Games |
- More Free Bingo Games Available On The New Bingo Liner UK Site
- UPS Logger 1.5.0 - Adds basic logging to existing UPS support in OS X.. (Free)
- Radio Silence 1.01 - Outbound application firewall.. (Commercial)
- iCal Dupe Deleter 1.2.2 - Aids removal of duplicate timed events in iCal.. (Shareware)
- Sensors, Vol. 11, Pages 8430-8455: A Novel Addressing Scheme for PMIPv6 Based Global IP-WSNs
- Sensors, Vol. 11, Pages 8412-8429: A Novel Method to Increase LinLog CMOS Sensors’ Performance in High Dynamic Range Scenarios
- Sensors, Vol. 11, Pages 8395-8411: Development of an Integrated Microfluidic Perfusion Cell Culture System for Real-Time Microscopic Observation of Biological Cells
- Insects, Vol. 2, Pages 412-422: Temperature and Time Requirements for Controlling Bed Bugs (Cimex lectularius) under Commercial Heat Treatment Conditions
- Materials, Vol. 4, Pages 1519-1527: Spinning Carbon Nanotube Nanothread under a Scanning Electron Microscope
- Sensors, Vol. 11, Pages 8370-8394: Ontological Problem-Solving Framework for Assigning Sensor Systems and Algorithms to High-Level Missions
- Entropy, Vol. 13, Pages 1584-1594: Local Stability Analysis of a Thermo-Economic Model of a Chambadal-Novikov-Curzon-Ahlborn Heat Engine
- Sensors, Vol. 11, Pages 8358-8369: A Fusion-Spliced Near-Field Optical Fiber Probe Using Photonic Crystal Fiber for Nanoscale Thermometry Based on Fluorescence-Lifetime Measurement of Quantum Dots
- Sensors, Vol. 11, Pages 8339-8357: Odometry and Laser Scanner Fusion Based on a Discrete Extended Kalman Filter for Robotic Platooning Guidance
- Energies, Vol. 4, Pages 1301-1320: Classification of Fundamental Ferroresonance, Single Phase-to-Ground and Wire Breakage Over-Voltages in Isolated Neutral Networks
- Energies, Vol. 4, Pages 1278-1300: An S-Transform and Support Vector Machine (SVM)-Based Online Method for Diagnosing Broken Strands in Transmission Lines
- Polymers, Vol. 3, Pages 1433-1446: Microscopic and Spectroscopic Investigation of Poly(3-hexylthiophene) Interaction with Carbon Nanotubes
- Polymers, Vol. 3, Pages 1423-1432: Consolidation of Inorganic Precipitated Silica Gel
- Pharmaceutics, Vol. 3, Pages 572-581: Development and Validation of a Microbiological Agar Assay for Determination of Orbifloxacin in Pharmaceutical Preparations
- Molecules, Vol. 16, Pages 7357-7364: Antibacterial Activity of Aristolochia brevipes against Multidrug-Resistant Mycobacterium tuberculosis
- Molecules, Vol. 16, Pages 7344-7356: Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay
| More Free Bingo Games Available On The New Bingo Liner UK Site Posted: 29 Aug 2011 03:15 AM PDT Bingo Liner is gearing up for a new look and feel to the UK site, so find out what offers and the array of bingo games that will be available. |
| UPS Logger 1.5.0 - Adds basic logging to existing UPS support in OS X.. (Free) Posted: 29 Aug 2011 03:14 AM PDT UPS Logger is a Startup Item that adds basic log messages to the existing support for a UPS (Uninterruptible Power Supply) support built-in to the Mac OS X Energy Saver Preference Pane. It does not affect in any way the operation of your UPS, or Energy Saver. The log file that UPS Logger creates will be at /Library/Logs/UPS Logger.log. It can be easily viewed in the Console application, as it shows up very conveniently in the "Logs" list. Version 1.5.0 :
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| Radio Silence 1.01 - Outbound application firewall.. (Commercial) Posted: 29 Aug 2011 03:08 AM PDT  Radio Silence is an outbound application firewall that lets you block internet access from individual apps. 100% Annoyance-free:
Version 1.01:
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| iCal Dupe Deleter 1.2.2 - Aids removal of duplicate timed events in iCal.. (Shareware) Posted: 29 Aug 2011 03:15 AM PDT  iCal Dupe Deleter is a straight-forward application to aid the removal of duplicate events and todos in iCal. It allows the selection of individual calendars for testing, shows the number of duplicates found and displays the progress of deletions. This application is donationware. If you find it useful please make a small donation to the developer. Version 1.2.2:
Download Now This posting includes an audio/video/photo media file: Download Now |
