Games |
- cliclick 2.1 - Automate tasks by emulating mouse clicks.. (Free)
- When Vice Was King in El Cerrito
- Camping Manager - Screenshots
- Wargame: AirLand Battle - Screenshots
- Folder Icon Changer 3.0.7 - Create custom icons for your Mac.. (Shareware)
- Call of Duty: Black Ops II Zombies info imminent, two undead screens feed the tease
- Sensors, Vol. 12, Pages 13088-13108: On Increasing Network Lifetime in Body Area Networks Using Global Routing with Energy Consumption Balancing
- Panic Flight - Screenshots
- Sensors, Vol. 12, Pages 13075-13087: Electromagnetically-Actuated Reciprocating Pump for High-Flow-Rate Microfluidic Applications
- Sensors, Vol. 12, Pages 13058-13074: Yeast Sensors for Novel Drugs: Chloroquine and Others Revealed
- Sensors, Vol. 12, Pages 13034-13057: Expanding Window Compressed Sensing for Non-Uniform Compressible Signals
- Sensors, Vol. 12, Pages 13019-13033: Cu2O and Au/Cu2O Particles: Surface Properties and Applications in Glucose Sensing
- Film review: Killing Them Softly
- Sensors, Vol. 12, Pages 13002-13018: The Detection of Patients at Risk of Gastrointestinal Toxicity during Pelvic Radiotherapy by Electronic Nose and FAIMS: A Pilot Study
- Molecules, Vol. 17, Pages 11391-11420: Recent Updates in Redox Regulation and Free Radical Scavenging Effects by Herbal Products in Experimental Models of Parkinson’s Disease
- Torchlight II - Level 100 Berserker Veteran
- IJERPH, Vol. 9, Pages 3398-3420: Prenatal Secondhand Smoke Exposure and Infant Birth Weight in China
- Nutrients, Vol. 4, Pages 1358-1366: Preresection Obesity Increases the Risk of Hepatobiliary Complications in Short Bowel Syndrome
- Toxins, Vol. 4, Pages 768-777: Antibody to Heat Shock Protein 70 (HSP70) Inhibits Human T-Cell Lymphoptropic Virus Type I (HTLV-I) Production by Transformed Rabbit T-Cell Lines
- Community Q&A - Hitman: Absolution Interview
| cliclick 2.1 - Automate tasks by emulating mouse clicks.. (Free) Posted: 26 Sep 2012 02:52 AM PDT Cliclick is short for "Command-Line Interface Click". It is a a tiny shell / Terminal application that will emulate mouse and/or keyboard events. Hence, it is a tool for automating/scripting things that cannot otherwise be scripted (for instance, using AppleScript). Other than GUI Scripting, it does not require "Access for assistive devices" to be activated in the System Preferences.
Mac OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| When Vice Was King in El Cerrito Posted: 26 Sep 2012 02:28 AM PDT Does the name "Black Jack" Jerome ring a bell? It's a name that still sends shivers through the collective memory of El Cerrito. This posting includes an audio/video/photo media file: Download Now |
| Posted: 26 Sep 2012 03:22 AM PDT Hire employees such as cleaners and gardeners to keep your park in impeccable condition! As the money starts to roll in, you'll need to purchase better accommodation, decorate the camp site and purchase entertainment to keep your visitors happy. Features - Over 50 different 3d objects that can be placed in your camp site! - Keep residents happy as they interact with objects such as river hire and playgrounds! - Plant trees and decorations to keep ambience levels high! - Take on the challenge of different missions or put your skills to the test in endless mode! |
| Wargame: AirLand Battle - Screenshots Posted: 26 Sep 2012 03:18 AM PDT Wargame: AirLand Battle is making a huge leap forward with its visuals, bringing a level of detail never before seen in a real-time strategy game. Flat relief and lack of variety is now a thing of the past, as the new version of the IRISZOOM EngineTM displays spectacular graphics, with a huge variety of units, scenery and impressive topography reproduced from satellite maps. Command all the military resources of the Cold War era, from tanks to planes which make an outstanding entrance in the series! A total of 150 planes strengthen the playable arsenal of the game, from fighters to bombers to electronic warfare planes. Four new nations and their vehicles join the original eight from the first game, making a total of over 750 vehicles and combat units rendered in realistic detail with new textures! In Wargame: AirLand Battle, realism is also strengthened thanks to a new weapons system, better handling of fire and its effects, and a new Urban Combat Interface (UCI) allowing for battle inside cities block by block to take them over. The solo part of the game is composed of several new dynamic campaigns, during which you will manage all aspects of the battle. Lead each squad of the Theatre of Operation, and make good use of your reinforcements and strategic support. Each decision you make has an impact on the tactical outcome of battles, and also impacts the evolution of the global conflict! Wargame: AirLand Battle still allows you to customize your own army in solo and multiplayer modes, thanks to the 'Deck' system, which is now being enhanced with an integrated 'viewer'. |
