Games |
- CoGe VJ 1.4.3 - VJ application for real-time mixing. (Shareware)
- xPro 1.0 - Professional networking exclusively for Mac users. ()
- Apoc Wars - Screenshots
- Covenant of Solitude - Screenshots
- BattleDawn Galaxies
- Vitamin-R 2.0 - Personal productivity tool. (Shareware)
- Bridgy Jones - Screenshots
- Incredible Jack - Screenshots
- Antibiotics, Vol. 2, Pages 316-327: Prescriber and Patient Responsibilities in Treatment of Acute Respiratory Tract Infections — Essential for Conservation of Antibiotics
- IJERPH, Vol. 10, Pages 2282-2295: Knowledge, Attitude and Practices (KAP) Survey on Water, Sanitation and Hygiene in Selected Schools in Vhembe District, Limpopo, South Africa
- IJERPH, Vol. 10, Pages 2271-2281: Levels of Pesticides and Their Metabolites in Wistar Rat Amniotic Fluids and Maternal Urine upon Gestational Exposure
- Sensors, Vol. 13, Pages 7345-7384: Optoacoustic Imaging and Tomography: Reconstruction Approaches and Outstanding Challenges in Image Performance and Quantification
- Remote Sensing, Vol. 5, Pages 2838-2856: The Performance of Random Forests in an Operational Setting for Large Area Sclerophyll Forest Classification
- Sensors, Vol. 13, Pages 7323-7344: TREFEX: Trend Estimation and Change Detection in the Response of MOX Gas Sensors
- Molecules, Vol. 18, Pages 6584-6596: Indomethacin Inhibits Cancer Cell Migration via Attenuation of Cellular Calcium Mobilization
- Molecules, Vol. 18, Pages 6573-6583: New Lignans from the Leaves and Stems of Kadsura philippinensis
- Molecules, Vol. 18, Pages 6550-6572: One-Step Biofunctionalization of Quantum Dots with Chitosan and N-palmitoyl Chitosan for Potential Biomedical Applications
- Quell Memento - Screenshots
- Nutrients, Vol. 5, Pages 1970-1988: Peculiarities of Enhancing Resistant Starch in Ruminants Using Chemical Methods: Opportunities and Challenges
- IJGI, Vol. 2, Pages 507-530: Assessing Completeness and Spatial Error of Features in Volunteered Geographic Information
| CoGe VJ 1.4.3 - VJ application for real-time mixing. (Shareware) Posted: 04 Jun 2013 02:55 AM PDT  CoGe VJ is a semi-modular VJ application for OS X, designed for real-time media mixing and compositing, built over the most powerful graphics technologies like Quartz Composer, OpenGL, Syphon, and Core Image. The full rendering is done through the GPU of your graphics card for the maximum performance. CoGe has modular interface and modular ecosystem as well. Version 1.4.3:
OS X 10.6.7 or later More information |
| xPro 1.0 - Professional networking exclusively for Mac users. () Posted: 04 Jun 2013 02:45 AM PDT xPro networking is a professional social network built for Mac users. Before logging-in and using this app, you need to create a free account on our website. You can only create an account from a Mac computer. xPro networking allows you to connect and share opportunities, find the people and knowledge you need to achieve your goals. It's not about the most connections - it's about the right ones. xPro networking allows professionals and companies to connect, discover, and collaborate. It enables the Mac ecosystem to solve business problems and generate leads and opportunities by providing the right tools and services to collaborate in real time. Its mission is to connect Mac professionals, software, hardware, and service companies with end users, and to make them more productive and successful. xPro networking goes beyond internal collaboration to enable interaction with people outside the company, including experts, potential hires, and even customers. It differentiates itself in the world of social networking by focusing on the specific needs of Mac users. Our service will allow users to create professional profiles, and has various features that makes it possible for users to connect with other Mac professionals, companies, and products. Users will be able to post, connect, follow, share, rate, search and apply for jobs, etc. xPro networking hopes to become the most extensive, accurate, and accessible network focused on Mac users. OS X 10.6 or later More information |