| Sensors, Vol. 11, Pages 8430-8455: A Novel Addressing Scheme for PMIPv6 Based Global IP-WSNs Posted: 29 Aug 2011 12:00 AM PDT IP based Wireless Sensor Networks (IP-WSNs) are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper. |
| Posted: 29 Aug 2011 12:00 AM PDT Images from high dynamic range (HDR) scenes must be obtained with minimum loss of information. For this purpose it is necessary to take full advantage of the quantification levels provided by the CCD/CMOS image sensor. LinLog CMOS sensors satisfy the above demand by offering an adjustable response curve that combines linear and logarithmic responses. This paper presents a novel method to quickly adjust the parameters that control the response curve of a LinLog CMOS image sensor. We propose to use an Adaptive Proportional-Integral-Derivative controller to adjust the exposure time of the sensor, together with control algorithms based on the saturation level and the entropy of the images. With this method the sensor's maximum dynamic range (120 dB) can be used to acquire good quality images from HDR scenes with fast, automatic adaptation to scene conditions. Adaptation to a new scene is rapid, with a sensor response adjustment of less than eight frames when working in real time video mode. At least 67% of the scene entropy can be retained with this method. |
| Posted: 29 Aug 2011 12:00 AM PDT This study reports an integrated microfluidic perfusion cell culture system consisting of a microfluidic cell culture chip, and an indium tin oxide (ITO) glass-based microheater chip for micro-scale perfusion cell culture, and its real-time microscopic observation. The system features in maintaining both uniform, and stable chemical or thermal environments, and providing a backflow-free medium pumping, and a precise thermal control functions. In this work, the performance of the medium pumping scheme, and the ITO glass microheater were experimentally evaluated. Results show that the medium delivery mechanism was able to provide pumping rates ranging from 15.4 to 120.0 μL·min−1. In addition, numerical simulation and experimental evaluation were conducted to verify that the ITO glass microheater was capable of providing a spatially uniform thermal environment, and precise temperature control with a mild variation of ±0.3 °C. Furthermore, a perfusion cell culture was successfully demonstrated, showing the cultured cells were kept at high cell viability of 95 ± 2%. In the process, the cultured chondrocytes can be clearly visualized microscopically. As a whole, the proposed cell culture system has paved an alternative route to carry out real-time microscopic observation of biological cells in a simple, user-friendly, and low cost manner. |
| Posted: 29 Aug 2011 12:00 AM PDT Developing effective alternative approaches for disinfesting bed bugs from residential spaces requires a balance between obtaining complete insect mortality, while minimizing costs and energy consumption. One method of disinfestation is the application of lethal high temperatures directly to rooms and contents within a structure (termed whole-room heat treatments). However, temperature and time parameters for efficacy in whole-room heat treatments are unknown given the slower rate of temperature increase and the probable variability of end-point temperatures within a treated room. The objective of these experiments was to explore requirements to produce maximum mortality from heat exposure using conditions that are more characteristic of whole-room heat treatments. Bed bugs were exposed in an acute lethal temperature (LTemp) trial, or time trials at sub-acute lethal temperatures (LTime). The lethal temperature (LTemp99) for adults was 48.3 °C, while LTemp99 for eggs was 54.8 °C. Adult bed bugs exposed to 45 °C had a LTime99 of 94.8 min, while eggs survived 7 h at 45 °C and only 71.5 min at 48 °C. We discuss differences in exposure methodologies, potential reasons why bed bugs can withstand higher temperatures and future directions for research. |
