Games |
- NewsBar 2.6 - Fast-updating Desktop RSS News Reader.. (Commercial)
- NewsBar Lite 2.6 - Fast-updating RSS News Reader (lite version).. (Free)
- Injustice: Gods Among Us TGS 2012 video demo - See Superman tear apart Flash
- Project X Zone TGS 2012 preview - Why we need this crazy crossover
- IJMS, Vol. 13, Pages 12046-12061: Genetic Diversity Characterization of Porcine Reproductive and Respiratory Syndrome Virus Isolates in Romania, Based on Phylogenetic Analysis
- Future Internet, Vol. 4, Pages 852-864: When the Social Meets the Semantic: Social Semantic Web or Web 2.5
- Viruses, Vol. 4, Pages 1687-1710: Emerging Themes from EBV and KSHV microRNA Targets
- Train Simulator 2013 - Screenshots
- Dark Parables: The Red Riding Hood Sisters
- Viruses, Vol. 4, Pages 1668-1686: Clinical Management of Filovirus-Infected Patients
- Viruses, Vol. 4, Pages 1651-1667: Uncovering Viral Protein-Protein Interactions and their Role in Arenavirus Life Cycle
- Viruses, Vol. 4, Pages 1619-1650: Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
- Robbie Williams loves board games
- Sensors, Vol. 12, Pages 12844-12869: A Real-Time Cardiac Arrhythmia Classification System with Wearable Sensor Networks
- Masa vs aLive Game 1 NASL Season 4 W2D1
- GT5 update and DLC detailed
- Razer Joystick Prototype
- Molecules, Vol. 17, Pages 11292-11293: Hasegawa, T., et al. Structure-Odor Relationships of αSantalol Derivatives with Modified Side Chains. Molecules, 2012, 17, 2259-2270
- Molecules, Vol. 17, Pages 11281-11291: In Vitro Antioxidant Properties of Flavonoids and Polysaccharides Extract from Tobacco (Nicotiana tabacum L.) Leaves
- Molecules, Vol. 17, Pages 11269-11280: Association of KIF6 Variant with Lipid Level and Angiographic Coronary Artery Disease Events Risk in the Han Chinese Population
| NewsBar 2.6 - Fast-updating Desktop RSS News Reader.. (Commercial) Posted: 21 Sep 2012 03:24 AM PDT  NewsBar is built with a fresh concept: news feeds delivered with a smooth animation, right to your desktop. All of your RSS feeds continuously appear on the selected side of your display, or in a regular window. NewsBar is like having your own, personal news agency. You don't have to waste your time checking webpages - NewsBar will show you what's going on. No delays, no waiting: stories appear right on your display, just as they are published. You can easily Read, Follow, Mark, Filter, and Search news from your favorite feeds. Stories are read directly from RSS sources without delay, with the ability to check for new items as often as every minute. "If you're looking for something a bit different in your RSS reader, I really recommend giving NewsBar a try, it's a surprisingly powerful and enjoyable little app." - Mac Appstorm Features:
Version 2.6:
Mac OS X 10.6.6 or later Download Now |
| NewsBar Lite 2.6 - Fast-updating RSS News Reader (lite version).. (Free) Posted: 21 Sep 2012 03:33 AM PDT  NewsBar is built with a fresh concept: news feeds delivered with a smooth animation, right to your desktop. All of your RSS feeds continuously appear on the selected side of your display, or in a regular window. NewsBar is like having your own, personal news agency. You don't have to waste your time checking webpages - NewsBar will show you what's going on. No delays, no waiting: stories appear right on your display, just as they are published. You can easily Read, Follow, Mark, Filter, and Search news from your favorite feeds. Stories are read directly from RSS sources without delay, with the ability to check for new items as often as every minute. "If you're looking for something a bit different in your RSS reader, I really recommend giving NewsBar a try, it's a surprisingly powerful and enjoyable little app." - Mac Appstorm Features:
Mac OS X 10.6.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Injustice: Gods Among Us TGS 2012 video demo - See Superman tear apart Flash Posted: 21 Sep 2012 03:38 AM PDT Though Tokyo Game Show normally highlights games of Japanese origin, more and more international releases are making waves at the event. For example, this |
| Project X Zone TGS 2012 preview - Why we need this crazy crossover Posted: 21 Sep 2012 03:38 AM PDT One of the craziest video game crossovers, Namco x Capcom for the PS2, never made it to our shores--and that's a darn shame. This grid-style, turn-based |
