Games |
- Trickster Online - Videos and Trailers
- Pocket Gnome 1.6.1.0 - Bot for repetitive tasks in World of Warcraft.. (Commercial)
- Abuzzle 1.1.2 - Abstract puzzle game.. (Commercial)
- Nutrients, Vol. 4, Pages 1213-1218: Assessing the Relationship between Vitamin D3 and Stratum Corneum Hydration for the Treatment of Xerotic Skin
- Nutrients, Vol. 4, Pages 1187-1212: Exercise-Induced Immunodepression in Endurance Athletes and Nutritional Intervention with Carbohydrate, Protein and Fat — What Is Possible, What Is Not?
- IJMS, Vol. 13, Pages 10970-10985: Biocompatibility of Genipin and Glutaraldehyde Cross-Linked Chitosan Materials in the Anterior Chamber of the Eye
- Sensors, Vol. 12, Pages 12098-12109: Comparison of pH Data Measured with a pH Sensor Array Using Different Data Fusion Methods
- IJERPH, Vol. 9, Pages 3209-3226: Relationship between Heavy Metal Concentrations in Soils and Grasses of Roadside Farmland in Nepal
- IJERPH, Vol. 9, Pages 3197-3208: Artificial Cold Air Increases the Cardiovascular Risks in Spontaneously Hypertensive Rats
- Celebrating the Final Fantasy Hero Archetypes
- Valve recruiting for hardware industrial designer
- The OzSpot 04/09/12: Gaymercon, Metal Gear Solid Movie!
- From the sublime to the ridiculous – is this the worst official hardware downgrade ever?
- IJERPH, Vol. 9, Pages 3166-3196: Analysis of Endocrine Disrupting Pesticides by Capillary GC with Mass Spectrometric Detection
- Animals, Vol. 2, Pages 437-454: A Greenhouse Gas and Soil Carbon Model for Estimating the Carbon Footprint of Livestock Production in Canada
- DOTA 2 Diaries - Part 8: M-M-MEGA FAIL
- What's Up Weekly
- Animals, Vol. 2, Pages 426-436: Gold Bead Implantation in Acupoints for Coxofemoral Arthrosis in Dogs: Method Description and Adverse Effects
- Molecules, Vol. 17, Pages 10540-10549: Antibacterial and Antioxidant Potency of Floral Honeys from Different Botanical and Geographical Origins
- Adventures of Valentin: The Valiant Viking
| Trickster Online - Videos and Trailers Posted: 04 Sep 2012 02:44 AM PDT Trickster Online season 2 skill update trailer. |
| Pocket Gnome 1.6.1.0 - Bot for repetitive tasks in World of Warcraft.. (Commercial) Posted: 04 Sep 2012 03:07 AM PDT  Pocket Gnome is a "bot" for World of Warcraft. Its goal is to make it easier to automate repetitive activities within the game. Version 1.6.1.0:
Mac OS X 10.6 or later, World of Warcraft. Download Now This posting includes an audio/video/photo media file: Download Now |
| Abuzzle 1.1.2 - Abstract puzzle game.. (Commercial) Posted: 04 Sep 2012 02:58 AM PDT  Abuzzle is an abstract puzzle game: match the big board to the little one as quickly as possible. Click-and-drag to manipulate the patterns, and click to change the colors. Features:
Version 1.1.2:
This posting includes an audio/video/photo media file: Download Now |
| Posted: 04 Sep 2012 12:00 AM PDT Vitamin D3 has been called the "sunshine" vitamin since the formation of vitamin D is mediated by exposure to sunlight. Vitamin D3 is linked to many health benefits, however serum levels of vitamin D3 have been decreasing over the last few decades and the lower levels of vitamin D3 may have consequences on normal physiology. We investigated the association between serum 25-hydroxyvitamin D (25(OH)D) levels and stratum corneum conductance as well as the effect of topical application of cholecalciferol (vitamin D3) on dry skin. Eighty three subjects were recruited and blood serum levels and skin conductance measurements were taken after a one week washout. A correlation was observed between vitamin D levels and skin moisture content, individuals with lower levels of vitamin D had lower average skin moisture. Subsequently, a 3-week split leg, randomized, vehicle controlled clinical study was conducted on a subset of 61 of the above individuals who were identified with non-sufficient vitamin D serum levels. Topical supplementation with cholecalciferol significantly increased measurements of skin moisturization and resulted in improvements in subjective clinical grading of dry skin. Taken together our finding suggest a relationship between serum vitamin D3 (25(OH)D) levels and hydration of the stratum corneum and further demonstrate the skin moisture benefit from topical application of vitamin D3. |
| Posted: 04 Sep 2012 12:00 AM PDT Heavily exercising endurance athletes experience extreme physiologic stress, which is associated with temporary immunodepression and higher risk of infection, particularly upper respiratory tract infections (URTI). The aim of this review is to provide a critical up-to-date review of existing evidence on the immunomodulatory potential of selected macronutrients and to evaluate their efficacy. The results of 66 placebo-controlled and/or crossover trials were compared and analysed. Among macronutrients, the most effective approach to maintain immune function in athletes is to consume ≥6% carbohydrate during prolonged exercise. Because inadequate nutrition affects almost all aspects of the immune system, a well-balanced diet is also important. Evidence of beneficial effects from other macronutrients is scarce and results are often inconsistent. Using a single nutrient may not be as effective as a mixture of several nutritional supplements. Due to limited research evidence, with the exception of carbohydrate, no explicit recommendations to reduce post-exercise URTI symptoms with single macronutrients can be derived. |
