Games |
- Spyder 2.2.5 - MySpace social network browser.. (Shareware)
- Path of Exile - PC - Screenshots
- Groove Coaster - iPhone - Screenshots
- IJMS, Vol. 12, Pages 4923-4945: The Langmuir-Blodgett Technique as a Tool for Homeotropic Alignment of Fluorinated Liquid Crystals Mixed with Arachidic Acid
- IJMS, Vol. 12, Pages 4909-4922: Experimental and Theoretical Electron Paramagnetic Resonance (EPR) Study on the Temperature-Dependent Structural Changes of Methylsulfanylmethane
- IJMS, Vol. 12, Pages 4896-4908: In Vitro and in Vivo Antioxidant Properties of the Plant-Based Supplement Greens+TM
- Molecules, Vol. 16, Pages 6502-6511: 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives
- Molecules, Vol. 16, Pages 6489-6501: Inhibitory Effect and Possible Mechanism of Action of Patchouli Alcohol against Influenza A (H2N2) Virus
- Molecules, Vol. 16, Pages 6481-6488: Phenylacetonitrile from the Giant Knotweed, Fallopia sachalinensis, Infested by the Japanese Beetle, Popillia japonica, Is Induced by Exogenous Methyl Jasmonate
- King's Bounty: Legions - Mac - Screenshots
- King's Bounty: Legions - PC - Screenshots
- NetUse Traffic Monitor 1.2.1 - Monitor your network traffic.. (Commercial)
- TrailRunner 3.6.645 - Route planning for hiking, biking, more.. (Shareware)
- 1Password 3.7.1 - Powerful password manager; integrates with Web browsers and more.. (Shareware)
- MarsEdit 3.3.2 - Weblog editor.. (Shareware)
- Google Chrome 13.0.782.107 - Modern and fast Web browser.. (Free)
- Powerball Winning Numbers for 07/30/2011
- Powerball Estimated Jackpot for 08/03/2011
- Mega Millions Winning Numbers for 08/02/2011
- Mega Millions Estimated Jackpot for 08/05/2011
| Spyder 2.2.5 - MySpace social network browser.. (Shareware) Posted: 03 Aug 2011 03:07 AM PDT  Spyder is a social network browser for MySpace that makes it easy to organize, browse, comment, message, and make new friends. Spyder also comes with a song/video play increaser and CAPTCHA bypass. Spyder makes it easy to keep in touch with your friends or fan-base by message or comment. Add as many friends as you want, Spyder allows you to send friend requests too. Spyder also helps you manage all your accounts, whether you have just a personal account or an additional band or business account you can easily switch between your different accounts in Spyder. And for people that remember faces better than names Spyder downloads users pictures automatically. Version 2.2.5:
Mac OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Path of Exile - PC - Screenshots Posted: 03 Aug 2011 02:54 AM PDT AUCKLAND, New Zealand – September 1, 2010 – Independent games studio Grinding Gear Games today announced Path of Exile, a free-to-play PC online action Role-Playing Game (RPG) set in a dark fantasy world. The game will be available in early 2011. Playing as one of six character classes, players find themselves banished for their past misdeeds to the dark fantasy world of Wraeclast. There, they will encounter hundreds of species of opponents laden with loot and mysterious artefacts as they explore the abandoned continent. Players will be able to purchase in-game perks, such as extra victory animations, clothing and special effects. To protect the integrity of the game for all players, Grinding Gear Games has decided not to sell abilities or experience points – ensuring a level-playing field for everyone in game. "We listened to the fan communities of several popular online action RPGs as we designed Path of Exile and are focused on replayability, depth and accessibility," said Chris Wilson, Grinding Gear Games' Founder. "We've designed the game that we would want to play ourselves, and we know hardcore Diablo, Titan Quest and Dungeon Siege players will find the style familiar and addictive." Wilson believes there has been a shortage of dark fantasy worlds in recent RPGs. "While the art style is a return to the classic dark fantasy that many hardcore players grew up with, we're confident the difficulty curve is accessible enough for anyone. There are no rainbows and unicorns in our game, but there is plenty of blood and rare items to collect." With an open-ended and flexible skill and item system, randomised items and random dungeons, the game promises three acts of visceral combat gameplay, with additional ... |
| Groove Coaster - iPhone - Screenshots Posted: 03 Aug 2011 02:54 AM PDT Create an original stage that grows and changes according to your progress through the game! Impress your friends! The music included covers a wide spectrum, from rock and pop to hip-hop and techno! Don't just listen to music, game with it! |
