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- IJMS, Vol. 12, Pages 5577-5591: New User-Friendly Approach to Obtain an Eisenberg Plot and Its Use as a Practical Tool in Protein Sequence Analysis
- MacPay Standard Edition 4.1.1 - Financial app for Swiss banks.. (Demo)
- @nonymous 1.1 - Send e-mail anonymously.. (Demo)
- MacPay Business Edition 4.1.1 - Pro version of financial app for Swiss banking system.. (Demo)
- Sensors, Vol. 11, Pages 8456-8468: Novel Wireless Sensor System for Monitoring Oxygen, Temperature and Respiration Rate of Horticultural Crops Post Harvest
- fp 4.71 - Xcode C++ implements unlimited length integers and more.. (Free)
- Zumba Fitness' reign of terror in UK charts is over, as are its chances of a record run at number one
- Ice Tales - Screenshots
- Max Payne 3 - Screenshots
- Algorithms, Vol. 4, Pages 155-182: Radio-Frequency Interference Detection and Mitigation Algorithms for Synthetic Aperture Radiometers
- Marine Drugs, Vol. 9, Pages 1469-1476: Capilloquinol: A Novel Farnesyl Quinol from the Dongsha Atoll Soft Coral Sinularia capillosa
- IJMS, Vol. 12, Pages 5565-5576: New Dye-Sensitized Solar Cells Obtained from Extracted Bracts of Bougainvillea Glabra and Spectabilis Betalain Pigments by Different Purification Processes
- IJMS, Vol. 12, Pages 5552-5564: Spectroscopic Behavior of Some A3B Type Tetrapyrrolic Complexes in Several Organic Solvents and Micellar Media
- The Vault
- Cocktail 5.0 - General maintenance and optimization utility.. (Shareware)
- SMARTReporter 2.7.0 - Hard drive pre-failure warning utility.. (Free)
- DesktopLyrics 1.3.5 - Displays current iTunes song lyrics on desktop.. (Free)
- Daylite 3.15 - Shared calendar, contacts, projects, meetings, notes and more.. (Demo)
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- The Haunted: Hell's Reach Q&A - Exclusive First Details
| Posted: 30 Aug 2011 12:00 AM PDT The Eisenberg plot or hydrophobic moment plot methodology is one of the most frequently used methods of bioinformatics. Bioinformatics is more and more recognized as a helpful tool in Life Sciences in general, and recent developments in approaches recognizing lipid binding regions in proteins are promising in this respect. In this study a bioinformatics approach specialized in identifying lipid binding helical regions in proteins was used to obtain an Eisenberg plot. The validity of the Heliquest generated hydrophobic moment plot was checked and exemplified. This study indicates that the Eisenberg plot methodology can be transferred to another hydrophobicity scale and renders a user-friendly approach which can be utilized in routine checks in protein–lipid interaction and in protein and peptide lipid binding characterization studies. A combined approach seems to be advantageous and results in a powerful tool in the search of helical lipid-binding regions in proteins and peptides. The strength and limitations of the Eisenberg plot approach itself are discussed as well. The presented approach not only leads to a better understanding of the nature of the protein–lipid interactions but also provides a user-friendly tool for the search of lipid-binding regions in proteins and peptides. |
| MacPay Standard Edition 4.1.1 - Financial app for Swiss banks.. (Demo) Posted: 30 Aug 2011 03:38 AM PDT  MacPay is a specialized application for Swiss banks and Postfinance customers. With MacPay, you can pay all your bills and execute multiple financial transactions from your Mac desktop. Output files are then uploaded to your bank or Postfinance via website. MacPay is localized in French, English, German, and Italian. Version 4.1.1:
Mac OS X 10.5 or later. Download Now This posting includes an audio/video/photo media file: Download Now |
| @nonymous 1.1 - Send e-mail anonymously.. (Demo) Posted: 30 Aug 2011 03:18 AM PDT  @nonymous is an anonymous email sender. You can send emails to any email with a sender address by your choice. Version 1.1:
Download Now This posting includes an audio/video/photo media file: Download Now |
| MacPay Business Edition 4.1.1 - Pro version of financial app for Swiss banking system.. (Demo) Posted: 30 Aug 2011 03:32 AM PDT  MacPay Business Edition is a pro version of our existing MacPay Standard payment management application. It adds the following features to the basic Swiss payment management functions of the Standard version: Full PDF scan and management of invoices. Payment data are extracted from the PDF and the PDF is linked to the payment and filed with it. Automatic transmission of payments to selected bank servers (Credit Suisse, Postfinance and Raiffeisen, most swiss banks will be connected in the near future). Usual file transmission is still available for non connected banks. Automatic download of account statements from the bank servers. Can also be used on a local network for multi-user environments. Version 4.1.1:
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| Posted: 30 Aug 2011 12:00 AM PDT In order to design optimal packages, it is of pivotal importance to determine the rate at which harvested fresh fruits and vegetables consume oxygen. The respiration rate of oxygen (RRO2) is determined by measuring the consumed oxygen per hour per kg plant material, and the rate is highly influenced by temperature and gas composition. Traditionally, RRO2 has been determined at discrete time intervals. In this study, wireless sensor networks (WSNs) were used to determine RRO2 continuously in plant material (fresh cut broccoli florets) at 5 °C, 10 °C and 20 °C and at modified gas compositions (decreasing oxygen and increasing carbon dioxide levels). Furthermore, the WSN enabled concomitant determination of oxygen and temperature in the very close vicinity of the plant material. This information proved a very close relationship between changes in temperature and respiration rate. The applied WSNs were unable to determine oxygen levels lower than 5% and carbon dioxide was not determined. Despite these drawbacks in relation to respiration analysis, the WSNs offer a new possibility to do continuous measurement of RRO2 in post harvest research, thereby investigating the close relation between temperature and RRO2. The conclusions are that WSNs have the potential to be used as a monitor of RRO2 of plant material after harvest, during storage and packaging, thereby leading to optimized consumer products. |
| fp 4.71 - Xcode C++ implements unlimited length integers and more.. (Free) Posted: 30 Aug 2011 03:05 AM PDT fp is an Xcode C++ project which implements unlimited length integers, multi-precision floating point numbers, and multi-precision complex numbers. It can calculate the usual transcendental functions, including the Gamma function and many special functions. I am releasing it without a restrictive license. Version 4.71:
Mac OS X 10.4.11 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 30 Aug 2011 02:58 AM PDT
Deus Ex: Human Revolution has ended Zumba Fitness' insanely long stay at the top of the UK all-formats chart. One week before Zumba would have equaled the record held by FIFA: Road to the World Cup from 1998 as the most consecutive weeks atop the UK charts. But that's not the only statistic of note. We know the main reason you get up every morning is in the hope some statistics of note come along, so you're going to love this. |
| Posted: 30 Aug 2011 03:36 AM PDT Full of challenging levels, dozens of achievements, an original 8-bit soundtrack and unique retro-cartoon graphics, Ice Tales is addictive. Ice Tales has settings for the casual gamer as well as more challenging settings for the avid gamer. Play it the way you like to play. FEATURES: - Journey across distant icebergs, angry volcanoes and an evil queen's palace. - Collect starfish, baskets of fish and other goodies to make it through the queen's evil mazes, earn bonuses and achievements. - Defend yourself from giant crabs, evil seals, hungry squid, angry sea birds, moonwalking polar bears and the ice queen herself. - Level select feature allows you to skip levels of the game you've already completed or play them again for a better score. - Old made new again game play: Full screen swipe to move and tap to jump mimic classic arcade games in a responsive, fun way. - Challenging retro arcade game play with 3 difficulty settings for the casual gamer to the avid gamer. - Challenge your friends with Game Center and OpenFeint Integration. * - Take a trip back in time. Cute retro-cartoon graphics optimized for Retina Display. * - Original 8-bit soundtrack. - Dozens of achievements. - Facebook and Twitter integration. |