| Posted: 04 Sep 2012 12:00 AM PDT Chitosan is a naturally occurring cationic polysaccharide and has attracted much attention in the past decade as an important ophthalmic biomaterial. We recently demonstrated that the genipin (GP) cross-linked chitosan is compatible with human retinal pigment epithelial cells. The present work aims to further investigate the in vivo biocompatibility of GP-treated chitosan (GP-chi group) by adopting the anterior chamber of a rabbit eye model. The glutaraldehyde (GTA) cross-linked samples (GTA-chi group) were used for comparison. The 7-mm-diameter membrane implants made from either non-cross-linked chitosan or chemically modified materials with a cross-linking degree of around 80% were inserted in the ocular anterior chamber for 24 weeks and characterized by slit-lamp and specular microscopic examinations, intraocular pressure measurements, and corneal thickness measurements. The interleukin-6 expressions at mRNA level were also detected by quantitative real-time reverse transcription polymerase chain reaction. Results of clinical observations showed that the overall ocular scores in the GTA-chi groups were relatively high. In contrast, the rabbits bearing GP-chi implants in the anterior chamber of the eye exhibited no signs of ocular inflammation. As compared to the non-cross-linked counterparts, the GP-chi samples improved the preservation of corneal endothelial cell density and possessed better anti-inflammatory activities, indicating the benefit action of the GP cross-linker. In summary, the intracameral tissue response to the chemically modified chitosan materials strongly depends on the selection of cross-linking agents. |
| Posted: 04 Sep 2012 12:00 AM PDT This paper introduces different data fusion methods which are used for an electrochemical measurement using a sensor array. In this study, we used ruthenium dioxide sensing membrane pH electrodes to form a sensor array. The sensor array was used for detecting the pH values of grape wine, generic cola drink and bottled base water. The measured pH data were used for data fusion methods to increase the reliability of the measured results, and we also compared the fusion results with other different data fusion methods. |
| Posted: 04 Sep 2012 12:00 AM PDT Transportation activities can contribute to accumulation of heavy metals in roadside soil and grass, which could potentially compromise public health and the environment if the roadways cross farmland areas. Particularly, heavy metals may enter the food chain as a result of their uptake by roadside edible grasses. This research was conducted to investigate heavy metal (Cu, Zn, Cd, and Pb) concentrations in roadside farmland soils and corresponding grasses around Kathmandu, Nepal. Four factors were considered for the experimental design, including sample type, sampling location, roadside distance, and tree protection. A total of 60 grass samples and 60 topsoil samples were collected under dry weather conditions. The Multivariate Analysis of Variance (MANOVA) results indicate that the concentrations of Cu, Zn, and Pb in the soil samples are significantly higher than those in the grass samples; the concentrations of Cu and Pb in the suburban roadside farmland are higher than those in the rural mountainous roadside farmland; and the concentrations of Cu and Zn at the sampling locations with roadside trees are significantly lower than those without tree protection. The analysis of transfer factor, which is calculated as the ratio of heavy-metal concentrations in grass to those in the corresponding soil, indicates that the uptake capabilities of heavy metals from soil to grass is in the order of Zn > Cu > Pb. Additionally, it is found that as the soils' heavy-metal concentrations increase, the capability of heavy-metal transfer to the grass decreases, and this relationship can be characterized by an exponential regression model. |
| Posted: 04 Sep 2012 12:00 AM PDT The purpose was to investigate the effects of artificial cold air on cardiovascular risk in hypertensive subjects. An artificial cold air was simulated with hourly ambient temperature data of a real moderate cold air in China. Twenty-four male SHR rats were randomly divided into the minimum temperature (Tmin) group, the rewarming temperature (Tr) group and two concurrent control groups with six rats in each (Tmin and Tr represent two cold air time points, respectively). Tmin and Tr groups were exposed to the cold air that was stopped at Tmin and Tr, respectively. After cold air exposure, blood pressure, heart rate and body weight were monitored, blood was collected for the detection of some indexes like fibrinogen, total cholesterol and uric acid. Results demonstrated that blood pressure, whole blood viscosity, blood fibrinogen, total cholesterol and uric acid increased significantly both in the Tmin and Tr groups; low density lipoprotein/high density lipoprotein increased significantly only in Tr group; there was higher level of blood fibrinogen in the Tr group than the Tmin group; higher levels of creatine kinase-MB was found in both the Tmin and Tr groups. These results suggest that cold air may increase the cardiovascular risks in hypertensive subjects indirectly through its effects on the sympathetic nervous system and renin angiotensin system, blood pressure and atherosclerosis risk factors like blood viscosity and fibrinogen, lipids and uric acid in the blood. |
