Games |
- Maxthon 4.0.4.2000 - Safe, fast, accessible Web browser. (Free)
- M4VConverterPlus 3.0.0 - Convert videos and extract audio. (Shareware)
- Sensors, Vol. 13, Pages 5528-5541: A Compact and Low Cost Electronic Nose for Aroma Detection
- Sensors, Vol. 13, Pages 5507-5527: A Hilbert Transform-Based Smart Sensor for Detection, Classification, and Quantification of Power Quality Disturbances
- Talisman Prologue - Screenshots
- Posterino 2.6.3 - Create posters, calendars and postcards. (Demo)
- Dash 1.8.3 - Code snippet manager and Cocoa documentation browser. (Shareware)
- Metropolis 1.03 - Flexible WordPress client. (Demo)
- Sensors, Vol. 13, Pages 5493-5506: A Molecularly Imprinted Polymer with Incorporated Graphene Oxide for Electrochemical Determination of Quercetin
- Sensors, Vol. 13, Pages 5478-5492: Flexible PZT Thin Film Tactile Sensor for Biomedical Monitoring
- IJMS, Vol. 14, Pages 9099-9110: Expression Pattern of Small Nucleolar RNA Host Genes and Long Non-Coding RNA in X-rays-Treated Lymphoblastoid Cells
- IJMS, Vol. 14, Pages 9080-9098: Transcriptome Analysis of Thapsia laciniata Rouy Provides Insights into Terpenoid Biosynthesis and Diversity in Apiaceae
- Entropy, Vol. 15, Pages 1516-1527: Phase-Space Position-Momentum Correlation and Potentials
- 1Password 3.8.21 - Powerful password manager; integrates with Web browsers and more. (Shareware)
- fp 6.1 - Unlimited length integers and more for Xcode C++. (Free)
- Entropy, Vol. 15, Pages 1503-1515: Time Reversibility, Correlation Decay and the Steady State Fluctuation Relation for Dissipation
- Entropy, Vol. 15, Pages 1486-1502: Discretization Based on Entropy and Multiple Scanning
- IJMS, Vol. 14, Pages 9062-9079: Phylogeography and Genetic Differentiation among Populations of the Moon Turban Snail Lunella granulata Gmelin, 1791 (Gastropoda: Turbinidae)
- Molecules, Vol. 18, Pages 4917-4928: A Preliminary Study of the Effect of DBD Plasma and Osmolytes on T98G Brain Cancer and HEK Non-Malignant Cells
- Molecules, Vol. 18, Pages 4906-4916: Zero-Point Corrections for Isotropic Coupling Constants for Cyclohexadienyl Radical, C6H7 and C6H6Mu: Beyond the Bond Length Change Approximation
Maxthon 4.0.4.2000 - Safe, fast, accessible Web browser. (Free) Posted: 25 Apr 2013 03:23 AM PDT Maxthon is the browser that doesn't crash and runs smoothly.
Version 4.0.4.2000: New Features:
OS X 10.6 or later Download Now This posting includes an audio/video/photo media file: Download Now |
M4VConverterPlus 3.0.0 - Convert videos and extract audio. (Shareware) Posted: 25 Apr 2013 03:14 AM PDT M4VConverterPlus uses multiple-speed recording technology to record M4V, then decodes to unprotected MOV, M4V, or MP4 format. It has been designed for removing DRM from iTunes, such as purchased iTunes movies and iTunes movie rentals. It can also convert any video in your iTunes library. It supports extracting the audio from M4V files. Batch conversion is supported by this powerful m4v converter. It is a universal application. Version 3.0.0:
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Sensors, Vol. 13, Pages 5528-5541: A Compact and Low Cost Electronic Nose for Aroma Detection Posted: 25 Apr 2013 12:00 AM PDT This article explains the development of a prototype of a portable and a very low-cost electronic nose based on an mbed microcontroller. Mbeds are a series of ARM microcontroller development boards designed for fast, flexible and rapid prototyping. The electronic nose is comprised of an mbed, an LCD display, two small pumps, two electro-valves and a sensor chamber with four TGS Figaro gas sensors. The performance of the electronic nose has been tested by measuring the ethanol content of wine synthetic matrices and special attention has been paid to the reproducibility and repeatability of the measurements taken on different days. Results show that the electronic nose with a neural network classifier is able to discriminate wine samples with 10, 12 and 14% V/V alcohol content with a classification error of less than 1%. |
Posted: 25 Apr 2013 12:00 AM PDT Power quality disturbance (PQD) monitoring has become an important issue due to the growing number of disturbing loads connected to the power line and to the susceptibility of certain loads to their presence. In any real power system, there are multiple sources of several disturbances which can have different magnitudes and appear at different times. In order to avoid equipment damage and estimate the damage severity, they have to be detected, classified, and quantified. In this work, a smart sensor for detection, classification, and quantification of PQD is proposed. First, the Hilbert transform (HT) is used as detection technique; then, the classification of the envelope of a PQD obtained through HT is carried out by a feed forward neural network (FFNN). Finally, the root mean square voltage (Vrms), peak voltage (Vpeak), crest factor (CF), and total harmonic distortion (THD) indices calculated through HT and Parseval's theorem as well as an instantaneous exponential time constant quantify the PQD according to the disturbance presented. The aforementioned methodology is processed online using digital hardware signal processing based on field programmable gate array (FPGA). Besides, the proposed smart sensor performance is validated and tested through synthetic signals and under real operating conditions, respectively. |
