Games |
- VUWER 1.6.2 - Remotely track lost or stolen Macs.. (Free)
- WindowClipMBI 1.1.9 - Menu bar application for creating clipboard snapshots of the windows on your Mac.. (Demo)
- TAO 1.8.26 - Information outliner (was FO Outliner).. (Shareware)
- NeO 1.0.21.2 - Information outlining and organizing tool.. (Demo)
- Sensors, Vol. 12, Pages 12606-12633: Efficient Security Mechanisms for mHealth Applications Using Wireless Body Sensor Networks
- Sensors, Vol. 12, Pages 12588-12605: Comprehensive Context Recognizer Based on Multimodal Sensors in a Smartphone
- IJMS, Vol. 13, Pages 11681-11693: Cellular Delivery of Doxorubicin via pH-Controlled Hydrazone Linkage Using Multifunctional Nano Vehicle Based on Poly(β-L-Malic Acid)
- IJMS, Vol. 13, Pages 11666-11680: Combination of Oxyanion Gln114 Mutation and Medium Engineering to Influence the Enantioselectivity of Thermophilic Lipase from Geobacillus zalihae
- Materials, Vol. 5, Pages 1661-1685: Natural Melanogenesis Inhibitors Acting Through the Down-Regulation of Tyrosinase Activity
- Qrth-phyl out now, instantly wins 'Best Xbox Live Indie Game In Bloody Ages' award
- Materials, Vol. 5, Pages 1654-1660: Pozzolanic Activity Assessment of LUSI (LUmpur SIdoarjo) Mud in Semi High Volume Pozzolanic Mortar
- Materials, Vol. 5, Pages 1635-1653: Review of Random Phase Encoding in Volume Holographic Storage
- IJMS, Vol. 13, Pages 11643-11665: Optimization to Low Temperature Activity in Psychrophilic Enzymes
- Nono Sparks Genesis
- Sky Night
- Energies, Vol. 5, Pages 3586-3607: Harmonic Analysis and Fault-Tolerant Capability of a Semi-12-Phase Permanent-Magnet Synchronous Machine Used for EVs
- Energies, Vol. 5, Pages 3573-3585: Performance Analysis and Optimization of a Solar Powered Stirling Engine with Heat Transfer Considerations
- Energies, Vol. 5, Pages 3550-3572: Energy Efficiency in the Brazilian Pulp and Paper Industry
- IJMS, Vol. 13, Pages 11610-11642: Experimental Aspects of Colloidal Interactions in Mixed Systems of Liposome and Inorganic Nanoparticle and Their Applications
- Molecules, Vol. 17, Pages 11139-11145: Proximate Composition, Nutritional Attributes and Mineral Composition of Peperomia pellucida L. (Ketumpangan Air) Grown in Malaysia
| VUWER 1.6.2 - Remotely track lost or stolen Macs.. (Free) Posted: 17 Sep 2012 02:50 AM PDT  VUWER (pronounced like "viewer") is an application designed to remotely track your MacBook Air or MacBook Pro (or any other Apple computer) in the event that it is lost or stolen. VUWER is not foolproof, but it is reasonably secure, easy to implement, and costs nothing but a little time and effort to set up. VUWER is free of charge, open source, and relies on standard OS X commands and readily available freeware applications for installation and operation. Also, since VUWER is written in Applescript, it is relatively easy to modify or enhance in any way you choose. You are in complete control of where the captured data from your stolen laptop is sent and how it is accessed; data can be transmitted either by email or by secure file copy to another computer account. You can remotely capture screenshots, iSight/FaceTime camera images, and IP geolocation data from your laptop, and separately choose their respective repetition intervals. No third-party intermediary is required to track your laptop. VUWER eliminates any possibility of an unscrupulous person at a theft-recovery company snooping on you. See http://stumpy.vuse.vanderbilt.edu/vuwer.htm for more information. Please submit comments and bug reports to tim.holman (at) vanderbilt.edu.
