Games |
- iShare Money 1.1 - Put your image on dollar bills.. (Commercial)
- Organize:Me Personal Task Manager 1.5.0 - Personal task manager.. (Demo)
- UltraMixer 4.0.1 - Pro DJ mixing software (release candidate).. (Demo)
- Entropy, Vol. 15, Pages 524-543: On Thermodynamic Interpretation of Transfer Entropy
- Sustainability, Vol. 5, Pages 524-559: An Integrated Model Based on a Hierarchical Indices System for Monitoring and Evaluating Urban Sustainability
- Sustainability, Vol. 5, Pages 496-523: The Regional Index of Sustainable Economic Welfare for Flanders, Belgium
- IJMS, Vol. 14, Pages 3124-3139: Optimization of the Preparation of Fish Protein Anti-Obesity Hydrolysates Using Response Surface Methodology
- IJMS, Vol. 14, Pages 3110-3123: Analysis of Expressed Sequence Tags from Chinese Bayberry Fruit (Myrica rubra Sieb. and Zucc.) at Different Ripening Stages and Their Association with Fruit Quality Development
- IJERPH, Vol. 10, Pages 568-570: Child Injury Prevention: An Overlooked Challenge for Child Survival
- Arrests Made In Illegal Gaming Bust
- Sound Byte: Meet the Performer - Malaysian guest artist for Distant Worlds
- Nanomaterials, Vol. 3, Pages 107-116: Assembl y of Poly-3-Hexylthiophene Nano-Crystallites into Low Dimensional Structures Using Indandione Derivatives
- Sensors, Vol. 13, Pages 1902-1918: 3D LIDAR-Camera Extrinsic Calibration Using an Arbitrary Trihedron
- Sensors, Vol. 13, Pages 1884-1901: A Silicon Carbide Wireless Temperature Sensing System for High Temperature Applications
- Chess champs defy stereotypes
- Sensors, Vol. 13, Pages 1872-1883: Visible/Near Infrared Spectroscopy and Chemometrics for the Prediction of Trace Element (Fe and Zn) Levels in Rice Leaf
- IJMS, Vol. 14, Pages 3094-3109: Amplification Target ADRM1: Role as an Oncogene and Therapeutic Target for Ovarian Cancer
- IJMS, Vol. 14, Pages 3078-3093: A Comparative Study of Selected Trace Element Content in Malay and Chinese Traditional Herbal Medicine (THM) Using an Inductively Coupled Plasma-Mass Spectrometer (ICP-MS)
- IJMS, Vol. 14, Pages 3065-3077: Cytotoxicity and Genotoxicity of Ceria Nanoparticles on Different Cell Lines in Vitro
- IJMS, Vol. 14, Pages 3050-3064: Sodium Dodecyl Sulfate (SDS)-Loaded Nanoporous Polymer as Anti-Biofilm Surface Coating Material
| iShare Money 1.1 - Put your image on dollar bills.. (Commercial) Posted: 01 Feb 2013 03:24 AM PST  iShare Money lets you create your own dollars and share them with all your friends! Version 1.1:
Download Now |
| Organize:Me Personal Task Manager 1.5.0 - Personal task manager.. (Demo) Posted: 01 Feb 2013 03:14 AM PST  The new Organize:Me 1.5 is your personal task manager if you're really serious about getting your stuff done! Organize:Me is easy to use, but still supports your organizational method of choice - from Getting Things Done (GTD) to PRINCE. It's available on Windows, Mac, iPad and iPhone with free Cloud Sync to share your tasks between all installations. This makes it easy to use the same tool wherever you are - no matter if you have a PC, Mac or just an iPad in front of you. More than 200,000 new users in 2012 made the Organize family the first choice for serious task management! And now we're starting off into the new year with a new, improved version that makes it even easier to start with serious task management. If you're looking for a tool to make your new years resolutions come true, Organize:Me is the tool that really helps you doing it! Organize:Me basic task management features
Version 1.5.0:
OS X 10.6.6 or newer Download Now This posting includes an audio/video/photo media file: Download Now |