| Folder Icon Changer 3.0.7 - Create custom icons for your Mac.. (Shareware) Posted: 26 Sep 2012 02:33 AM PDT  FolderIconCreator is an app to customize the icons on your Mac. The program comes pre-bundled with hundreds of icons that you can use to create custom folder icons and custom file icons on your Mac. Not only are their hundreds of icons included with the program, but you can create a library using ANY .png images, and convert them to icons easily using this program. You can make custom, personalized icons simply by using an image or photograph that you have (or downloaded from the internet), and dragging it into your custom icon library!You can assign custom icons in batches, or one at a time using drag-and-drop.The Folder Icon Maker comes pre-bundled with hundreds of icons, and we frequently release updates with additional icons. All updates are free forever! Version 3.0.7:
Mac OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Call of Duty: Black Ops II Zombies info imminent, two undead screens feed the tease Posted: 26 Sep 2012 02:46 AM PDT Two Call of Duty: Black Ops II Zombies screenshots have appeared ahead of today's full Zombies reveal (which was teased last week). Here they are:We'll |
| Posted: 26 Sep 2012 12:00 AM PDT Global routing protocols in wireless body area networks are considered. Global routing is augmented with a novel link cost function designed to balance energy consumption across the network. The result is a substantial increase in network lifetime at the expense of a marginal increase in energy per bit. Network maintenance requirements are reduced as well, since balancing energy consumption means all batteries need to be serviced at the same time and less frequently. The proposed routing protocol is evaluated using a hardware experimental setup comprising multiple nodes and an access point. The setup is used to assess network architectures, including an on-body access point and an off-body access point with varying number of antennas. Real-time experiments are conducted in indoor environments to assess performance gains. In addition, the setup is used to record channel attenuation data which are then processed in extensive computer simulations providing insight on the effect of protocol parameters on performance. Results demonstrate efficient balancing of energy consumption across all nodes, an average increase of up to 40% in network lifetime corresponding to a modest average increase of 0.4 dB in energy per bit, and a cutoff effect on required transmission power to achieve reliable connectivity. |
| Posted: 26 Sep 2012 03:11 AM PDT You can choose and upgrade the 10 available planes to fly at your convenience. You can also travel the globe in solo mode on 21 missions of increasing length, or demonstrate your flying skills to the world with the infinite flight. |
| Posted: 26 Sep 2012 12:00 AM PDT This study presents an electromagnetically-actuated reciprocating pump for high-flow-rate microfluidic applications. The pump comprises four major components, namely a lower glass plate containing a copper microcoil, a middle PMMA plate incorporating a PDMS diaphragm with a surface-mounted magnet, upper PMMA channel plates, and a ball-type check valve located at the channel inlet. When an AC current is passed through the microcoil, an alternating electromagnetic force is established between the coil and the magnet. The resulting bi-directional deflection of the PDMS diaphragm causes the check-valve to open and close; thereby creating a pumping effect. The experimental results show that a coil input current of 0.4 A generates an electromagnetic force of 47 mN and a diaphragm deflection of 108 μm. Given an actuating voltage of 3 V and a driving frequency of 15 Hz, the flow rate is found to be 13.2 mL/min under zero head pressure conditions. |
| Sensors, Vol. 12, Pages 13058-13074: Yeast Sensors for Novel Drugs: Chloroquine and Others Revealed Posted: 26 Sep 2012 12:00 AM PDT In this study the mitochondrion is regarded as a target to reveal compounds that may be used to combat various diseases. Consequently, the sexual structures of yeasts (with high mitochondrial activity) were identified as sensors to screen for various anti-mitochondrial drugs that may be toxic to humans and that are directed, amongst others, against fungal diseases and cancer. Strikingly, these sensors indicated that chloroquine is a potent pro-mitochondrial drug which stimulated yeast sexual reproduction. In addition, these sensors also showed that some Non-Steroidal Anti-Inflammatory drugs (NSAIDs), anti-malarial drugs, antifungal and anticancer drugs are anti-mitochondrial. These yeast sensor bio-assays may fast track studies aimed at discovering new drugs as well as their mechanisms and should now be further evaluated for selectivity towards anti-/ pro-mitochondrials, fertility drugs and contraceptives, using in vitro, in vivo, in silico and omics research. |