| Posted: 29 Aug 2011 12:00 AM PDT Nanothread with a diameter as small as one hundred nanometers was manufactured under a scanning electron microscope. Made directly from carbon nanotubes, and inheriting their superior electrical and mechanical properties, nanothread may be the world's smallest man-made fiber. The smallest thread that can be spun using a bench-top spinning machine is about 5 microns in diameter. Nanothread is a new material building block that can be used at the nanoscale or plied to form yarn for applications at the micro and macro scales. Preliminary electrical and mechanical properties of nanothread were measured. The resistivity of nanothread is less than 10−5 Ω∙m. The strength of nanothread is greater than 0.5 GPa. This strength was obtained from measurements using special glue that cures in an electron microscope. The glue weakened the thread, thus further work is needed to obtain more accurate measurements. Nanothread will have broad applications in enabling electrical components, circuits, sensors, and tiny machines. Yarn can be used for various macroscale applications including lightweight antennas, composites, and cables. |
| Posted: 29 Aug 2011 12:00 AM PDT The lack of knowledge models to represent sensor systems, algorithms, and missions makes opportunistically discovering a synthesis of systems and algorithms that can satisfy high-level mission specifications impractical. A novel ontological problem-solving framework has been designed that leverages knowledge models describing sensors, algorithms, and high-level missions to facilitate automated inference of assigning systems to subtasks that may satisfy a given mission specification. To demonstrate the efficacy of the ontological problem-solving architecture, a family of persistence surveillance sensor systems and algorithms has been instantiated in a prototype environment to demonstrate the assignment of systems to subtasks of high-level missions. |
| Posted: 29 Aug 2011 12:00 AM PDT In this work we present a local stability analysis of the thermo-economic model of an irreversible heat engine working at maximum power conditions. The thermo-economic model is based on the maximization of a benefit function which is defined by the ratio of the power output and the total cost involved in the plant's performance. Our study shows that, after a small perturbation, the system decays exponentially to the steady state determined by two different relaxation times. In particular, we show that the relaxation times are function of the temperature ratio τ = T2/T1 (T1 > T2), the cost function ƒ and the parameter R (a parameter related to the degree of internal irreversibilities). We observe that the stability of the system improves as τ increases whereas for changes in ƒ and R, the stability properties are characterized by a rapid decay along the fast eigendirection as ƒ increases and R decreases. Finally, we discuss our results in the context of energetic properties. |
| Posted: 29 Aug 2011 12:00 AM PDT We have developed a novel nanoscale temperature-measurement method using fluorescence in the near-field called Fluorescence Near-field Optics Thermal Nanoscopy (Fluor-NOTN). Fluor-NOTN enables the temperature distributions of nanoscale materials to be measured in vivo/in situ. The proposed method measures temperature by detecting the temperature dependent fluorescence lifetimes of Cd/Se Quantum Dots (QDs). For a high-sensitivity temperature measurement, the auto-fluorescence generated from a fiber probe should be reduced. In order to decrease the noise, we have fabricated a novel near-field optical-fiber probe by fusion-splicing a photonic crystal fiber (PCF) and a conventional single-mode fiber (SMF). The validity of the novel fiber probe was assessed experimentally by evaluating the auto-fluorescence spectra of the PCF. Due to the decrease of auto-fluorescence, a six- to ten-fold increase of S/N in the near-field fluorescence lifetime detection was achieved with the newly fabricated fusion-spliced near-field optical fiber probe. Additionally, the near-field fluorescence lifetime of the quantum dots was successfully measured by the fabricated fusion-spliced near-field optical fiber probe at room temperature, and was estimated to be 10.0 ns. |
| Posted: 29 Aug 2011 12:00 AM PDT This paper describes a relative localization system used to achieve the navigation of a convoy of robotic units in indoor environments. This positioning system is carried out fusing two sensorial sources: (a) an odometric system and (b) a laser scanner together with artificial landmarks located on top of the units. The laser source allows one to compensate the cumulative error inherent to dead-reckoning; whereas the odometry source provides less pose uncertainty in short trajectories. A discrete Extended Kalman Filter, customized for this application, is used in order to accomplish this aim under real time constraints. Different experimental results with a convoy of Pioneer P3-DX units tracking non-linear trajectories are shown. The paper shows that a simple setup based on low cost laser range systems and robot built-in odometry sensors is able to give a high degree of robustness and accuracy to the relative localization problem of convoy units for indoor applications. |