| UltraMixer 4.0.1 - Pro DJ mixing software (release candidate).. (Demo) Posted: 01 Feb 2013 03:02 AM PST  UltraMixer is a professional DJ mixing software which enables you to mix digital music in various formats such as MP3, WMA, OGG, WAV or CDs in real time. All you need is a sound card. The DJ's turntables are replaced by two digital SoundPlayers, the "vinyls" are available within seconds through the integrated FileArchive. No matter whether you want to use UltraMixer for a professional gig or at a private party or as virtual jukebox in restaurants, hair studios or medical surgeries - it will prove the right choice! UltraMixer is the first DJ software in the world that is available for the most popular operating systems: Mac OS X, Linux, and Windows. There are three versions of UltraMixer available: the Free-Edition and the Basic-Edition for private users and the Advanced-Edition for high demands and commerical use. All versions are integrated in one program, and can be activated through the appropriate licence keys. This enables the user to switch to a more advanced version without any problems. Version 4.0.1 (RC4): Release notes were unavailable when this listing was updated. OS X 10.6.8 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Entropy, Vol. 15, Pages 524-543: On Thermodynamic Interpretation of Transfer Entropy Posted: 01 Feb 2013 12:00 AM PST We propose a thermodynamic interpretation of transfer entropy near equilibrium, using a specialised Boltzmann’s principle. The approach relates conditional probabilities to the probabilities of the corresponding state transitions. This in turn characterises transfer entropy as a difference of two entropy rates: the rate for a resultant transition and another rate for a possibly irreversible transition within the system affected by an additional source. We then show that this difference, the local transfer entropy, is proportional to the external entropy production, possibly due to irreversibility. Near equilibrium, transfer entropy is also interpreted as the difference in equilibrium stabilities with respect to two scenarios: a default case and the case with an additional source. Finally, we demonstrated that such a thermodynamic treatment is not applicable to information flow, a measure of causal effect. |
| Posted: 01 Feb 2013 12:00 AM PST Over 50% of world’s population presently resides in cities, and this number is expected to rise to ~70% by 2050. Increasing urbanization problems including population growth, urban sprawl, land use change, unemployment, and environmental degradation, have markedly impacted urban residents’ Quality of Life (QOL). Therefore, urban sustainability and its measurement have gained increasing attention from administrators, urban planners, and scientific communities throughout the world with respect to improving urban development and human well-being. The widely accepted definition of urban sustainability emphasizes the balancing development of three primary domains (urban economy, society, and environment). This article attempts to improve the aforementioned definition of urban sustainability by incorporating a human well-being dimension. Major problems identified in existing urban sustainability indicator (USI) models include a weak integration of potential indicators, poor measurement and quantification, and insufficient spatial-temporal analysis. To tackle these challenges an integrated USI model based on a hierarchical indices system was established for monitoring and evaluating urban sustainability. This model can be performed by quantifying indicators using both traditional statistical approaches and advanced geomatic techniques based on satellite imagery and census data, which aims to provide a theoretical basis for a comprehensive assessment of urban sustainability from a spatial-temporal perspective. |