| Posted: 04 Jun 2013 03:46 AM PDT Build and upgrade your base and its defenses to take on all comers. Ally with your friends and steal cool loot from enemy bases. Equip the loot you've acquired, from Frag Me Boots to the Sombrero of Glory, to boost your skills. Rid the wastelands of the rude and crude, attacking your rivals in real time with full control of your troops. Unlock new buildings and unique troops for inflicting maximum damage. And just because you can, blow lots of stuff up along the way! Key Features: o Build, defend and upgrade your awesome base. o Hundreds of items to collect and equip for unique tactical advantages. o Train a wide variety of combat units with special abilities: infantry, trucks, tanks, mechs, and more. o Spy on and attack enemy bases in real time, where you control the action. o Destroy your enemies and steal their loot. o Earn XP to upgrade existing forces and unlock new troops and buildings. o Create alliances with your friends and exact sweet revenge on your enemies! |
| Covenant of Solitude - Screenshots Posted: 04 Jun 2013 03:41 AM PDT Create characters freely By forging a contract with Fort, monsters will join his party. Create and advance these characters to fight with Fort. Combine tribe, gender, coloring and class freely to create a party that fits your own unique style. The four tribes are the Dragons, the Fairies, the Beasts and the Vampires. Each tribe and class has its own special qualities, giving you a wide range of possible characters. Boost abilities by changing classes Each of your characters can change classes, retaining the abilities from the previous class. For example, when you change your dragon, with its strength and attack capabilities, from the fighter class that emphasizes physical attacks to the wizard class and its powerful attack magic, your character will be a truly formidable foe in battle, with both physical and magical attacks. Or by advancing a vampire wizard with superb magical abilities, then switching to the healer class, you'll have a powerful magic user with access to both magical attack and healing skills. The biggest attraction of this game is the flexibility it brings to character building. Enjoy more with additional points (SP) By using additional points, you'll gain access to a variety of rare items which are useful in clearing the game's different stages. You'll even be able to enter special dungeons! |
| Posted: 04 Jun 2013 02:57 AM PDT Enter the world of Battle Dawn Galaxies a multiplayer online game set inside a massive galaxy with thousands of other real players from around the w.. |
| Vitamin-R 2.0 - Personal productivity tool. (Shareware) Posted: 04 Jun 2013 02:22 AM PDT  Vitamin-R creates the optimal conditions for your brain to work at its best by structuring your work into short bursts of distraction-free, highly focused activity alternating with opportunities for renewal, reflection and intuition. The built-in task logging and statistics features create a positive momentum towards productivity by providing visible feedback on your progress and achievements. Time Slice Your Work Get Started Find Your Rhythm Get It Out of Your Head Quickly Make It Your Own Now With Cloud Synching! Recapture the lost of art of joyful concentration. Overcome procrastination. Rediscover the motivation within yourself. Version 2.0:
More information |
| Posted: 04 Jun 2013 03:27 AM PDT Features - Over 32 levels to experiment with your own bridge designs - Drive Bridgy's train across your creations - Four different building materials: tracks, planks, ropes and concrete blocks - Great sense of humor—look out for great jokes in the loading screens. |
| Posted: 04 Jun 2013 03:21 AM PDT Classic platforming gameplay Incredible Jack harks back to the best of classic platformers; bounce on the heads of your enemies for points, use springs to propel Jack into the sky or to skim across water and take on seven mighty bosses. Journey through a magical world With 37 levels to explore, Jack will travel across treetops, through sand-filled tombs, icy caves and the overflowing lava pits of the underworld. Treasure everywhere Jack's children have left a trail of coins to help him track them down. Collect as many glittering treasures as you can by smashing over crates, barrels, sacks and in hidden areas. Game Features • A family fun platformer suitable for all ages • 37 levels spread across seven unique worlds • Fill your boots with coins from anything you can smash open • Use power-ups to fly or turn Jack into a coin magnet • UNIVERSAL; looks great on iPhone, iPod Touch and iPad |