| Posted: 29 Aug 2011 12:00 AM PDT This paper proposes a simple and effective method for classification of fundamental ferroresonance, single phase-to-ground and wire breakage over-voltages. In isolated neutral networks, power frequency over-voltages due to ferroresonance, single phase-to-ground and wire breakage may exist for a long time, and have very highly similar voltage features. If the improper suppression operation is applied due to incorrect identification, the accident is likely to worsen further. In this paper, the voltage and current features of these faults are analyzed, and a new effective classification criterion for fundamental ferroresonance and single phase-to-ground based on zero sequence current is proposed. A comprehensive identification method based on voltage, current and zero sequence current features is proposed, which is feasible and promising for real applications. |
| Posted: 29 Aug 2011 12:00 AM PDT During their long-term outdoor field service, overhead transmission lines will be exposed to strikes by lightning, corrosion by chemical contaminants, ice-shedding, wind vibration of conductors, line galloping, external destructive forces and so on, which will generally cause a series of latent faults such as aluminum strand fracture. This may lead to broken transmission lines which will have a very strong impact on the safe operation of power grids that if the latent faults cannot be recognized and fixed as soon as possible. The detection of broken strands in transmission lines using inspection robots equipped with suitable detectors is a method with good prospects. In this paper, a method for detecting broken strands in transmission lines using an eddy current transducer (ECT) carried by a robot is developed, and an approach for identifying broken strands in transmission lines based on an S-transform is proposed. The proposed approach utilizes the S-transform to extract the module and phase information at each frequency point from detection signals. Through module phase and comparison, the characteristic frequency points are ascertained, and the fault information of the detection signal is constructed. The degree of confidence of broken strand identification is defined by the Shannon fuzzy entropy (SFE-BSICD). The proposed approach combines module information while utilizing phase information, SFE-BSICD, and the energy, so the reliability is greatly improved. These characteristic qualities of broken strands in transmission lines are used as the input of a multi-classification SVM, allowing the number of broken strands to be determined. Through experimental field verification, it can be shown that the proposed approach displays high accuracy and the SFE-BSICD is defined reasonably. |
| Posted: 29 Aug 2011 12:00 AM PDT The inclusion of carbon nanotubes in polymer matrix has been proposed to enhance the polymer's physical and electrical properties. In this study, microscopic and spectroscopic techniques are used to investigate the interaction between poly(3-hexylthiophene) (P3HT) and nanotubes and the reciprocal modification of physical properties. The presence of P3HT-covered nanotubes dispersed in the polymer matrix has been observed by atomic force microscopy and transmission electron microscopy. Then, the modification of P3HT optical properties due to nanotube inclusion has been evidenced with spectroscopic techniques like absorption and Raman spectroscopy. The study is completed with detailed nanoscale analysis by scanning probe techniques. The ordered self assembly of polymer adhering on the nanotube is unveiled by showing an example of helical wrapping of P3HT. Scanning tunneling spectroscopy study provides information on the electronic structure of nanotube-polymer assembly, revealing the charge transfer from P3HT to the nanotube. |
