Games |
- PS4 game prices range from 99 cents to $60 according to Tretton
- iDeer Blu-ray Player 1.1.8.1148 - Universal media player. (Demo)
- ProtectMac AntiVirus 1.3.2 - Keeps you safe from viruses and spyware. (Demo)
- CopperCube 4.0.2 - Create interactive 3D scenes without programming. (Demo)
- Radiologik DJ 2013.2.4 - Mixer built specifically for radio DJs. (Demo)
- Radiologik Scheduler 2013.2.4 - Schedule program blocks for Radiologik DJ. (Free)
- Marine Drugs, Vol. 11, Pages 523-550: Jellyfish Stings and Their Management: A Review
- IJMS, Vol. 14, Pages 4372-4374: International Journal of Molecular Science Best Paper Award 2013
- Entropy, Vol. 15, Pages 700-720: Study on the Stability of an Artificial Stock Option Market Based on Bidirectional Conduction
- Sensors, Vol. 13, Pages 2682-2699: A Unified Framework for Activity Recognition-Based Behavior Analysis and Action Prediction in Smart Homes
- Sensors, Vol. 13, Pages 2664-2681: An Incremental Target-Adapted Strategy for Active Geometric Calibration of Projector-Camera Systems
- Toxins, Vol. 5, Pages 456-471: Effect of Gating Modifier Toxins on Membrane Thickness: Implications for Toxin Effect on Gramicidin and Mechanosensitive Channels
- Chatting Columbia With Irrational - Bioshock Infinite
- Big in Asia: Yakuza 5
- Investors Resisting Rogue Apple Shareholder's Calls
- Toxins, Vol. 5, Pages 445-455: Partial Reconstruction of the Ergot Alkaloid Pathway by Heterologous Gene Expression in Aspergillus nidulans
- Agriculture, Vol. 3, Pages 90-111: Pinto Beans (Phaseolus vulgaris L.) as a Functional Food: Implications on Human Health
- JPM, Vol. 3, Pages 23-39: Sensors: Views of Staff of a Disability Service Organization
- Biology, Vol. 2, Pages 331-340: Micro-Eukaryotic Diversity in Hypolithons from Miers Valley, Antarctica
- Materials, Vol. 6, Pages 669-681: Supported Membranes Meet Flat Fluidics: Monitoring Dynamic Cell Adhesion on Pump-Free Microfluidics Chips Functionalized with Supported Membranes Displaying Mannose Domains
| PS4 game prices range from 99 cents to $60 according to Tretton Posted: 22 Feb 2013 03:35 AM PST Those with worries that next-gen game pricing may see a hike might be able to breathe a sigh of relief. According to comments made by Sony Computer |
| iDeer Blu-ray Player 1.1.8.1148 - Universal media player. (Demo) Posted: 22 Feb 2013 03:30 AM PST  iDeer Blu-ray Player is a universal media player software for playing Blu-ray, DVD, BD ISO, DVD ISO, video, audio, music, and photos on the desktop of Macs and Windows PC's. With Arix, it can also play Blu-ray on iPhone/iPad/iPod touch devices. Version 1.1.8.1148:
OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| ProtectMac AntiVirus 1.3.2 - Keeps you safe from viruses and spyware. (Demo) Posted: 22 Feb 2013 03:25 AM PST  ProtectMac AntiVirus is the next generation security product for OS X, designed to keep you safe from viruses and spyware. ProtectMac AntiVirus allows you to scan any area of your Mac or network for both Mac and non-Mac malware. The user-friendly, graphical interface enables you to perform user scans, set up scheduled scans to run in the background, monitor status information and manage any threats that are discovered. ProtectMac AntiVirus automatically checks for updates daily, downloading new threat identities and product updates and installing them without user intervention or the need to restart your Mac. At the heart of the product is a file-access scanner that is always running in the background in real-time checking for threats, intercepting every file that is opened, closed or copied, any application that is launched, any file that is downloaded from the Internet, or email attachment that is extracted. With the ability to scan any device or location directly from Finder's contextual menu, as well as automatic scanning of DVDs, CDs, USB devices, and DMG files as they are mounted, checking for threats on your Mac has never been easier!
OS X 10.4.7 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| CopperCube 4.0.2 - Create interactive 3D scenes without programming. (Demo) Posted: 22 Feb 2013 03:19 AM PST  CopperCube is a 3D editor to create interactive 3D apps - as Flash, standalone Windows .exe, OS X .app, pure JavaScript via WebGL, or Android app - without programming. Create 3D games, model viewers, 3D walkthroughs, 360° panoramas, or camera flights. CopperCube imports 23 different 3D file formats and includes a powerful 3D editor and lightmap generator. All 3D scenes can be scripted using Actionscript 3 or JavaScript. CopperCube can render 3D scenes on websites via Flash or WebGL if available, and on Windows using Direct3D or OpenGL, and uses a highspeed, hardware-accelerated render engine to put out an incredible number of polygons. When publishing your 3D scene as a Flash SWF file it uses a highly optimized and ActionScript 3 based own 3D renderer and still supports advanced features such as BillBoards, Skyboxes, 3D sounds and real lightmaps. CopperCube .SWF 3D files can be easily integrated into your own SWF flash file, be at as beautiful animated 3D background or main 3D environment. It is easily possible to create camera flights or for example first person shooter style controlled walktroughs with CopperCube.
