вторник, 18 сентября 2012 г.

Games

Games


Earn to Die - Videos and Trailers

Posted: 18 Sep 2012 03:40 AM PDT

Earn to Die trailer.

Soldier vs. Aliens - Videos and Trailers

Posted: 18 Sep 2012 03:54 AM PDT

Soldier vs. Aliens official trailer.

Townsmen - Videos and Trailers

Posted: 18 Sep 2012 03:57 AM PDT

Townsmen official trailer.

NBA LIVE 13 - Videos and Trailers

Posted: 18 Sep 2012 03:47 AM PDT

First look trailer.

Snappy Dragons 2 - Videos and Trailers

Posted: 18 Sep 2012 03:52 AM PDT

Snappy Dragons 2 official trailer.

Rock Beat Lasers - Screenshots

Posted: 18 Sep 2012 03:43 AM PDT

There are 48 ready-to-remix loops for standard free version(3 songs) and 112 loops for one album(7 songs, In-App Purchase needed). And for the gaming, there're strict song sequences that lets you play along and build a song. 16 pads on upper side will play & show you the sequence or half sequence first, then you'll play on the another 16 pads below. And all  hits, misses & replays will be calculated for your final score. When you get to climax of the song, whole visual atmosphere will change and some of the songs will play the laser show like strobe lightings in the club.

Space Holiday - Videos and Trailers

Posted: 18 Sep 2012 03:54 AM PDT

Space Holiday official trailer.

Pulma 3D Puzzle - Screenshots

Posted: 18 Sep 2012 03:17 AM PDT

Features
- 3D puzzles - a new revolutionary way to play
- Lots of challenging levels
- A peaceful game world
- Play at your own pace
- Fun for families and players of all ages

March of the Eagles - Videos and Trailers

Posted: 18 Sep 2012 03:45 AM PDT

March of the Eagles announcement trailer.

Pulma 3D Puzzle - Videos and Trailers

Posted: 18 Sep 2012 03:50 AM PDT

Pulma 3D Puzzle trailer.

Biology, Vol. 1, Pages 439-459: Why Assembling Plant Genome Sequences Is So Challenging

Posted: 18 Sep 2012 12:00 AM PDT

In spite of the biological and economic importance of plants, relatively few plant species have been sequenced. Only the genome sequence of plants with relatively small genomes, most of them angiosperms, in particular eudicots, has been determined. The arrival of next-generation sequencing technologies has allowed the rapid and efficient development of new genomic resources for non-model or orphan plant species. But the sequencing pace of plants is far from that of animals and microorganisms. This review focuses on the typical challenges of plant genomes that can explain why plant genomics is less developed than animal genomics. Explanations about the impact of some confounding factors emerging from the nature of plant genomes are given. As a result of these challenges and confounding factors, the correct assembly and annotation of plant genomes is hindered, genome drafts are produced, and advances in plant genomics are delayed.

Cloud Mate 1.2 - Add a Finder like interface to iCloud.. (Commercial)

Posted: 18 Sep 2012 02:58 AM PDT



Cloud Mate ... iCloud is great. iCloud splits all your content up by the App that created it. iCloud hides your Photo Stream. Cloud Mate sets those files free!

Here are just some of the reasons we think you'll love Cloud Mate

  • Copying or Moving files between iCloud applications without running the Apps? No problem.
  • Moving files in or out of iCloud without running the Apps? No problem.
  • Getting the latest image from PhotoStream without opening iPhoto? No Problem.
  • Backing up save game files from your iOS games? No problem.
  • Finding that e-mail you printed as PDF from Mail and saved to iCloud? No Problem.
For the expert user we've even added some System Services to make it easy to move or copy files to iCloud anywhere where file services are available. Coda 2. Transmit. Finder. Wherever!

Version 1.2:
  • Improved navigation with back/forward and path drop-downs.
  • Added "Organise by…" options to the toolbar.
  • Introduced OS X 10.8 notifications for changed documents in your iCloud including ability to chose which apps notify of changes.
  • Start-up performance greatly improved.
  • Added the ability to check for and download Cloud Mate updates.
  • Cloud Mate now remains running when its window is closed.
  • Fixed an issue where the name of a known app sometimes returned the bundle display name.
  • Fixed a bug where apps that were not immediately recognised would not automatically update when changes occurred in iCloud.
  • Fixed a bug where keyboard navigation of apps would not work.
  • Fixed an issue where window size and layout was not remembered correctly between runs.
  • Fixed an issue where desired icon size was not remembered between invocations.
  • Fixed an issue where the Quick Look popover may be too small.


