Games |
- Metabolites, Vol. 2, Pages 366-381: Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet
- Information, Vol. 3, Pages 229-255: The World Within Wikipedia: An Ecology of Mind
- Wondershare AllMyTube 3.0.0 - Download and convert YouTube videos.. (Shareware)
- Galaxy On Fire 2 1.0.4 - An outer space intergalactic adventure.. (Commercial)
- BitNami Gallery Stack 3.0.4-0 - Simplifies deployment of web-based photo album.. (Free)
- BitNami WordPress Stack 3.4-0 - Easy deployment of WordPress.. (Free)
- BitNami Tracks Stack 2.1-1 - Easy-to-install distribution of the Tracks application.. (Free)
- Daylight 1.8 - Show where sunlight falls for any place on Earth.. (Commercial)
- Shooting Blocks 2 1.1.2 - Multi-level strategy game. . (Demo)
- Hosts 0.1.1 - System preference pane to manage your host file.. (Free)
- Grim Tales: The Legacy Collector's Edition 1.0.1.10 - Hidden object mystery game. . (Demo)
- Crystals, Vol. 2, Pages 690-703: Silica-Metal Composite for Hydrogen Storage Applications
- Crystals, Vol. 2, Pages 675-689: Inorganic Amino-Nitro-Guanidinium Derivatives
- Pharmaceuticals, Vol. 5, Pages 643-654: Physical Factors Affecting Plasmid DNA Compaction in Stearylamine-Containing Nanoemulsions Intended for Gene Delivery
- Pharmaceutics, Vol. 4, Pages 314-333: Expression Profile of Drug and Nutrient Absorption Related Genes in Madin-Darby Canine Kidney (MDCK) Cells Grown under Differentiation Conditions
- IJERPH, Vol. 9, Pages 2241-2251: Psychosocial Correlates of Sunburn among Young Adult Women
- Marine Drugs, Vol. 10, Pages 1391-1399: Anti-Oxidative, Anti-Tumor-Promoting, and Anti-Carcinogensis Activities of Nitroastaxanthin and Nitrolutein, the Reaction Products of Astaxanthin and Lutein with Peroxynitrite
- Entropy, Vol. 14, Pages 1079-1102: Case Studies and Benchmark Examples for the Use of Grading Entropy in Geotechnics
- Remote Sensing, Vol. 4, Pages 1804-1819: Adaptive Slope Filtering of Airborne LiDAR Data in Urban Areas for Digital Terrain Model (DTM) Generation
- Remote Sensing, Vol. 4, Pages 1781-1803: Exploring the Use of MODIS NDVI-Based Phenology Indicators for Classifying Forest General Habitat Categories
| Posted: 18 Jun 2012 12:00 AM PDT The peroxisome proliferator-activated receptor-γ coactivators (PGC-1) are transcriptional coactivators with an important role in mitochondrial biogenesis and regulation of genes involved in the electron transport chain and oxidative phosphorylation in oxidative tissues including cardiac tissue. These coactivators are thought to play a key role in the development of obesity, type 2 diabetes and the metabolic syndrome. In this study we have used a combined metabolomic and lipidomic analysis of cardiac tissue from the PGC-1β null mouse to examine the effects of a high fat diet on this organ. Multivariate statistics readily separated tissue from PGC-1β null mice from their wild type controls either in gender specific models or in combined datasets. This was associated with an increase in creatine and a decrease in taurine in the null mouse, and an increase in myristic acid and a reduction in long chain polyunsaturated fatty acids for both genders. The most profound changes were detected by liquid chromatography mass spectrometry analysis of intact lipids with the tissue from the null mouse having a profound increase in a number of triglycerides. The metabolomic and lipodomic changes indicate PGC-1β has a profound influence on cardiac metabolism. |
| Information, Vol. 3, Pages 229-255: The World Within Wikipedia: An Ecology of Mind Posted: 18 Jun 2012 12:00 AM PDT Human beings inherit an informational culture transmitted through spoken and written language. A growing body of empirical work supports the mutual influence between language and categorization, suggesting that our cognitive-linguistic environment both reflects and shapes our understanding. By implication, artifacts that manifest this cognitive-linguistic environment, such asWikipedia, should represent language structure and conceptual categorization in a way consistent with human behavior. We use this intuition to guide the construction of a computational cognitive model, situated in Wikipedia, that generates semantic association judgments. Our unsupervised model combines information at the language structure and conceptual categorization levels to achieve state of the art correlation with human ratings on semantic association tasks including WordSimilarity-353, semantic feature production norms, word association, and false memory. |