OS X 10.4 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Radiologik DJ 2013.2.4 - Mixer built specifically for radio DJs. (Demo) Posted: 22 Feb 2013 03:10 AM PST  Radiologik DJ is the DJ live assistant specifically built for the needs of radio but very useful for all DJing needs, with the exception of club mix features. It features three main players and one library player, all with selectable individual audio outputs, detailed time calculations, a lot of fast and smooth iTunes integration, and Nicecast artist and title publishing. It is complemented by a free separate scheduler for full station automation. Radiologik DJ has a variety of editions available for purchase. Compare the differences and view the prices of each edition here.
Download Now This posting includes an audio/video/photo media file: Download Now |
| Radiologik Scheduler 2013.2.4 - Schedule program blocks for Radiologik DJ. (Free) Posted: 22 Feb 2013 02:57 AM PST  Radiologik Scheduler schedules program blocks for Radiologik DJ, creating a full-time automated radio station. It chooses tracks from playlists in iTunes with a little bit of extra logic to figure out times and artist separation. It builds these segments in 30, 60, 90 or 120 minute blocks anywhere inside of a week schedule. The resolution of the script statements are in seconds. Playlists, and particularly smart playlists in iTunes, give programming tracks enormous power. Because Radilogik DJ tells iTunes when it plays a track, you can use smart playlists to be sure you are not playing certain songs again for a specified period of time. This can give you a reservoir of tracks that have not played recently but enough tracks to still pick at random, effectively giving a random rotation. You can use many smart playlists for the same segment, giving you the ability to set when to play fast, medium, or slow songs or how often to play tired songs versus new songs that you may want to play more often. Features include automatic placement of voiceover intros and outros, time announcements, date matching picking of file titles, exact time search fitting for to-the second programming, and special scheduling of ad traffic. Radiologik Scheduler runs the appropriate script 20 minutes before the start time and sends that set of tracks and directions to Radiologik DJ's program queue.
OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Marine Drugs, Vol. 11, Pages 523-550: Jellyfish Stings and Their Management: A Review Posted: 22 Feb 2013 12:00 AM PST Jellyfish (cnidarians) have a worldwide distribution. Despite most being harmless, some species may cause local and also systemic reactions. Treatment of jellyfish envenomation is directed at: alleviating the local effects of venom, preventing further nematocyst discharges and controlling systemic reactions, including shock. In severe cases, the most important step is stabilizing and maintaining vital functions. With some differences between species, there seems to be evidence and consensus on oral/topical analgesics, hot water and ice packs as effective painkillers and on 30 s application of domestic vinegar (4%–6% acetic acid) to prevent further discharge of unfired nematocysts remaining on the skin. Conversely, alcohol, methylated spirits and fresh water should be carefully avoided, since they could massively discharge nematocysts; pressure immobilization bandaging should also be avoided, as laboratory studies show that it stimulates additional venom discharge from nematocysts. Most treatment approaches are presently founded on relatively weak evidence; therefore, further research (especially randomized clinical trials) is strongly recommended. Dissemination of appropriate treatment modalities should be deployed to better inform and educate those at risk. Adequate signage should be placed at beaches to notify tourists of the jellyfish risk. Swimmers in risky areas should wear protective equipment. |
| IJMS, Vol. 14, Pages 4372-4374: International Journal of Molecular Science Best Paper Award 2013 Posted: 22 Feb 2013 12:00 AM PST Since 2012, International Journal of Molecular Science has instituted an annual award to recognize outstanding papers in the area of chemistry, molecular physics and molecular biology that meet the aims, scope and high standards of this journal [1]. We are pleased to announce the second "International Journal of Molecular Science Best Paper Award" for 2013. Nominations were made by the Section Editor-in-Chiefs of International Journal of Molecular Science, with all papers published in 2009 eligible for consideration. The awards are issued for reviews and articles separately. |
| Posted: 22 Feb 2013 12:00 AM PST Although stock option markets have grown dramatically over the past several decades, the relation between an option and its underlying asset, especially bidirectional conduction, is not particularly clear. So far, there have been many debates about this topic. We try to investigate this problem from a novel angle: an artificial stock market including a stock option is constructed in this paper. The model includes two parts, one is a stock trade module based on the Santa Fe Institute Artificial Stock Market (SFI-ASM), and the other is an option trade module. In the latter module, three types of option traders are employed. The results show that the model is effective, and experiments illustrate that option markets have a remarkable effect on stock markets. Furthermore, by appending options, the model replicates some stylized properties, such as volatility clustering and GARCH effect, which can be observed in real financial markets. |