Mac OS X 10.4.11 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 17 Sep 2012 02:46 AM PDT  WindowClipMBI is a Mac menu bar application for creating clipboard snapshots of the windows on your Mac in any application, for any application, and more. Features include: scaling, composite, trimmed composites, filter effects, timed shots. Using its special features WindowClipMBI can create screenshots not possible (or not as easily) with other methods. Use the preference window, or the menu itself, to specify various options such as: scaling, reflections, showing cursor in screen shots, include Desktop windows, ignore framing effects like shadows, and creating an opaque image. WindowClipMBI is a member of the Limit Point Software Utilities bundle. See http://www.limit-point.com/Utilities.html for a complete list of available utilities included. Version 1.1.9:
Mac OS X 10.4.11 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| TAO 1.8.26 - Information outliner (was FO Outliner).. (Shareware) Posted: 17 Sep 2012 02:43 AM PDT  TAO is a powerful outliner/organizer where chunks of information can easily be managed and organized as items. TAO supports basic outliner facilities, such as creating, moving, sorting, grouping, combining and gathering items. Also the following useful facilities help you organize items:
Version 1.8.26:
Mac OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| NeO 1.0.21.2 - Information outlining and organizing tool.. (Demo) Posted: 17 Sep 2012 02:35 AM PDT  NeO is a powerful outliner built for Mac OS X. Using NeO, you can efficiently manage and organize pieces of information. NeO supports basic outliner facilities, such as creating, moving, sorting, grouping, combining and gathering items. And the useful facilities help you manage and organize information.
Version 1.0.21.2:
Mac OS X 10.6.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Posted: 17 Sep 2012 12:00 AM PDT Recent technological advances in wireless communications and physiological sensing allow miniature, lightweight, ultra-low power, intelligent monitoring devices, which can be integrated into a Wireless Body Sensor Network (WBSN) for health monitoring. Physiological signals of humans such as heartbeats, temperature and pulse can be monitored from a distant location using tiny biomedical wireless sensors. Hence, it is highly essential to combine the ubiquitous computing with mobile health technology using wireless sensors and smart phones to monitor the well-being of chronic patients such as cardiac, Parkinson and epilepsy patients. Since physiological data of a patient are highly sensitive, maintaining its confidentiality is highly essential. Hence, security is a vital research issue in mobile health (mHealth) applications, especially if a patient has an embarrassing disease. In this paper a three tier security architecture for the mHealth application is proposed, in which light weight data confidentiality and authentication protocols are proposed to maintain the privacy of a patient. Moreover, considering the energy and hardware constraints of the wireless body sensors, low complexity data confidential and authentication schemes are designed. Performance evaluation of the proposed architecture shows that they can satisfy the energy and hardware limitations of the sensors and still can maintain the secure fabrics of the wireless body sensor networks. Besides, the proposed schemes can outperform in terms of energy consumption, memory usage and computation time over standard key establishment security scheme. |
| Posted: 17 Sep 2012 12:00 AM PDT Recent developments in smartphones have increased the processing capabilities and equipped these devices with a number of built-in multimodal sensors, including accelerometers, gyroscopes, GPS interfaces, Wi-Fi access, and proximity sensors. Despite the fact that numerous studies have investigated the development of user-context aware applications using smartphones, these applications are currently only able to recognize simple contexts using a single type of sensor. Therefore, in this work, we introduce a comprehensive approach for context aware applications that utilizes the multimodal sensors in smartphones. The proposed system is not only able to recognize different kinds of contexts with high accuracy, but it is also able to optimize the power consumption since power-hungry sensors can be activated or deactivated at appropriate times. Additionally, the system is able to recognize activities wherever the smartphone is on a human's body, even when the user is using the phone to make a phone call, manipulate applications, play games, or listen to music. Furthermore, we also present a novel feature selection algorithm for the accelerometer classification module. The proposed feature selection algorithm helps select good features and eliminates bad features, thereby improving the overall accuracy of the accelerometer classifier. Experimental results show that the proposed system can classify eight activities with an accuracy of 92.43%. |
| Posted: 17 Sep 2012 12:00 AM PDT Doxorubicin (DOX) is currently used in cancer chemotherapy to treat many tumors and shows improved delivery, reduced toxicity and higher treatment efficacy when being part of nanoscale delivery systems. However, a major drawback remains its toxicity to healthy tissue and the development of multi-drug resistance during prolonged treatment. This is why in our work we aimed to improve DOX delivery and reduce the toxicity by chemical conjugation with a new nanoplatform based on polymalic acid. For delivery into recipient cancer cells, DOX was conjugated via pH-sensitive hydrazone linkage along with polyethylene glycol (PEG) to a biodegradable, non-toxic and non-immunogenic nanoconjugate platform: poly(β-L-malic acid) (PMLA). DOX-nanoconjugates were found stable under physiological conditions and shown to successfully inhibit in vitro cancer cell growth of several invasive breast carcinoma cell lines such as MDA-MB-231 and MDA-MB- 468 and of primary glioma cell lines such as U87MG and U251. |