| Wondershare AllMyTube 3.0.0 - Download and convert YouTube videos.. (Shareware) Posted: 18 Jun 2012 02:38 AM PDT  Wondershare AllMyTube for Mac is a very practical and easy-to-use tool designed for Mac OS users to free download YouTube and other internet videos and convert FLV videos on Mac OS X. It is both a Mac YouTube downloader and a Mac YouTube (FLV) video converter. AllMyTube for Mac Key Features 1. Download videos from internet
Version 3.0.0:
Note: The demo is for version 2.4.3. Version 3.0.0 can be purchased through the developer's website. Mac OS X 10.5 or later Download Now |
| Galaxy On Fire 2 1.0.4 - An outer space intergalactic adventure.. (Commercial) Posted: 18 Jun 2012 02:26 AM PDT  Galaxy On Fire 2TM Full HD is an epic, award-winning saga that set the standard for sci-fi on the App Store now blazes onto the Mac in Galaxy on Fire 2TM Full HD. With an App Store rating of 4.5 and a Metacritic score of 90, experience a rich, compelling outer space adventure of unprecedented depth that will set your Mac on fire. STORY A hyperdrive malfunction sends intergalactic adventurer and war hero Keith T. Maxwell tumbling through space and time. Awakening 35 years later at the far end of the galaxy, he quickly finds himself fighting for his life against a mysterious alien armada that is wreaking havoc on the warring races occupying this volatile sector of space. GAMEPLAY With fully redesigned controls that take advantage of mouse, keyboard and gamepads, Galaxy on Fire 2TM Full HD turns your Mac into the unrivalled, powerhouse HD gaming machine it was always meant to be. Follow the rich and engrossing storyline through a fully 3D, war-torn galaxy with over 10 hours of action-packed gameplay, or head off on an interplanetary journey of your own design: mining asteroids, trading ore and supplies, taking on mercenary missions, working as a pirate and manufacturing new weapons and equipment as you seek adventure and excitement on the final frontier. FEATURES GALAXY ON FIRE 2TM FULL HD FEATURES GALAXY ON FIRE 2TM IN THE PRESS: "Must have! Galaxy on Fire 2 is a supernova." Slidetoplay.com - 10/10 "Galaxy On Fire 2 is a game that pushes the format further than ever before." Appgamer.net - 9/10 "Galaxy on Fire 2 is a huge game… there really isn’t a more complete space game in the App Store." 148Apps.com â€" 4.5/5 SYSTEM REQUIREMENTS OSX: 10.6.6 Memory: 1 GB [4 GB recommended] CPU: Intel Core 2 Duo with 1.86 GHz [Intel Core i3 with 3 GHz recommended] HDD: 1.3 GB of free space [2 GB recommended] Video Chipset: Minimum 128 MB - no Support for Intel integrated graphic chipset Support for analog USB gamepad [Dual stick and 10-button gamepad recommended] EXTERNAL GOF2 Full HD Official Trailer - http://bit.ly/gof2hd-trailer Fishlabs YouTube Channel - http://www.youtube.com/fishlabsgames Follow Fishlabs on Facebook - http://www.facebook.com/fishlabs Fishlabs Homepage - http://www.fishlabs.net/ Version 1.0.4:
Mac OS X 10.6 or later Download Now |
| BitNami Gallery Stack 3.0.4-0 - Simplifies deployment of web-based photo album.. (Free) Posted: 17 Jun 2012 09:00 PM PDT  BitNami Gallery Stack greatly simplifies the deployment of Gallery and its required dependencies. It can be deployed using a native installer, as a virtual machine, in the cloud or as a module over an already installed infrastructure Stack. Gallery is a slick web-based photo album. It provides users with the ability to create and maintain their own albums in the album collection via an intuitive web interface. Photo management includes automatic thumbnail creation, image resizing, rotation, ordering, captioning and more. Albums can have read, write, and caption permissions per individual authenticated user for an additional level of privacy. The BitNami Gallery Stack native installers were packaged using BitRock's cross platform installer tool.