| Posted: 01 Feb 2013 12:00 AM PST In this paper, the regional Index of Sustainable Economic Welfare (ISEW) is compiled for Flanders for the period 1990–2009. The ISEW is a measure of economic welfare in that it measures the contribution of a country’s or region’s economy to the overall level of well-being of its citizens. It does so by comparing the benefits and the costs of economic activities rather than simply looking at the market value of all final goods and services produced in an economy (Gross Domestic Product-GDP). The ISEW for Flanders shows that the per capita level of sustainable economic welfare in the region decreased between 1990 and 2009. The drop in the ISEW/capita is caused by a deterioration of the net international investment position of Belgium (which is divided over the different regions in the country on a per capita basis) and by an increase in the income inequalities in Flanders. To a lesser extent, the increase of the environmental costs (climate change and the use of non-renewable energy resources) also contributed to the decrease in the ISEW per capita. In the last four years of the study period, the level of sustainable economic welfare in the Flemish region started to rise again, even in 2008 and 2009 during the economic recession. |
| Posted: 01 Feb 2013 12:00 AM PST The enzymatic condition for producing the anti-obesity hydrolysates from fish water-soluble protein was optimized with the aid of response surface methodology, which also derived a statistical model for experimental validation. Compared with neutral protease, papain and protamex, the porcine pancreas lipase inhibitory rate of hydrolysates from fish water-soluble protein was higher with alkaline protease. Results showed that the model terms were significant, the terms of lack of fit were not significant, and the optimal conditions for the hydrolysis by alkaline protease were initial pH 11, temperature 39 °C, enzyme dosage 122 U/mL and 10 h of hydrolysis time. Under these conditions, the porcine pancreas lipase and the α-amylase inhibitory rate could reach 53.04% ± 1.32% and 20.03 ± 0.89%, while predicted value were 54.63% ± 1.75%, 21.22% ± 0.70%, respectively. In addition, Lineweaver-Burk plots showed noncompetitive inhibition. The Ki value calculated was 84.13 mg/mL. These results demonstrated that fish water-soluble protein could be used for obtaining anti-obesity hydrolysates. |
| Posted: 01 Feb 2013 12:00 AM PST A total of 2000 EST sequences were produced from cDNA libraries generated from Chinese bayberry fruit (Myrica rubra Sieb. and Zucc. cv. “Biqi”) at four different ripening stages. After cluster and assembly analysis of the datasets by UniProt, 395 unigenes were identified, and their presumed functions were assigned to 14 putative cellular roles. Furthermore, a sequence BLAST was done for the top ten highly expressed genes in the ESTs, and genes associated with disease/defense and anthocyanin accumulation were analyzed. Gene-encoding elements associated with ethylene biosynthesis and signal transductions, in addition to other senescence-regulating proteins, as well as those associated with quality formation during fruit ripening, were also identified. Their possible roles were subsequently discussed. |
| IJERPH, Vol. 10, Pages 568-570: Child Injury Prevention: An Overlooked Challenge for Child Survival Posted: 01 Feb 2013 12:00 AM PST Those interested in child survival frequently cite and follow the under-five mortality rate. While a useful measure, the under-five mortality rate lumps together neonatal and post-neonatal mortality with deaths in the 1–4 year period. Unfortunately, this hampers public health decision making about the most appropriate child survival strategies as children survive beyond their first year of life. |
| Arrests Made In Illegal Gaming Bust Posted: 01 Feb 2013 02:41 AM PST The Richland County Sheriff's Department said earlier this month they would begin cracking down on video gambling, Internet sweepstakes, or similar machines in Richland County. This posting includes an audio/video/photo media file: Download Now |
| Sound Byte: Meet the Performer - Malaysian guest artist for Distant Worlds Posted: 01 Feb 2013 12:02 AM PST We had a short online chat with Az Samad, a Malaysian guitarist and composer who was a guest performer for Square Enix's Final Fantasy-themed music concert.
