The 9 weirdest video game uses of perfectly normal licenses Posted: 12 Mar 2013 05:14 AM PDT FIST OF THE NORTH STAR: SNOWBOARD CHALLENGE! |
Posted: 12 Mar 2013 04:47 AM PDT Gothic Fiction: Dark Saga pits you and your daughter against a cursed school! After moving to a small town in rural England, you and your daughter, Hannah, head out to visit a local school. But the brochure didn't mention anything about the ancient evil lurking there, waiting for one last soul to complete her insidious plan. Can you rescue Hannah before she becomes part of the school's terrible legacy? Features:
OS X 10.5.8 or later Download Now |
Posted: 12 Mar 2013 12:00 AM PDT This work evaluates different procedures for the application of a semi-empirical model to derive time-series of Leaf Area Index (LAI) maps in operation frameworks. For demonstration, multi-temporal observations of DEIMOS-1 satellite sensor data were used. The datasets were acquired during the 2012 growing season over two agricultural regions in Southern Italy and Eastern Austria (eight and five multi-temporal acquisitions, respectively). Contemporaneous field estimates of LAI (74 and 55 measurements, respectively) were collected using an indirect method (LAI-2000) over a range of LAI values and crop types. The atmospherically corrected reflectance in red and near-infrared spectral bands was used to calculate the Weighted Difference Vegetation Index (WDVI) and to establish a relationship between LAI and WDVI based on the CLAIR model. Bootstrapping approaches were used to validate the models and to calculate the Root Mean Square Error (RMSE) and the coefficient of determination (R2) between measured and predicted LAI, as well as corresponding confidence intervals. The most suitable approach, which at the same time had the minimum requirements for fieldwork, resulted in a RMSE of 0.407 and R2 of 0.88 for Italy and a RMSE of 0.86 and R2 of 0.64 for the Austrian test site. Considering this procedure, we also evaluated the transferability of the local CLAIR model parameters between the two test sites observing no significant decrease in estimation accuracies. Additionally, we investigated two other statistical methods to estimate LAI based on: (a) Support Vector Machine (SVM) and (b) Random Forest (RF) regressions. Though the accuracy was comparable to the CLAIR model for each test site, we observed severe limitations in the transferability of these statistical methods between test sites with an increase in RMSE up to 24.5% for RF and 38.9% for SVM. |
Posted: 12 Mar 2013 12:00 AM PDT Projected changes in the frequency and severity of droughts as a result of increase in greenhouse gases have a significant impact on the role of vegetation in regulating the global carbon cycle. Drought effect on vegetation Gross Primary Production (GPP) is usually modeled as a function of Vapor Pressure Deficit (VPD) and/or soil moisture. Climate projections suggest a strong likelihood of increasing trend in VPD, while regional changes in precipitation are less certain. This difference in projections between VPD and precipitation can cause considerable discrepancies in the predictions of vegetation behavior depending on how ecosystem models represent the drought effect. In this study, we scrutinized the model responses to drought using the 30-year record of Global Inventory Modeling and Mapping Studies (GIMMS) 3g Normalized Difference Vegetation Index (NDVI) dataset. A diagnostic ecosystem model, Terrestrial Observation and Prediction System (TOPS), was used to estimate global GPP from 1982 to 2009 under nine different experimental simulations. The control run of global GPP increased until 2000, but stayed constant after 2000. Among the simulations with single climate constraint (temperature, VPD, rainfall and solar radiation), only the VPD-driven simulation showed a decrease in 2000s, while the other scenarios simulated an increase in GPP. The diverging responses in 2000s can be attributed to the difference in the representation of the impact of water stress on vegetation in models, i.e., using VPD and/or precipitation. Spatial map of trend in simulated GPP using GIMMS 3g data is consistent with the GPP driven by soil moisture than the GPP driven by VPD, confirming the need for a soil moisture constraint in modeling global GPP. |
Posted: 12 Mar 2013 05:02 AM PDT In addition to playing the challenge mode against the game's highly developed artificial intelligence, you can also play Abalone in multiplayer mode with your friends. Move your marbles together on the same phone or tablet. Reckon you have got what it takes to become a champion? Take a crack at the freeplay mode and pit your wits against over 30 official competition variations, including the Swiss daisy, the Alien and the Fujiyama… And if that fails to satisfy your appetite for crazy challenges, create your own boards with the level editor. Features : - Voted Game of the Decade at the International Games Festival in Cannes and recipient of the Mensa Select award by American Mensa. - Challenge mode: 60 progressively difficult challenges for honing your strategic skills. - Freeplay mode with over 30 official variations. - Multiplayer mode on the same device for challenging your friends. - Up to 15 bonus levels to be unlocked by the most dedicated players. - Enhance your Abalone experience by unlocking achievements. |