Talisman Prologue - Screenshots Posted: 25 Apr 2013 04:25 AM PDT Key features - 10 classic characters from the board game - 50 quests to play through - Original soundtrack - Endless replayability - Watch out for new characters and quests coming by updates |
Posterino 2.6.3 - Create posters, calendars and postcards. (Demo) Posted: 25 Apr 2013 03:08 AM PDT Posterino offers enhanced customization and flexibility including a variety of new, stylish templates featuring grids of identical or odd-sized image boxes. You can customize the size and shape of these boxes at any time. And with a single click, the application will automatically fill those boxes with random images drawn from the photos you uploaded. If you prefer to manually select images, you can simply drag and drop images into the template. Sharing your photos is quick and simple as well. You can directly upload your completed collages to your Flickr account from inside the app, and export photos to iPhoto and your email. Posterino 2 also lets you create and send custom e-cards with your very own stamps and postmarks. Posterino 2 lets you:
Version 2.6.3:
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Dash 1.8.3 - Code snippet manager and Cocoa documentation browser. (Shareware) Posted: 25 Apr 2013 03:00 AM PDT Dash is an API documentation browser and code-snippet manager. Always one keyboard shortcut away, Dash helps you store snippets of code, as well as search iOS, Mac, Android, Java, Perl, Ruby, PHP, Python, jQuery, Django, Cocos2D, and a lot more docsets. Snippet Manager Features:
Version 1.8.3:
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Metropolis 1.03 - Flexible WordPress client. (Demo) Posted: 25 Apr 2013 02:52 AM PDT Metropolis is a smart and powerful WordPress client that features offline support, pages, comments, posts, Twitter integration, and more. Create and Edit Pages Work Offline Socialize Comments Other Features
Version 1.03:
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Posted: 25 Apr 2013 12:00 AM PDT The molecularly imprinted polymer based on polypyrrole film with incorporated graphene oxide was fabricated and used for electrochemical determination of quercetin. The electrochemical behavior of quercetin on the modified electrode was studied in detail using differential pulse voltammetry. The oxidation peak current of quercetin in B-R buffer solution (pH = 3.5) at the modified electrode was regressed with the concentration in the range from 6.0 × 10−7 to 1.5 × 10−5 mol/L (r2 = 0.997) with a detection limit of 4.8 × 10−8 mol/L (S/N = 3). This electrode showed good stability and reproducibility. In the above mentioned range, rutin or morin which has similar structures and at the same concentration as quercetin did not interfere with the determination of quercetin. The applicability of the method for complex matrix analysis was also evaluated. |
Sensors, Vol. 13, Pages 5478-5492: Flexible PZT Thin Film Tactile Sensor for Biomedical Monitoring Posted: 25 Apr 2013 12:00 AM PDT This paper presents the development of tactile sensors using the sol-gel process to deposit a PZT thin-film from 250 nm to 1 μm on a flexible stainless steel substrate. The PZT thin-film tactile sensor can be used to measure human pulses from several areas, including carotid, brachial, finger, ankle, radial artery, and the apical region. Flexible PZT tactile sensors can overcome the diverse topology of various human regions and sense the corresponding signals from human bodies. The measured arterial pulse waveform can be used to diagnose hypertension and cardiac failure in patients. The proposed sensors have several advantages, such as flexibility, reliability, high strain, low cost, simple fabrication, and low temperature processing. The PZT thin-film deposition process includes a pyrolysis process at 150 °C/500 °C for 10/5 min, followed by an annealing process at 650 °C for 10 min. Finally, the consistent pulse wave velocity (PWV) was demonstrated based on human pulse measurements from apical to radial, brachial to radial, and radial to ankle. It is characterized that the sensitivity of our PZT-based tactile sensor was approximately 0.798 mV/g. |
Posted: 25 Apr 2013 12:00 AM PDT A wide variety of biological effects are induced in cells that are exposed to ionizing radiation. The expression changes of coding mRNA and non-coding micro-RNA have been implicated in irradiated cells. The involvement of other classes of non-coding RNAs (ncRNA), such as small nucleolar RNAs (snoRNAs), long ncRNAs (lncRNAs), and PIWI-interacting RNAs (piRNAs) in cells recovering from radiation-induced damage has not been examined. Thus, we investigated whether these ncRNA were undergoing changes in cells exposed to ionizing radiation. The modulation of ncRNAs expression was determined in human TK6 (p53 positive) and WTK1 (p53 negative) cells. The snoRNA host genes SNHG1, SNHG6, and SNHG11 were induced in TK6 cells. In WTK1 cells, SNHG1 was induced but SNHG6, and SNHG11 were repressed. SNHG7 was repressed in TK6 cells and was upregulated in WTK1 cells. The lncRNA MALAT1 and SOX2OT were induced in both TK6 and WTK1 cells and SRA1 was induced in TK6 cells only. Interestingly, the MIAT and PIWIL1 were not expressed in TK6 cells before or after the ionizing radiation treatment. The MIAT and PIWIL1 were upregulated in WTK1 cells. This data provides evidence that altered ncRNA expression is a part of the complex stress response operating in radiation-treated cells and this response depends on functional p53. |