Get the full article at GameSpot "Sound Byte: Meet the Performer - Malaysian guest artist for Distant Worlds" was posted by Jonathan Toyad on Fri, 01 Feb 2013 00:02:02 -0800 |
| Posted: 01 Feb 2013 12:00 AM PST Conductive polymer poly-3-hexylthiophene (P3HT) needles were self-assembled using a second component (indandione derivatives) as a linking agent to enhance their long range alignment. The morphologies of the hybrid organic/organic materials were characterized by transmission electron microscopy (TEM). Both linear and branched structures could be produced, with the degree of branching depending upon the linker used. Incorporation of indandione derivatives broadened the UV absorbance band of P3HT without significant change to its photoluminescence. This hybrid material could open a promising avenue in photovoltaic applications due to its interesting morphologies and optical properties. |
| Posted: 01 Feb 2013 12:00 AM PST This paper presents a novel way to address the extrinsic calibration problem for a system composed of a 3D LIDAR and a camera. The relative transformation between the two sensors is calibrated via a nonlinear least squares (NLS) problem, which is formulated in terms of the geometric constraints associated with a trihedral object. Precise initial estimates of NLS are obtained by dividing it into two sub-problems that are solved individually. With the precise initializations, the calibration parameters are further refined by iteratively optimizing the NLS problem. The algorithm is validated on both simulated and real data, as well as a 3D reconstruction application. Moreover, since the trihedral target used for calibration can be either orthogonal or not, it is very often present in structured environments, making the calibration convenient. |
| Posted: 01 Feb 2013 12:00 AM PST In this article, an extreme environment-capable temperature sensing system based on state-of-art silicon carbide (SiC) wireless electronics is presented. In conjunction with a Pt-Pb thermocouple, the SiC wireless sensor suite is operable at 450 °C while under centrifugal load greater than 1,000 g. This SiC wireless temperature sensing system is designed to be non-intrusively embedded inside the gas turbine generators, acquiring the temperature information of critical components such as turbine blades, and wirelessly transmitting the information to the receiver located outside the turbine engine. A prototype system was developed and verified up to 450 °C through high temperature lab testing. The combination of the extreme temperature SiC wireless telemetry technology and integrated harsh environment sensors will allow for condition-based in-situ maintenance of power generators and aircraft turbines in field operation, and can be applied in many other industries requiring extreme environment monitoring and maintenance. |
| Posted: 01 Feb 2013 01:41 AM PST Chess tends to be the domain of privileged schools whose star players have had their own personal chess coaches. This posting includes an audio/video/photo media file: Download Now |
| Posted: 01 Feb 2013 12:00 AM PST Two sensitive wavelength (SW) selection methods combined with visible/near infrared (Vis/NIR) spectroscopy were investigated to determine the levels of some trace elements (Fe, Zn) in rice leaf. A total of 90 samples were prepared for the calibration (n = 70) and validation (n = 20) sets. Calibration models using SWs selected by LVA and ICA were developed and nonlinear regression of a least squares-support vector machine (LS-SVM) was built. In the nonlinear models, six SWs selected by ICA can provide the optimal ICA-LS-SVM model when compared with LV-LS-SVM. The coefficients of determination (R2), root mean square error of prediction (RMSEP) and bias by ICA-LS-SVM were 0.6189, 20.6510 ppm and −12.1549 ppm, respectively, for Fe, and 0.6731, 5.5919 ppm and 1.5232 ppm, respectively, for Zn. The overall results indicated that ICA was a powerful way for the selection of SWs, and Vis/NIR spectroscopy combined with ICA-LS-SVM was very efficient in terms of accurate determination of trace elements in rice leaf. |