| Posted: 30 Aug 2011 03:53 AM PDT New York, NY – March 23, 2009 – Rockstar Games, a publishing label of Take-Two Interactive Software, Inc. (NASDAQ: TTWO), is proud to announce that Max Payne 3 is currently in development and scheduled for a winter 2009 release on the Xbox 360® video game and entertainment system from Microsoft, PLAYSTATION®3 computer entertainment system and PC. Developed by Rockstar Vancouver, Max Payne 3 tells the story of a retired police detective embroiled in a world of corruption, turmoil and intense violence. The award-winning Max Payne franchise put players in the role of Max Payne, a hard-boiled New York City detective with a penchant for violence, out to avenge the death of his family. The latest installment delivers more of the classic elements and hyper-intense action that fans have come to love, while moving the story of Max in a new direction. "We're starting a new chapter of Max's life with this game," said Sam Houser, Founder of Rockstar Games. "This is Max as we've never seen him before, a few years older, more world-weary and cynical than ever. We experience the downward spiral of his life after the events of Max Payne 2 and witness his last chance for salvation." Since leaving the NYPD and New York itself behind, Max has drifted from bad to worse. Double-crossed and a long way from home, Max is now trapped in a city full of violence and bloodshed, using his weapons and instincts in a desperate search for the truth and a way out. Max Payne 3 will be available in winter 2009 for Xbox 360, PLAYSTATION 3 and PC. For more information, log onto www.rockstargames.com/maxpayne3. |
| Posted: 30 Aug 2011 12:00 AM PDT The European Space Agency (ESA) successfully launched the Soil Moisture and Ocean Salinity (SMOS) mission in November 2, 2009. SMOS uses a new type of instrument, a synthetic aperture radiometer named MIRAS that provides full-polarimetric multi-angular L-band brightness temperatures, from which regular and global maps of Sea Surface Salinity (SSS) and Soil Moisture (SM) are generated. Although SMOS operates in a restricted band (1400–1427 MHz), radio-frequency interference (RFI) appears in SMOS imagery in many areas of the world, and it is an important issue to be addressed for quality SSS and SM retrievals. The impact on SMOS imagery of a sinusoidal RFI source is reviewed, and the problem is illustrated with actual RFI encountered by SMOS. Two RFI detection and mitigation algorithms are developed (dual-polarization and full-polarimetric modes), the performance of the second one has been quantitatively evaluated in terms of probability of detection and false alarm (using a synthetic test scene), and results presented using real dual-polarization and full-polarimetric SMOS imagery. Finally, a statistical analysis of more than 13,000 L1b snap-shots is presented and discussed. |
| Posted: 30 Aug 2011 12:00 AM PDT Capilloquinol (1), possessing an unprecedented farnesyl quinoid skeleton, was isolated from the Dongsha Atoll soft coral Sinularia capillosa. The structure of capilloquinol was elucidated by extensive analysis of spectroscopic data. The cytotoxicity and antiviral activity against human cytomegalovirus of 1 was evaluated in vitro. |
| Posted: 30 Aug 2011 12:00 AM PDT The performance of a new dye-sensitized solar cell (DSSC) based in a natural dye extracted from the Bougainvillea spectabilis' bracts, is reported. The performance of this solar cell was compared with cells prepared using extract of the Bougainvillea glabra and mixture of both extracts; in both cases the pigments were betalains, obtained from Reddish-purple extract. These dyes were purified to different extents and used for the construction of solar cells that were electrically characterized. The materials were characterized using FTIR and UV-Vis. Solar cells were assembled using TiO2 thin film on indium tin oxide (ITO)-coated glass; a mesoporous film was sensitized with the Bougainvillea extracts. The obtained solar energy conversion efficiency was of 0.48% with a current density JSC of 2.29 mA/cm2 using an irradiation of 100 mW/cm2 at 25 °C. |
| Posted: 30 Aug 2011 12:00 AM PDT The paper presents spectral studies of some unsymmetrical A3B tetrapyrrolic, porphyrin-type complexes with Cu(II) and Zn(II) in different solvents and micellar media aimed at estimating their properties in connection with the living cell. The results indicate that the position of the absorption and emission peaks is mostly influenced by the central metal ion and less by the environmental polarity or the peripheric substituents of the porphyrinic core. The comparison between the overall absorption and emission spectra of the compounds in methanol or cyclohexane vs. direct and reverse Triton X micellar systems, respectively, suggests for all compounds the localization at the interface between the polyethylene oxide chains and the tert-octyl-phenyl etheric residue of the Triton X-100 molecules. These findings could be important when testing the compounds embedded in liposomes or other delivery systems to the targeted cell. |
