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- Viruses, Vol. 4, Pages 1104-1115: Legume Lectins Inhibit Human Parainfluenza Virus Type 2 Infection by Interfering with the Entry
- Viruses, Vol. 4, Pages 1093-1103: Molecular Identification of Chronic Bee Paralysis Virus Infection in Apis mellifera Colonies in Japan
- IJMS, Vol. 13, Pages 8126-8141: Elongation Factor 1β' Gene from Spodoptera exigua: Characterization and Function Identification through RNA Interference
- The story of UK gaming industry's early years may never be told. But you can help make sure it is
- SmuginForiPhoto 1.2 - Upload your images and videos from iPhoto to SmugMug.. (Demo)
- MissingMediaBurner 0.6.2 - Burn info to CD-R/RW and DVD-R/RW media.. (Free)
- MidiKit 3.4 - MIDI batch editor and browser.. (Shareware)
- IJMS, Vol. 13, Pages 8112-8125: Synthesis and Spectral Evaluation of Some Unsymmetrical Mesoporphyrinic Complexes
- Remote Sensing, Vol. 4, Pages 1974-1994: High Resolution Mapping of Peatland Hydroperiod at a High-Latitude Swedish Mire
- Remote Sensing, Vol. 4, Pages 1963-1973: The Impact of Subscale Inhomogeneity on Oxygen A Band Cloud-Top Pressure Estimates: Using ESA’s MERIS as a Proxy for DSCOVR-EPIC
- Remote Sensing, Vol. 4, Pages 1947-1962: Utility of Satellite and Aerial Images for Quantification of Canopy Cover and Infilling Rates of the Invasive Woody Species Honey Mesquite (Prosopis Glandulosa) on Rangeland
- Remote Sensing, Vol. 4, Pages 1929-1946: Distribution Patterns of Burned Areas in the Brazilian Biomes: An Analysis Based on Satellite Data for the 2002–2010 Period
- Quantum Conundrum aims to defeat physics by turning itself into a TV show
- Cycle PDF to Word Converter 1.5.0 - Convert PDF. (Shareware)
- Chess Club ready for championship
- Max Payne turns 8 innocuous situations into a violent bloodbath
- South Korea's shutdown law under fire
- Square Enix has highest salary average among game companies in Japan
- Game Masters: Tetsuya Mizuguchi
- ACMI Game Masters - Tetsuya Mizuguchi Interview
| Posted: 29 Jun 2012 12:00 AM PDT Three lectins with different sugar binding specificities were investigated for anti-viral activity against human parainfluenza virus type 2 (hPIV-2). The lectins, concanavalin A (Con A), lens culinaris agglutinin (LCA) and peanut agglutinin (PNA), inhibited cell fusion and hemadsorption induced by hPIV-2. Virus nucleoprotein (NP) gene synthesis was largely inhibited, but fusion (F) and hemagglutinin-neuraminidase (HN) gene syntheses were not. An indirect immunofluorescence study showed that Con A inhibited virus NP, F and HN protein syntheses, but LCA did not completely inhibit them, and that PNA inhibited only NP protein synthesis. Using a recombinant green fluorescence protein-expressing hPIV-2, without matrix protein (rghPIV-2ΔM), it was found that virus entry into the cells was not completely prevented. The lectins considerably reduced the number of viruses released compared with that of virus infected cells. The lectins bound to cell surface within 10 min, and many aggregates were observed at 30 min. Con A and LCA slightly disrupted actin microfilaments and microtubules, but PNA had almost no effect on them. These results indicated that the inhibitory effects of the lectins were caused mainly by the considerable prevention of virus adsorption to the cells by the lectin binding to their receptors. |
| Posted: 29 Jun 2012 12:00 AM PDT Chronic bee paralysis virus (CBPV) infection causes chronic paralysis and loss of workers in honey bee colonies around the world. Although CBPV shows a worldwide distribution, it had not been molecularly detected in Japan. Our investigation of Apis mellifera and Apis cerana japonica colonies with RT-PCR has revealed CBPV infection in A. mellifera but not A. c. japonica colonies in Japan. The prevalence of CBPV is low compared with that of other viruses: deformed wing virus (DWV), black queen cell virus (BQCV), Israel acute paralysis virus (IAPV), and sac brood virus (SBV), previously reported in Japan. Because of its low prevalence (5.6%) in A. mellifera colonies, the incidence of colony losses by CBPV infection must be sporadic in Japan. The presence of the (−) strand RNA in dying workers suggests that CBPV infection and replication may contribute to their symptoms. Phylogenetic analysis demonstrates a geographic separation of Japanese isolates from European, Uruguayan, and mainland US isolates. The lack of major exchange of honey bees between Europe/mainland US and Japan for the recent 26 years (1985–2010) may have resulted in the geographic separation of Japanese CBPV isolates. |