| Posted: 01 Feb 2013 12:00 AM PST Approximately 25,000 ovarian cancers are diagnosed in the U.S. annually, and 75% are in the advanced stage and largely incurable. There is critical need for early detection tools and novel treatments. Proteasomal ubiquitin receptor ADRM1 is a protein that is encoded by the ADRM1 gene. Recently, we showed that among 20q13-amplified genes in ovarian cancer, ADRM1 overexpression was the most highly correlated with amplification and was significantly upregulated with respect to stage, recurrence, and metastasis. Its overexpression correlated significantly with shorter time to recurrence and overall survival. Array-CGH and microarray expression of ovarian cancer cell lines provided evidence consistent with primary tumor data that ADRM1 is a 20q13 amplification target. Herein, we confirm the ADRM1 amplicon in a second ovarian cancer cohort and define a minimally amplified region of 262 KB encompassing seven genes. Additionally, using RNAi knock-down of ADRM1 in naturally amplified cell line OAW42 and overexpression of ADRM1 via transfection in ES2, we show that (1) ADRM1 overexpression increases proliferation, migration, and growth in soft agar, and (2) knock-down of ADRM1 results in apoptosis. Proteomic analysis of cells with ADRM1 knock-down reveals dysregulation of proteins including CDK-activating kinase assembly factor MAT1. Taken together, the results indicate that amplified ADRM1 is involved in cell proliferation, migration and survival in ovarian cancer cells, supporting a role as an oncogene and novel therapeutic target for ovarian cancer. |
| Posted: 01 Feb 2013 12:00 AM PST A total of 60 products of traditional herbal medicine (THM) in various dosage forms of herbal preparation were analyzed to determine selected trace elements (i.e., Zn, Mn, Cu, Cd, and Se) using ICP-MS. Thirty types of both Chinese and Malay THMs were chosen to represent each population. The closed vessel acid microwave digestion method, using CEM MARS 5, was employed for the extraction of the selected trace elements. The digestion method applied was validated by using certified reference material from the Trace Element in Spinach Leaves (SRM1570a). The recoveries of all elements were found to be in the range of 85.3%–98.9%. The results indicated that Zn, Mn, Cu, Cd and Se have their own trends of concentrations in all samples studied. The daily intake concentrations of the elements were in the following order: Mn > Zn > Cu > Se > Cd. Concentrations of all five elements were found to be dominant in Chinese THMs. The essentiality of the selected trace elements was also assessed, based on the recommended daily allowance (RDA), adequate intake (AI) and the United States Pharmacopeia (USP) for trace elements as reference. The concentrations of all elements studied were below the RDA, AI and USP values, which fall within the essential concentration range, except for cadmium. |
| Posted: 01 Feb 2013 12:00 AM PST Owing to their radical scavenging and UV-filtering properties, ceria nanoparticles (CeO2-NPs) are currently used for various applications, including as catalysts in diesel particulate filters. Because of their ability to filter UV light, CeO2-NPs have garnered significant interest in the medical field and, consequently, are poised for use in various applications. The aim of this work was to investigate the effects of short-term (24 h) and long-term (10 days) CeO2-NP exposure to A549, CaCo2 and HepG2 cell lines. Cytotoxicity assays tested CeO2-NPs over a concentration range of 0.5 μg/mL to 5000 μg/mL, whereas genotoxicity assays tested CeO2-NPs over a concentration range of 0.5 μg/mL to 5000 μg/mL. In vitro assays showed almost no short-term exposure toxicity on any of the tested cell lines. Conversely, long-term CeO2-NP exposure proved toxic for all tested cell lines. NP genotoxicity was detectable even at 24-h exposure. HepG2 was the most sensitive cell line overall; however, the A549 line was most sensitive to the lowest concentration tested. Moreover, the results confirmed the ceria nanoparticles’ capacity to protect cells when they are exposed to well-known oxidants such as H2O2. A Comet assay was performed in the presence of both H2O2 and CeO2-NPs. When hydrogen peroxide was maintained at 25 μM, NPs at 0.5 μg/mL, 50 μg/mL, and 500 μg/mL protected the cells from oxidative damage. Thus, the NPs prevented H2O2-induced genotoxic damage. |
| Posted: 01 Feb 2013 12:00 AM PST Biofilms cause extensive damage to industrial settings. Thus, it is important to improve the existing techniques and develop new strategies to prevent bacterial biofilm formation. In the present study, we have prepared nanoporous polymer films from a self-assembled 1,2-polybutadiene-b-polydimethylsiloxane (1,2-PB-b-PDMS) block copolymer via chemical cross-linking of the 1,2-PB block followed by quantitative removal of the PDMS block. Sodium dodecyl sulfate (SDS) was loaded into the nanoporous 1,2-PB from aqueous solution. The SDS-loaded nanoporous polymer films were shown to block bacterial attachment in short-term (3 h) and significantly reduce biofilm formation in long-term (1 week) by gram-negative bacterium Escherichia coli. Tuning the thickness or surface morphology of the nanoporous polymer films allowed to extent the anti-biofilm capability. |
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