| Polymers, Vol. 3, Pages 1423-1432: Consolidation of Inorganic Precipitated Silica Gel Posted: 29 Aug 2011 12:00 AM PDT Colloidal gels are possible intermediates in the generation of highly porous particle systems. In the production process the gels are fragmented after their formation. These gel fragments compact to particles whose application-technological properties are determined by their size and porosity. In the case of precipitated silica gels, this consolidation process depends on temperature and pH, among other parameters. It is shown that these dependencies can be characterized by oedometer measurements. Originally, the oedometer test (one-dimensional compression test) stemmed from soil mechanics. It has proven to be an interesting novel examination method for gels. Quantitative data of the time-dependent shrinkage of gel samples can be obtained. The consolidation of the gels shows a characteristic dependence on the above parameters. |
| Posted: 29 Aug 2011 12:00 AM PDT Orbifloxacin is a fluoroquinolone with broad-spectrum antimicrobial activity, and belongs to the third generation of quinolones. Regarding the quality control of medicines, a validated microbiological assay for determination of orbifloxacin in pharmaceutical formulations has not as yet been reported. For this purpose, this paper reports the development and validation of a simple, sensitive, accurate and reproducible agar diffusion method to quantify orbifloxacin in tablet formulations. The assay is based on the inhibitory effect of orbifloxacin upon the strain of Staphylococcus aureus ATCC 25923 used as test microorganism. The results were treated statistically by analysis of variance and were found to be linear (r = 0.9992) in the selected range of 16.0–64.0 μg/mL, precise with relative standard deviation (RSD) of repeatability intraday = 2.88%, intermediate precision RSD = 3.33%, and accurate (100.31%). The results demonstrated the validity of the proposed bioassay, which allows reliable orbifloxacin quantitation in pharmaceutical samples and therefore can be used as a useful alternative methodology for the routine quality control of this medicine. |
| Posted: 29 Aug 2011 12:00 AM PDT The increased incidence of Multidrug-Resistant Mycobacterium tuberculosis (MDR-MT) requires the search for alternative antimycobacterial drugs. The main aim of this study was to evaluate the dichloromethane extract from Aristolochia brevipes (Rhizoma) and the compounds isolated from this extract against several mycobacterial strains, sensitive, resistant (monoresistant), and clinical isolates (multidrug-resistant), using the alamarBlue™ microassay. The extract was fractionated by column chromatography, yielding the following eight major compounds: (1) 6α-7-dehydro-N-formylnornantenine; (2) E/Z-N-formylnornantenine; (3) 7,9-dimethoxytariacuripyrone; (4) 9-methoxy-tariacuripyrone; (5) aristololactam I; (6) β-sitosterol; (7) stigmasterol; and (8) 3-hydroxy-α-terpineol. The structures of these compounds were elucidated by 1H- and 13C- (1D and 2D) Nuclear Magnetic Resonance (NMR) spectroscopy. This study demonstrates that the dichloromethane extract (rhizome) of A. brevipes possesses strong in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv (Minimum Inhibitory Concentration value [MIC], 12.5 µg/mL). The most active compound against all mycobacterial strains tested was the compound aristolactam I (5), with MIC values ranging between 12.5 and 25 µg/mL. To our knowledge, this the first report of antimycobacterial activity in this plant. |
| Posted: 29 Aug 2011 12:00 AM PDT The extract from Mitragyna speciosa has been widely used as an opium substitute, mainly due to its morphine-like pharmacological effects. This study investigated the effects of M. speciosa alkaloid extract (MSE) on human recombinant cytochrome P450 (CYP) enzyme activities using a modified Crespi method. As compared with the liquid chromatography-mass spectrometry method, this method has shown to be a fast and cost-effective way to perform CYP inhibition studies. The results indicated that MSE has the most potent inhibitory effect on CYP3A4 and CYP2D6, with apparent half-maximal inhibitory concentration (IC50) values of 0.78 µg/mL and 0.636 µg/mL, respectively. In addition, moderate inhibition was observed for CYP1A2, with an IC50 of 39 µg/mL, and weak inhibition was detected for CYP2C19. The IC50 of CYP2C19 could not be determined, however, because inhibition was |
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