| Posted: 26 Sep 2012 12:00 AM PDT Many practical compressible signals like image signals or the networked data in wireless sensor networks have non-uniform support distribution in their sparse representation domain. Utilizing this prior information, a novel compressed sensing (CS) scheme with unequal protection capability is proposed in this paper by introducing a windowing strategy called expanding window compressed sensing (EW-CS). According to the importance of different parts of the signal, the signal is divided into several nested subsets, i.e., the expanding windows. Each window generates its own measurements using a random sensing matrix. The more significant elements are contained by more windows, so they are captured by more measurements. This design makes the EW-CS scheme have more convenient implementation and better overall recovery quality for non-uniform compressible signals than ordinary CS schemes. These advantages are theoretically analyzed and experimentally confirmed. Moreover, the EW-CS scheme is applied to the compressed acquisition of image signals and networked data where it also has superior performance than ordinary CS and the existing unequal protection CS schemes. |
| Posted: 26 Sep 2012 12:00 AM PDT In this work we investigated the surface and facet-dependent catalytic properties of metal oxide particles as well as noble metal/metal oxide heterogeneous structures, with cuprous oxide (Cu2O) and Au/Cu2O being selected as model systems. As an example of application, we explored the potential of these materials in developing electrocatalytic devices. Cu2O particles were synthesized in various shapes, then used for testing their morphology-dependent electrochemical properties applied to the detection of glucose. While we did not attempt to obtain the best detection limit reported to date, the octahedral and hexapod Cu2O particles showed reasonable detection limits of 0.51 and 0.60 mM, respectively, which are physiologically relevant concentrations. However, detection limit seems to be less affected by particle shapes than sensitivity. Heterogeneous systems where Au NPs were deposited on the surface of Cu2O particles were also tested with similar results in terms of the effect of surface orientation. |
| Film review: Killing Them Softly Posted: 26 Sep 2012 01:31 AM PDT It's been 12 years since Andrew Dominik exploded onto the scene with brutal Aussie crime drama Chopper. This posting includes an audio/video/photo media file: Download Now |
| Posted: 26 Sep 2012 12:00 AM PDT It is well known that the electronic nose can be used to identify differences between human health and disease for a range of disorders. We present a pilot study to investigate if the electronic nose and a newer technology, FAIMS (Field Asymmetric Ion Mobility Spectrometry), can be used to identify and help inform the treatment pathway for patients receiving pelvic radiotherapy, which frequently causes gastrointestinal side-effects, severe in some. From a larger group, 23 radiotherapy patients were selected where half had the highest levels of toxicity and the others the lowest. Stool samples were obtained before and four weeks after radiotherapy and the volatiles and gases emitted analysed by both methods; these chemicals are products of fermentation caused by gut microflora. Principal component analysis of the electronic nose data and wavelet transform followed by Fisher discriminant analysis of FAIMS data indicated that it was possible to separate patients after treatment by their toxicity levels. More interestingly, differences were also identified in their pre-treatment samples. We believe these patterns arise from differences in gut microflora where some combinations of bacteria result to give this olfactory signature. In the future our approach may result in a technique that will help identify patients at "high risk" even before radiation treatment is started. |
| Posted: 26 Sep 2012 12:00 AM PDT Parkinson's disease (PD) is a complex multifactorial disease marked by extensive neuropathology in the brain with selective yet prominent and progressive loss of mid-brain dopaminergic neurons. The etiological factors involved in the development of PD are still elusive, but oxidative stress arising when reactive oxygen species (ROS) exceed amounts required for normal redox signaling is considered one of the major factors. ROS cause oxidative damage to proteins, lipids, and DNA and are one of the most prominent factors related to neurodegeneration. Pre-clinical and clinical studies clearly demonstrate the effectiveness of oxidative stress in the pathogenesis of PD. Therefore, regulation of redox signaling and inhibiting excess ROS would contribute greatly not only to extend longevity but also to ameliorate the progression of dopaminergic cell death seen in patients with PD. Several herbal products are beneficial for maintaining nerve cell function and for treating various neurodegenerative disorders by reducing oxidative stress. Here, we summarize the recent knowledge concerning promising herbs that have shown significant beneficial effects based on regulation of redox status and ROS inhibition in toxin-induced PD models. |
| Torchlight II - Level 100 Berserker Veteran Posted: 25 Sep 2012 08:25 PM PDT Erick shows off the Torchlight II endgame with his Level 100 Berserker on Vertan difficulty.