Posted: 25 Apr 2013 12:00 AM PDT Thapsia laciniata Rouy (Apiaceae) produces irregular and regular sesquiterpenoids with thapsane and guaiene carbon skeletons, as found in other Apiaceae species. A transcriptomic analysis utilizing Illumina next-generation sequencing enabled the identification of novel genes involved in the biosynthesis of terpenoids in Thapsia. From 66.78 million HQ paired-end reads obtained from T. laciniata roots, 64.58 million were assembled into 76,565 contigs (N50: 1261 bp). Seventeen contigs were annotated as terpene synthases and five of these were predicted to be sesquiterpene synthases. Of the 67 contigs annotated as cytochromes P450, 18 of these are part of the CYP71 clade that primarily performs hydroxylations of specialized metabolites. Three contigs annotated as aldehyde dehydrogenases grouped phylogenetically with the characterized ALDH1 from Artemisia annua and three contigs annotated as alcohol dehydrogenases grouped with the recently described ADH1 from A. annua. ALDH1 and ADH1 were characterized as part of the artemisinin biosynthesis. We have produced a comprehensive EST dataset for T. laciniata roots, which contains a large sample of the T. laciniata transcriptome. These transcriptome data provide the foundation for future research into the molecular basis for terpenoid biosynthesis in Thapsia and on the evolution of terpenoids in Apiaceae. |
Entropy, Vol. 15, Pages 1516-1527: Phase-Space Position-Momentum Correlation and Potentials Posted: 25 Apr 2013 12:00 AM PDT Solutions to the radial Schr¨odinger equation of a particle in a quantum corral are used to probe how the statistical correlation between the position, and The momentum of the particle depends on the effective potential. The analysis is done via the Wigner function and its Shannon entropy. We show by comparison to the particle-in-a-box model that the attractive potential increases the magnitude of the correlation, while a repulsive potential decreases the magnitude of this correlation. Varying the magnitude of the repulsive potential yields that the correlation decreases with a stronger repulsive potential. |
1Password 3.8.21 - Powerful password manager; integrates with Web browsers and more. (Shareware) Posted: 25 Apr 2013 02:38 AM PDT 1Password is a password manager that uniquely brings you both security and convenience. It is the only program that provides anti-phishing protection and goes beyond password management by adding Web form filling and automatic strong password generation. Your confidential information, including passwords, identities, and credit cards, is kept secure using strong encryption. 1Password fully supports major Web browsers, including Safari, Firefox, and Chrome. All browser extensions share the data stored in the keychain which means you never need to manually copy your passwords between browsers or from the password manager to a browser ever again! 1Password has received numerous awards, including 4.5 mice from Macworld magazine, MacLife Editors pick, and was the Pick of Week on MacBreak Weekly by both Leo Laporte and Merlin Mann. 1Password also has a companion iPhone/iPod touch application available in iTunes App Store. Version 3.8.21:
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fp 6.1 - Unlimited length integers and more for Xcode C++. (Free) Posted: 25 Apr 2013 02:29 AM PDT fp is an Xcode C++ project which implements unlimited length integers, multi-precision floating point numbers, and multi-precision complex numbers. It can calculate the usual transcendental functions, including the Gamma function and many special functions. I am releasing it without a restrictive license. Version 6.1:
OS X 10.4.11 or later Download Now This posting includes an audio/video/photo media file: Download Now |
Posted: 25 Apr 2013 12:00 AM PDT Steady state fluctuation relations for nonequilibrium systems are under intense investigation because of their important practical implications in nanotechnology and biology. However the precise conditions under which they hold need clarification. Using the dissipation function, which is related to the entropy production of linear irreversible thermodynamics, we show time reversibility, ergodic consistency and a recently introduced form of correlation decay, called T-mixing, are sufficient conditions for steady state fluctuation relations to hold. Our results are not restricted to a particular model and show that the steady state fluctuation relation for the dissipation function holds near or far from equilibrium subject to these conditions. The dissipation function thus plays a comparable role in nonequilibrium systems to thermodynamic potentials in equilibrium systems. |