| Posted: 29 Jun 2012 12:00 AM PDT Elongation factor (EF) is a key regulation factor for translation in many organisms, including plants, bacteria, fungi, animals and insects. To investigate the nature and function of elongation factor 1β' from Spodoptera exigua (SeEF-1β'), its cDNA was cloned. This contained an open reading frame of 672 nucleotides encoding a protein of 223 amino acids with a predicted molecular weight of 24.04 kDa and pI of 4.53. Northern blotting revealed that SeEF-1β' mRNA is expressed in brain, epidermis, fat body, midgut, Malpighian tubules, ovary and tracheae. RT-PCR revealed that SeEF-1β' mRNA is expressed at different levels in fat body and whole body during different developmental stages. In RNAi experiments, the survival rate of insects injected with SeEF-1β' dsRNA was 58.7% at 36 h after injection, which was significantly lower than three control groups. Other elongation factors and transcription factors were also influenced when EF-1β' was suppressed. The results demonstrate that SeEF-1β' is a key gene in transcription in S. exigua. |
| The story of UK gaming industry's early years may never be told. But you can help make sure it is Posted: 29 Jun 2012 03:17 AM PDT Crowd-sourced funding has seemingly become an overnight success, what with Kickstarter affording Double Fine about a zillion pounds a few weeks back. |
| SmuginForiPhoto 1.2 - Upload your images and videos from iPhoto to SmugMug.. (Demo) Posted: 29 Jun 2012 02:59 AM PDT  With SmuginForiPhoto, you can upload your images and videos from iPhoto to SmugMug.
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| MissingMediaBurner 0.6.2 - Burn info to CD-R/RW and DVD-R/RW media.. (Free) Posted: 29 Jun 2012 02:46 AM PDT  MissingMediaBurner is a tool that allows you to burn information to CD-R/RW and DVD-R/RW drives. Some of the drives supported include the Yamaha-CDR10x, Plextor, Sony-CDU920 and 948, Toshiba and more. Version 0.6.2 adds the following:
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| MidiKit 3.4 - MIDI batch editor and browser.. (Shareware) Posted: 29 Jun 2012 02:40 AM PDT  MidiKit is a MIDI file browser/editor and batch processor. The browser quickly displays the most significant information about MIDI files. The editor allows native SMF editing with unlimited undo/redo capacity. Finally, MidiKit allows you to apply several operations on your MIDI files by batch processing entire disks at a time. Version 3.4:
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| Posted: 29 Jun 2012 12:00 AM PDT Synthesis and spectral evaluation of new zinc and copper unsymmetrical mesoporphyrinic complexes are reported. Zn(II)-5-(4-acetoxy-3-methoxyphenyl)-10,15,20-tris-(4-carboxymethylphenyl)porphyrin, Zn(II)-5-[(3,4-methylenedioxy)phenyl]-10,15,20-tris-(4-carboxymethylphenyl)porphyrin, Cu(II)-5-(4-acetoxy-3-methoxyphenyl)-10,15,20-tris-(4-carboxymethylphenyl)porphyrin and Cu(II)-5-[(3,4-methylenedioxy)phenyl]-10,15,20-tris-(4-carboxymethylphenyl)porphyrin were synthesized using microwave-assisted synthesis. The complexes were characterized by elemental analysis, FT-IR, UV-Vis, EPR and NMR spectroscopy, which fully confirmed their structure. The spectral absorption properties of the porphyrinic complexes were studied in solvents with different polarities. Fluorescence emission and singlet oxygen formation quantum yields were evaluated for the compounds under study, revealing high yields for the zinc derivatives. The copper complexes are not emissive and only display residual capacity for singlet oxygen formation. |
| Posted: 29 Jun 2012 12:00 AM PDT Monitoring high latitude wetlands is required to understand feedbacks between terrestrial carbon pools and climate change. Hydrological variability is a key factor driving biogeochemical processes in these ecosystems and effective assessment tools are critical for accurate characterization of surface hydrology, soil moisture, and water table fluctuations. Operational satellite platforms provide opportunities to systematically monitor hydrological variability in high latitude wetlands. The objective of this research application was to integrate high temporal frequency Synthetic Aperture Radar (SAR) and high spatial resolution Light Detection and Ranging (LiDAR) observations to assess hydroperiod at a mire in northern Sweden. Geostatistical and polarimetric (PLR) techniques were applied to determine spatial structure of the wetland and imagery at respective scales (0.5 m to 25 m). Variogram, spatial regression, and decomposition approaches characterized the sensitivity of the two platforms (SAR and LiDAR) to wetland hydrogeomorphology, scattering mechanisms, and data interrelationships. A Classification and Regression Tree (CART), based on random forest, fused multi-mode (fine-beam single, dual, quad pol) Phased Array L-band Synthetic Aperture Radar (PALSAR) and LiDAR-derived elevation to effectively map hydroperiod attributes at the Swedish mire across an aggregated warm season (May–September, 2006–2010). Image derived estimates of water and peat moisture were sensitive (R2 = 0.86) to field measurements of water table depth (cm). Peat areas that are underlain by permafrost were observed as areas with fluctuating soil moisture and water table changes. |