| Posted: 17 Sep 2012 12:00 AM PDT The substitution of the oxyanion Q114 with Met and Leu was carried out to investigate the role of Q114 in imparting enantioselectivity on T1 lipase. The mutation improved enantioselectivity in Q114M over the wild-type, while enantioselectivity in Q114L was reduced. The enantioselectivity of the thermophilic lipases, T1, Q114L and Q114M correlated better with log p as compared to the dielectric constant and dipole moment of the solvents. Enzyme activity was good in solvents with log p < 3.5, with the exception of hexane which deviated substantially. Isooctane was found to be the best solvent for the esterification of (R,S)-ibuprofen with oleyl alcohol for lipases Q114M and Q114L, to afford E values of 53.7 and 12.2, respectively. Selectivity of T1 was highest in tetradecane with E value 49.2. Solvents with low log p reduced overall lipase activity and dimethyl sulfoxide (DMSO) completely inhibited the lipases. Ester conversions, however, were still low. Molecular sieves employed as desiccant were found to adversely affect catalysis in the lipase variants, particularly in Q114M. The higher desiccant loading also increased viscosity in the reaction and further reduced the efficiency of the lipase-catalyzed esterifications. |
| Posted: 17 Sep 2012 12:00 AM PDT Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human skin. A key enzyme, tyrosinase, catalyzes the first and only rate-limiting steps in melanogenesis, and the down-regulation of enzyme activity is the most reported method for the inhibition of melanogenesis. Because of the cosmetically important issue of hyperpigmentation, there is a big demand for melanogenesis inhibitors. This encourages researchers to seek potent melanogenesis inhibitors for cosmetic uses. This article reviews melanogenesis inhibitors that have been recently discovered from natural sources. The reaction mechanisms of the inhibitors on tyrosinase activity are also discussed. |
| Qrth-phyl out now, instantly wins 'Best Xbox Live Indie Game In Bloody Ages' award Posted: 17 Sep 2012 02:06 AM PDT Qrth-phyl is a game and it has recently been released for PC and Xbox 360 Indies. It's an inspired re-imagining of archaic phone classic Snake, blended |
| Posted: 17 Sep 2012 12:00 AM PDT LUSI mud obtained from the mud volcano in Sidoarjo, Indonesia, is a viable aluminosilicate material to be utilized as pozzolanic material. LUSI is an abbreviation of the local name of the mud, i.e., Lumpur Sidoarjo, meaning Sidoarjo mud. This paper reports the results of an investigation to assess the pozzolanic activity of LUSI mud, especially in semi high volume pozzolanic mortar. In this case, the amount of mud incorporated is between 30% to 40% of total cementitious material, by mass. The content of SiO2 in the mud is about 30%, whilst the total content of SiO2, Fe2O3 and Al2O3 is more than 70%. Particle size and degree of partial cement replacement by treated LUSI mud affect the compressive strength, the strength activity index (SAI), the rate of pozzolanic activity development, and the workability of mortar incorporating LUSI mud. Manufacturing semi high volume LUSI mud mortar, up to at least 40% cement replacement, is a possibility, especially with a smaller particle size of LUSI mud, less than 63 μm. The use of a larger percentage of cement replacement by LUSI mud does not show any adverse effect on the water demand, as the flow of the fresh mortar increased with the increase of percentage of LUSI mud usage. |
| Materials, Vol. 5, Pages 1635-1653: Review of Random Phase Encoding in Volume Holographic Storage Posted: 17 Sep 2012 12:00 AM PDT Random phase encoding is a unique technique for volume hologram which can be applied to various applications such as holographic multiplexing storage, image encryption, and optical sensing. In this review article, we first review and discuss diffraction selectivity of random phase encoding in volume holograms, which is the most important parameter related to multiplexing capacity of volume holographic storage. We then review an image encryption system based on random phase encoding. The alignment of phase key for decryption of the encoded image stored in holographic memory is analyzed and discussed. In the latter part of the review, an all-optical sensing system implemented by random phase encoding and holographic interconnection is presented. |
| IJMS, Vol. 13, Pages 11643-11665: Optimization to Low Temperature Activity in Psychrophilic Enzymes Posted: 17 Sep 2012 12:00 AM PDT Psychrophiles, i.e., organisms thriving permanently at near-zero temperatures, synthesize cold-active enzymes to sustain their cell cycle. These enzymes are already used in many biotechnological applications requiring high activity at mild temperatures or fast heat-inactivation rate. Most psychrophilic enzymes optimize a high activity at low temperature at the expense of substrate affinity, therefore reducing the free energy barrier of the transition state. Furthermore, a weak temperature dependence of activity ensures moderate reduction of the catalytic activity in the cold. In these naturally evolved enzymes, the optimization to low temperature activity is reached via destabilization of the structures bearing the active site or by destabilization of the whole molecule. This involves a reduction in the number and strength of all types of weak interactions or the disappearance of stability factors, resulting in improved dynamics of active site residues in the cold. Considering the subtle structural adjustments required for low temperature activity, directed evolution appears to be the most suitable methodology to engineer cold activity in biological catalysts. |