| Posted: 04 Jun 2013 12:00 AM PDT Inappropriate antibiotic use in normally self-limiting acute respiratory tract infections (RTIs), such as sore throat and the common cold, is a global problem and an important factor for increasing levels of antibiotic resistance. A new group of international experts—the Global Respiratory Infection Partnership (GRIP)—is committed to addressing this issue, with the interface between primary care practitioners and their patients as their core focus. To combat the overuse of antibiotics in the community, and facilitate a change from prescribing empiric antibiotic treatment towards cautious deferment combined with symptomatic relief, there is a need to introduce and enhance evidence-based dialogue between primary care practitioners and their patients. Communication with patients should focus on the de-medicalisation of self-limiting viral infections, which can be achieved via a coherent globally endorsed framework outlining the rationale for appropriate antibiotic use in acute RTIs in the context of antibiotic stewardship and conservancy. The planned framework is intended to be adaptable at a country level to reflect local behaviours, cultures and healthcare systems, and has the potential to serve as a model for change in other therapeutic areas. |
| Posted: 04 Jun 2013 12:00 AM PDT This study assessed the knowledge, attitude and practices (KAP) of learners on issues related to water, sanitation and hygiene in selected schools in Vhembe District, South Africa. The methodology relied on a questionnaire, an inspection of sanitary facilities and discussion with the school authorities. The data was analyzed using the Statistical Package for Social Science. The study revealed that the level of knowledge about waterborne diseases was relatively high (76.7 ± 1.75%), but knowledge on transmission routes was inadequate. The majority of the respondents had no knowledge when it comes to water-based diseases and their prevention (78.4 ± 1.71%).The attitude and practice on hygiene was also found to be high (91.40 ± 1.16%). Some schools from the urban area had proper handwashing facilities, but there was no soap available. The borehole water quality for rural schools appeared clear, but the microbial quality was unknown. The water supply and sanitation facilities were inadequate in rural schools, with no handwashing areas and no sanitary bins for girls. Some schools had toilets with broken doors which did not offer privacy. The only water tap, located at the centre of the school premises, was not enough for the whole school community. |
| Posted: 04 Jun 2013 12:00 AM PDT Concentrations of pesticides and selected metabolites in rat urine and amniotic fluid were determined as biomarker upon oral administration of Wistar rats to two pesticide mixtures consisting of three to five pesticides (bitertanol, propiconazole, cypermethrin, malathion, and terbuthylazine). The pesticides and their metabolites were found in rat amniotic fluid and urine, generally in dose-response concentrations in relation to dosage. The measurement of the substances in the amniotic fluid indicated that the fetus was exposed to the pesticides as well as their metabolites. Moreover, the pesticides detected in urine demonstrated the exposure as well as the ability of the rat to excrete these compounds. |
| Posted: 04 Jun 2013 12:00 AM PDT This paper comprehensively reviews the emerging topic of optoacoustic imaging from the image reconstruction and quantification perspective. Optoacoustic imaging combines highly attractive features, including rich contrast and high versatility in sensing diverse biological targets, excellent spatial resolution not compromised by light scattering, and relatively low cost of implementation. Yet, living objects present a complex target for optoacoustic imaging due to the presence of a highly heterogeneous tissue background in the form of strong spatial variations of scattering and absorption. Extracting quantified information on the actual distribution of tissue chromophores and other biomarkers constitutes therefore a challenging problem. Image quantification is further compromised by some frequently-used approximated inversion formulae. In this review, the currently available optoacoustic image reconstruction and quantification approaches are assessed, including back-projection and model-based inversion algorithms, sparse signal representation, wavelet-based approaches, methods for reduction of acoustic artifacts as well as multi-spectral methods for visualization of tissue bio-markers. Applicability of the different methodologies is further analyzed in the context of real-life performance in small animal and clinical in-vivo imaging scenarios. |