| Posted: 29 Jun 2012 12:00 AM PDT Medium Spectral Resolution Imaging Spectrometer (MERIS) oxygen A band measurements were used as a proxy for the Earth Polychromatic Imaging Camera (EPIC),to be launched on NASA's Deep Space Climate Observatory (DSCOVR). The high spatial resolution of MERIS (1 × 1 km2) is exploited to study the effects of subscale spatialheterogeneity of clouds on the cloud-top pressure retrieved at the coarser spatial resolutionof EPIC (10 × 10 km2). In general, for a sub-scale cloud fraction less than 1, a shift of cloud-top pressure toward the middle atmosphere is found, with a low-bias for highclouds and a high-bias for low clouds. In addition, the deviation is found to be a function of surface reflectance. The subscale variability of fully clouded EPIC pixels causes a weak underestimation of cloud-top pressure, when compared to averaged high-resolution retrievals. |
| Posted: 29 Jun 2012 12:00 AM PDT Woody plant encroachment into grasslands and rangelands is a world-wide phenomenon but detailed descriptions of changes in geographical distribution and infilling rates have not been well documented at large land scales. Remote sensing with either aerial or satellite images may provide a rapid means for accomplishing this task. Our objective was to compare the accuracy and utility of two types of images with contrasting spatial resolutions (1-m aerial and 30-m satellite) for classifying woody and herbaceous canopy cover and determining woody infilling rates in a large area of rangeland (800 km2) in north Texas that has been invaded by honey mesquite (Prosopis glandulosa). Accuracy assessment revealed that the overall accuracies for the classification of four land cover types (mesquite, grass, bare ground and other) were 94 and 87% with kappa coefficients of 0.89 and 0.77 for the 1-m and 30-m images, respectively. Over the entire area, the 30-m image over-estimated mesquite canopy cover by 9 percentage units (10 vs. 19%) and underestimated grass canopy cover by the same amount when compared to the 1-m image. The 30-m resolution image typically overestimated mesquite canopy cover within 225 4-ha sub-cells that contained a range of mesquite covers (1–70%) when compared to the 1-m image classification and was not suitable for quantifying infilling rates of this native invasive species. Documenting woody and non-woody canopy cover on large land areas is important for developing integrated, regional-scale management strategies for rangeland and grassland regions that have been invaded by woody plants. |
| Posted: 29 Jun 2012 12:00 AM PDT Fires modify the structure of vegetation communities, the carbon and water cycles, the soil's chemistry, and affect the climate system. Within this context, this work aimed to understand the distribution patterns of burned areas in Brazil, during the period of 2002 to 2010, taking into consideration each one of the six Brazilian biomes (Amazon, Caatinga, Cerrado, Atlantic Forest, Pampa and Pantanal) and the respective major land cover classes. Data from the MODIS MCD45A1 product (burned area), as well as thermal anomalies (MOD14 and MYD14) and precipitation (TRMM), were analyzed according to the 2002 Brazilian official land cover and land use map (PROBIO). The Brazilian savanna biome, known as Cerrado, presented the largest concentration of burned areas detected by MODIS (73%), followed by the Amazon (14%), Pantanal (6%), Atlantic Forest (4%), Caatinga (3%), and Pampa (0,06%) biomes. Indeed, in the years of 2007 and 2010, 90% and 92% of Brazil's burned areas were concentrated in the Cerrado and Amazon biomes, respectively. TRMM data indicated that during these two years there was a significant influence of La Niña, causing low rainfall in the Amazon, Cerrado, Caatinga, and Atlantic Forest biomes. Regarding the land cover classes, approximately 81% of the burned areas occurred over remnant vegetation areas. Although no unequivocal correlation can be established between burned areas and new land conversions, the conspicuous concentration of fire scars, particularly in Amazon–Cerrado transition (i.e., the Arc of Deforestation) is certainly not a simple coincidence. Such patterns and trends corroborate the need of improved territorial governance, in addition to the implementation of systematic fire warning and preventive systems. |