Mac OS X 10.4 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| BitNami WordPress Stack 3.4-0 - Easy deployment of WordPress.. (Free) Posted: 17 Jun 2012 09:00 PM PDT  BitNami WordPress Stack makes it easy to deploy WordPress, which is an open source, standards-compliant, fast, light and free personal publishing platform. The project was started in 2003 as a personal publishing platform, with a set of features designed to make the internet publishing experience easy. WordPress blogs now reach a combined 70 million global visitors and 300 million pageviews each month. The BitNami WordPress Stack native installers were packaged using BitRock's cross platform installer tool. Version 3.4-0:
Mac OS X 10.4 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| BitNami Tracks Stack 2.1-1 - Easy-to-install distribution of the Tracks application.. (Free) Posted: 17 Jun 2012 09:00 PM PDT  BitNami Tracks Stack Native Installer is an easy-to-install distribution of the Tracks application. It includes pre-configured, ready-to-run versions of Apache, MySQL, Ruby and Rails so users can get a Tracks installation up and running in minutes after answering a few questions. Windows, Linux and Mac OS X operating systems are supported. Tracks is a Ruby on Rails web-based application to help you implement David Allen's Getting Things Done methodology. Tracks is Open Source and licensed under the GNU GPL.
Download Now This posting includes an audio/video/photo media file: Download Now |
| Daylight 1.8 - Show where sunlight falls for any place on Earth.. (Commercial) Posted: 18 Jun 2012 02:20 AM PDT  Daylight for Mac is based on the popular Daylight apps for the iPad and iPhone. Daylight shows a big, bright, and beautiful map of the illuminated Earth, and the sunlight terminator.
Version 1.8:
Download Now |
| Shooting Blocks 2 1.1.2 - Multi-level strategy game. . (Demo) Posted: 18 Jun 2012 02:12 AM PDT  Shooting Blocks 2 takes you on an adventurous journey to a southern port and puts your strategic thinking to the test. You have to smash all empty boxes without damaging the rum boxes. Each time you break an empty box you get several points. By breaking a filled box you lose several points and a life. Bonus blocks which appears from time to time during the game can make the gaming experience much more exciting. What is more, there are some non-moving blocks that can't be destroyed and some bomb-blocks. By explosion such a bomb-block all the elements standing next to it fly away. Features:
Version 1.1.2: Release notes were unavailable when this listing was updated. Mac OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Hosts 0.1.1 - System preference pane to manage your host file.. (Free) Posted: 18 Jun 2012 02:07 AM PDT  Hosts is a system preference pane to manage your hosts file. Hosts add a preference pane to your system preferences which lets you toggle your host file entries on and off, as well as add and remove them. Hosts.prefpane likes to keep your hosts file clean. When an entry is toggled off, it is not commented out in the hosts file, but instead stored in the app's preferences storage. This means you will have to uncomment all your unused host entries and untoggle them in the prefpane if you want to use them. Comments are treated as comments and will never show up in the list of host entries! Ofcourse Hosts.prefpane will detect edits you made to the /etc/hosts directly and merge them into the listing. Backups of your hosts file is made in ~/Library/Application Support/Hosts. The backup or your hosts file from before you started using Hosts.prefpane is called hosts.orig and each session a backup is made called hosts.session. The default host entries that are needed by the OS are hidden and can not be edited using Hosts.prefpane.
Mac OS X 10.6.4 or later. Download Now |
| Grim Tales: The Legacy Collector's Edition 1.0.1.10 - Hidden object mystery game. . (Demo) Posted: 18 Jun 2012 01:55 AM PDT  In Grim Tales: The Legacy Collector's Edition, use your Hidden Object talents to track down your sister's family and save them! After being invited to the Christening of your sister's son, you arrive to find a deserted estate in Grim Tales: The Legacy! After getting married to the love of her life, it seems like a happy ending is right around the corner for your sister. However, all is not well. The sounds of ravenous beasts echo through the halls of the once great estate and your sister is missing! This is a special Collector's Edition release full of exclusive extras you won't find in the standard version. The Collector's Edition includes:
Version 1.0.1.10: Release notes were unavailable when this listing was updated. Mac OS X 10.5 or later Download Now This posting includes an audio/video/photo media file: Download Now |
| Crystals, Vol. 2, Pages 690-703: Silica-Metal Composite for Hydrogen Storage Applications Posted: 18 Jun 2012 12:00 AM PDT In spite of their favourable chemical characteristics, using AB5 alloys as fixed bed for hydrogen storage devices requires proper management of a number of technological aspects. Among these, the mechanical stability of metal particle grains under hydrogen cycling and the overall thermal conductivity of the material bed constitute crucial features. We developed by High Energy Ball Milling HEBM a mechanically stable silica-based AB5 composite with enhanced thermal conductivity. Here, focusing on the material's physical-chemical properties, we report on the silica-AB5 composite development and characterization. Particularly, we studied the material consolidation process, the resulting composite morphology and the system behaviour under hydrogen loading/unloading cycling. |