| Posted: 30 Aug 2011 12:56 AM PDT Some times while gazing up at the celestial firmament, I realize that, out there in this big world of ours, there are thousands of unlucky 8 month-olds who have never experienced a JiG Casual Game Design Competition. It's a tragedy really. And while those poor tots might not be required to wait too much longer, we can takes some comfort in the 9 previous CGDC iterations each provide more than the daily requirement of epic that growing children need. This week, the JiG Vault features some personal favorites from past competions. Future entrants take note: you've got some tough acts to follow. |
| Cocktail 5.0 - General maintenance and optimization utility.. (Shareware) Posted: 29 Aug 2011 08:59 PM PDT  Cocktail is an app for OS X that lets users clean, repair and optimize their Macs. It is a powerful digital toolset that helps hundreds of thousands of Mac users around the world get the most out of their computers every day. The application serves up a perfect mix of maintenance tools and tweaks, all accessible through a clean and easy to use interface. Cocktail's features are arranged into five categories that helps you manage various aspects of your computer. It also comes with an automatic Pilot-mode that allows you to simply press a button and relax, knowing that Cocktail will take care of the rest. Cocktail (Lion Edition) requires OS X 10.7. Cocktail (Snow Leopard Edition) for OS X 10.6 and Cocktail (Leopard Edition) for OS X 10.5 are available for download from our website.
OS X 10.7 or later. Download Now This posting includes an audio/video/photo media file: Download Now |
| SMARTReporter 2.7.0 - Hard drive pre-failure warning utility.. (Free) Posted: 29 Aug 2011 08:59 PM PDT  SMARTReporter is an application that can warn you of some hard disk drive failures before they actually happen! It does so by periodically polling the S.M.A.R.T. status of your hard disk drive. S.M.A.R.T. (Self-Monitoring Analysis and Reporting Technology) is a technology built into most modern hard disk drives that acts as an "early warning system" for pending hard disk drive problems. SMARTReporter can notify you of impending hard disk drive failures by sending e-mails, displaying a warning dialog or executing an application. The current status of your hard disk drives is always displayed through the customizable menu item. Because SMARTReporter relies on the S.M.A.R.T. implementation of Mac OS X, it only supports ATA, SATA or eSATA hard disk drives, if you want S.M.A.R.T. support for your FireWire hard disk drive, send feedback to Apple. Please note that a S.M.A.R.T. alert doesn't mean that your HDD will completely fail for sure, nor can S.M.A.R.T. catch all possible HDD errors - it's just a very valuable indicator. Version 2.7.0:
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| DesktopLyrics 1.3.5 - Displays current iTunes song lyrics on desktop.. (Free) Posted: 29 Aug 2011 08:59 PM PDT  DesktopLyrics is an application that displays the lyrics of the song currently playing in "iTunes" right on your desktop. The lyrics for the song have to be set in iTunes, DesktopLyrics does nothing to fetch them if they aren't available in iTunes. If you don't want to type-in all your lyrics manually you can use an application like "Harmonic", "GimmieSomeTune" or "Get Lyrical" . Version 1.3.5:
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| Daylite 3.15 - Shared calendar, contacts, projects, meetings, notes and more.. (Demo) Posted: 29 Aug 2011 08:59 PM PDT  Daylite helps businesses organize themselves with tools such as shared calendars, contacts, tasks, projects, notes and more. Enable easy collaboration with features such as task and project delegation between users and never let things fall through the cracks. Create smart lists to find meaningful data fast - including delegated but uncompleted work. Work anywhere - in a networked office, from home or on the road. Read Daylite review at TUAW Version 3.15: Enhancements:
Mac OS X 10.4.11 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 29 Aug 2011 11:14 PM PDT Ferguson is the executive director of the American Chess School, gave the players, ages four and up, some quick instruction on basic strategy. This posting includes an audio/video/photo media file: Download Now |
| The Haunted: Hell's Reach Q&A - Exclusive First Details Posted: 29 Aug 2011 08:29 PM PDT The Haunted: Hell's Reach will be a third-person action game that pits you against the forces of Hell. Get the first details here.