| Posted: 21 Sep 2012 12:00 AM PDT Porcine reproductive and respiratory syndrome (PRRS) is a disease produced by the (PRRS) virus, characterized by endemic evolution in the majority of countries, which remains in actuality being a permanent threat to health and economic free farms, as well as for those infected. The aim of this study was to evaluate the genetic diversity of Romanian PRRSV isolates from the four most important pig farms in Romania by comparing the nucleotide sequences obtained for ORF5 and ORF7 with a wide range of sequences from GenBank belonging to the main types of PRRSV; the type 1. Eighteen different sequences were obtained for ORF5 gene and 10 for ORF7 gene. One Romanian isolate (Rom3) was found in three of the four different investigated farms. The phylogenetic analysis revealed that the Romanian PRRSV nucleotide sequences clustered in three groups within the subtype 1 of the virus. The analysis of amino acid sequences evidenced for GP5 and N-nucleocapsid proteins confirmed that the Romanian virus belonged to type 1. |
| Posted: 21 Sep 2012 12:00 AM PDT The social trend is progressively becoming the key feature of current Web understanding (Web 2.0). This trend appears irrepressible as millions of users, directly or indirectly connected through social networks, are able to share and exchange any kind of content, information, feeling or experience. Social interactions radically changed the user approach. Furthermore, the socialization of content around social objects provides new unexplored commercial marketplaces and business opportunities. On the other hand, the progressive evolution of the web towards the Semantic Web (or Web 3.0) provides a formal representation of knowledge based on the meaning of data. When the social meets semantics, the social intelligence can be formed in the context of a semantic environment in which user and community profiles as well as any kind of interaction is semantically represented (Semantic Social Web). This paper first provides a conceptual analysis of the second and third version of the Web model. That discussion is aimed at the definition of a middle concept (Web 2.5) resulting in the convergence and integration of key features from the current and next generation Web. The Semantic Social Web (Web 2.5) has a clear theoretical meaning, understood as the bridge between the overused Web 2.0 and the not yet mature Semantic Web (Web 3.0). |
| Viruses, Vol. 4, Pages 1687-1710: Emerging Themes from EBV and KSHV microRNA Targets Posted: 20 Sep 2012 12:00 AM PDT EBV and KSHV are both gamma-herpesviruses which express multiple viral microRNAs. Various methods have been used to investigate the functions of these microRNAs, largely through identification of microRNA target genes. Surprisingly, these related viruses do not share significant sequence homology in their microRNAs. A number of reports have described functions of EBV and KSHV microRNA targets, however only three experimentally validated target genes have been shown to be targeted by microRNAs from both viruses. More sensitive methods to identify microRNA targets have predicted approximately 60% of host targets could be shared by EBV and KSHV microRNAs, but by targeting different sequences in the host targets. In this review, we explore the similarities of microRNA functions and targets of these related viruses. |
| Train Simulator 2013 - Screenshots Posted: 21 Sep 2012 03:30 AM PDT Packed full of technical innovations, Train Simulator 2013 lets you drive trains, build worlds and add to your collection. With hours of driving challenges to enjoy on routes from around the world and superb locomotives from the golden age of steam to the modern era, Train Simulator 2013 is the first choice for simulation fans around the world! |
| Dark Parables: The Red Riding Hood Sisters Posted: 20 Sep 2012 05:50 PM PDT Platform: Mac, Windows —  In this fourth installment of Blue Tea Games' darkly dramatic adventure hybrid series, you join a band of femme fatales, once victims in other fairytales, to fight against a power-warped villainess and her plague of mist wolves. Fragmented object search scenes, side quests for cursed items, and a nice offering of gently-challenging puzzles add to your immersion in this action-filled, and oft times violent, adventure. Tagged as: adventure, affiliate, blueteagames, casual, collectorsedition, darkparables, demo, download, fantasy, game, hiddenobject, hybrid, mac, pointandclick, puzzle, rating-y, windows |