iFuntastic 6.6.5 - Utility to customize your iPhone (beta). (Demo) Posted: 12 Mar 2013 03:36 AM PDT iFuntastic is an application for Mac which lets you customize your iOS device's user interface and copy files to and from the device. Some functionality is available to out-of-the-box devices (custom ringtones (phones only,) use as a USB Storage Device, copying screenshots and wallpaper,) but the really cool stuff requires the phone to be jailbroken (see below.) You can download the application for free and explore it, but to actually do something useful, you will need to activate one or more feature levels. Activation usually requires a purchase through PayPal (account not required,) but may also be accomplished with promotional activation codes (if available.) Version 6.6.5 (beta 19):
Download Now This posting includes an audio/video/photo media file: Download Now |
Posted: 12 Mar 2013 04:43 AM PDT Features: -An adorable, hand-drawn art-style -14 chapters of increasing difficulty -More than 70 puzzles -An endless "Infinite Mode" -ROBOTS! -Famous quotations and dumb jokes mere moments apart -Game Centre integration -More modes, bonus stages and unlockables to come very soon |
Posted: 12 Mar 2013 12:00 AM PDT Chromium and ruthenium-doped zinc oxide (ZnO:Cr) and (ZnO:Ru) thin solid films were deposited on soda-lime glass substrates by the sol-gel dip-coating method. A 0.6 M solution of zinc acetate dihydrate dissolved in 2-methoxyethanol and monoethanolamine was used as basic solution. Chromium (III) acetylacetonate and Ruthenium (III) trichloride were used as doping sources. The Ru incorporation and its distribution profile into the films were proved by the SIMS technique. The morphology and structure of the films were studied by SEM microscopy and X-ray diffraction measurements, respectively. The SEM images show porous surfaces covered by small grains with different grain size, depending on the doping element, and the immersions number into the doping solutions. The sensing properties of ZnO:Cr and ZnO:Ru films in a propane (C3H8) atmosphere, as a function of the immersions number in the doping solution, have been studied in the present work. The highest sensitivity values were obtained for films doped from five immersions, 5.8 and 900, for ZnO:Cr and ZnO:Ru films, respectively. In order to evidence the catalytic effect of the chromium (Cr) and ruthenium (Ru), the sensing characteristics of undoped ZnO films are reported as well. |
Bust Out the Brooms: Team PokerStars Sweeps The Professionals Posted: 12 Mar 2013 02:49 AM PDT What started as a tweet, ended in a sweep at EPT London , as Team PokerStars prevailed over The Professionals three to nil on Sunday. This posting includes an audio/video/photo media file: Download Now |
Posted: 12 Mar 2013 12:00 AM PDT Salient object perception is the process of sensing the salient information from the spatio-temporal visual scenes, which is a rapid pre-attention mechanism for the target location in a visual smart sensor. In recent decades, many successful models of visual saliency perception have been proposed to simulate the pre-attention behavior. Since most of the methods usually need some ad hoc parameters or high-cost preprocessing, they are difficult to rapidly detect salient object or be implemented by computing parallelism in a smart sensor. In this paper, we propose a novel spatio-temporal saliency perception method based on spatio-temporal hypercomplex spectral contrast (HSC). Firstly, the proposed HSC algorithm represent the features in the HSV (hue, saturation and value) color space and features of motion by a hypercomplex number. Secondly, the spatio-temporal salient objects are efficiently detected by hypercomplex Fourier spectral contrast in parallel. Finally, our saliency perception model also incorporates with the non-uniform sampling, which is a common phenomenon of human vision that directs visual attention to the logarithmic center of the image/video in natural scenes. The experimental results on the public saliency perception datasets demonstrate the effectiveness of the proposed approach compared to eleven state-of-the-art approaches. In addition, we extend the proposed model to moving object extraction in dynamic scenes, and the proposed algorithm is superior to the traditional algorithms. |