The Haunted: Hell's Reach is a third-person action game that pits a team of human demon hunters against the legions of Hell itself. This new action game is being developed by the most recent winners of Epic's Make Something Unreal contest--a homegrown project that will be brought to market as a full-fledged, cooperative multiplayer game by publisher THQ for the PC, Xbox LIVE Arcade, and the PlayStation Network. Game director Michael Hegemann and creative director Gerhard Weihrauch explain.
Watch The Haunted: The Hell's Reach in motion. GameSpot: Give us an overview of The Haunted. What was the inspiration for making this game? Michael Hegemann: The Haunted: Hells Reach is a fast-paced, third-person shooter/brawler that knows no compromise. All Hell has broken loose and the forces of evil are rising up. As one of four badass demon hunters, you make a stand against the hellspawn with a huge arsenal of deadly weapons and melee combat [skills] to send the minions back to where they belong. The game can be played alone or together with your friends in various multiplayer modes.
Quite a few people said it looks influenced by the Dark Tower universe, especially the first book. And it is. That style is so perfectly described--it's so distinct and memorable that it sticks with you. The scenario is also heavily influenced by horror and action films as well as TV shows that most gamers of our generation watched as kids. It's like Evil Dead meets The A-Team. There is a trash/grindhouse vibe to it and we don't try to be uber-serious. It's all about the fun. Gerhard Weihrauch: In terms of gameplay, the biggest influence was definitely the games created by action mastermind Shinji Mikami of Platinum Games. He's one of my favorite developers! Resident Evil 4, God Hand, and Vanquish (all praised for their fantastic design) served as main sources of inspiration for The Haunted: Hells Reach. My goal was to combine elements of all those games into something new and interesting that fans of hardcore action games, like me, would enjoy playing. GS: We understand that The Haunted is a third-person action game about a war between humans and demons. Where and when does the game take place? Who are the primary characters in the conflict? MH: The game takes place in the near future when a demonic threat rises in haunted places that were once sanctuaries of evil. You play as a demon hunter who has to liberate these places, take them out of "Hell's reach," and prevent the demonic apocalypse. The fight takes you all around the world--from ghost towns, high mountain castles, ancient excavation sites, and even to Hell where you face the demon lord Abaddon. The characters (Bruce, Hector, Jacob and Caleb) are four demon hunters who once bound their lives to soulstones and fight the purest form of evil in order to redeem themselves for their questionable past lives. They were villains in our world and are now heroes in theirs. Each of them has his own motivation in dealing with the demonic threat, which they express once in a while when killing minions. Jacob has found faith and sees himself as weapon of God; Hector is happy when things blow up; for Bruce, killing is not unlike professional engineering; and Caleb has his wisdom and deeper knowledge of what really goes on. Together they stand as one! Inspiration comes from over-the-top style action heroes from the 1980's, and newer sources like 300, as well as game characters like Kratos. We try to get as far away from military-type characters as possible, since there are enough obedient soldiers already! GS: Why go third-person, rather than being a first-person shooter? What does this different perspective let you do that a first-person perspective wouldn't? GW: One of the key advantages of a third-person perspective is that you can see your character and everything around him. This grants players a much better overview of the gameplay situation and lets him judge threats more easily. In first-person shooters, the field of vision is always the limiting factor in terms of information that you can give players about what's going on, unless you add a lot of additional "helpers" in the form of heads-up display elements. Another important gameplay element in The Haunted: Hells Reach is our melee system, which includes various attacks and executions. Following up a combat roll with an uppercut or combining a back elbow into a back kick just wouldn't work very well in first-person. At the very least, it would look pretty silly and feek disorienting. Take Mirror's Edge for example--as awesome as this game was, the first-person melee elements just didn't work very well. So from a design perspective, a third-person view just lets us do more interesting things with gameplay than a first-person perspective. Also, I think that players connect more with their characters if they can see them. GS: We understand that The Haunted is going to focus primarily on team-based multiplayer. Will there be any single-player component? If so, could you tell us about it?