| Viruses, Vol. 4, Pages 1668-1686: Clinical Management of Filovirus-Infected Patients Posted: 20 Sep 2012 12:00 AM PDT Filovirus infection presents many unique challenges to patient management. Currently no approved treatments are available, and the recommendations for supportive care are not evidence based. The austere clinical settings in which patients often present and the sporadic and at times explosive nature of filovirus outbreaks have effectively limited the information available to evaluate potential management strategies. This review will summarize the management approaches used in filovirus outbreaks and provide recommendations for collecting the information necessary for evaluating and potentially improving patient outcomes in the future. |
| Posted: 20 Sep 2012 12:00 AM PDT The Arenaviridae family includes widely distributed pathogens that cause severe hemorrhagic fever in humans. Replication and packaging of their single-stranded RNA genome involve RNA recognition by viral proteins and a number of key protein-protein interactions. Viral RNA synthesis is directed by the virus-encoded RNA dependent-RNA polymerase (L protein) and requires viral RNA encapsidation by the Nucleoprotein. In addition to the role that the interaction between L and the Nucleoprotein may have in the replication process, polymerase activity appears to be modulated by the association between L and the small multifunctional Z protein. Z is also a structural component of the virions that plays an essential role in viral morphogenesis. Indeed, interaction of the Z protein with the Nucleoprotein is critical for genome packaging. Furthermore, current evidence suggests that binding between Z and the viral envelope glycoprotein complex is required for virion infectivity, and that Z homo-oligomerization is an essential step for particle assembly and budding. Efforts to understand the molecular basis of arenavirus life cycle have revealed important details on these viral protein-protein interactions that will be reviewed in this article. |
| Posted: 20 Sep 2012 12:00 AM PDT Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral infection, there remain no sanctioned therapeutic or vaccine strategies. Current progress in the development of filovirus therapeutics and vaccines is outlined herein with respect to their current level of testing, evaluation, and proximity toward human implementation, specifically with regard to human clinical trials, nonhuman primate studies, small animal studies, and in vitro development. Contemporary methods of supportive care and previous treatment approaches for human patients are also discussed. |
| Robbie Williams loves board games Posted: 21 Sep 2012 01:39 AM PDT The 'Candy' singer - who has previously battled drug addiction - admits his life is much quieter these days and he is excited about taking his new baby daughter, Theodora Rose, toy shopping. This posting includes an audio/video/photo media file: Download Now |
| Posted: 21 Sep 2012 12:00 AM PDT Long term continuous monitoring of electrocardiogram (ECG) in a free living environment provides valuable information for prevention on the heart attack and other high risk diseases. This paper presents the design of a real-time wearable ECG monitoring system with associated cardiac arrhythmia classification algorithms. One of the striking advantages is that ECG analog front-end and on-node digital processing are designed to remove most of the noise and bias. In addition, the wearable sensor node is able to monitor the patient's ECG and motion signal in an unobstructive way. To realize the real-time medical analysis, the ECG is digitalized and transmitted to a smart phone via Bluetooth. On the smart phone, the ECG waveform is visualized and a novel layered hidden Markov model is seamlessly integrated to classify multiple cardiac arrhythmias in real time. Experimental results demonstrate that the clean and reliable ECG waveform can be captured in multiple stressed conditions and the real-time classification on cardiac arrhythmia is competent to other workbenches. |
| Masa vs aLive Game 1 NASL Season 4 W2D1 Posted: 20 Sep 2012 09:59 PM PDT Game 1 of Masa vs aLive at the NASL Season 4 week 2 division 1.
Read and Post Comments | Get the full article at GameSpot "Masa vs aLive Game 1 NASL Season 4 W2D1" was posted by erickt on Thu, 20 Sep 2012 21:59:29 -0700 |
| Posted: 20 Sep 2012 07:39 PM PDT Latest Gran Turismo 5 DLC offers three new cars; the update will add game enhancements and fix some reported issues.