| Posted: 04 Jun 2013 12:00 AM PDT Mapping and monitoring forest extent is a common requirement of regional forest inventories and public land natural resource management, including in Australia. The state of Victoria, Australia, has approximately 7.2 million hectares of mostly forested public land, comprising ecosystems that present a diverse range of forest structures, composition and condition. In this paper, we evaluate the performance of the Random Forest (RF) classifier, an ensemble learning algorithm that has recently shown promise using multi-spectral satellite sensor imagery for large area feature classification. The RF algorithm was applied using selected Landsat Thematic Mapper (TM) imagery metrics and auxiliary terrain and climatic variables, while the reference data was manually extracted from systematically distributed plots of sample aerial photography and used for training (75%) and accuracy (25%) assessment. The RF algorithm yielded an overall accuracy of 96% and a Kappa statistic of 0.91 (confidence interval (CI) 0.909–0.919) for the forest/non-forest classification model, given a Kappa maximised binary threshold value of 0.5. The area under the receiver operating characteristic plot produced a score of 0.91, also indicating high model performance. The framework described in this study contributes to the operational deployment of a robust, but affordable, program, able to collate and process large volumes of multi-sourced data using open-source software for the production of consistent and accurate forest cover maps across the full spectrum of Victorian sclerophyll forest types. |
| Posted: 04 Jun 2013 12:00 AM PDT Many applications of metal oxide gas sensors can benefit from reliable algorithms to detect significant changes in the sensor response. Significant changes indicate a change in the emission modality of a distant gas source and occur due to a sudden change of concentration or exposure to a different compound. As a consequence of turbulent gas transport and the relatively slow response and recovery times of metal oxide sensors, their response in open sampling configuration exhibits strong fluctuations that interfere with the changes of interest. In this paper we introduce TREFEX, a novel change point detection algorithm, especially designed for metal oxide gas sensors in an open sampling system. TREFEX models the response of MOX sensors as a piecewise exponential signal and considers the junctions between consecutive exponentials as change points. We formulate non-linear trend filtering and change point detection as a parameter-free convex optimization problem for single sensors and sensor arrays. We evaluate the performance of the TREFEX algorithm experimentally for different metal oxide sensors and several gas emission profiles. A comparison with the previously proposed GLR method shows a clearly superior performance of the TREFEX algorithm both in detection performance and in estimating the change time. |
| Posted: 04 Jun 2013 12:00 AM PDT Non-steroidal anti-inflammatory drugs (NSAIDs) were shown to reduce the risk of colorectal cancer recurrence and are widely used to modulate inflammatory responses. Indomethacin is an NSAID. Herein, we reported that indomethacin can suppress cancer cell migration through its influence on the focal complexes formation. Furthermore, endothelial growth factor (EGF)-mediated Ca2+ influx was attenuated by indomethacin in a dose dependent manner. Our results identified a new mechanism of action for indomethacin: inhibition of calcium influx that is a key determinant of cancer cell migration. |
| Molecules, Vol. 18, Pages 6573-6583: New Lignans from the Leaves and Stems of Kadsura philippinensis Posted: 04 Jun 2013 12:00 AM PDT Three novel C19 homolignans, taiwankadsurins D (1), E (2) and F (4), and two new C18 lignans kadsuphilins N (3) and O (5) were isolated from the aerial parts of Taiwanese medicinal plant Kadsura philippinensis. The structures of compounds 1–5 were determined by spectroscopic analyses, especially 2D NMR techniques. The structure of compound 5 was further confirmed by X-ray crystallographic analysis. Compounds 1 and 2 have a 3,4-{1'-[(Z)-2''-methoxy-2''-oxoethylidene]}-pentano(2,3-dihydrobenzo[b]furano)-3-(2'''-methoxycarbonyl-2'''-hydroxy-2''',3'-epoxide) skeleton. |