MH: We are a tiny independent team and don't really have the resources or people required to create a full-blown single-player campaign that can compete with actual big-budget productions. Therefore we set the focus on the arcade and multiplayer experience. A lot of games have "horde" and "play as the monster" modes these days, but we aim to be the definitive game that is really focused on these particular game types. We don't need to make any tradeoffs since we are not a working with a huge intellectual property, so we don't need to as be careful about what we do. We can take risks and try out new things. GS: Give us an overview of the game's multiplayer modes. What will the game offer that's different from multiplayer team action games that are out there now? MH: The game will come with four multiplayer modes in the initial release. Inferno is our default co-op mode. Up to four human players have to make a stand against the demons and send as many minions as possible back to Hell, while redeeming the souls of fallen comrades by destroying their soulstones. This mode offers intense and frantic action that doesn't force players to play cooperatively, but rewards them for working together. There's also a little built-in competition between the human players with regards to who can score the most points and kills the most minions--it's more like the friendly competition between Legolas and Gimli in the Lord of the Rings movies than head-to-head competition, though.
Survival is a variation of Inferno in which the humans need to survive as long as possible against an ever-growing horde of minions until all humans are dead. Battle and Demonizer are modes where players can spawn and play as the hellspawn. Battle is a competitive mode that pits up to four humans against up to four demons, while Demonizer puts a little twist on the co-op formula. In Demonizer, eachdead human turns into a demon who tries to hunt down the other humans. If you manage to kill one, you respawn as a human. The player that stays human for the longest time wins. I should mention that hosting and joining multiplayer games is really easy and painless. Quite a few games make it feel like work to get into an online game, and we don't want that. [For the PC version,] you won't need to log into anything else than Steam--a few clicks and you're in the game. We also support dedicated servers. GS: So you'll play as human characters fighting demon hordes in the game. Will all the weapons you use be conventional firearms? Any unusual or experimental high-tech weaponry, or magic powers? MH: The humans are rely on traditional firearms and close-combat weapons like a chainsaw or the infamous "witchhammer." There are 36 distinct weapons in total that you can acquire through upgrades you get after shedding enough minion blood. Each weapon has a unique feel to it. It's not just a bunch of full-auto weapons with different models. To make the two factions more distinct, only the demons use magical and arcane powers. Everything the humans can do is theoretically possible in the real world. For instance, one of the more unusual weapons is the nitrogen launcher, which can freeze enemies instantly and turns them into ice blocks that players can then smash. GW: Aside from conventional weapons, the game offers a great variety of melee moves. The system is similar to fighting games, in which different moves have different effects. First, you melee a minion to stun it--and while your target is stunned, you can perform a brutal execution attack that not only kills, but also has the useful property of hurling away all nearby enemies to create space. Every melee attack can be charged up and turned into a more-powerful instant-kill move. However, some monsters become enraged when you melee them too often and will become immune to it. Other monsters are immune to bullets and can only be taken down by melee. This will constantly challenge players to adapt to new situations and guarantee some variety. GS: We also understand that in some of the game's modes, players will be able to play as demons. How will demon characters differ from human characters? MH: Playing as a demon is part of the Battle and Demonizer modes. Demons are the spiritual entities, similar to the smoke monster from Lost, while minions are the physical entities. You can also play as a minion in the third-person perspective as well. The minions are more like demonic zombies. They are just much more fun to kill than a bunch of tentacle monsters. Each of the environments also has a cataclysmic event, such as a meteor shower or a raging thunderstorm, which provides another gameplay-affecting threat. These events can be triggered by demon players to cause even more havoc. GS: When will the game be released, and for what platforms? Any chance of seeing a console release? MH: The game is scheduled for release on Xbox LIVE Arcade and the PlayStation Network sometime next year. We will keep updating the PC version, and all the improvements and extra content will be in the console releases as well. GS: Finally, is there anything you'd like to add about the game? GW: It should be mentioned that we will actively support mods and that we look forward to all the crazy things the community will come up with. If you have ideas or comments feel free to visit us on our website.
MH: It's about kicking ass, and not getting your ass kicked. It's like "Resident Gears of Left 4 Evil Dead" turned up to eleven! If you're into action games and want an insanely fun third-person shooter without restrictions, clunky movement, and too much military dude-bros…you should check out The Haunted: Hells Reach! GS: Thank you. Read and Post Comments | Get the full article at GameSpot "The Haunted: Hell's Reach Q&A - Exclusive First Details" was posted by Staff on Mon, 29 Aug 2011 20:29:07 -0700 |
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