| Crystals, Vol. 2, Pages 675-689: Inorganic Amino-Nitro-Guanidinium Derivatives Posted: 18 Jun 2012 12:00 AM PDT 1-Amino-3-nitroguanidine (ANQ, 1) was synthesized by hydrazinolysis of nitroguanidine (NQ) with hydrazine hydrate. Four different amino-nitroguanidinium salts (chloride (2), bromide (3), iodide (4) and sulfate (5)) were synthesized and structurally characterized by low-temperature X-ray diffraction. The halides 2–4 could only be obtained crystalline as monohydrates. In addition, they were characterized by NMR and vibrational spectroscopy, elemental analysis and the sensitivities towards impact, friction and electrostatic discharge were determined. The compounds can be used in silver (AgX, X = Cl, Br, I) and barium (BaSO4) based metathesis reactions in order to form more complex salts of 1-amino-nitroguanidine. |
| Posted: 18 Jun 2012 12:00 AM PDT Cationic lipids have been used in the development of non-viral gene delivery systems as lipoplexes. Stearylamine, a cationic lipid that presents a primary amine group when in solution, is able to compact genetic material by electrostatic interactions. In dispersed systems such as nanoemulsions this lipid anchors on the oil/water interface confering a positive charge to them. The aim of this work was to evaluate factors that influence DNA compaction in cationic nanoemulsions containing stearylamine. The influence of the stearylamine incorporation phase (water or oil), time of complexation, and different incubation temperatures were studied. The complexation rate was assessed by electrophoresis migration on agarose gel 0.7%, and nanoemulsion and lipoplex characterization was done by Dynamic Light Scattering (DLS). The results demonstrate that the best DNA compaction process occurs after 120 min of complexation, at low temperature (4 ± 1 °C), and after incorporation of the cationic lipid into the aqueous phase. Although the zeta potential of lipoplexes was lower than the results found for basic nanoemulsions, the granulometry did not change. Moreover, it was demonstrated that lipoplexes are suitable vehicles for gene delivery. |
| Posted: 18 Jun 2012 12:00 AM PDT The expression levels of genes involved in drug and nutrient absorption were evaluated in the Madin-Darby Canine Kidney (MDCK) in vitro drug absorption model. MDCK cells were grown on plastic surfaces (for 3 days) or on Transwell® membranes (for 3, 5, 7, and 9 days). The expression profile of genes including ABC transporters, SLC transporters, and cytochrome P450 (CYP) enzymes was determined using the Affymetrix® Canine GeneChip®. Expression of genes whose probe sets passed a stringent confirmation process was examined. Expression of a few transporter (MDR1, PEPT1 and PEPT2) genes in MDCK cells was confirmed by RT-PCR. The overall gene expression profile was strongly influenced by the type of support the cells were grown on. After 3 days of growth, expression of 28% of the genes was statistically different (1.5-fold cutoff, p < 0.05) between the cells grown on plastic and Transwell® membranes. When cells were differentiated on Transwell® membranes, large changes in gene expression profile were observed during the early stages, which then stabilized after 5–7 days. Only a small number of genes encoding drug absorption related SLC, ABC, and CYP were detected in MDCK cells, and most of them exhibited low hybridization signals. Results from this study provide valuable reference information on endogenous gene expression in MDCK cells that could assist in design of drug-transporter and/or drug-enzyme interaction studies, and help interpret the contributions of various transporters and metabolic enzymes in studies with MDCK cells. |
| IJERPH, Vol. 9, Pages 2241-2251: Psychosocial Correlates of Sunburn among Young Adult Women Posted: 18 Jun 2012 12:00 AM PDT Skin cancer is an increasingly common disease, particularly among young adult women. Sunburn early in life is a risk factor for skin cancer. Few studies have reported on psychosocial correlates of sunburn. The current study consisted of an online survey of undergraduate women from a university in the northeastern part of the USA. A logistic regression demonstrated that young women who reported a history of four or more sunburns were significantly more likely to report fair skin, higher perceived susceptibility to skin cancer, greater perceived benefits of tanning (e.g., appearance enhancement), lower perceived control over skin protection, and more frequent sunscreen use. Sunbathing was not associated with a greater number of sunburns. These results suggest that young women who sunburn more often possess other skin cancer risk factors, are aware of their susceptibility to skin cancer, and try to use sunscreen, but feel limited control over their skin protection behavior and are not less likely to sunbathe than others. Therefore, interventions are needed to assist high risk young women in asserting more control over their sun protection behavior and perhaps improve the effectiveness of the sunscreen or other skin protection methods they do employ. |