Sony has unveiled new DLC and an update for Gran Turismo 5 on its official PlayStation blog. Due to arrive on September 25, the DLC features three new cars available for individual purchase at A$0.99 each.
The new cars available include the Nissan GT-R N4 GT Academy '12, Subaru BRZ S'12, and Honda Weider HSV-010 (Super GT) '11. In addition to new content, a downloadable update will bring the game to version 2.08, and add tweaks including the option to disable collisions in online races, and change the rate of tire wear and air resistance. Patch notes include: ' Now possible to select "disable collisions" in the [Event Settings] of online races GT5 was well received when it was released in 2010 as a PlayStation 3 exclusive, and has sold over 6 million copies. Read and Post Comments | Get the full article at GameSpot "GT5 update and DLC detailed" was posted by Zorine Te on Thu, 20 Sep 2012 19:39:41 -0700 |
| Posted: 20 Sep 2012 07:12 PM PDT We check out the highly customizable prototype for Razer's upcoming joystick. Read and Post Comments | Get the full article at GameSpot "Razer Joystick Prototype" was posted by Jan on Thu, 20 Sep 2012 19:12:34 -0700 |
| Posted: 21 Sep 2012 12:00 AM PDT The authors are sorry to report that some of the 13C-NMR data reported in their recently published paper [1] were incorrect. While this manuscript was in preparation and pending recording of some 13C-NMR spectra the data of α-santalol was used as a placeholder. Upon revising the manuscript according to the reviewers' comments, they mistakenly thought that all spectral data had been replaced by the correct measured data. Consequently the authors wish to make at this time the following corrections to the paper. |
| Posted: 21 Sep 2012 12:00 AM PDT In the present study, antioxidant properties of flavonoids and polysaccharides from tobacco (Nicotiana tabacum L.) leaves were evaluated in several in vitro systems, e.g., scavenging activities on hydroxyl, superoxide anion, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radicals, and reducing power. Flavonoids showed much better activity than polysaccharides in scavenging activities on free radicals. When compared to the positive control, ascorbic acid, both showed weaker antioxidant potential. However, flavonoids possessed comparable superoxide anion, DPPH and ABTS radical scavenging abilities to ascorbic acid at high concentration (600 μg/mL). Meanwhile, it was found that flavonoids had prominent effects on the reducing power, which was equivalent to ascorbic acid, and was significantly higher than polysaccharides. These results clearly indicate that flavonoids are effective in scavenging free radicals and have the potential to be powerful antioxidants. Thus, tobacco leaves could be considered as a potential source of natural antioxidants for food, pharmaceutical, cosmetics or nutraceutical industries. |
| Posted: 21 Sep 2012 12:00 AM PDT KIF6 is a class of molecular motor from the kinesin superfamily. Recently, multiple large studies consisting mainly of Europeans have shown that KIF6 Trp719Arg SNP may be a new predictive factor for coronary artery disease (CAD) event risk. The allelic frequency distribution of rs20455 is different in various populations, yet studies among the Han population, one of the largest ethnic groups in the World, have not been conducted. This study is aimed to evaluate the association of KIF6 Trp719Arg variant with angiographic CAD and serum lipid levels in the Han population from northern China. In this case-controlled study, peripheral blood samples were collected from 356 patients and 568 controls of Han Chinese origin. Genotyping was performed by a high-resolution melting curve. The impact of rs20455 on CAD and non-fatal MI was evaluated in a dominant genetic model with stepwise multiple regression analysis. There were no significant differences of genotypes and allele frequency between angiographic CAD and control groups (p > 0.05); however, that of MI and non-MI subgroups were significant differences (p < 0.05). After adjusting for significant risk factors, angiographic CAD risk was not significantly increased in 719Arg allele carriers compared with non-carriers. Further analysis revealed that the non-fatal MI risk and triglyceride levels were significantly higher in 719Arg allele carriers than non-carriers. In conclusion, KIF6 719Arg allele was not an independent risk factor for angiographic CAD susceptibility in Han populations from northern China. However, it was associated with a significantly higher TG level, which may indicate an increased myocardial infarction risk in angiographic CAD patients. |
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