| Posted: 22 Feb 2013 12:00 AM PST In recent years, activity recognition in smart homes is an active research area due to its applicability in many applications, such as assistive living and healthcare. Besides activity recognition, the information collected from smart homes has great potential for other application domains like lifestyle analysis, security and surveillance, and interaction monitoring. Therefore, discovery of users common behaviors and prediction of future actions from past behaviors become an important step towards allowing an environment to provide personalized service. In this paper, we develop a unified framework for activity recognition-based behavior analysis and action prediction. For this purpose, first we propose kernel fusion method for accurate activity recognition and then identify the significant sequential behaviors of inhabitants from recognized activities of their daily routines. Moreover, behaviors patterns are further utilized to predict the future actions from past activities. To evaluate the proposed framework, we performed experiments on two real datasets. The results show a remarkable improvement of 13.82% in the accuracy on average of recognized activities along with the extraction of significant behavioral patterns and precise activity predictions with 6.76% increase in F-measure. All this collectively help in understanding the users" actions to gain knowledge about their habits and preferences. |
| Posted: 22 Feb 2013 12:00 AM PST The calibration of a projector-camera system is an essential step toward accurate 3-D measurement and environment-aware data projection applications, such as augmented reality. In this paper we present a two-stage easy-to-deploy strategy for robust calibration of both intrinsic and extrinsic parameters of a projector. Two key components of the system are the automatic generation of projected light patterns and the incremental calibration process. Based on the incremental strategy, the calibration process first establishes a set of initial parameters, and then it upgrades these parameters incrementally using the projection and captured images of dynamically-generated calibration patterns. The scene-driven light patterns allow the system to adapt itself to the pose of the calibration target, such that the difficulty in feature detection is greatly lowered. The strategy forms a closed-loop system that performs self-correction as more and more observations become available. Compared to the conventional method, which requires a time-consuming process for the acquisition of dense pixel correspondences, the proposed method deploys a homography-based coordinate computation, allowing the calibration time to be dramatically reduced. The experimental results indicate that an improvement of 70% in reprojection errors is achievable and 95% of the calibration time can be saved. |
| Posted: 22 Feb 2013 12:00 AM PST Various gating modifier toxins partition into membranes and interfere with the gating mechanisms of biological ion channels. For example, GsMTx4 potentiates gramicidin and several bacterial mechanosensitive channels whose gating kinetics are sensitive to mechanical properties of the membrane, whereas binding of HpTx2 shifts the voltage-activity curve of the voltage-gated potassium channel Kv4.2 to the right. The detailed process by which the toxin partitions into membranes has been difficult to probe using molecular dynamics due to the limited time scale accessible. Here we develop a protocol that allows the spontaneous assembly of a polypeptide toxin into membranes in atomistic molecular dynamics simulations of tens of nanoseconds. The protocol is applied to GsMTx4 and HpTx2. Both toxins, released in water at the start of the simulation, spontaneously bind into the lipid bilayer within 50 ns, with their hydrophobic patch penetrated into the bilayer beyond the phosphate groups of the lipids. It is found that the bilayer is about 2 Å thinner upon the binding of a GsMTx4 monomer. Such a thinning effect of GsMTx4 on membranes may explain its potentiation effect on gramicidin and mechanosensitive channels. |
| Chatting Columbia With Irrational - Bioshock Infinite Posted: 22 Feb 2013 12:12 AM PST Dan Chiappini sits down with Irrational's User Experience Specialist Bill Gardener to give us a developer walkthrough of some brand new Bioshock Infinite footage, and have a long candid chat about the game and what we can all expect from Columbia!
Read and Post Comments | Get the full article at GameSpot "Chatting Columbia With Irrational - Bioshock Infinite" was posted by edmondt on Fri, 22 Feb 2013 00:12:44 -0800 |
| Posted: 21 Feb 2013 10:08 PM PST Bears! J-Pop Idols! Gang Warfare! Jonathan and Randolph venture into the insane world of Yakuza 5 in this installment of our Big in Asia livestream replay.