| Posted: 03 Aug 2011 12:00 AM PDT Some fluoro-substituted liquid crystals mixed with arachidic acid in monolayers formed at air-liquid (Langmuir films) and air-solid substrate (Langmuir-Blodgett films) interfaces were investigated. Molecular organization in Langmuir films was determined on the basis of the analysis of the shape of the surface pressure-mean molecular area isotherm and observations made by means of a Brewster angle microscope. It was found that in the compression process the liquid crystal molecules are pushed out towards the top of the first monolayer being in direct contact with the subphase. Langmuir films were transferred onto the quartz substrates at various surface pressures and mono- and multilayered Langmuir-Blodgett films were obtained. The films were characterized using electronic absorption measurements. The conditions for obtaining the homeotropic orientation of the liquid crystal molecules were determined. |
| Posted: 03 Aug 2011 12:00 AM PDT Methylsulfonylmethane (or dimethyl sulfone), a naturally produced and vitally important organosulfur compound in living organisms, was irradiated with gamma rays, and the produced radicals were investigated using electron paramagnetic resonance spectroscopy at different temperatures. The structure and behavior of the radical changed when the temperatures varied. The hyperfine splitting of the CH3 group was small, and the 33S splitting was relatively high between 80 and −50 °C. When the temperature was between −50 and −160 °C, the 33S splitting became small and the CH3 splitting was higher. However, the group kept rotating; therefore, only the isotropic splitting values were measured, and the g-values were anisotropic. When the temperature decreased below −180 °C, the CH3 group stopped rotating, and the hydrogen splitting values became nonequivalent due to an inhomogeneous electron distribution. The observed structures can be explained by referring to both the experimental and theoretically calculated values reported. |
| Posted: 03 Aug 2011 12:00 AM PDT Dietary antioxidants play an important role against oxidation, an underlying mechanism in the incidence of chronic diseases. Greens+ is a commercially available preparation containing a variety of plant-derived ingredients. The aim of the current study was to evaluate the antioxidant potential of the methanolic extract of greens+ powder using in vitro and in vivo techniques. In vitro studies were conducted using a liposome model system to simulate biological cell membranes. Total antioxidant potential and polyphenol content of the herbal preparation was measured. For in vivo analysis, 10 healthy human subjects consumed either three or six teaspoons of greens+ per day for four weeks. Blood samples were analyzed at baseline and at the conclusion of the treatment period for total antioxidant capacity, polyphenol content, protein, lipid and LDL oxidation, and the level of glutathione peroxidase. Results showed that greens+ supplementation was well tolerated and increased serum antioxidant potential at higher levels of intake in a dose-dependent manner. HPLC analysis showed the presence of quercetin, apigenin, kaempferol and luteolin in the supplement. Plasma analysis indicated the presence of kaempferol only. A statistically significant (p < 0.05) reduction in protein and lipid oxidation was observed. Based on its antioxidant properties, the results suggest that greens+ might play a role in reducing the risk of chronic diseases involving a burden of oxidative damage. |
| Posted: 03 Aug 2011 12:00 AM PDT A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivatives with appropriate N-nucleophiles afforded the target compounds. All compounds were characterized by 1H-, 13C-NMR, GCMS, IR, and UV-Vis spectrometry. These compounds represent a new class of sulfur- and nitrogen-containing heterocycles that should also be of interest as new materials. |