  • OS X 10.8 or later
  • iCloud Account
  • Photo Stream enabled (for Photo Stream features, iPhoto not required)


Download Now

Entropy, Vol. 14, Pages 1717-1770: Black Holes, Cosmological Solutions, Future Singularities, and Their Thermodynamical Properties in Modified Gravity Theories

Posted: 18 Sep 2012 12:00 AM PDT

Along this review, we focus on the study of several properties of modified gravity theories, in particular on black-hole solutions and its comparison with those solutions in General Relativity, and on Friedmann–Lemaˆıtre–Robertson–Walker metrics. The thermodynamical properties of fourth order gravity theories are also a subject of this investigation with special attention on local and global stability of paradigmatic f(R) models. In addition, we revise some attempts to extend the Cardy–Verlinde formula, including modified gravity, where a relation between entropy bounds is obtained. Moreover, a deep study on cosmological singularities, which appear as a real possibility for some kind of modified gravity theories, is performed, and the validity of the entropy bounds is studied.

Sustainability, Vol. 4, Pages 2293-2316: Modular Lead-Bismuth Fast Reactors in Nuclear Power

Posted: 18 Sep 2012 12:00 AM PDT

On the basis of the unique experience of operating reactors with heavy liquid metal coolant–eutectic lead-bismuth alloy in nuclear submarines, the concept of modular small fast reactors SVBR-100 for civilian nuclear power has been developed and validated. The features of this innovative technology are as follows: a monoblock (integral) design of the reactor with fast neutron spectrum, which can operate using different types of fuel in various fuel cycles including MOX fuel in a self-providing mode. The reactor is distinct in that it has a high level of self-protection and passive safety, it is factory manufactured and the assembled reactor can be transported by railway. Multipurpose application of the reactor is presumed, primarily, it can be used for regional power to produce electricity, heat and for water desalination. The Project is being realized within the framework of state-private partnership with joint venture OJSC "AKME-Engineering" established on a parity basis by the State Atomic Energy Corporation "Rosatom" and the Limited Liability Company "EuroSibEnergo".

Sustainability, Vol. 4, Pages 2270-2292: Engineering Sustainability: A Technical Approach to Sustainability

Posted: 18 Sep 2012 12:00 AM PDT

Sustainability is a critically important goal for human activity and development. Sustainability in the area of engineering is of great importance to any plans for overall sustainability given 1) the pervasiveness of engineering activities in societies, 2) their importance in economic development and living standards, and 3) the significant impacts that engineering processes and systems have had, and continue to have, on the environment. Many factors that need to be considered and appropriately addressed in moving towards engineering sustainability are examined in this article. These include appropriate selection of resources bearing in mind sustainability criteria, the use of sustainable engineering processes, enhancement of the efficiency of engineering processes and resource use, and a holistic adoption of environmental stewardship in engineering activities. In addition, other key sustainability measures are addressed, such as economics, equity, land use, lifestyle, sociopolitical factors and population. Conclusions are provided related both to pathways for engineering sustainability and to the broader ultimate objective of sustainability.

Information, Vol. 3, Pages 442-471: Counting Electric Sheep: Understanding Information in the Context of Media Ecology

Posted: 18 Sep 2012 12:00 AM PDT

In the field of media ecology, defined as the study of media as environments, media and medium, and ecology and environment are key terms, while information, although commonly employed, is generally used without reference to a specific definition. This article examines the mostly implicit assumptions about and understandings of the term information in the context of the field of media ecology. Information can be seen as a synonym or subset of content or message, can be divided into different orders or levels of content/communication and relationship/medium, and on both levels is dependent on and altered by changes in technology, code, and form. Although sometimes discussed as if it were a substance, information is best understood as a function of communication, which in turn is a function of mediation. As a function of mediated communication, information is closely associated with news and control. Information is also considered the defining characteristic of our contemporary period, but is best understood as a product of electricity, electric technology, and the electronic media. As we have moved from orality to literacy to electricity, so too has the emphasis shifted from wisdom to knowledge to information. Despite popular celebration, this evolution is not an unmitigated good, and what is needed is a balanced media environment.