| Celebrating the Final Fantasy Hero Archetypes Posted: 03 Sep 2012 11:40 PM PDT In lieu of the recent Final Fantasy 25th Anniversary celebration, GameSpot Asia's Jonathan Toyad brings up the most renowned character archetype of the series and explains why we love them so much. Read and Post Comments | Get the full article at GameSpot "Celebrating the Final Fantasy Hero Archetypes" was posted by edmondt on Mon, 03 Sep 2012 23:40:19 -0700 |
| Valve recruiting for hardware industrial designer Posted: 03 Sep 2012 11:04 PM PDT Job listing on the company's website hints at intention to expand into hardware market.
Valve has posted a job listing that is lending further credibility to rumours that the company will enter the hardware market. Posted on its website, the job description for an industrial designer described the company as being "traditionally a software company," but one who has become "frustrated by the lack of innovation in the computer hardware space."
Later in the listing, the company said that "Even basic input, the keyboard and mouse, haven't really changed in any meaningful way over the years." Earlier this year, Valve said that it was a "long way from shipping any sort of hardware," and that the boxes the firm had previously put together were for internal testing only. In a separate interview, Valve co-founder and managing director Gabe Newell responded to whether the company would ever consider a future in selling hardware. "Well, if we have to sell hardware, we will. We have no reason to believe we're any good at it; it's more we think that we need to continue to have innovation. And if the only way to get these kind of projects started is by us going and developing and selling the hardware directly, then that's what we'll do," said Newell. Despite numerous rumours and speculation, to date, Valve has made no official announcements that it is working to produce a gaming device. Read and Post Comments | Get the full article at GameSpot "Valve recruiting for hardware industrial designer" was posted by Zorine Te on Mon, 03 Sep 2012 23:04:01 -0700 |
| The OzSpot 04/09/12: Gaymercon, Metal Gear Solid Movie! Posted: 03 Sep 2012 07:56 PM PDT On this week's show we look at Microsoft's support of Gaymercon, the newly announced Metal Gear Solid movie, Batlle.net banned in Iran and more! Get the full article at GameSpot "The OzSpot 04/09/12: Gaymercon, Metal Gear Solid Movie!" was posted by Zorine Te on Mon, 03 Sep 2012 19:56:20 -0700 |
| From the sublime to the ridiculous – is this the worst official hardware downgrade ever? Posted: 04 Sep 2012 01:57 AM PDT I like racing games. In fact, I've personally spent a lot of money on making the experience of playing a racing game as close to the real thing as my |
| Posted: 04 Sep 2012 12:00 AM PDT Endocrine disrupting chemicals, among them many pesticides, alter the normal functioning of the endocrine system of both wildlife and humans at very low concentration levels. Therefore, the importance of method development for their analysis in food and the environment is increasing. This also covers contributions in the field of ultra-trace analysis of multicomponent mixtures of organic pollutants in complex matrices. With this fact conventional capillary gas chromatography (CGC) and fast CGC with mass spectrometric detection (MS) has acquired a real importance in the analysis of endocrine disrupting pesticide (EDP) residues. This paper provides an overview of GC methods, including sample preparation steps, for analysis of EDPs in a variety of matrices at ultra-trace concentration levels. Emphasis is put on separation method, mode of MS detection and ionization and obtained limits of detection and quantification. Analysis time is one of the most important aspects that should be considered in the choice of analytical methods for routine analysis. Therefore, the benefits of developed fast GC methods are important. |
| Posted: 04 Sep 2012 12:00 AM PDT To assess tradeoffs between environmental sustainability and changes in food production on agricultural land in Canada the Unified Livestock Industry and Crop Emissions Estimation System (ULICEES) was developed. It incorporates four livestock specific GHG assessments in a single model. To demonstrate the application of ULICEES, 10% of beef cattle protein production was assumed to be displaced with an equivalent amount of pork protein. Without accounting for the loss of soil carbon, this 10% shift reduced GHG emissions by 2.5 TgCO2e y−1. The payback period was defined as the number of years required for a GHG reduction to equal soil carbon lost from the associated land use shift. A payback period that is shorter than 40 years represents a net long term decrease in GHG emissions. Displacing beef cattle with hogs resulted in a surplus area of forage. When this residual land was left in ungrazed perennial forage, the payback periods were less than 4 years and when it was reseeded to annual crops, they were equal to or less than 40 years. They were generally greater than 40 years when this land was used to raise cattle. Agricultural GHG mitigation policies will inevitably involve a trade-off between production, land use and GHG emission reduction. ULICEES is a model that can objectively assess these trade-offs for Canadian agriculture. |
| DOTA 2 Diaries - Part 8: M-M-MEGA FAIL Posted: 03 Sep 2012 08:17 PM PDT As we migrate to a more US-friendly time, the GameSpot community shows us just how far we really have to go with our DOTA 2 skills.