| Posted: 04 Jun 2013 12:00 AM PDT Carbohydrates and derivatives (such as glycolipids, glycoproteins) are of critical importance for cell structure, metabolism and functions. The effects of carbohydrate and lipid metabolic imbalances most often cause health disorders and diseases. In this study, new carbohydrate-based nanobioconjugates were designed and synthesized at room temperature using a single-step aqueous route combining chitosan and acyl-modified chitosan with fluorescent inorganic nanoparticles. N-palmitoyl chitosan (C-Pal) was prepared aiming at altering the lipophilic behavior of chitosan (CHI), but also retaining its reasonable water solubility for potential biomedical applications. CHI and C-Pal were used for producing biofunctionalized CdS quantum dots (QDs) as colloidal water dispersions. Fourier transform infrared spectroscopy (FTIR), thermal analysis (TG/DSC), surface contact angle (SCA), and degree of swelling (DS) in phosphate buffer were used to characterize the carbohydrates. Additionally, UV-Visible spectroscopy (UV-Vis), photoluminescence spectroscopy (PL), dynamic light scattering (DLS), scanning and transmission electron microscopy (SEM/TEM) were used to evaluate the precursors and nanobioconjugates produced. The FTIR spectra associated with the thermal analysis results have undoubtedly indicated the presence of N-palmitoyl groups "grafted" to the chitosan chain (C-Pal) which significantly altered its behavior towards water swelling and surface contact angle as compared to the unmodified chitosan. Furthermore, the results have evidenced that both CHI and C-Pal performed as capping ligands on nucleating and stabilizing colloidal CdS QDs with estimated average size below 3.5 nm and fluorescent activity in the visible range of the spectra. Therefore, an innovative "one-step" process was developed via room temperature aqueous colloidal chemistry for producing biofunctionalized quantum dots using water soluble carbohydrates tailored with amphiphilic behavior offering potential applications as fluorescent biomarkers in the investigation of glycoconjugates for the nutrition, biology, pharmaceutical, and medicine fields. |
| Posted: 04 Jun 2013 02:47 AM PDT Quell Memento is an enchanting puzzle-game mixing logic and a beautifully relaxing ambiance. With more than 160 levels of ingenious level design, it's sure to appeal to puzzle fans. Features: - More than 10 hours of gameplay - 9 chapters containing 144 different levels (and more than 20 bonus puzzles) - A relaxing soundtrack with an audio voice-over and subtitles - 30 achievements to complete - iCloud Support - Full HD / Retina support - Universal App |
| Posted: 04 Jun 2013 12:00 AM PDT High-producing ruminants are fed high amounts of cereal grains, at the expense of dietary fiber, to meet their high energy demands. Grains consist mainly of starch, which is easily degraded in the rumen by microbial glycosidases, providing energy for rapid growth of rumen microbes and short-chain fatty acids (SCFA) as the main energy source for the host. Yet, low dietary fiber contents and the rapid accumulation of SCFA lead to rumen disorders in cattle. The chemical processing of grains has become increasingly important to confer their starch resistances against rumen microbial glycosidases, hence generating ruminally resistant starch (RRS). In ruminants, unlike monogastric species, the strategy of enhancing resistant starch is useful, not only in lowering the amount of carbohydrate substrates available for digestion in the upper gut sections, but also in enhancing the net hepatic glucose supply, which can be utilized by the host more efficiently than the hepatic gluconeogenesis of SCFA. The use of chemical methods to enhance the RRS of grains and the feeding of RRS face challenges in the practice; therefore, the present article attempts to summarize the most important achievements in the chemical processing methods used to generate RRS, and review advantages and challenges of feeding RRS to ruminants |
| Posted: 04 Jun 2013 12:00 AM PDT The assessment of the quality and accuracy of Volunteered Geographic Information (VGI) contributions, and by extension the ultimate utility of VGI data has fostered much debate within the geographic community. The limited research to date has been focused on VGI data of linear features and has shown that the error in the data is heterogeneously distributed. Some have argued that data produced by numerous contributors will produce a more accurate product than an individual and some research on crowd-sourced initiatives has shown that to be true, although research on VGI is more infrequent. This paper proposes a method for quantifying the completeness and accuracy of a select subset of infrastructure-associated point datasets of volunteered geographic data within a major metropolitan area using a national geospatial dataset as the reference benchmark with two datasets from volunteers used as test datasets. The results of this study illustrate the benefits of including quality control in the collection process for volunteered data. |
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