Posted: 12 Mar 2013 12:00 AM PDT This study investigates how the use of a Hitman ST300 acoustic sensor can help identify the best forest stands to be used as supply sources for the production of Machine Stress-Rated (MSR) lumber. Using two piezoelectric sensors, the ST300 measures the velocity of a mechanical wave induced in a standing tree. Measurements were made on 333 black spruce (Picea mariana (Mill.) BSP) trees from the North Shore region, Quebec (Canada) selected across a range of locations and along a chronosequence of elapsed time since the last fire (TSF). Logs were cut from a subsample of 39 trees, and sawn into 77 pieces of 38 mm × 89 mm cross-section before undergoing mechanical testing according to ASTM standard D-4761. A linear regression model was developed to predict the static modulus of elasticity of lumber using tree acoustic velocity and stem diameter at 1.3 m above ground level (R2 = 0.41). Results suggest that, at a regional level, 92% of the black spruce trees meet the requirements of MSR grade 1650Fb-1.5E, whilst 64% and 34% meet the 2100Fb-1.8E and 2400Fb-2.0E, respectively. Mature stands with a TSF < 150 years had 11 and 18% more boards in the latter two categories, respectively, and therefore represented the best supply source for MSR lumber. |
Posted: 12 Mar 2013 12:00 AM PDT The mammalian circadian system is composed of numerous oscillators, which gradually differ with regard to their dependence on the pacemaker, the suprachiasmatic nucleus (SCN). Actions of melatonin on extra-SCN oscillators represent an emerging field. Melatonin receptors are widely expressed in numerous peripheral and central nervous tissues. Therefore, the circadian rhythm of circulating, pineal-derived melatonin can have profound consequences for the temporal organization of almost all organs, without necessarily involving the melatonin feedback to the suprachiasmatic nucleus. Experiments with melatonin-deficient mouse strains, pinealectomized animals and melatonin receptor knockouts, as well as phase-shifting experiments with explants, reveal a chronobiological role of melatonin in various tissues. In addition to directly steering melatonin-regulated gene expression, the pineal hormone is required for the rhythmic expression of circadian oscillator genes in peripheral organs and to enhance the coupling of parallel oscillators within the same tissue. It exerts additional effects by modulating the secretion of other hormones. The importance of melatonin for numerous organs is underlined by the association of various diseases with gene polymorphisms concerning melatonin receptors and the melatonin biosynthetic pathway. The possibilities and limits of melatonergic treatment are discussed with regard to reductions of melatonin during aging and in various diseases. |
Posted: 12 Mar 2013 12:00 AM PDT Lung cancer is the most common cause of cancer-related death. Nonetheless, a decrease in overall incidence and mortality has been observed in the last 30 years due to prevention strategies and improvements in the use of chemotherapeutic agents. In recent studies, Simvastatin (SIM) has demonstrated anti-tumor activity, as well as potent chemopreventive action. As an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA), SIM has been shown to stimulate apoptotic cell death. In this study, an MTT assay revealed the cytotoxic activity of SIM against human large cell lung cancer (Non-small cell lung cancer; NSCLC) cells (NCI-H460); however, induced apoptosis was not observed in NCI-H460 cells. Protein expression levels of cell cycle regulating proteins Cdk4, Cyclin D1, p16 and p27 were markedly altered by SIM. Collectively, our results indicate that SIM inhibits cell proliferation and arrests NCI-H460 cell cycle progression via inhibition of cyclin-dependent kinases and cyclins and the enhancement of CDK inhibitors p16 and p27. Our findings suggest that, in addition to the known effects on hypercholesterolemia therapy, SIM may also provide antitumor activity in established NSCLC. |
FreeMan 1.2.5 - Monitors and frees up RAM. (Commercial) Posted: 12 Mar 2013 03:28 AM PDT FreeMan can speed up your Mac with a single click by freeing up system memory. FreeMan is also a memory monitor which can free up memory automatically if inactive memory reaches a preset threshold. Version 1.2.5:
OS X 10.6 or later Download Now |
FLV Spider 3.1.20 - Capture and save online video. (Shareware) Posted: 12 Mar 2013 03:15 AM PDT FLV Spider is a simple utility that allows you to capture online videos. So, if you see a cool online video, and would like to save it to your Mac or to your iPod, nothing is easier! Just run FLV Spider before you start to surf the Web. FLV Spider will automatically capture all online videos opened in a Web browser. Embedded Lossless Movie Trimmer lets you easily cut-off a portion of captured video, and Lossless Movie Joiner lets you easily join captured video/audio files into one continuous movie. Please read the help manual to learn more about these advanced tools. IMPORTANT: Only Flash videos are supported now. SilverLight videos will be supported soon.