| Posted: 17 Sep 2012 12:40 AM PDT  Solve various board puzzles and make sure you use the exact number of blocks on each puzzle! |
| Posted: 17 Sep 2012 12:24 AM PDT  A past-paced pixel-art sky shooter. Fly the steampunk plane, battle enemies and upgrade your plane! |
| Posted: 17 Sep 2012 12:00 AM PDT This paper deals with a fault-tolerant semi-12-phase permanent-magnet synchronous machine (PMSM) used for electric vehicles. High fault-tolerant and low toque ripple features are achieved by employing fractional slot concentrated windings (FSCWs) and open windings. Excessive magnetomotive force (MMF) harmonic components can lead to thermal demagnetization of rotor magnets as well as high core loss. An improved all-teeth-wound winding disposition that changes the winding factor of each harmonic is applied to suppress harmonics. A relatively large slot leakage inductance that limits the short-circuit current (SCC) induced in the short-circuited winding is proposed to deal with short-circuit fault. Fault-tolerant controls up to two phases open circuited are investigated in this paper based on keeping the same torque-producing MMF. The fault-tolerant control strategies corresponding to each faulty mode are studied and compared to ensure high performance operation. |
| Posted: 17 Sep 2012 12:00 AM PDT This paper investigates the optimization of the performance of a solar powered Stirling engine based on finite-time thermodynamics. Heat transference in the heat exchangers between a concentrating solar collector and the Stirling engine is studied. The irreversibility of a Stirling engine is considered with the heat transfer following Newton's law. The power generated by a Stirling engine is used as an objective function for maximum power output design with the concentrating solar collector temperature and the engine thermal efficiency as the optimization parameters. The maximum output power of engine and its corresponding system parameters are determined using a genetic algorithm. |
| Energies, Vol. 5, Pages 3550-3572: Energy Efficiency in the Brazilian Pulp and Paper Industry Posted: 17 Sep 2012 12:00 AM PDT Industrial energy efficiency has received increasing attention in many countries because of its importance in the pursuit of energy supply security, increased economic competitiveness and in the mitigation of greenhouse gases emissions. This paper aimed to evaluate the energy consumption development of the Brazilian pulp and paper industry through an energy decomposition analysis and an energy efficiency index approach over a 30 years period. An international comparison with other important paper-producing countries (i.e., Canada, United States of America, Finland and Sweden) was carried out. It was concluded that despite a significant increase in the energy efficiency levels, responsible for 5.6 PJ savings in electricity consumption and for 38.6 PJ savings in fuels consumption between 1979 and 2009, a saving potential of 7.8 PJ and 146.2 PJ related to the annual consumption of electricity and fuels, respectively, could be identified in the Brazilian pulp and paper industry. Among the countries evolved in the international comparison, both the Swedish and Finnish industries were the most efficient, followed by the Brazilian, American and Canadian, the latter being the only one where there was a reduction in the energy efficiency levels from 1979 to 2009. |
| Posted: 17 Sep 2012 12:00 AM PDT In the past few years, growing attention has been devoted to the study of the interactions taking place in mixed systems of phospholipid membranes (for instance in the form of vesicles) and hard nanoparticles (NPs). In this context liposomes (vesicles) may serve as versatile carriers or as a model system for biological membranes. Research on these systems has led to the observation of novel hybrid structures whose morphology strongly depends on the charge, composition and size of the interacting colloidal species as well as on the nature (pH, ionic strength) of their dispersing medium. A central role is played by the phase behaviour of phospholipid bilayers which have a tremendous influence on the liposome properties. Another central aspect is the incorporation of nanoparticles into vesicles, which is intimately linked to the conditions required for transporting a nanoparticle through a membrane. Herein, we review recent progress made on the investigations of the interactions in liposome/nanoparticle systems focusing on the particularly interesting structures that are formed in these hybrid systems as well as their potential applications. |
| Posted: 17 Sep 2012 12:00 AM PDT This study presents the proximate and mineral composition of Peperomia pellucida L., an underexploited weed plant in Malaysia. Proximate analysis was performed using standard AOAC methods and mineral contents were determined using atomic absorption spectrometry. The results indicated Peperomia pellucida to be rich in crude protein, carbohydrate and total ash contents. The high amount of total ash (31.22%) suggests a high-value mineral composition comprising potassium, calcium and iron as the main elements. The present study inferred that Peperomia pellucida would serve as a good source of protein and energy as well as micronutrients in the form of a leafy vegetable for human consumption. |
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