Entropy, Vol. 15, Pages 1486-1502: Discretization Based on Entropy and Multiple Scanning Posted: 25 Apr 2013 12:00 AM PDT In this paper we present entropy driven methodology for discretization. Recently, the original entropy based discretization was enhanced by including two options of selecting the best numerical attribute. In one option, Dominant Attribute, an attribute with the smallest conditional entropy of the concept given the attribute is selected for discretization and then the best cut point is determined. In the second option, Multiple Scanning, all attributes are scanned a number of times, and at the same time the best cut points are selected for all attributes. The results of experiments on 17 benchmark data sets, including large data sets, with 175 attributes or 25,931 cases, are presented. For comparison, the results of experiments on the same data sets using the global versions of well-known discretization methods of Equal Interval Width and Equal Frequency per Interval are also included. The entropy driven technique enhanced both of these methods by converting them into globalized methods. Results of our experiments show that the Multiple Scanning methodology is significantly better than both: Dominant Attribute and the better results of Globalized Equal Interval Width and Equal Frequency per Interval methods (using two-tailed test and 0.01 level of significance). |
Posted: 25 Apr 2013 12:00 AM PDT We examined the genetic variation and phylogeographic relationships among 10 populations of Lunella granulata from mainland China, Penghu Archipelago, Taiwan Island, and Japan using mitochondrial COI and 16S markers. A total of 45 haplotypes were obtained in 112 specimens, and relatively high levels of haplotype diversity (h = 0.903) and low levels of nucleotide diversity (π = 0.0046) were detected. Four major phylogenetic lineage clusters were revealed and were concordant with their geographic distribution, agreeing with the haplotype network. These results suggested that geographic barrier isolating effects were occurring among the populations. This hypothesis was also supported by a significant genetic differentiation index (FST = 0.709) and by a spatial analysis of molecular variance (SAMOVA) analysis. A mismatch distribution analysis, neutrality tests and Bayesian skyline plots found a single significant population expansion. This expansion occurred on the coast of mainland China before 20–17 ka. Consequently, although the dispersal ability of the planktonic stage and the circulation of ocean currents generally promote genetic exchanges among populations, L. granulata has tended to maintain distinct genetic groups that reflect the respective geographic origins of the constituent lineages. Although the circulation of ocean currents, in principle, may still play a role in determining the genetic composition of populations, long-distance migration between regions is difficult even at the planktonic stage. |
Posted: 25 Apr 2013 12:00 AM PDT Non-thermal plasmas are emerging as a novel tool for the treatment of living tissues for biological and medical purpose. In this study, we described the effect of 4 min dielectric barrier discharge (DBD) plasma on both T98G cancer and HEK normal cell lines in the presence of different concentrations of osmolytes. This treatment strategy shows a specific inhibitory effect of a 240 s plasma exposure in the presence of osmolytes against T98G brain cancer cells only, but not on HEK normal cells. Based on these interesting properties of osmolytes, a non-thermal plasma appears to be a potential anticancer treatment strategy for different kinds of cancers in the presence of osmolytes. |
Posted: 25 Apr 2013 12:00 AM PDT Zero-point vibrational level averaging for electron spin resonance (ESR) and muon spin resonance (µSR) hyperfine coupling constants (HFCCs) are computed for H and Mu isotopomers of the cyclohexadienyl radical. A local mode approximation previously developed for computation of the effect of replacement of H by D on 13C-NMR chemical shifts is used. DFT methods are used to compute the change in energy and HFCCs when the geometry is changed from the equilibrium values for the stretch and both bend degrees of freedom. This variation is then averaged over the probability distribution for each degree of freedom. The method is tested using data for the methylene group of C6H7, cyclohexadienyl radical and its Mu analog. Good agreement is found for the difference between the HFCCs for Mu and H of CHMu and that for H of CHMu and CH2 of the parent radical methylene group. All three of these HFCCs are the same in the absence of the zero point average, a one-parameter fit of the static HFCC, a(0), can be computed. That value, 45.2 Gauss, is compared to the results of several fixed geometry electronic structure computations. The HFCC values for the ortho, meta and para H atoms are then discussed. |
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