| Posted: 03 Aug 2011 12:00 AM PDT In the present study, the anti-influenza A (H2N2) virus activity of patchouli alcohol was studied in vitro, in vivo and in silico. The CC50 of patchouli alcohol was above 20 µM. Patchouli alcohol could inhibit influenza virus with an IC50 of 4.03 ± 0.23 µM. MTT assay showed that the inhibition by patchouli alcohol appears strongly after penetration of the virus into the cell. In the influenza mouse model, patchouli alcohol showed obvious protection against the viral infection at a dose of 5 mg/kg/day. Flexible docking and molecular dynamic simulations indicated that patchouli alcohol was bound to the neuraminidase protein of influenza virus, with an interaction energy of –40.38 kcal mol–1. The invariant key active-site residues Asp151, Arg152, Glu119, Glu276 and Tyr406 played important roles during the binding process. Based on spatial and energetic criteria, patchouli alcohol interfered with the NA functions. Results presented here suggest that patchouli alcohol possesses anti-influenza A (H2N2) virus properties, and therefore is a potential source of anti-influenza agents for the pharmaceutical industry. |
| Posted: 03 Aug 2011 12:00 AM PDT Phenylacetonitrile, (E)-b-ocimene, linalool, (E)-4,8-dimethyl-1,3,7-nonatriene and (E,E)-a-farnesene were identified as Japanese beetle, Popillia japonica, feeding-induced volatiles from the leaves of the giant knotweed, Fallopia sachalinensis, but not by mechanical damage. Volatile emission was also induced by treatment with a cellular signaling molecule, methyl jasmonate. These results suggest that volatiles will be synthesized de novo by a biotic elicitor from P. japonica oral secretion. |
| King's Bounty: Legions - Mac - Screenshots Posted: 03 Aug 2011 01:53 AM PDT Gamers who strategically assemble a well-balanced army and exploit different advantages held by some classes over others, will enjoy more success and potentially achieve a higher Legion ranking in PvP. Classes include the following: - Archer - This range class offers players the chance to deal damage while keeping a safe distance from the fray. - Defender - The best offense is a good defense, as demonstrated with their ability to withstand heavy attacks from enemies. - Mage - Unleash magical powers to conquer foes from afar with these masters of the mystic arts. - Support - Everybody needs somebody to watch their back and this class is the go-to back-up in battle. - Warrior - Whether it's swinging a big sword, showing off some big fangs or just being a frontline trooper, this class will get up close and personal with foes. King's Bounty: Legions will be a cross-platform title, appearing initially on Facebook, and later on iOS and Android platforms for mobile and tablet devices. The game is being developed on the Unity 3D engine, allowing for the popular King's Bounty art style to help raise the visual quality expectations of browser-based, social games. |
| King's Bounty: Legions - PC - Screenshots Posted: 03 Aug 2011 01:53 AM PDT Gamers who strategically assemble a well-balanced army and exploit different advantages held by some classes over others, will enjoy more success and potentially achieve a higher Legion ranking in PvP. Classes include the following: - Archer - This range class offers players the chance to deal damage while keeping a safe distance from the fray. - Defender - The best offense is a good defense, as demonstrated with their ability to withstand heavy attacks from enemies. - Mage - Unleash magical powers to conquer foes from afar with these masters of the mystic arts. - Support - Everybody needs somebody to watch their back and this class is the go-to back-up in battle. - Warrior - Whether it's swinging a big sword, showing off some big fangs or just being a frontline trooper, this class will get up close and personal with foes. King's Bounty: Legions will be a cross-platform title, appearing initially on Facebook, and later on iOS and Android platforms for mobile and tablet devices. The game is being developed on the Unity 3D engine, allowing for the popular King's Bounty art style to help raise the visual quality expectations of browser-based, social games. |
| NetUse Traffic Monitor 1.2.1 - Monitor your network traffic.. (Commercial) Posted: 03 Aug 2011 12:31 AM PDT  NetUse Traffic Monitor provides the best way to monitor your network traffic on the Mac. Utilizing the SNMP feature of any modern Internet router or gateway, NetUse monitors and collects real-time Internet usage statistics for all the computers in your home or office that share an Internet connection. If you have a traffic cap on your Internet usage, NetUse will help make sure you don't exceed your limits. Set your billing date and a monthly traffic allowance and NetUse will accurately show how much bandwidth you consume. Features:
NetUse requires the SNMP feature on your router or gateway to be enabled. Please check your hardware specifications to ensure that it supports SNMP before trying NetUse. Or download our free SNMP test utility.