Read and Post Comments | Get the full article at GameSpot "DOTA 2 Diaries - Part 8: M-M-MEGA FAIL" was posted by edmondt on Mon, 03 Sep 2012 20:17:30 -0700 |
| Posted: 03 Sep 2012 11:47 PM PDT Now that the only three-day weekend of the semester is over, it's time to get serious about classes. This posting includes an audio/video/photo media file: Download Now |
| Posted: 04 Sep 2012 12:00 AM PDT Gold bead implantation has been used for years as an alternative method to improve function in chronic joint disease both in humans and dogs. The aims of the present study were to describe the technique of implanting 24-karat gold beads around the hip joints of dogs with chronic hip dysplasia, and to record any side effects or complications of such treatment. A prospective placebo-controlled double-blinded clinical trial was performed. Eighty dogs were randomly allocated to treatment or placebo, with 38 in the gold implantation group and 42 in the placebo group, and followed intensely for six months. The implantation technique was simple to perform, using fluoroscopy and with the dogs under inhalation anesthesia for about 30 minutes. Adverse effects, measured as pain or discomfort, were seen for a period of up to four weeks in 15 of the dogs in the gold implantation group, compared to six dogs in the placebo group. During implantation, a technical difficulty occurred as 82% of the dogs showed leakage of blood and/or synovia from the needles. The dogs in the gold implantation group were radiographed 18 months later. Of the 30 dogs that were radiographed at both inclusion and 24 months, 80% (24 dogs) showed a deterioration of the coxofemoral arthrosis, the other six had stable disease evaluated by radiography. Migration of gold beads was only observed in one dog. |
| Posted: 04 Sep 2012 12:00 AM PDT In order to assess their physicochemical and antioxidant properties as well as their antimicrobial potency, four varieties of honey from different botanical and geographical origins were used. The agar incorporation method was used to determine the antimicrobial potency of honeys. The total phenol content was determined by a modified Folin–Ciocalteu method and the free radical scavenging activity by the Fe3+ reducing power (FRAP) assay. Manuka honey was the most effective against Staphylococcus aureus Oxa R and S. aureus Oxa S with a Minimum Inhibitory Concentration (MIC) of 6% and 7%, respectively, whereas wild carrot honey was the most effective against Pseudomonas aeruginosa, with a MIC of 12%. Lavender honey was the least effective against all tested strains, even though was found to have the lowest pH and water content. Manuka honey had the highest content of polyphenols, with 899.09 ± 11.75 mg gallic acid/kg, whereas lavender honey had the lowest, with 111.42 ± 3.54 mg gallic acid/kg. A very significant correlation (r value was 0.9079 at P < 0.05) was observed between the total polyphenolic content and the Fe2+ content formed in the presence of the honey antioxidants. The differences between honey samples in terms of antibacterial and antioxidant activity could be attributed to the natural variations in floral sources of nectar and the different locations. |
| Adventures of Valentin: The Valiant Viking Posted: 03 Sep 2012 11:38 PM PDT Platform: iOS, Flash —  Valentin isn't what you would call the bravest Viking in the village. His best ability of running in fear is a better asset for the hundred meter dash than a battle with some big old brutes. However, he has to prove himself somehow and taking on the evil wizard who kidnapped Princess Estelle is the perfect way to do so. Armed with only his wits, guide Valentin through thirteen scenes of point and click adventure and brave the terrible wizard! Tagged as: browser, flash, free, game, ios, ipad, iphone, linux, mac, mobile, playtinumgames, pointandclick, puzzle, rating-g, tablet, windows |
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