Read and Post Comments | Get the full article at GameSpot "Big in Asia: Yakuza 5" was posted by rreydebarros on Thu, 21 Feb 2013 22:08:26 -0800 |
| Investors Resisting Rogue Apple Shareholder's Calls Posted: 22 Feb 2013 02:05 AM PST Hedge fund manager David Einhorn competing in the World Series of Poker in 2006. This posting includes an audio/video/photo media file: Download Now |
| Posted: 22 Feb 2013 12:00 AM PST Ergot alkaloids are pharmaceutically and agriculturally important secondary metabolites produced by several species of fungi. Ergot alkaloid pathways vary among different fungal lineages, but the pathway intermediate chanoclavine-I is evolutionarily conserved among ergot alkaloid producers. At least four genes, dmaW, easF, easE, and easC, are necessary for pathway steps prior to chanoclavine-I; however, the sufficiency of these genes for chanoclavine-I synthesis has not been established. A fragment of genomic DNA containing dmaW, easF, easE, and easC was amplified from the human-pathogenic, ergot alkaloid-producing fungus Aspergillus fumigatus and transformed into Aspergillus nidulans, a model fungus that does not contain any of the ergot alkaloid synthesis genes. HPLC and LC-MS analyses demonstrated that transformed A. nidulans strains produced chanoclavine-I and an earlier pathway intermediate. Aspergillus nidulans transformants containing dmaW, easF, and either easE or easC did not produce chanoclavine-I but did produce an early pathway intermediate and, in the case of the easC transformant, an additional ergot alkaloid-like compound. We conclude that dmaW, easF, easE, and easC are sufficient for the synthesis of chanoclavine-I in A. nidulans and expressing ergot alkaloid pathway genes in A. nidulans provides a novel approach to understanding the early steps in ergot alkaloid synthesis. |
| Posted: 22 Feb 2013 12:00 AM PST Most foods are considered functional in terms of providing nutrients and energy to sustain daily life, but dietary systems that are capable of preventing or remediating a stressed or diseased state are classified as functional foods. Dry beans (Phaseolus vulgaris L.) contain high levels of chemically diverse components (phenols, resistance starch, vitamins, fructooligosaccharides) that have shown to protect against such conditions as oxidative stress, cardiovascular disease, diabetes, metabolic syndrome, and many types of cancer, thereby positioning this legume as an excellent functional food. Moreover, the United States has a rich dry bean history and is currently a top producer of dry beans in the world with pinto beans accounting for the vast majority. Despite these attributes, dry bean consumption in the US remains relatively low. Therefore, the objective of this manuscript is to review dry beans as an important US agricultural crop and as functional food for the present age with an emphasis on pinto beans. |
| JPM, Vol. 3, Pages 23-39: Sensors: Views of Staff of a Disability Service Organization Posted: 22 Feb 2013 12:00 AM PST Sensors have become ubiquitous in their reach and scope of application. They are a technological cornerstone for various modes of health surveillance and participatory medicine—such as quantifying oneself; they are also employed to track people with certain as impairments perceived ability differences. This paper presents quantitative and qualitative data of an exploratory, non-generalizable study into the perceptions, attitudes and concerns of staff of a disability service organization, that mostly serve people with intellectual disabilities, towards the use of various types of sensor technologies that might be used by and with their clients. In addition, perspectives of various types of privacy issues linked to sensors, as well data regarding the concept of quantified self were obtained. Our results highlight the need to involve disabled people and their support networks in sensor and quantified-self discourses, in order to prevent undue disadvantages. |
| Posted: 22 Feb 2013 12:00 AM PST The discovery of extensive and complex hypolithic communities in both cold and hot deserts has raised many questions regarding their ecology, biodiversity and relevance in terms of regional productivity. However, most hypolithic research has focused on the bacterial elements of the community. This study represents the first investigation of micro-eukaryotic communities in all three hypolith types. Here we show that Antarctic hypoliths support extensive populations of novel uncharacterized bryophyta, fungi and protists and suggest that well known producer-decomposer-predator interactions may create the necessary conditions for hypolithic productivity in Antarctic deserts. |
| Posted: 22 Feb 2013 12:00 AM PST In this paper we demonstrate the combination of supported membranes and so-called flat microfluidics, which enables one to manipulate liquids on flat chip surfaces via "inverse piezoelectric effect". Here, an alternating external electric field applied to the inter-digital transducers excites a surface acoustic wave on a piezoelectric substrate. Employing lithographic patterning of self-assembled monolayers of alkoxysilanes, we successfully confine a free-standing, hemi-cylindrical channel with the volume of merely 7 µL . The experimentally determined maximum flow velocity scales linearly with the acoustic power, suggesting that our current setup can drive liquids at the speed of up to 7 cm/s (corresponding to a shear rate of 280 s−1) without applying high pressures using a fluidic pump. After the establishment of the functionalization of fluidic chip surfaces with supported membranes, we deposited asymmetric supported membranes displaying well-defined mannose domains and monitored the dynamic adhesion of E. Coli HB101 expressing mannose-binding receptors. Despite of the further technical optimization required for the quantitative analysis, the obtained results demonstrate that the combination of supported membranes and flat fluidics opens a large potential to investigate dynamic adhesion of cells on biofunctional membrane surfaces with the minimum amount of samples, without any fluidic pump. |
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