Mac OS X 10.6.6 or later Download Now |
| TrailRunner 3.6.645 - Route planning for hiking, biking, more.. (Shareware) Posted: 02 Aug 2011 08:59 PM PDT  TrailRunner is the perfect companion for runners, bikers, hikers, and all people wandering under the sky. Plan routes on a geographical map. Import GPS or workout recordings and journalize your activities in a diary. Features:
Version 3.6.645:
Mac OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| 1Password 3.7.1 - Powerful password manager; integrates with Web browsers and more.. (Shareware) Posted: 02 Aug 2011 08:59 PM PDT  1Password is a password manager that uniquely brings you both security and convenience. It is the only program that provides anti-phishing protection and goes beyond password management by adding web form filling and automatic strong password generation. All your confidential information, including passwords, identities, and credit cards, is kept secure in one secure place using a highly encrypted keychain. 1Password fully supports most web browsers, including Safari, OmniWeb, DEVONagent, Firefox, Flock, Fluid, and NetNewsWire. All browser extensions share the data stored in the keychain which means you never need to manually copy your passwords between browsers or from the password manager to a browser ever again! 1Password has received numerous awards, including 4.5 mice from Macworld magazine, MacLife Editors pick, and was the Pick of Week on MacBreak Weekly by both Leo Laporte and Merlin Mann. 1Password also has a companion iPhone/iPod touch application available in iTunes App Store. Version 3.7.1:
Download Now This posting includes an audio/video/photo media file: Download Now |
| MarsEdit 3.3.2 - Weblog editor.. (Shareware) Posted: 02 Aug 2011 08:59 PM PDT  MarsEdit is a blog editor for Mac OS X that makes editing your blog like writing email, with spell-checking, drafts, multiple windows, and even AppleScript support. It works with with most blog services including WordPress, Blogger, Drupal, Movable Type, TypePad, and many others. Version 3.3.2:
Mac OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Google Chrome 13.0.782.107 - Modern and fast Web browser.. (Free) Posted: 02 Aug 2011 08:59 PM PDT  Google Chrome is a Web browser by Google, created to be a modern platform for web pages and applications. It utilizes very fast loading of web pages and has a V8 engine, which is a custom built JavaScript engine. Because Google has used parts from Apple's Safari and Firefox browsers, they made the project open source. Version 13.0.782.107:
Mac OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Powerball Winning Numbers for 07/30/2011 Posted: 02 Aug 2011 10:34 PM PDT 20 - 40 - 41 - 47 - 55 Powerball 19 Power Play 2 |
| Powerball Estimated Jackpot for 08/03/2011 Posted: 02 Aug 2011 10:34 PM PDT Annuitized: $160 Million Cash Value: $85.2 Million |
| Mega Millions Winning Numbers for 08/02/2011 Posted: 02 Aug 2011 10:34 PM PDT 14 - 17 - 19 - 20 - 32 MegaBall 28 Megaplier 4 |
| Mega Millions Estimated Jackpot for 08/05/2011 Posted: 02 Aug 2011 10:34 PM PDT Annuitized: $99 Million Cash Value: $66.0 Million |
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