Cancers, Vol. 4, Pages 945-968: The Expression of Embryonic Liver Development Genes in Hepatitis C Induced Cirrhosis and Hepatocellular Carcinoma

Posted: 18 Sep 2012 12:00 AM PDT

Hepatocellular carcinoma (HCC) remains a difficult disease to study even after a decade of genomic analysis. Patient and disease heterogeneity, differences in statistical methods and multiple testing issues have resulted in a fragmented understanding of the molecular basis of tumor biology. Some researchers have suggested that HCC appears to share pathways with embryonic development. Therefore we generated targeted hypotheses regarding changes in developmental genes specific to the liver in HCV-cirrhosis and HCV-HCC. We obtained microarray studies from 30 patients with HCV-cirrhosis and 49 patients with HCV-HCC and compared to 12 normal livers. Genes specific to non-liver development have known associations with other cancer types but none were expressed in either adult liver or tumor tissue, while 98 of 179 (55%) genes specific to liver development had differential expression between normal and cirrhotic or HCC samples. We found genes from each developmental stage dysregulated in tumors compared to normal and cirrhotic samples. Although there was no single tumor marker, we identified a set of genes (Bone Morphogenetic Protein inhibitors GPC3, GREM1, FSTL3, and FST) in which at least one gene was over-expressed in 100% of the tumor samples. Only five genes were differentially expressed exclusively in late-stage tumors, indicating that while developmental genes appear to play a profound role in cirrhosis and malignant transformation, they play a limited role in late-stage HCC.

Toxins, Vol. 4, Pages 729-747: Interaction between Shiga Toxin and Monoclonal Antibodies: Binding Characteristics and in Vitro Neutralizing Abilities

Posted: 18 Sep 2012 12:00 AM PDT

Monoclonal antibodies (MAbs) have been employed either for diagnosis or treatment of infections caused by different pathogens. Specifically for Shiga toxin-producing Escherichia coli (STEC), numerous immunoassays have been developed for STEC diagnosis, showing variability in sensitivity and specificity when evaluated by reference laboratories, and no therapy or vaccines are currently approved. Thus, the aim of this work was the characterization of the interaction between MAbs against Stx1 and Stx2 toxins and their neutralizing abilities to enable their use as tools for diagnosis and therapy. The selected clones designated 3E2 (anti-Stx1) and 2E11 (anti-Stx2) were classified as IgG1. 3E2 recognized the B subunit of Stx1 with an affinity constant of 2.5 × 10−10 M, detected as little as 6.2 ng of Stx1 and was stable up to 50 ºC. In contrast, 2E11 recognized the A subunit of Stx2, was stable up to 70 ºC, had a high dissociation constant of  6.1 × 10−10 M, and detected as little as 12.5 ng of Stx2. Neutralization tests showed that 160 ng of 3E2 MAb inhibited 80% of Stx1 activity and 500 µg 2E11 MAb were required for 60% inhibition of Stx2 activity. These MAb amounts reversed 25 to 80% of the cytotoxicity triggered by different STEC isolates. In conclusion, these MAbs show suitable characteristics for their use in STEC diagnosis and encourage future studies to investigate their protective efficacy.

AQUADock Mountain Lion 2.0 - Mountain Lion theme for Mac OS X 10.5.. (Free)

Posted: 18 Sep 2012 02:27 AM PDT



AQUADock Mountain Lion is a theme designed to give PowerPC users the look and feel of OS X 10.8.

Version 2.0: Release notes were unavailable when this listing was updated.

Mac OS X 10.5 only

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This posting includes an audio/video/photo media file: Download Now

teletext 2.0.9 - Widget displays teletext for various channels around the world.. (Free)

Posted: 18 Sep 2012 02:31 AM PDT



teletext displays pages of the following channels:
  • Austria: ORF
  • Belgium: één, RTBF
  • Germany: 3sat, ARD, BR, festival, hr, MDR, NDR, SR, WDR, Sat.1
  • Ireland: RTÉ Aertel
  • Italy: RAI
  • Netherlands: NOS, RTVNH, Noord, Oost
  • Portugal: RTP
  • Spain: TVE, Antena 3, TV3
  • Sweden: SVT, TV3, TV4
  • Switzerland: SF1, SF2, SFinfo, RTS un, RTS deux, RSI1, RSI2

Access a page by typing its number or by one of 9 shortcuts.
Navigate through pages with the left and right arrow keys, through sub pages with the up and down arrow keys.

Version 2.0.9:
  • Fix for some channels.


Mac OS X 10.4 or later

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