OS X 10.4 or later Download Now |
DCommander 1.0.8 - Advanced two-pane file manager. (Commercial) Posted: 12 Mar 2013 03:10 AM PDT DCommander is a two-pane file manager that gives you full control over your computer's filesystem. Optimized for quick access and user-friendliness, DCommander provides a perfect file-management companion for new Mac users transitioning from other operating systems, as well as advanced power users who demand more control of their computer. Features include:
Version 1.0.8:
Download Now |
CCN X 3.43 - PIM with calendar, notes, digital clock, and much more. (Demo) Posted: 12 Mar 2013 02:52 AM PDT CCN X is a text-based simple-to-use mini personal information manager with many helpful components:
Version 3.43:
OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
Posted: 12 Mar 2013 12:00 AM PDT The mechanism of the chemical reaction of H2O with three stabilized Criegee intermediates (stabCI-OO, stabCI-CH3-OO and stabCIx-OO) produced via the limonene ozonolysis reaction has been investigated using ab initio and DFT (Density Functional Theory) methods. It has been shown that the formation of the hydrogen-bonded complexes is followed by two different reaction pathways, leading to the formation of either OH radicals via water-catalyzed H migration or of α-hydroxy hydroperoxide. Both pathways were found to be essential sources of atmospheric OH radical and H2O2 making a significant contribution to the formation of secondary aerosols in the Earth's atmosphere. The activation energies at the CCSD(T)/6-31G(d) + CF level of theory were found to be in the range of 14.70–21.98 kcal mol−1. The formation of α-hydroxy hydroperoxide for the reaction of stabCIx-OO and H2O with the activation energy of 14.70 kcal mol−1 is identified as the most favorable pathway. |
Posted: 12 Mar 2013 12:00 AM PDT The alternating magnetic field was discovered to be capable of inducing the fibrous aggregation of magnetic nanoparticles. However, this anisotropic aggregation may be unfavorable for practical applications. Here, we reported that the adsorption of BSA (bovine serum albumin) on the surfaces of magnetic nanoparticles can effectively make the fibrous aggregation of γ-Fe2O3 nanoparticles turn into a more isotropic aggregation in the presence of the alternating magnetic field. Also, the heating curves with and without BSA adsorption under different pH conditions were measured to show the influence of the colloidal aggregation states on the collective calorific behavior of magnetic nanoparticles. |
Posted: 12 Mar 2013 12:00 AM PDT Selective photocrosslinking reaction between 3-cyanovinylcarbazole nucleoside (CNVK) and 5-methylcytosine (mC), which is known as epigenetic modification in genomic DNA, was developed. The reaction was completely finished within 5 s of 366 nm irradiation, and the rate of this photocrosslinking reaction was ca. 30-fold higher than that in the case of unmodified normal cytosine. There were no significant differences in the thermodynamic parameters and the kinetics of hybrid formation of oligonucleotide (ODN) containing CNVK and its complementary ODN containing C or mC at the photocrosslinking site, and suggesting that the quick and selective photoreaction has potential for the selective detection of mC in the DNA strand via the photocrosslinking reaction. |
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