| Posted: 18 Jun 2012 12:00 AM PDT Astaxanthin captured peroxynitrite to form nitroastaxanthins. 15-Nitroastaxanthin was a major reaction product of astaxanthin with peroxynitrite. Here, the anti-oxidative, anti-tumor-promoting, and anti-carcinogensis activities of 15-nitroastaxanthin were investigated. In addition to astaxanthin, 15-nitroastaxanthin showed excellent singlet oxygen quenching activity. Furthermore, 15-nitroastaxanthin showed inhibitory effects of in vitro Epstein-Barr virus early antigen activation and two-stage carcinogensis on mouse skin papillomas. These activities were slightly higher than those of astaxanthin. Similar results were obtained for the 15-nitrolutein, a major reaction product of lutein with peroxynitrite. |
| Posted: 18 Jun 2012 12:00 AM PDT The grading entropy concept can be adapted to the field of geotechnics, to establish criteria for phenomena such as particle packing, particle migration and filtering, through a quantified expression of the order/disorder in the grain size distribution, in terms of two entropy-based parameters. In this paper, the grading entropy theory is applied in some geotechnical case studies, which serve as benchmark examples to illustrate its application to the characterisation of piping, softening and dispersive soils, and to filtering problems in the context of a leachate collection system for a landfill site. Further, since unstable cohesive (dispersive) soils are generally improved by lime, the effect of lime addition is also considered, on the basis of some measurements and a further application of the grading entropy concept, which allows evolutions in the entropy of a soil to be considered as its grading is modified. The examples described support the hypothesis that the potential for soil erosion and particle migration can be reliably identified using grading entropy parameters derived from grading curve data, and applied through an established soil structure stability criteria and a filtering rule. It is shown that lime modification is not necessarily helpful in stabilizing against particle migration. |
| Posted: 18 Jun 2012 12:00 AM PDT A filtering algorithm is proposed that accurately extracts ground data from airborne light detection and ranging (LiDAR) measurements and generates an estimated digital terrain model (DTM). The proposed algorithm utilizes planar surface features and connectivity with locally lowest points to improve the extraction of ground points (GPs). A slope parameter used in the proposed algorithm is updated after an initial estimation of the DTM, and thus local terrain information can be included. As a result, the proposed algorithm can extract GPs from areas where different degrees of slope variation are interspersed. Specifically, along roads and streets, GPs were extracted from urban areas, from hilly areas such as forests, and from flat area such as riverbanks. Validation using reference data showed that, compared with commercial filtering software, the proposed algorithm extracts GPs with higher accuracy. Therefore, the proposed filtering algorithm effectively generates DTMs, even for dense urban areas, from airborne LiDAR data. |
| Posted: 18 Jun 2012 12:00 AM PDT The cost effective monitoring of habitats and their biodiversity remains a challenge to date. Earth Observation (EO) has a key role to play in mapping habitat and biodiversity in general, providing tools for the systematic collection of environmental data. The recent GEO-BON European Biodiversity Observation Network project (EBONE) established a framework for an integrated biodiversity monitoring system. Underlying this framework is the idea of integrating in situ with EO and a habitat classification scheme based on General Habitat Categories (GHC), designed with an Earth Observation-perspective. Here we report on EBONE work that explored the use of NDVI-derived phenology metrics for the identification and mapping of Forest GHCs. Thirty-one phenology metrics were extracted from MODIS NDVI time series for Europe. Classifications to discriminate forest types were performed based on a Random Forests™ classifier in selected regions. Results indicate that date phenology metrics are generally more significant for forest type discrimination. The achieved class accuracies are generally not satisfactory, except for coniferous forests in homogeneous stands (77–82%). The main causes of low classification accuracies were identified as (i) the spatial resolution of the imagery (250 m) which led to mixed phenology signals; (ii) the GHC scheme classification design, which allows for parcels of heterogeneous covers, and (iii) the low number of the training samples available from field surveys. A mapping strategy integrating EO-based phenology with vegetation height information is expected to be more effective than a purely phenology-based approach. |
| You are subscribed to email updates from Games To stop receiving these emails, you may unsubscribe now. | Email delivery powered by Google |
| Google Inc., 20 West Kinzie, Chicago IL USA 60610 | |
Комментариев нет:
Отправить комментарий