| Quantum Conundrum aims to defeat physics by turning itself into a TV show Posted: 29 Jun 2012 02:40 AM PDT If a long and painful history of crossovers has taught us anything, it's that games don't translate well to TV. Aiming to change the reputation of shows |
| Cycle PDF to Word Converter 1.5.0 - Convert PDF. (Shareware) Posted: 29 Jun 2012 02:28 AM PDT  Cycle PDF to Word Converter is a powerful and intuitive application that lets you convert PDF to Microsoft Word document. It starts with an extremely neat and clear interface, you can finish all the setting and preview PDFs right in the app directly. You can import as many PDFs as you like or convert any particular pages flexibly. It can convert PDF with multi column, graphics, formatting, tables, and preserve everything perfectly in Microsoft Word. Editing or reusing PDF in Word cannot be easier. Here are some of the key features: Incredibly easy-to-use
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| Chess Club ready for championship Posted: 29 Jun 2012 01:38 AM PDT Croydon Chess Club ready for championship 29 Jun 12 @ 05:00am by Angus Livingston IT IS intense strategy played at breakneck speed. This posting includes an audio/video/photo media file: Download Now |
| Max Payne turns 8 innocuous situations into a violent bloodbath Posted: 29 Jun 2012 02:09 AM PDT To be honest the guy's a bit of a liability |
| South Korea's shutdown law under fire Posted: 29 Jun 2012 12:03 AM PDT Korean game companies like NCsoft and Neowiz are leading the charge against the country's Shutdown Law.
Parents and game companies are starting to throw lawsuits at the South Korean government concerning the country's Shutdown Law. The law itself prohibits minors under sixteen from playing games for six hours starting at 12 midnight in an effort to use their time more productively. According to Korean site This Is Game (via Kotaku), game makers that have currently thrown down the gauntlet are NCsoft, Neowiz, and Nexon. An unverified Korean parent and teenager organization representing culture (possibly the group MoonHwaYunDae) also filed for a lawsuit against the government. On a related note, South Korea's Ministry of Gender Equality and Family said that the law is the "bare minimum" required to protect teenagers from managing their time badly and making unsound decisions based on their upbringing. Recently, the PSN Store in Korea was affected by the law. Read and Post Comments | Get the full article at GameSpot "South Korea's shutdown law under fire" was posted by Jonathan Toyad on Fri, 29 Jun 2012 00:03:02 -0700 |
| Square Enix has highest salary average among game companies in Japan Posted: 28 Jun 2012 11:30 PM PDT Final Fantasy publishers hold top spot, above Sony, Nintendo, and Sega.
Japanese salary and income analysing company Nensyu Labo recently revealed a ranking chart for the companies with the highest average salary for its employees (via Andriasang). Square Enix is at the top, with employees getting an average salary of 21.68 million yen peryear ($273,057). This was followed up by Sony, with an average of 9.23 million yen ($116,253), and Nintendo with 9.14 million yen ($115,117). Sega Sammy Corporation was placed fourth, with a salary average of 8.22 million yen, while Konami and Namco Bandai were just behind with 6.78 and 6.40 million, respectively. The top ten list is just below: 1. Square Enix -- 21.68 million Nensyu Labo stated that it compiles its data based off public filings from each company. Read and Post Comments | Get the full article at GameSpot "Square Enix has highest salary average among game companies in Japan" was posted by Jonathan Toyad on Thu, 28 Jun 2012 23:30:58 -0700 |
| Game Masters: Tetsuya Mizuguchi Posted: 28 Jun 2012 10:23 PM PDT Our interview with the creative mind behind Rez, Lumines, and Child of Eden.
Get the full article at GameSpot "Game Masters: Tetsuya Mizuguchi" was posted by Laura Parker on Thu, 28 Jun 2012 22:23:58 -0700 |
| ACMI Game Masters - Tetsuya Mizuguchi Interview Posted: 28 Jun 2012 10:18 PM PDT Rez and Child of Eden designer Tetsuya Mizuguchi speaks about how video games are the art of reflecting wants, desires and basic instincts in human beings.
Read and Post Comments | Get the full article at GameSpot "ACMI Game Masters - Tetsuya Mizuguchi Interview" was posted by edmondt on Thu, 28 Jun 2012 22:18:56 -0700 |
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