Read and Post Comments | Get the full article at GameSpot "Torchlight II - Level 100 Berserker Veteran" was posted by DanM on Tue, 25 Sep 2012 20:25:05 -0700 |
| IJERPH, Vol. 9, Pages 3398-3420: Prenatal Secondhand Smoke Exposure and Infant Birth Weight in China Posted: 26 Sep 2012 12:00 AM PDT Epidemiologic evidence provides some support for a causal association between maternal secondhand smoke (SHS) exposure during pregnancy and reduction in infant birth weight. The purpose of this cross-sectional study is to examine the magnitude of this association in China, where both prevalence and dose of SHS exposure are thought to be higher than in U.S. populations. Women who gave birth in Beijing and Changchun September 2000–November 2001 were interviewed to quantify self-reported prenatal SHS exposure. Their medical records were reviewed for data on pregnancy complications and birth outcomes. Non-smoking women who delivered term babies (≥37 weeks gestation) were included in the study (N = 2,770). Nearly a quarter of the women (24%) reported daily SHS exposure, 47% reported no prenatal exposure, and 75% denied any SHS exposure from the husband smoking at home. Overall, no deficit in mean birth weight was observed with exposure from all sources of SHS combined (+11 grams, 95% CI: +2, +21). Infants had higher mean birth weights among the exposed than the unexposed for all measures of SHS exposure. Future studies on SHS exposure and infant birth weight in China should emphasize more objective measures of exposure to quantify and account for any exposure misclassification. |
| Posted: 26 Sep 2012 12:00 AM PDT Patients developing the short bowel syndrome (SBS) are at risk for hepatobiliary disease, as are morbidly obese individuals. We hypothesized that morbidly obese SBS individuals would be at increased risk for developing hepatobiliary complications. We reviewed 79 patients with SBS, 53 patients with initial body mass index (BMI) < 35 were controls. Twenty-six patients with initial BMI > 35 were the obese group. Obese patients were more likely to be weaned off parenteral nutrition (PN) (58% vs. 21%). Pre-resection BMI was significantly lower in controls (26 vs. 41). BMI at 1, 2, and 5 years was decreased in controls but persistently increased in obese patients. Obese patients were more likely to undergo cholecystectomy prior to SBS (42% vs. 32%) and after SBS (80% vs. 39%, p < 0.05). Fatty liver was more frequent in the obese group prior to SBS (23% vs. 0%, p < 0.05) but was similar to controls after SBS (23% vs. 15%). Fibrosis (8% vs. 13%) and cirrhosis/portal hypertension (19% vs. 21%) were similar in obese and control groups. Overall, end stage liver disease (ESLD) was similar in obese and control groups (19% vs. 11%) but was significantly higher in obese patients receiving PN (45% vs. 14%, p < 0.05). Obese patients developing SBS are at increased risk of developing hepatobiliary complications. ESLD was similar in the two groups overall but occurs more frequently in obese patients maintained on chronic PN. |
| Posted: 26 Sep 2012 12:00 AM PDT Adult T cell leukemia is a fatal malignant transformation caused by the human T-cell lymphoptropic virus type I (HTLV-I). HTLV-I is only associated with the development of this disease in a small percentage of infected individuals. Using two rabbit transformed T-cell lines; RH/K30 (asymptomatic) and RH/K34 (leukemogenic), we have investigated the expression of heat shock proteins (HSP) 90 and 70 and the role of anti-HSPs antibodies on virus production. HSPs surface expression was higher on RH/K34 than RH/K30 cells. Heat treatment of cells increased the expression of HSPs proteins and virus production; HSPs augmentation was stabilized after 12 h and virus production reached a maximum between 8 h–12 h then returned to normal level after 24 h of culture. Incubation of cells only with rabbit anti-HSP 70 antibodies prevented virus production specifically in the leukemogenic cell line. The results indicate a relationship between HSP 70 and virus production. |
| Community Q&A - Hitman: Absolution Interview Posted: 25 Sep 2012 09:42 PM PDT GameSpot AU hosted an exclusive Hitman: Absolution event which involved a live Q&A with Art Director Roberto Marchesi. Watch him take questions about the Glacier 2 engine, the nun controversy, the origins of Hitman Sniper Challenge and more!
Read and Post Comments | Get the full article at GameSpot "Community Q&A - Hitman: Absolution Interview" was posted by edmondt on Tue, 25 Sep 2012 21:42:07 -0700 |
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